Total number of protein in "GO:0021987" GO term: 77
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKIRIN2-201 | AKIRIN2 | Q53H80 | Akirin-2 | chr6 | GO:0021987 | Not Cancer Driver | No | 19 | 0.0935960591133004 | 124 | 11 | 0.0541871921182266 | 0 |
| ARHGAP11B-208 | ARHGAP11B | Q3KRB8 | Inactive Rho GTPase-activating protein 11B | chr15 | GO:0021987 | Not Cancer Driver | No | 12 | 0.0449438202247191 | 17 | 0 | 0.0 | 0 |
| ASCL1-201 | ASCL1 | P50553 | Achaete-scute homolog 1 | chr12 | GO:0021987 | Not Cancer Driver | No | 26 | 0.1101694915254237 | 183 | 18 | 0.0762711864406779 | 0 |
| ASPM-203 | ASPM | Q8IZT6 | Abnormal spindle-like microcephaly-associated protein | chr1 | GO:0021987 | Not Cancer Driver | No | 380 | 0.1092896174863388 | 427 | 47 | 0.0135174000575208 | 0 |
| ATIC-201 | ATIC | P31939 | Bifunctional purine biosynthesis protein ATIC | chr2 | GO:0021987 | Census | Yes | 49 | 0.0827702702702702 | 25 | 1 | 0.0016891891891891 | 1 |
| ATOH1-201 | ATOH1 | Q92858 | Transcription factor ATOH1 | chr4 | GO:0021987 | Not Cancer Driver | No | 54 | 0.1525423728813559 | 329 | 46 | 0.1299435028248587 | 0 |
| BAX-202 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0021987 | Census | Yes | 24 | 0.125 | 39 | 2 | 0.0104166666666666 | 0 |
| BBS1-201 | BBS1 | Q8NFJ9 | Bardet-Biedl syndrome 1 protein | chr11 | GO:0021987 | Not Cancer Driver | No | 52 | 0.087689713322091 | 100 | 9 | 0.0151770657672849 | 11 |
| BBS2-201 | BBS2 | Q9BXC9 | Bardet-Biedl syndrome 2 protein | chr16 | GO:0021987 | Not Cancer Driver | No | 60 | 0.0832177531206657 | 76 | 8 | 0.0110957004160887 | 20 |
| BBS4-201 | BBS4 | Q96RK4 | Bardet-Biedl syndrome 4 protein | chr15 | GO:0021987 | Not Cancer Driver | No | 44 | 0.0847784200385356 | 111 | 14 | 0.0269749518304431 | 9 |
| BNIP3-201 | BNIP3 | Q12983 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | chr10 | GO:0021987 | Not Cancer Driver | No | 16 | 0.0824742268041237 | 131 | 11 | 0.056701030927835 | 0 |
| BTBD3-202 | BTBD3 | Q9Y2F9 | BTB/POZ domain-containing protein 3 | chr20 | GO:0021987 | Not Cancer Driver | No | 59 | 0.1130268199233716 | 54 | 2 | 0.003831417624521 | 0 |
| CCDC85C-201 | CCDC85C | A6NKD9 | Coiled-coil domain-containing protein 85C | chr14 | GO:0021987 | Not Cancer Driver | No | 3 | 0.0071599045346062 | 305 | 3 | 0.0071599045346062 | 0 |
| CDH2-201 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0021987 | Not Cancer Driver | No | 182 | 0.2008830022075055 | 464 | 107 | 0.1181015452538631 | 7 |
| CDON-216 | CDON | Q4KMG0 | Cell adhesion molecule-related/down-regulated by oncogenes | chr11 | GO:0021987 | Not Cancer Driver | No | 120 | 0.0932400932400932 | 444 | 42 | 0.0326340326340326 | 5 |
| CEP120-201 | CEP120 | Q8N960 | Centrosomal protein of 120 kDa | chr5 | GO:0021987 | Not Cancer Driver | No | 70 | 0.0709939148073022 | 449 | 35 | 0.0354969574036511 | 1 |
| CNTNAP2-201 | CNTNAP2 | Q9UHC6 | Contactin-associated protein-like 2 | chr7 | GO:0021987 | Census | Yes | 470 | 0.3531179564237415 | 162 | 63 | 0.0473328324567994 | 0 |
| COL3A1-201 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0021987 | Census | Yes | 49 | 0.0334242837653478 | 1183 | 6 | 0.0040927694406548 | 86 |
| CRK-201 | CRK | P46108 | Adapter molecule crk | chr17 | GO:0021987 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 197 | 19 | 0.0625 | 0 |
| CRKL-201 | CRKL | P46109 | Crk-like protein | chr22 | GO:0021987 | Not Cancer Driver | No | 24 | 0.0792079207920792 | 160 | 17 | 0.0561056105610561 | 0 |
| CSNK2A2-201 | CSNK2A2 | P19784 | Casein kinase II subunit alpha' | chr16 | GO:0021987 | Not Cancer Driver | No | 25 | 0.0714285714285714 | 13 | 1 | 0.0028571428571428 | 0 |
| ENST00000419755 | BBS1 | Q8NFJ9 | Bardet-Biedl syndrome 1 protein | chr11 | GO:0021987 | Not Cancer Driver | No | 52 | 0.0825396825396825 | 132 | 7 | 0.0111111111111111 | 11 |
| ENST00000685924 | ARHGAP11B | Q3KRB8 | Inactive Rho GTPase-activating protein 11B | chr15 | GO:0021987 | Not Cancer Driver | No | 12 | 0.0449438202247191 | 17 | 0 | 0.0 | 0 |
| FAT4-202 | FAT4 | Q6V0I7 | Protocadherin Fat 4 | chr4 | GO:0021987 | Census, Compendium | Yes | 992 | 0.1990768613285169 | 1402 | 285 | 0.0571944611679711 | 7 |
| FLNA-202 | FLNA | P21333 | Filamin-A | chrX | GO:0021987 | Census | Yes | 314 | 0.1186248583301851 | 1460 | 162 | 0.0612013600302229 | 29 |
| FOXP2-201 | FOXP2 | O15409 | Forkhead box protein P2 | chr7 | GO:0021987 | Not Cancer Driver | No | 76 | 0.1062937062937063 | 446 | 44 | 0.0615384615384615 | 1 |
| GART-203 | GART | P22102 | Trifunctional purine biosynthetic protein adenosine-3 | chr21 | GO:0021987 | Not Cancer Driver | No | 66 | 0.0653465346534653 | 50 | 4 | 0.0039603960396039 | 0 |
| GRIA1-201 | GRIA1 | P42261 | Glutamate receptor 1 | chr5 | GO:0021987 | Not Cancer Driver | No | 252 | 0.2781456953642384 | 104 | 37 | 0.0408388520971302 | 3 |
| H2AX-202 | H2AX | P16104 | Histone H2AX | chr11 | GO:0021987 | Not Cancer Driver | No | 19 | 0.1328671328671328 | 68 | 8 | 0.0559440559440559 | 0 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0021987 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| KCNA1-201 | KCNA1 | Q09470 | Potassium voltage-gated channel subfamily A member 1 | chr12 | GO:0021987 | Not Cancer Driver | No | 139 | 0.2808080808080808 | 69 | 29 | 0.0585858585858585 | 17 |
| KCNA2-201 | KCNA2 | P16389 | Potassium voltage-gated channel subfamily A member 2 | chr1 | GO:0021987 | Not Cancer Driver | No | 76 | 0.1523046092184369 | 83 | 12 | 0.0240480961923847 | 6 |
| KDM1A-201 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0021987 | Not Cancer Driver | No | 48 | 0.056338028169014 | 291 | 21 | 0.0246478873239436 | 3 |
| KIF14-201 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | GO:0021987 | Not Cancer Driver | No | 145 | 0.0879854368932038 | 777 | 65 | 0.0394417475728155 | 2 |
| KIF26A-202 | KIF26A | Q9ULI4 | Kinesin-like protein KIF26A | chr14 | GO:0021987 | Not Cancer Driver | No | 123 | 0.065356004250797 | 1443 | 89 | 0.0472901168969181 | 0 |
| LHX2-201 | LHX2 | P50458 | LIM/homeobox protein Lhx2 | chr9 | GO:0021987 | Not Cancer Driver | No | 40 | 0.0985221674876847 | 203 | 18 | 0.0443349753694581 | 0 |
| MCPH1-201 | MCPH1 | Q8NEM0 | Microcephalin | chr8 | GO:0021987 | Not Cancer Driver | No | 84 | 0.1005988023952095 | 454 | 46 | 0.0550898203592814 | 1 |
| MDK-203 | MDK | P21741 | Midkine | chr11 | GO:0021987 | Not Cancer Driver | No | 13 | 0.0909090909090909 | 20 | 1 | 0.0069930069930069 | 0 |
| MECP2-201 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0021987 | Not Cancer Driver | No | 44 | 0.0905349794238683 | 482 | 43 | 0.088477366255144 | 32 |
| MGARP-201 | MGARP | Q8TDB4 | Protein MGARP | chr4 | GO:0021987 | Not Cancer Driver | No | 15 | 0.0625 | 209 | 14 | 0.0583333333333333 | 0 |
| MKKS-201 | MKKS | Q9NPJ1 | Molecular chaperone MKKS | chr20 | GO:0021987 | Not Cancer Driver | No | 35 | 0.0614035087719298 | 7 | 0 | 0.0 | 22 |
| NARS1-201 | NARS1 | O43776 | Asparagine--tRNA ligase, cytoplasmic | chr18 | GO:0021987 | Not Cancer Driver | No | 35 | 0.0638686131386861 | 104 | 11 | 0.0200729927007299 | 4 |
| NCOA1-202 | NCOA1 | Q15788 | Nuclear receptor coactivator 1 | chr2 | GO:0021987 | Census, Compendium | Yes | 135 | 0.0936849410131853 | 1217 | 107 | 0.0742539902845246 | 0 |
| NDE1-201 | NDE1 | Q9NXR1 | Nuclear distribution protein nudE homolog 1 | chr16 | GO:0021987 | Not Cancer Driver | No | 34 | 0.1014925373134328 | 316 | 33 | 0.0985074626865671 | 0 |
| NEFL-201 | NEFL | P07196 | Neurofilament light polypeptide | chr8 | GO:0021987 | Not Cancer Driver | No | 0 | 0.0 | 285 | 0 | 0.0 | 10 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0021987 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NOTCH2NLA-201 | NOTCH2NLA | Q7Z3S9 | Notch homolog 2 N-terminal-like protein A | chr1 | GO:0021987 | Not Cancer Driver | No | 49 | 0.2076271186440678 | 17 | 1 | 0.0042372881355932 | 0 |
| NOTCH2NLB-201 | NOTCH2NLA | Q7Z3S9 | Notch homolog 2 N-terminal-like protein A | chr1 | GO:0021987 | Not Cancer Driver | No | 0 | 0.0 | 16 | 0 | 0.0 | 0 |
| NOTCH2NLC-202 | NOTCH2NLC | P0DPK4 | Notch homolog 2 N-terminal-like protein C | chr1 | GO:0021987 | Not Cancer Driver | No | 0 | 0.0 | 24 | 0 | 0.0 | 0 |
| NPY-201 | NPY | P01303 | Pro-neuropeptide Y | chr7 | GO:0021987 | Not Cancer Driver | No | 29 | 0.2989690721649484 | 46 | 20 | 0.2061855670103092 | 0 |
| NSUN5-201 | NSUN5 | Q96P11 | 28S rRNA (cytosine-C(5))-methyltransferase | chr7 | GO:0021987 | Not Cancer Driver | No | 38 | 0.0885780885780885 | 47 | 5 | 0.0116550116550116 | 0 |
| NTRK2-246 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0021987 | Not Cancer Driver | No | 103 | 0.1253041362530413 | 117 | 14 | 0.0170316301703163 | 1 |
| PAFAH1B1-202 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0021987 | Not Cancer Driver | No | 37 | 0.0902439024390243 | 83 | 11 | 0.0268292682926829 | 7 |
| PALS1-201 | PALS1 | Q8N3R9 | Protein PALS1 | chr14 | GO:0021987 | Not Cancer Driver | No | 50 | 0.074074074074074 | 338 | 21 | 0.0311111111111111 | 0 |
| PAX5-201 | PAX5 | Q02548 | Paired box protein Pax-5 | chr9 | GO:0021987 | Census | Yes | 69 | 0.1764705882352941 | 292 | 53 | 0.1355498721227621 | 1 |
| PHACTR1-201 | PHACTR1 | Q9C0D0 | Phosphatase and actin regulator 1 | chr6 | GO:0021987 | Not Cancer Driver | No | 44 | 0.0758620689655172 | 448 | 36 | 0.0620689655172413 | 3 |
| PLCB1-201 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0021987 | Not Cancer Driver | No | 264 | 0.2171052631578947 | 484 | 85 | 0.0699013157894736 | 0 |
| PPP1R9B-202 | PPP1R9B | Q96SB3 | Neurabin-2 | chr17 | GO:0021987 | Not Cancer Driver | No | 37 | 0.0452876376988984 | 698 | 27 | 0.033047735618115 | 0 |
| PTPRS-201 | PTPRS | Q13332 | Receptor-type tyrosine-protein phosphatase S | chr19 | GO:0021987 | Not Cancer Driver | No | 191 | 0.0980492813141683 | 834 | 88 | 0.0451745379876796 | 0 |
| SLC2A1-203 | SLC2A1 | P11166 | Solute carrier family 2, facilitated glucose transporter member 1 | chr1 | GO:0021987 | Not Cancer Driver | No | 43 | 0.0873983739837398 | 13 | 2 | 0.0040650406504065 | 44 |
| SLC38A2-201 | SLC38A2 | Q96QD8 | Sodium-coupled neutral amino acid symporter 2 | chr12 | GO:0021987 | Not Cancer Driver | No | 42 | 0.0830039525691699 | 9 | 1 | 0.0019762845849802 | 0 |
| SMO-201 | SMO | Q99835 | Protein smoothened | chr7 | GO:0021987 | Census, Compendium | Yes | 88 | 0.1118170266836086 | 242 | 20 | 0.025412960609911 | 1 |
| SRD5A1-201 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0021987 | Not Cancer Driver | No | 26 | 0.1003861003861003 | 0 | 0 | 0.0 | 0 |
| SRGAP2C-202 | SRGAP2C | P0DJJ0 | SLIT-ROBO Rho GTPase-activating protein 2C | chr1 | GO:0021987 | Not Cancer Driver | No | 0 | 0.0 | 136 | 0 | 0.0 | 0 |
| TACC1-202 | TACC1 | O75410 | Transforming acidic coiled-coil-containing protein 1 | chr8 | GO:0021987 | Not Cancer Driver | No | 64 | 0.0795031055900621 | 660 | 52 | 0.0645962732919254 | 0 |
| TACC2-210 | TACC2 | O95359 | Transforming acidic coiled-coil-containing protein 2 | chr10 | GO:0021987 | Not Cancer Driver | No | 383 | 0.1299185888738127 | 2752 | 363 | 0.1231343283582089 | 0 |
| TACC3-201 | TACC3 | Q9Y6A5 | Transforming acidic coiled-coil-containing protein 3 | chr4 | GO:0021987 | Not Cancer Driver | No | 76 | 0.0906921241050119 | 719 | 67 | 0.0799522673031026 | 0 |
| TBR1-201 | TBR1 | Q16650 | T-box brain protein 1 | chr2 | GO:0021987 | Not Cancer Driver | No | 65 | 0.095307917888563 | 413 | 42 | 0.0615835777126099 | 4 |
| TH-206 | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0021987 | Not Cancer Driver | No | 48 | 0.0909090909090909 | 151 | 17 | 0.0321969696969696 | 38 |
| TMEM14B-202 | TMEM14B | Q9NUH8 | Transmembrane protein 14B | chr6 | GO:0021987 | Not Cancer Driver | No | 13 | 0.1140350877192982 | 0 | 0 | 0.0 | 0 |
| TRAPPC9-201 | TRAPPC9 | Q96Q05 | Trafficking protein particle complex subunit 9 | chr8 | GO:0021987 | Not Cancer Driver | No | 136 | 0.1184668989547038 | 133 | 20 | 0.0174216027874564 | 0 |
| TSC1-201 | TSC1 | Q92574 | Hamartin | chr9 | GO:0021987 | Census, Compendium | Yes | 94 | 0.0807560137457044 | 735 | 53 | 0.0455326460481099 | 11 |
| TUBA1A-202 | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | GO:0021987 | Not Cancer Driver | No | 45 | 0.0997782705099778 | 52 | 6 | 0.0133037694013303 | 6 |
| TUBB2A-201 | TUBB2A | Q13885 | Tubulin beta-2A chain | chr6 | GO:0021987 | Not Cancer Driver | No | 32 | 0.0719101123595505 | 70 | 5 | 0.0112359550561797 | 2 |
| TUBB2B-201 | TUBB2B | Q9BVA1 | Tubulin beta-2B chain | chr6 | GO:0021987 | Not Cancer Driver | No | 33 | 0.0741573033707865 | 68 | 4 | 0.0089887640449438 | 10 |
| WDR62-201 | WDR62 | O43379 | WD repeat-containing protein 62 | chr19 | GO:0021987 | Not Cancer Driver | No | 136 | 0.0895915678524374 | 801 | 71 | 0.0467720685111989 | 5 |
| YWHAE-201 | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | GO:0021987 | Census | Yes | 24 | 0.0941176470588235 | 41 | 1 | 0.0039215686274509 | 0 |