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Total number of protein in "GO:0030307" GO term:  87

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM10-201 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0030307 Not Cancer Driver No 73 0.0975935828877005 156 18 0.0240641711229946 4
ADAM17-201 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0030307 Not Cancer Driver No 63 0.0764563106796116 182 17 0.020631067961165 0
AKAP6-201 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0030307 Not Cancer Driver No 295 0.1272100043122035 1464 188 0.0810694264769297 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0030307 Census, Compendium Yes 99 0.20625 158 19 0.0395833333333333 4
ARMC12-202 ARMC12 Q5T9G4 Armadillo repeat-containing protein 12 chr6 GO:0030307 Not Cancer Driver No 40 0.1176470588235294 8 0 0.0 0
AVP-201 AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0030307 Not Cancer Driver No 11 0.0670731707317073 26 1 0.0060975609756097 26
AVPR1A-201 AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0030307 Not Cancer Driver No 84 0.200956937799043 69 17 0.0406698564593301 0
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0030307 Census, Compendium Yes 21 0.0878661087866108 73 5 0.0209205020920502 0
BRAT1-201 BRAT1 Q6PJG6 BRCA1-associated ATM activator 1 chr7 GO:0030307 Not Cancer Driver No 82 0.099878197320341 102 11 0.0133982947624847 0
CD38-201 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0030307 Not Cancer Driver No 39 0.13 3 0 0.0 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0030307 Not Cancer Driver No 21 0.1099476439790576 23 1 0.0052356020942408 1
CDKN2AIP-203 CDKN2AIP Q9NXV6 CDKN2A-interacting protein chr4 GO:0030307 Not Cancer Driver No 18 0.0310344827586206 352 15 0.0258620689655172 0
CEP43-202 CEP43 O95684 Centrosomal protein 43 chr6 GO:0030307 Not Cancer Driver No 32 0.0802005012531328 274 27 0.0676691729323308 0
CIB1-201 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0030307 Not Cancer Driver No 16 0.0837696335078534 6 1 0.0052356020942408 0
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0030307 Not Cancer Driver No 47 0.1202046035805626 75 6 0.0153452685421994 4
CSNK2A3-201 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 GO:0030307 Not Cancer Driver No 47 0.1202046035805626 76 9 0.0230179028132992 0
CXCL16-201 CXCL16 Q9H2A7 C-X-C motif chemokine 16 chr17 GO:0030307 Not Cancer Driver No 23 0.0905511811023622 121 12 0.0472440944881889 0
DDX3X-244 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0030307 Census, Compendium Yes 91 0.1374622356495468 302 32 0.0483383685800604 18
DDX49-201 DDX49 Q9Y6V7 Probable ATP-dependent RNA helicase DDX49 chr19 GO:0030307 Not Cancer Driver No 35 0.072463768115942 79 4 0.0082815734989648 0
DERL2-201 DERL2 Q9GZP9 Derlin-2 chr17 GO:0030307 Not Cancer Driver No 13 0.0543933054393305 15 0 0.0 0
DNPH1-201 DNPH1 O43598 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 chr6 GO:0030307 Not Cancer Driver No 12 0.0689655172413793 49 2 0.0114942528735632 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 GO:0030307 Census, Compendium Yes 346 0.2859504132231405 223 30 0.024793388429752 1
EIF4G1-202 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0030307 Not Cancer Driver No 157 0.0981863664790494 1080 103 0.0644152595372107 2
EIF4G2-201 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0030307 Not Cancer Driver No 80 0.0882028665931642 382 38 0.041896361631753 0
ENST00000705256 CEP43 O95684 Centrosomal protein 43 chr6 GO:0030307 Not Cancer Driver No 0 0.0 0 0 0.0 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0030307 Not Cancer Driver No 21 0.1099476439790576 23 1 0.0052356020942408 1
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0030307 Census, Compendium Yes 249 0.198406374501992 315 32 0.0254980079681274 1
EXOSC2-204 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:0030307 Not Cancer Driver No 13 0.0443686006825938 47 1 0.0034129692832764 2
EXOSC4-201 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0030307 Not Cancer Driver No 26 0.1061224489795918 23 0 0.0 0
EXOSC9-201 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0030307 Not Cancer Driver No 30 0.0683371298405467 155 11 0.0250569476082004 1
EXTL3-201 EXTL3 O43909 Exostosin-like 3 chr8 GO:0030307 Not Cancer Driver No 101 0.1099020674646354 111 17 0.0184983677910772 5
F2-201 F2 P00734 Prothrombin chr11 GO:0030307 Not Cancer Driver No 85 0.1366559485530546 98 20 0.0321543408360128 9
FXN-203 FXN Q16595 Frataxin, mitochondrial chr9 GO:0030307 Not Cancer Driver No 17 0.0809523809523809 75 1 0.0047619047619047 8
H3-3A-203 H3-3B P84243 Histone H3.3 chr1 GO:0030307 Not Cancer Driver No 27 0.1985294117647058 51 21 0.1544117647058823 18
H3-3B-201 H3-3B P84243 Histone H3.3 chr17 GO:0030307 Not Cancer Driver No 26 0.1911764705882352 51 14 0.1029411764705882 18
H3-5-201 H3-5 Q6NXT2 Histone H3.3C chr12 GO:0030307 Not Cancer Driver No 27 0.2 50 7 0.0518518518518518 0
HBEGF-201 HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0030307 Not Cancer Driver No 11 0.0528846153846153 63 2 0.0096153846153846 0
HDGFL2-208 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0030307 Not Cancer Driver No 26 0.0387481371087928 622 26 0.0387481371087928 0
HPN-210 HPN P05981 Serine protease hepsin chr19 GO:0030307 Not Cancer Driver No 49 0.1175059952038369 12 2 0.0047961630695443 0
HYAL1-204 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0030307 Not Cancer Driver No 30 0.0689655172413793 9 0 0.0 1
IGFBP1-201 IGFBP1 P08833 Insulin-like growth factor-binding protein 1 chr7 GO:0030307 Not Cancer Driver No 29 0.1119691119691119 42 7 0.027027027027027 0
IL2-201 IL2 P60568 Interleukin-2 chr4 GO:0030307 Census Yes 16 0.1045751633986928 6 0 0.0 0
IL9-201 IL9 P15248 Interleukin-9 chr5 GO:0030307 Not Cancer Driver No 7 0.0486111111111111 4 0 0.0 0
INO80-209 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0030307 Compendium Yes 137 0.0880462724935732 682 67 0.0430591259640102 0
INS-202 INS P01308 Insulin chr11 GO:0030307 Not Cancer Driver No 7 0.0636363636363636 5 1 0.009090909090909 19
KDM2B-202 KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0030307 Not Cancer Driver No 142 0.1062874251497006 620 64 0.0479041916167664 0
KLHL22-201 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0030307 Not Cancer Driver No 75 0.1182965299684542 50 7 0.0110410094637223 0
KRT17-201 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 GO:0030307 Not Cancer Driver No 68 0.1574074074074074 162 28 0.0648148148148148 13
LGI1-202 LGI1 O95970 Leucine-rich glioma-inactivated protein 1 chr10 GO:0030307 Not Cancer Driver No 64 0.1149012567324955 3 1 0.0017953321364452 16
MAP2K5-201 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0030307 Not Cancer Driver No 26 0.0580357142857142 85 6 0.0133928571428571 0
MAPKAP1-201 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0030307 Not Cancer Driver No 57 0.1091954022988505 173 17 0.0325670498084291 0
MFSD2A-201 MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0030307 Not Cancer Driver No 37 0.0681399631675874 36 3 0.005524861878453 7
MLST8-232 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 GO:0030307 Not Cancer Driver No 24 0.0736196319018405 45 3 0.00920245398773 0
MMP14-201 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0030307 Not Cancer Driver No 50 0.0859106529209622 120 6 0.0103092783505154 1
MTOR-201 MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0030307 Census, Compendium Yes 298 0.1169085916045508 298 28 0.0109846998823067 15
MTPN-201 MTPN P58546 Myotrophin chr7 GO:0030307 Not Cancer Driver No 7 0.059322033898305 11 3 0.0254237288135593 0
N6AMT1-201 N6AMT1 Q9Y5N5 Methyltransferase N6AMT1 chr21 GO:0030307 Not Cancer Driver No 33 0.1542056074766355 20 3 0.014018691588785 0
NCBP1-202 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0030307 Not Cancer Driver No 66 0.0835443037974683 89 7 0.0088607594936708 0
PABIR1-201 PABIR1 Q96E09 PPP2R1A-PPP2R2A-interacting phosphatase regulator 1 chr9 GO:0030307 Not Cancer Driver No 13 0.0452961672473867 285 13 0.0452961672473867 0
PRR5-202 PRR5 P85299 Proline-rich protein 5 chr22 GO:0030307 Not Cancer Driver No 41 0.1056701030927835 177 18 0.0463917525773195 0
PRSS2-201 PRSS2 P07478 Trypsin-2 chr7 GO:0030307 Not Cancer Driver No 0 0.0 9 0 0.0 0
PSMD10-201 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0030307 Not Cancer Driver No 13 0.0575221238938053 53 4 0.0176991150442477 0
PTK2B-201 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0030307 Not Cancer Driver No 117 0.1159563924677899 263 23 0.0227948463825569 0
RICTOR-202 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 GO:0030307 Not Cancer Driver No 144 0.0843091334894613 365 34 0.0199063231850117 0
RPS6KA1-204 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0030307 Not Cancer Driver No 71 0.0965986394557823 178 22 0.0299319727891156 0
RPS6KA3-201 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0030307 Compendium Yes 72 0.0972972972972973 146 10 0.0135135135135135 13
RPTOR-201 RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0030307 Not Cancer Driver No 149 0.1116104868913857 242 18 0.0134831460674157 0
S100A8-202 S100A8 P05109 Protein S100-A8 chr1 GO:0030307 Not Cancer Driver No 17 0.1827956989247312 8 4 0.043010752688172 0
S100A9-201 S100A9 P06702 Protein S100-A9 chr1 GO:0030307 Not Cancer Driver No 16 0.1403508771929824 76 8 0.0701754385964912 0
SDCBP-201 SDCBP O00560 Syntenin-1 chr8 GO:0030307 Not Cancer Driver No 23 0.0771812080536912 17 1 0.0033557046979865 0
SFN-201 SFN P31947 14-3-3 protein sigma chr1 GO:0030307 Not Cancer Driver No 16 0.064516129032258 75 3 0.0120967741935483 0
SFRP1-201 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0030307 Not Cancer Driver No 31 0.0987261146496815 39 4 0.0127388535031847 0
SFRP2-201 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0030307 Not Cancer Driver No 37 0.1254237288135593 1 0 0.0 0
SLC25A33-201 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0030307 Not Cancer Driver No 21 0.0654205607476635 4 0 0.0 0
SLC44A4-202 SLC44A4 Q53GD3 Choline transporter-like protein 4 chr6 GO:0030307 Not Cancer Driver No 60 0.0845070422535211 24 3 0.004225352112676 1
SLC9A1-201 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0030307 Not Cancer Driver No 57 0.0699386503067484 252 17 0.0208588957055214 1
SPHK1-210 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0030307 Not Cancer Driver No 29 0.0755208333333333 25 0 0.0 0
SUPV3L1-201 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0030307 Not Cancer Driver No 46 0.0585241730279898 140 9 0.0114503816793893 0
TAF9B-201 TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:0030307 Not Cancer Driver No 30 0.1195219123505976 189 22 0.0876494023904382 0
TEAD1-206 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:0030307 Not Cancer Driver No 35 0.0821596244131455 157 18 0.0422535211267605 1
TGFB2-202 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0030307 Not Cancer Driver No 44 0.1062801932367149 47 5 0.0120772946859903 4
TGFBR1-202 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0030307 Not Cancer Driver No 57 0.1133200795228628 23 3 0.0059642147117296 13
TRIM32-203 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0030307 Not Cancer Driver No 62 0.0949464012251148 87 9 0.0137825421133231 3
UCN-201 UCN P55089 Urocortin chr2 GO:0030307 Not Cancer Driver No 7 0.0564516129032258 61 4 0.032258064516129 0
USP47-203 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0030307 Not Cancer Driver No 86 0.0625454545454545 426 24 0.0174545454545454 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0030307 Not Cancer Driver No 41 0.0813492063492063 491 41 0.0813492063492063 0
ZNF639-209 ZNF639 Q9UID6 Zinc finger protein 639 chr3 GO:0030307 Not Cancer Driver No 42 0.0865979381443299 140 17 0.0350515463917525 0