Total number of protein in "GO:0030307" GO term: 87
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADAM10-201 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0030307 | Not Cancer Driver | No | 73 | 0.0975935828877005 | 156 | 18 | 0.0240641711229946 | 4 |
ADAM17-201 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0030307 | Not Cancer Driver | No | 63 | 0.0764563106796116 | 182 | 17 | 0.020631067961165 | 0 |
AKAP6-201 | AKAP6 | Q13023 | A-kinase anchor protein 6 | chr14 | GO:0030307 | Not Cancer Driver | No | 295 | 0.1272100043122035 | 1464 | 188 | 0.0810694264769297 | 0 |
AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0030307 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
ARMC12-202 | ARMC12 | Q5T9G4 | Armadillo repeat-containing protein 12 | chr6 | GO:0030307 | Not Cancer Driver | No | 40 | 0.1176470588235294 | 8 | 0 | 0.0 | 0 |
AVP-201 | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0030307 | Not Cancer Driver | No | 11 | 0.0670731707317073 | 26 | 1 | 0.0060975609756097 | 26 |
AVPR1A-201 | AVPR1A | P37288 | Vasopressin V1a receptor | chr12 | GO:0030307 | Not Cancer Driver | No | 84 | 0.200956937799043 | 69 | 17 | 0.0406698564593301 | 0 |
BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0030307 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
BRAT1-201 | BRAT1 | Q6PJG6 | BRCA1-associated ATM activator 1 | chr7 | GO:0030307 | Not Cancer Driver | No | 82 | 0.099878197320341 | 102 | 11 | 0.0133982947624847 | 0 |
CD38-201 | CD38 | P28907 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | chr4 | GO:0030307 | Not Cancer Driver | No | 39 | 0.13 | 3 | 0 | 0.0 | 0 |
CDC42-208 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0030307 | Not Cancer Driver | No | 21 | 0.1099476439790576 | 23 | 1 | 0.0052356020942408 | 1 |
CDKN2AIP-203 | CDKN2AIP | Q9NXV6 | CDKN2A-interacting protein | chr4 | GO:0030307 | Not Cancer Driver | No | 18 | 0.0310344827586206 | 352 | 15 | 0.0258620689655172 | 0 |
CEP43-202 | CEP43 | O95684 | Centrosomal protein 43 | chr6 | GO:0030307 | Not Cancer Driver | No | 32 | 0.0802005012531328 | 274 | 27 | 0.0676691729323308 | 0 |
CIB1-201 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0030307 | Not Cancer Driver | No | 16 | 0.0837696335078534 | 6 | 1 | 0.0052356020942408 | 0 |
CSNK2A1-201 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0030307 | Not Cancer Driver | No | 47 | 0.1202046035805626 | 75 | 6 | 0.0153452685421994 | 4 |
CSNK2A3-201 | CSNK2A3 | Q8NEV1 | Casein kinase II subunit alpha 3 | chr11 | GO:0030307 | Not Cancer Driver | No | 47 | 0.1202046035805626 | 76 | 9 | 0.0230179028132992 | 0 |
CXCL16-201 | CXCL16 | Q9H2A7 | C-X-C motif chemokine 16 | chr17 | GO:0030307 | Not Cancer Driver | No | 23 | 0.0905511811023622 | 121 | 12 | 0.0472440944881889 | 0 |
DDX3X-244 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0030307 | Census, Compendium | Yes | 91 | 0.1374622356495468 | 302 | 32 | 0.0483383685800604 | 18 |
DDX49-201 | DDX49 | Q9Y6V7 | Probable ATP-dependent RNA helicase DDX49 | chr19 | GO:0030307 | Not Cancer Driver | No | 35 | 0.072463768115942 | 79 | 4 | 0.0082815734989648 | 0 |
DERL2-201 | DERL2 | Q9GZP9 | Derlin-2 | chr17 | GO:0030307 | Not Cancer Driver | No | 13 | 0.0543933054393305 | 15 | 0 | 0.0 | 0 |
DNPH1-201 | DNPH1 | O43598 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | chr6 | GO:0030307 | Not Cancer Driver | No | 12 | 0.0689655172413793 | 49 | 2 | 0.0114942528735632 | 0 |
EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0030307 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
EIF4G1-202 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | GO:0030307 | Not Cancer Driver | No | 157 | 0.0981863664790494 | 1080 | 103 | 0.0644152595372107 | 2 |
EIF4G2-201 | EIF4G2 | P78344 | Eukaryotic translation initiation factor 4 gamma 2 | chr11 | GO:0030307 | Not Cancer Driver | No | 80 | 0.0882028665931642 | 382 | 38 | 0.041896361631753 | 0 |
ENST00000705256 | CEP43 | O95684 | Centrosomal protein 43 | chr6 | GO:0030307 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
ENST00000695856 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0030307 | Not Cancer Driver | No | 21 | 0.1099476439790576 | 23 | 1 | 0.0052356020942408 | 1 |
ERBB2-201 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0030307 | Census, Compendium | Yes | 249 | 0.198406374501992 | 315 | 32 | 0.0254980079681274 | 1 |
EXOSC2-204 | EXOSC2 | Q13868 | Exosome complex component RRP4 | chr9 | GO:0030307 | Not Cancer Driver | No | 13 | 0.0443686006825938 | 47 | 1 | 0.0034129692832764 | 2 |
EXOSC4-201 | EXOSC4 | Q9NPD3 | Exosome complex component RRP41 | chr8 | GO:0030307 | Not Cancer Driver | No | 26 | 0.1061224489795918 | 23 | 0 | 0.0 | 0 |
EXOSC9-201 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | GO:0030307 | Not Cancer Driver | No | 30 | 0.0683371298405467 | 155 | 11 | 0.0250569476082004 | 1 |
EXTL3-201 | EXTL3 | O43909 | Exostosin-like 3 | chr8 | GO:0030307 | Not Cancer Driver | No | 101 | 0.1099020674646354 | 111 | 17 | 0.0184983677910772 | 5 |
F2-201 | F2 | P00734 | Prothrombin | chr11 | GO:0030307 | Not Cancer Driver | No | 85 | 0.1366559485530546 | 98 | 20 | 0.0321543408360128 | 9 |
FXN-203 | FXN | Q16595 | Frataxin, mitochondrial | chr9 | GO:0030307 | Not Cancer Driver | No | 17 | 0.0809523809523809 | 75 | 1 | 0.0047619047619047 | 8 |
H3-3A-203 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0030307 | Not Cancer Driver | No | 27 | 0.1985294117647058 | 51 | 21 | 0.1544117647058823 | 18 |
H3-3B-201 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0030307 | Not Cancer Driver | No | 26 | 0.1911764705882352 | 51 | 14 | 0.1029411764705882 | 18 |
H3-5-201 | H3-5 | Q6NXT2 | Histone H3.3C | chr12 | GO:0030307 | Not Cancer Driver | No | 27 | 0.2 | 50 | 7 | 0.0518518518518518 | 0 |
HBEGF-201 | HBEGF | Q99075 | Proheparin-binding EGF-like growth factor | chr5 | GO:0030307 | Not Cancer Driver | No | 11 | 0.0528846153846153 | 63 | 2 | 0.0096153846153846 | 0 |
HDGFL2-208 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | GO:0030307 | Not Cancer Driver | No | 26 | 0.0387481371087928 | 622 | 26 | 0.0387481371087928 | 0 |
HPN-210 | HPN | P05981 | Serine protease hepsin | chr19 | GO:0030307 | Not Cancer Driver | No | 49 | 0.1175059952038369 | 12 | 2 | 0.0047961630695443 | 0 |
HYAL1-204 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0030307 | Not Cancer Driver | No | 30 | 0.0689655172413793 | 9 | 0 | 0.0 | 1 |
IGFBP1-201 | IGFBP1 | P08833 | Insulin-like growth factor-binding protein 1 | chr7 | GO:0030307 | Not Cancer Driver | No | 29 | 0.1119691119691119 | 42 | 7 | 0.027027027027027 | 0 |
IL2-201 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0030307 | Census | Yes | 16 | 0.1045751633986928 | 6 | 0 | 0.0 | 0 |
IL9-201 | IL9 | P15248 | Interleukin-9 | chr5 | GO:0030307 | Not Cancer Driver | No | 7 | 0.0486111111111111 | 4 | 0 | 0.0 | 0 |
INO80-209 | INO80 | Q9ULG1 | Chromatin-remodeling ATPase INO80 | chr15 | GO:0030307 | Compendium | Yes | 137 | 0.0880462724935732 | 682 | 67 | 0.0430591259640102 | 0 |
INS-202 | INS | P01308 | Insulin | chr11 | GO:0030307 | Not Cancer Driver | No | 7 | 0.0636363636363636 | 5 | 1 | 0.009090909090909 | 19 |
KDM2B-202 | KDM2B | Q8NHM5 | Lysine-specific demethylase 2B | chr12 | GO:0030307 | Not Cancer Driver | No | 142 | 0.1062874251497006 | 620 | 64 | 0.0479041916167664 | 0 |
KLHL22-201 | KLHL22 | Q53GT1 | Kelch-like protein 22 | chr22 | GO:0030307 | Not Cancer Driver | No | 75 | 0.1182965299684542 | 50 | 7 | 0.0110410094637223 | 0 |
KRT17-201 | KRT17 | Q04695 | Keratin, type I cytoskeletal 17 | chr17 | GO:0030307 | Not Cancer Driver | No | 68 | 0.1574074074074074 | 162 | 28 | 0.0648148148148148 | 13 |
LGI1-202 | LGI1 | O95970 | Leucine-rich glioma-inactivated protein 1 | chr10 | GO:0030307 | Not Cancer Driver | No | 64 | 0.1149012567324955 | 3 | 1 | 0.0017953321364452 | 16 |
MAP2K5-201 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | GO:0030307 | Not Cancer Driver | No | 26 | 0.0580357142857142 | 85 | 6 | 0.0133928571428571 | 0 |
MAPKAP1-201 | MAPKAP1 | Q9BPZ7 | Target of rapamycin complex 2 subunit MAPKAP1 | chr9 | GO:0030307 | Not Cancer Driver | No | 57 | 0.1091954022988505 | 173 | 17 | 0.0325670498084291 | 0 |
MFSD2A-201 | MFSD2A | Q8NA29 | Sodium-dependent lysophosphatidylcholine symporter 1 | chr1 | GO:0030307 | Not Cancer Driver | No | 37 | 0.0681399631675874 | 36 | 3 | 0.005524861878453 | 7 |
MLST8-232 | MLST8 | Q9BVC4 | Target of rapamycin complex subunit LST8 | chr16 | GO:0030307 | Not Cancer Driver | No | 24 | 0.0736196319018405 | 45 | 3 | 0.00920245398773 | 0 |
MMP14-201 | MMP14 | P50281 | Matrix metalloproteinase-14 | chr14 | GO:0030307 | Not Cancer Driver | No | 50 | 0.0859106529209622 | 120 | 6 | 0.0103092783505154 | 1 |
MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0030307 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
MTPN-201 | MTPN | P58546 | Myotrophin | chr7 | GO:0030307 | Not Cancer Driver | No | 7 | 0.059322033898305 | 11 | 3 | 0.0254237288135593 | 0 |
N6AMT1-201 | N6AMT1 | Q9Y5N5 | Methyltransferase N6AMT1 | chr21 | GO:0030307 | Not Cancer Driver | No | 33 | 0.1542056074766355 | 20 | 3 | 0.014018691588785 | 0 |
NCBP1-202 | NCBP1 | Q09161 | Nuclear cap-binding protein subunit 1 | chr9 | GO:0030307 | Not Cancer Driver | No | 66 | 0.0835443037974683 | 89 | 7 | 0.0088607594936708 | 0 |
PABIR1-201 | PABIR1 | Q96E09 | PPP2R1A-PPP2R2A-interacting phosphatase regulator 1 | chr9 | GO:0030307 | Not Cancer Driver | No | 13 | 0.0452961672473867 | 285 | 13 | 0.0452961672473867 | 0 |
PRR5-202 | PRR5 | P85299 | Proline-rich protein 5 | chr22 | GO:0030307 | Not Cancer Driver | No | 41 | 0.1056701030927835 | 177 | 18 | 0.0463917525773195 | 0 |
PRSS2-201 | PRSS2 | P07478 | Trypsin-2 | chr7 | GO:0030307 | Not Cancer Driver | No | 0 | 0.0 | 9 | 0 | 0.0 | 0 |
PSMD10-201 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:0030307 | Not Cancer Driver | No | 13 | 0.0575221238938053 | 53 | 4 | 0.0176991150442477 | 0 |
PTK2B-201 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0030307 | Not Cancer Driver | No | 117 | 0.1159563924677899 | 263 | 23 | 0.0227948463825569 | 0 |
RICTOR-202 | RICTOR | Q6R327 | Rapamycin-insensitive companion of mTOR | chr5 | GO:0030307 | Not Cancer Driver | No | 144 | 0.0843091334894613 | 365 | 34 | 0.0199063231850117 | 0 |
RPS6KA1-204 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | GO:0030307 | Not Cancer Driver | No | 71 | 0.0965986394557823 | 178 | 22 | 0.0299319727891156 | 0 |
RPS6KA3-201 | RPS6KA3 | P51812 | Ribosomal protein S6 kinase alpha-3 | chrX | GO:0030307 | Compendium | Yes | 72 | 0.0972972972972973 | 146 | 10 | 0.0135135135135135 | 13 |
RPTOR-201 | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0030307 | Not Cancer Driver | No | 149 | 0.1116104868913857 | 242 | 18 | 0.0134831460674157 | 0 |
S100A8-202 | S100A8 | P05109 | Protein S100-A8 | chr1 | GO:0030307 | Not Cancer Driver | No | 17 | 0.1827956989247312 | 8 | 4 | 0.043010752688172 | 0 |
S100A9-201 | S100A9 | P06702 | Protein S100-A9 | chr1 | GO:0030307 | Not Cancer Driver | No | 16 | 0.1403508771929824 | 76 | 8 | 0.0701754385964912 | 0 |
SDCBP-201 | SDCBP | O00560 | Syntenin-1 | chr8 | GO:0030307 | Not Cancer Driver | No | 23 | 0.0771812080536912 | 17 | 1 | 0.0033557046979865 | 0 |
SFN-201 | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0030307 | Not Cancer Driver | No | 16 | 0.064516129032258 | 75 | 3 | 0.0120967741935483 | 0 |
SFRP1-201 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0030307 | Not Cancer Driver | No | 31 | 0.0987261146496815 | 39 | 4 | 0.0127388535031847 | 0 |
SFRP2-201 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0030307 | Not Cancer Driver | No | 37 | 0.1254237288135593 | 1 | 0 | 0.0 | 0 |
SLC25A33-201 | SLC25A33 | Q9BSK2 | Solute carrier family 25 member 33 | chr1 | GO:0030307 | Not Cancer Driver | No | 21 | 0.0654205607476635 | 4 | 0 | 0.0 | 0 |
SLC44A4-202 | SLC44A4 | Q53GD3 | Choline transporter-like protein 4 | chr6 | GO:0030307 | Not Cancer Driver | No | 60 | 0.0845070422535211 | 24 | 3 | 0.004225352112676 | 1 |
SLC9A1-201 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0030307 | Not Cancer Driver | No | 57 | 0.0699386503067484 | 252 | 17 | 0.0208588957055214 | 1 |
SPHK1-210 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0030307 | Not Cancer Driver | No | 29 | 0.0755208333333333 | 25 | 0 | 0.0 | 0 |
SUPV3L1-201 | SUPV3L1 | Q8IYB8 | ATP-dependent RNA helicase SUPV3L1, mitochondrial | chr10 | GO:0030307 | Not Cancer Driver | No | 46 | 0.0585241730279898 | 140 | 9 | 0.0114503816793893 | 0 |
TAF9B-201 | TAF9B | Q9HBM6 | Transcription initiation factor TFIID subunit 9B | chrX | GO:0030307 | Not Cancer Driver | No | 30 | 0.1195219123505976 | 189 | 22 | 0.0876494023904382 | 0 |
TEAD1-206 | TEAD1 | P28347 | Transcriptional enhancer factor TEF-1 | chr11 | GO:0030307 | Not Cancer Driver | No | 35 | 0.0821596244131455 | 157 | 18 | 0.0422535211267605 | 1 |
TGFB2-202 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0030307 | Not Cancer Driver | No | 44 | 0.1062801932367149 | 47 | 5 | 0.0120772946859903 | 4 |
TGFBR1-202 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0030307 | Not Cancer Driver | No | 57 | 0.1133200795228628 | 23 | 3 | 0.0059642147117296 | 13 |
TRIM32-203 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0030307 | Not Cancer Driver | No | 62 | 0.0949464012251148 | 87 | 9 | 0.0137825421133231 | 3 |
UCN-201 | UCN | P55089 | Urocortin | chr2 | GO:0030307 | Not Cancer Driver | No | 7 | 0.0564516129032258 | 61 | 4 | 0.032258064516129 | 0 |
USP47-203 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0030307 | Not Cancer Driver | No | 86 | 0.0625454545454545 | 426 | 24 | 0.0174545454545454 | 0 |
YAP1-201 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0030307 | Not Cancer Driver | No | 41 | 0.0813492063492063 | 491 | 41 | 0.0813492063492063 | 0 |
ZNF639-209 | ZNF639 | Q9UID6 | Zinc finger protein 639 | chr3 | GO:0030307 | Not Cancer Driver | No | 42 | 0.0865979381443299 | 140 | 17 | 0.0350515463917525 | 0 |