Total number of protein in "GO:0030163" GO term: 64
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAMTS13-206 | ADAMTS13 | Q76LX8 | A disintegrin and metalloproteinase with thrombospondin motifs 13 | chr9 | GO:0030163 | Not Cancer Driver | No | 138 | 0.0967063770147161 | 286 | 26 | 0.0182200420462508 | 42 |
| CAPN3-205 | CAPN3 | P20807 | Calpain-3 | chr15 | GO:0030163 | Not Cancer Driver | No | 79 | 0.0962241169305724 | 169 | 8 | 0.0097442143727162 | 46 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0030163 | Census | Yes | 19 | 0.0685920577617328 | 64 | 1 | 0.003610108303249 | 0 |
| CASP7-203 | CASP7 | P55210 | Caspase-7 | chr10 | GO:0030163 | Not Cancer Driver | No | 28 | 0.0924092409240924 | 75 | 7 | 0.0231023102310231 | 0 |
| CBLB-201 | CBLB | Q13191 | E3 ubiquitin-protein ligase CBL-B | chr3 | GO:0030163 | Census | Yes | 126 | 0.1283095723014256 | 565 | 77 | 0.0784114052953156 | 0 |
| CD2AP-201 | CD2AP | Q9Y5K6 | CD2-associated protein | chr6 | GO:0030163 | Not Cancer Driver | No | 51 | 0.0798122065727699 | 458 | 38 | 0.0594679186228482 | 0 |
| CHEK2-206 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0030163 | Census, Compendium | Yes | 72 | 0.1325966850828729 | 157 | 19 | 0.0349907918968692 | 11 |
| CLN5-201 | CLN5 | O75503 | Ceroid-lipofuscinosis neuronal protein 5 | chr13 | GO:0030163 | Not Cancer Driver | No | 25 | 0.0698324022346368 | 16 | 1 | 0.0027932960893854 | 11 |
| CLN6-201 | CLN6 | Q9NWW5 | Ceroid-lipofuscinosis neuronal protein 6 | chr15 | GO:0030163 | Not Cancer Driver | No | 23 | 0.0739549839228295 | 13 | 0 | 0.0 | 23 |
| CLN8-201 | CLN8 | Q9UBY8 | Protein CLN8 | chr8 | GO:0030163 | Not Cancer Driver | No | 35 | 0.1223776223776223 | 16 | 3 | 0.0104895104895104 | 15 |
| CMA1-202 | CMA1 | P23946 | Chymase | chr14 | GO:0030163 | Not Cancer Driver | No | 39 | 0.1578947368421052 | 9 | 1 | 0.0040485829959514 | 0 |
| CPB2-201 | CPB2 | Q96IY4 | Carboxypeptidase B2 | chr13 | GO:0030163 | Not Cancer Driver | No | 42 | 0.0992907801418439 | 2 | 0 | 0.0 | 0 |
| CPN1-201 | CPN1 | P15169 | Carboxypeptidase N catalytic chain | chr10 | GO:0030163 | Not Cancer Driver | No | 80 | 0.1746724890829694 | 125 | 23 | 0.0502183406113537 | 1 |
| CTRL-205 | CTRL | P40313 | Chymotrypsin-like protease CTRL-1 | chr16 | GO:0030163 | Not Cancer Driver | No | 25 | 0.0946969696969697 | 0 | 0 | 0.0 | 0 |
| DAB2IP-203 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0030163 | Not Cancer Driver | No | 95 | 0.0798990748528175 | 682 | 49 | 0.04121110176619 | 0 |
| DENND3-201 | DENND3 | A2RUS2 | DENN domain-containing protein 3 | chr8 | GO:0030163 | Not Cancer Driver | No | 138 | 0.1151919866444073 | 121 | 17 | 0.0141903171953255 | 0 |
| DPP3-209 | DPP3 | Q9NY33 | Dipeptidyl peptidase 3 | chr11 | GO:0030163 | Not Cancer Driver | No | 86 | 0.1166892808683853 | 65 | 14 | 0.0189959294436906 | 0 |
| ELANE-201 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0030163 | Not Cancer Driver | No | 31 | 0.1161048689138576 | 18 | 1 | 0.0037453183520599 | 65 |
| EXT1-201 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0030163 | Census | Yes | 75 | 0.1005361930294906 | 60 | 7 | 0.0093833780160857 | 8 |
| FYN-202 | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0030163 | Not Cancer Driver | No | 64 | 0.1191806331471136 | 71 | 11 | 0.0204841713221601 | 0 |
| GGA1-203 | GGA1 | Q9UJY5 | ADP-ribosylation factor-binding protein GGA1 | chr22 | GO:0030163 | Not Cancer Driver | No | 57 | 0.0892018779342723 | 385 | 23 | 0.0359937402190923 | 0 |
| GGA3-201 | GGA3 | Q9NZ52 | ADP-ribosylation factor-binding protein GGA3 | chr17 | GO:0030163 | Not Cancer Driver | No | 51 | 0.0705394190871369 | 421 | 29 | 0.0401106500691562 | 0 |
| GRIN2A-201 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0030163 | Census, Compendium | Yes | 439 | 0.2998633879781421 | 507 | 172 | 0.1174863387978142 | 32 |
| HAMP-201 | HAMP | P81172 | Hepcidin | chr19 | GO:0030163 | Not Cancer Driver | No | 7 | 0.0833333333333333 | 4 | 0 | 0.0 | 4 |
| HTRA2-201 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0030163 | Compendium | Yes | 33 | 0.0720524017467248 | 127 | 7 | 0.0152838427947598 | 2 |
| IDE-201 | IDE | P14735 | Insulin-degrading enzyme | chr10 | GO:0030163 | Not Cancer Driver | No | 65 | 0.0637880274779195 | 96 | 6 | 0.0058881256133464 | 0 |
| IL17RA-201 | IL17RA | Q96F46 | Interleukin-17 receptor A | chr22 | GO:0030163 | Not Cancer Driver | No | 70 | 0.0808314087759815 | 304 | 14 | 0.0161662817551963 | 0 |
| LNPEP-201 | LNPEP | Q9UIQ6 | Leucyl-cystinyl aminopeptidase | chr5 | GO:0030163 | Not Cancer Driver | No | 80 | 0.0780487804878048 | 103 | 5 | 0.0048780487804878 | 0 |
| LONP1-201 | LONP1 | P36776 | Lon protease homolog, mitochondrial | chr19 | GO:0030163 | Not Cancer Driver | No | 75 | 0.0782064650677789 | 178 | 16 | 0.0166840458811261 | 10 |
| LPCAT1-201 | LPCAT1 | Q8NF37 | Lysophosphatidylcholine acyltransferase 1 | chr5 | GO:0030163 | Not Cancer Driver | No | 67 | 0.1254681647940075 | 66 | 7 | 0.0131086142322097 | 0 |
| LRSAM1-201 | LRSAM1 | Q6UWE0 | E3 ubiquitin-protein ligase LRSAM1 | chr9 | GO:0030163 | Not Cancer Driver | No | 71 | 0.0982019363762102 | 240 | 24 | 0.0331950207468879 | 1 |
| MAGEA2-210 | MAGEA2B | P43356 | Melanoma-associated antigen 2 | chrX | GO:0030163 | Not Cancer Driver | No | 0 | 0.0 | 113 | 0 | 0.0 | 0 |
| MAGEA2B-212 | MAGEA2B | P43356 | Melanoma-associated antigen 2 | chrX | GO:0030163 | Not Cancer Driver | No | 0 | 0.0 | 113 | 0 | 0.0 | 0 |
| MAGEC2-201 | MAGEC2 | Q9UBF1 | Melanoma-associated antigen C2 | chrX | GO:0030163 | Not Cancer Driver | No | 140 | 0.3753351206434316 | 131 | 53 | 0.1420911528150134 | 0 |
| MME-201 | MME | P08473 | Neprilysin | chr3 | GO:0030163 | Not Cancer Driver | No | 156 | 0.208 | 40 | 17 | 0.0226666666666666 | 4 |
| MMP2-201 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0030163 | Not Cancer Driver | No | 101 | 0.153030303030303 | 29 | 5 | 0.0075757575757575 | 2 |
| MMP20-201 | MMP20 | O60882 | Matrix metalloproteinase-20 | chr11 | GO:0030163 | Not Cancer Driver | No | 58 | 0.1200828157349896 | 70 | 7 | 0.0144927536231884 | 0 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0030163 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
| NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0030163 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
| NQO1-201 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | GO:0030163 | Not Cancer Driver | No | 11 | 0.0401459854014598 | 10 | 0 | 0.0 | 0 |
| P2RX7-202 | P2RX7 | Q99572 | P2X purinoceptor 7 | chr12 | GO:0030163 | Not Cancer Driver | No | 37 | 0.0621848739495798 | 16 | 1 | 0.0016806722689075 | 0 |
| PAPPA-201 | PAPPA | Q13219 | Pappalysin-1 | chr9 | GO:0030163 | Not Cancer Driver | No | 294 | 0.1807006760909649 | 239 | 36 | 0.0221266133988936 | 0 |
| PDLIM2-207 | PDLIM2 | Q96JY6 | PDZ and LIM domain protein 2 | chr8 | GO:0030163 | Not Cancer Driver | No | 40 | 0.1136363636363636 | 289 | 34 | 0.096590909090909 | 0 |
| PGPEP1-202 | PGPEP1 | Q9NXJ5 | Pyroglutamyl-peptidase 1 | chr19 | GO:0030163 | Not Cancer Driver | No | 16 | 0.0765550239234449 | 0 | 0 | 0.0 | 0 |
| PJA1-203 | PJA1 | Q8NG27 | E3 ubiquitin-protein ligase Praja-1 | chrX | GO:0030163 | Not Cancer Driver | No | 89 | 0.1384136858475894 | 527 | 73 | 0.1135303265940902 | 0 |
| PPT1-219 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | GO:0030163 | Not Cancer Driver | No | 27 | 0.088235294117647 | 0 | 0 | 0.0 | 22 |
| PRSS16-201 | PRSS16 | Q9NQE7 | Thymus-specific serine protease | chr6 | GO:0030163 | Not Cancer Driver | No | 63 | 0.122568093385214 | 26 | 5 | 0.0097276264591439 | 0 |
| RELA-202 | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0030163 | Compendium | Yes | 53 | 0.0961887477313974 | 401 | 32 | 0.058076225045372 | 0 |
| RIPK1-201 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0030163 | Compendium | Yes | 59 | 0.0879284649776453 | 277 | 28 | 0.0417287630402384 | 1 |
| RNF165-201 | ARK2C | Q6ZSG1 | E3 ubiquitin-protein ligase ARK2C | chr18 | GO:0030163 | Not Cancer Driver | No | 51 | 0.1473988439306358 | 225 | 33 | 0.0953757225433526 | 0 |
| RNF5-203 | RNF5 | Q99942 | E3 ubiquitin-protein ligase RNF5 | chr6 | GO:0030163 | Not Cancer Driver | No | 12 | 0.0666666666666666 | 69 | 1 | 0.0055555555555555 | 0 |
| SERPINE2-201 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0030163 | Not Cancer Driver | No | 55 | 0.1381909547738693 | 0 | 0 | 0.0 | 0 |
| SIAH1-203 | SIAH1 | Q8IUQ4 | E3 ubiquitin-protein ligase SIAH1 | chr16 | GO:0030163 | Not Cancer Driver | No | 22 | 0.0780141843971631 | 28 | 2 | 0.0070921985815602 | 5 |
| SLC16A3-213 | SLC16A3 | O15427 | Monocarboxylate transporter 4 | chr17 | GO:0030163 | Not Cancer Driver | No | 29 | 0.0623655913978494 | 43 | 3 | 0.0064516129032258 | 0 |
| SLC6A17-201 | SLC6A17 | Q9H1V8 | Sodium-dependent neutral amino acid transporter SLC6A17 | chr1 | GO:0030163 | Not Cancer Driver | No | 93 | 0.1279229711141678 | 68 | 9 | 0.0123796423658872 | 2 |
| SLC6A7-201 | SLC6A7 | Q99884 | Sodium-dependent proline transporter | chr5 | GO:0030163 | Not Cancer Driver | No | 63 | 0.0990566037735849 | 19 | 2 | 0.0031446540880503 | 0 |
| SQSTM1-202 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | GO:0030163 | Not Cancer Driver | No | 41 | 0.0931818181818181 | 271 | 24 | 0.0545454545454545 | 30 |
| ST14-201 | ST14 | Q9Y5Y6 | Suppressor of tumorigenicity 14 protein | chr11 | GO:0030163 | Not Cancer Driver | No | 86 | 0.1005847953216374 | 47 | 5 | 0.0058479532163742 | 1 |
| TPP1-201 | TPP1 | O14773 | Tripeptidyl-peptidase 1 | chr11 | GO:0030163 | Not Cancer Driver | No | 56 | 0.0994671403197158 | 92 | 7 | 0.0124333925399644 | 34 |
| TRAF2-201 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0030163 | Not Cancer Driver | No | 51 | 0.1017964071856287 | 4 | 1 | 0.0019960079840319 | 0 |
| TRIM24-201 | TRIM24 | O15164 | Transcription intermediary factor 1-alpha | chr7 | GO:0030163 | Census, Compendium | Yes | 90 | 0.0857142857142857 | 537 | 45 | 0.0428571428571428 | 0 |
| UCHL3-201 | UCHL3 | P15374 | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | chr13 | GO:0030163 | Not Cancer Driver | No | 20 | 0.0869565217391304 | 61 | 1 | 0.0043478260869565 | 0 |
| USE1-201 | USE1 | Q9NZ43 | Vesicle transport protein USE1 | chr19 | GO:0030163 | Not Cancer Driver | No | 27 | 0.1042471042471042 | 102 | 19 | 0.0733590733590733 | 0 |
| UTP25-202 | UTP25 | Q68CQ4 | U3 small nucleolar RNA-associated protein 25 homolog | chr1 | GO:0030163 | Not Cancer Driver | No | 76 | 0.1005291005291005 | 281 | 14 | 0.0185185185185185 | 0 |