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Total number of protein in "GO:0030308" GO term:  116

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACVR1B-201 ACVR1B P36896 Activin receptor type-1B chr12 GO:0030308 Census Yes 95 0.1881188118811881 0 0 0.0 0
ACVRL1-201 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0030308 Not Cancer Driver No 80 0.1590457256461232 60 10 0.0198807157057654 64
ADAM15-203 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0030308 Not Cancer Driver No 76 0.0880648899188876 215 23 0.0266512166859791 0
ADIPOR1-201 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0030308 Not Cancer Driver No 48 0.128 70 8 0.0213333333333333 0
AGTR2-201 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0030308 Not Cancer Driver No 67 0.1845730027548209 0 0 0.0 0
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0030308 Census, Compendium Yes 21 0.0878661087866108 73 5 0.0209205020920502 0
BCL6-202 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0030308 Census, Compendium Yes 91 0.1288951841359773 328 45 0.0637393767705382 0
BDKRB1-201 BDKRB1 P46663 B1 bradykinin receptor chr14 GO:0030308 Not Cancer Driver No 47 0.1331444759206798 3 0 0.0 0
BMP10-201 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0030308 Not Cancer Driver No 69 0.1627358490566037 87 10 0.0235849056603773 0
BMPR2-202 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0030308 Compendium Yes 100 0.0963391136801541 601 49 0.0472061657032755 17
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0030308 Census, Compendium Yes 167 0.0896403650026838 1466 127 0.0681696188942565 34
BST2-201 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0030308 Not Cancer Driver No 10 0.0555555555555555 20 0 0.0 0
BTG1-201 BTG1 P62324 Protein BTG1 chr12 GO:0030308 Census, Compendium Yes 22 0.1286549707602339 19 0 0.0 0
CAPRIN2-222 CAPRIN2 Q6IMN6 Caprin-2 chr12 GO:0030308 Not Cancer Driver No 97 0.0860692102928127 764 62 0.0550133096716947 0
CCAR2-201 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0030308 Not Cancer Driver No 83 0.0899241603466955 531 51 0.0552546045503792 0
CCDC85B-201 CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 GO:0030308 Not Cancer Driver No 3 0.0148514851485148 81 2 0.0099009900990099 0
CCN3-201 CCN3 P48745 CCN family member 3 chr8 GO:0030308 Not Cancer Driver No 49 0.1372549019607843 20 2 0.0056022408963585 0
CDA-201 CDA P32320 Cytidine deaminase chr1 GO:0030308 Not Cancer Driver No 15 0.1027397260273972 8 0 0.0 0
CDKN1A-201 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0030308 Census, Compendium Yes 38 0.2317073170731707 121 25 0.1524390243902439 0
CDKN1B-201 CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0030308 Census, Compendium Yes 14 0.0707070707070707 199 14 0.0707070707070707 0
CDKN2A-201 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0030308 Census, Compendium Yes 151 0.967948717948718 83 81 0.5192307692307693 30
CDKN2AIP-203 CDKN2AIP Q9NXV6 CDKN2A-interacting protein chr4 GO:0030308 Not Cancer Driver No 18 0.0310344827586206 352 15 0.0258620689655172 0
CDKN2C-202 CDKN2C P42773 Cyclin-dependent kinase 4 inhibitor C chr1 GO:0030308 Census, Compendium Yes 17 0.1011904761904761 49 5 0.0297619047619047 0
CDKN2D-202 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0030308 Not Cancer Driver No 17 0.1024096385542168 45 3 0.0180722891566265 0
CGRRF1-201 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 GO:0030308 Not Cancer Driver No 20 0.0602409638554216 34 4 0.0120481927710843 0
CRLF3-201 CRLF3 Q8IUI8 Cytokine receptor-like factor 3 chr17 GO:0030308 Not Cancer Driver No 34 0.0769230769230769 80 5 0.0113122171945701 0
CRYAB-217 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0030308 Not Cancer Driver No 17 0.0971428571428571 59 7 0.04 5
CYP27B1-201 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0030308 Not Cancer Driver No 50 0.0984251968503937 79 9 0.0177165354330708 15
DAB2-201 DAB2 P98082 Disabled homolog 2 chr5 GO:0030308 Not Cancer Driver No 108 0.1402597402597402 684 94 0.122077922077922 0
DACT3-202 DACT3 Q96B18 Dapper homolog 3 chr19 GO:0030308 Not Cancer Driver No 11 0.0174880763116057 550 7 0.0111287758346581 0
DCBLD2-201 DCBLD2 Q96PD2 Discoidin, CUB and LCCL domain-containing protein 2 chr3 GO:0030308 Not Cancer Driver No 77 0.0993548387096774 300 29 0.0374193548387096 0
DCSTAMP-201 DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0030308 Compendium Yes 127 0.2702127659574468 6 3 0.0063829787234042 0
DCUN1D3-201 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0030308 Not Cancer Driver No 32 0.1052631578947368 118 9 0.0296052631578947 0
DDX3X-244 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0030308 Census, Compendium Yes 91 0.1374622356495468 302 32 0.0483383685800604 18
DNAJB2-201 DNAJB2 P25686 DnaJ homolog subfamily B member 2 chr2 GO:0030308 Not Cancer Driver No 39 0.1203703703703703 239 31 0.095679012345679 1
EAF2-201 EAF2 Q96CJ1 ELL-associated factor 2 chr3 GO:0030308 Not Cancer Driver No 24 0.0923076923076923 199 18 0.0692307692307692 0
EI24-201 EI24 O14681 Etoposide-induced protein 2.4 homolog chr11 GO:0030308 Not Cancer Driver No 19 0.0558823529411764 12 1 0.0029411764705882 0
ENO1-201 ENO1 P06733 Alpha-enolase chr1 GO:0030308 Not Cancer Driver No 37 0.0852534562211981 21 2 0.0046082949308755 0
ENPP1-204 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0030308 Not Cancer Driver No 114 0.1232432432432432 101 3 0.0032432432432432 32
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 GO:0030308 Not Cancer Driver No 69 0.130188679245283 92 10 0.0188679245283018 1
FBP1-201 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0030308 Not Cancer Driver No 24 0.0710059171597633 19 0 0.0 4
FHL1-205 FHL1 Q13642 Four and a half LIM domains protein 1 chrX GO:0030308 Not Cancer Driver No 40 0.1238390092879257 51 5 0.0154798761609907 10
FRZB-201 FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0030308 Not Cancer Driver No 45 0.1384615384615384 31 5 0.0153846153846153 1
GDF2-201 GDF2 Q9UK05 Growth/differentiation factor 2 chr10 GO:0030308 Not Cancer Driver No 106 0.247086247086247 130 40 0.0932400932400932 3
GDF9-207 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0030308 Not Cancer Driver No 50 0.1101321585903083 54 13 0.0286343612334801 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0030308 Not Cancer Driver No 62 0.1623036649214659 111 20 0.0523560209424083 43
GNG4-203 GNG4 P50150 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 chr1 GO:0030308 Not Cancer Driver No 16 0.2133333333333333 22 1 0.0133333333333333 0
GREM1-203 GREM1 O60565 Gremlin-1 chr15 GO:0030308 Not Cancer Driver No 21 0.1141304347826086 77 9 0.0489130434782608 0
HNF4A-201 HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 GO:0030308 Not Cancer Driver No 113 0.2383966244725738 127 44 0.0928270042194092 5
HRG-201 HRG P04196 Histidine-rich glycoprotein chr3 GO:0030308 Not Cancer Driver No 83 0.1580952380952381 283 57 0.1085714285714285 2
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0030308 Not Cancer Driver No 20 0.0312012480499219 200 10 0.0156006240249609 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0030308 Not Cancer Driver No 19 0.0296411856474258 200 7 0.0109204368174727 0
HYAL1-204 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0030308 Not Cancer Driver No 30 0.0689655172413793 9 0 0.0 1
HYAL2-201 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0030308 Not Cancer Driver No 46 0.0972515856236786 8 1 0.0021141649048625 0
ING1-203 ING1 Q9UK53 Inhibitor of growth protein 1 chr13 GO:0030308 Compendium Yes 55 0.1303317535545023 213 27 0.0639810426540284 3
INHBA-201 INHBA P08476 Inhibin beta A chain chr7 GO:0030308 Not Cancer Driver No 121 0.284037558685446 154 54 0.1267605633802817 0
IP6K2-201 IP6K2 Q9UHH9 Inositol hexakisphosphate kinase 2 chr3 GO:0030308 Not Cancer Driver No 29 0.068075117370892 96 6 0.0140845070422535 0
JADE1-201 JADE1 Q6IE81 Protein Jade-1 chr4 GO:0030308 Not Cancer Driver No 74 0.0878859857482185 410 34 0.0403800475059382 0
MINAR1-201 MINAR1 Q9UPX6 Major intrinsically disordered Notch2-binding receptor 1 chr15 GO:0030308 Not Cancer Driver No 119 0.1299126637554585 589 74 0.0807860262008733 0
MSX1-201 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0030308 Not Cancer Driver No 32 0.1056105610561056 199 12 0.0396039603960396 7
MT3-201 MT3 P25713 Metallothionein-3 chr16 GO:0030308 Not Cancer Driver No 4 0.0588235294117647 0 0 0.0 0
MUL1-201 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0030308 Not Cancer Driver No 29 0.0823863636363636 16 2 0.0056818181818181 0
MYL2-201 MYL2 P10916 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform chr12 GO:0030308 Not Cancer Driver No 32 0.1927710843373494 34 5 0.0301204819277108 6
NAIF1-201 NAIF1 Q69YI7 Nuclear apoptosis-inducing factor 1 chr9 GO:0030308 Not Cancer Driver No 35 0.1070336391437308 219 22 0.0672782874617737 0
NDRG3-201 NDRG3 Q9UGV2 Protein NDRG3 chr20 GO:0030308 Not Cancer Driver No 36 0.096 109 16 0.0426666666666666 0
NDUFA13-204 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0030308 Not Cancer Driver No 27 0.1875 24 6 0.0416666666666666 1
NDUFS3-201 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 GO:0030308 Not Cancer Driver No 22 0.0833333333333333 26 2 0.0075757575757575 2
NME6-209 NME6 O75414 Nucleoside diphosphate kinase 6 chr3 GO:0030308 Not Cancer Driver No 19 0.1021505376344086 22 3 0.0161290322580645 0
NPPB-201 NPPB P16860 Natriuretic peptides B chr1 GO:0030308 Not Cancer Driver No 25 0.1865671641791045 104 22 0.1641791044776119 0
NPR1-202 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0030308 Not Cancer Driver No 105 0.0989632422243166 78 16 0.0150801131008482 0
OSGIN1-203 OSGIN1 Q9UJX0 Oxidative stress-induced growth inhibitor 1 chr16 GO:0030308 Not Cancer Driver No 48 0.10062893081761 82 13 0.0272536687631027 0
OSGIN2-204 OSGIN2 Q9Y236 Oxidative stress-induced growth inhibitor 2 chr8 GO:0030308 Not Cancer Driver No 43 0.0851485148514851 11 0 0.0 0
PHB1-201 PHB1 P35232 Prohibitin 1 chr17 GO:0030308 Not Cancer Driver No 21 0.0772058823529411 4 1 0.0036764705882352 0
PML-201 PML P29590 Protein PML chr15 GO:0030308 Census, Compendium Yes 87 0.0986394557823129 312 28 0.0317460317460317 0
PPP1R9B-202 PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0030308 Not Cancer Driver No 37 0.0452876376988984 698 27 0.033047735618115 0
PPP2CA-203 PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0030308 Not Cancer Driver No 32 0.1035598705501618 12 1 0.0032362459546925 7
PPP2R1A-201 PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0030308 Census, Compendium Yes 169 0.2869269949066214 0 0 0.0 4
PPT1-219 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0030308 Not Cancer Driver No 27 0.088235294117647 0 0 0.0 22
PRDM11-203 PRDM11 Q9NQV5 PR domain-containing protein 11 chr11 GO:0030308 Not Cancer Driver No 66 0.1383647798742138 243 33 0.0691823899371069 0
PSRC1-205 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0030308 Not Cancer Driver No 21 0.0578512396694214 361 21 0.0578512396694214 0
PTPRJ-201 PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0030308 Not Cancer Driver No 130 0.0972326103216155 403 39 0.0291697830964846 0
RACK1-227 RACK1 P63244 Small ribosomal subunit protein RACK1 chr5 GO:0030308 Not Cancer Driver No 27 0.085173501577287 13 0 0.0 0
RB1-201 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0030308 Census, Compendium Yes 89 0.0959051724137931 282 26 0.0280172413793103 21
RBBP7-203 RBBP7 Q16576 Histone-binding protein RBBP7 chrX GO:0030308 Not Cancer Driver No 42 0.0988235294117647 138 8 0.0188235294117647 0
RERG-201 RERG Q96A58 Ras-related and estrogen-regulated growth inhibitor chr12 GO:0030308 Not Cancer Driver No 27 0.135678391959799 39 6 0.0301507537688442 0
RTN4-202 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0030308 Not Cancer Driver No 81 0.0679530201342281 868 50 0.0419463087248322 0
SCGB3A1-201 SCGB3A1 Q96QR1 Secretoglobin family 3A member 1 chr5 GO:0030308 Not Cancer Driver No 3 0.0288461538461538 0 0 0.0 0
SERPINE2-201 SERPINE2 P07093 Glia-derived nexin chr2 GO:0030308 Not Cancer Driver No 55 0.1381909547738693 0 0 0.0 0
SERTAD2-201 SERTAD2 Q14140 SERTA domain-containing protein 2 chr2 GO:0030308 Not Cancer Driver No 30 0.0955414012738853 258 25 0.0796178343949044 0
SERTAD3-201 SERTAD3 Q9UJW9 SERTA domain-containing protein 3 chr19 GO:0030308 Not Cancer Driver No 26 0.1326530612244898 125 15 0.0765306122448979 0
SESN2-201 SESN2 P58004 Sestrin-2 chr1 GO:0030308 Not Cancer Driver No 54 0.1125 147 20 0.0416666666666666 0
SFRP1-201 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0030308 Not Cancer Driver No 31 0.0987261146496815 39 4 0.0127388535031847 0
SFRP2-201 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0030308 Not Cancer Driver No 37 0.1254237288135593 1 0 0.0 0
SH3BP4-202 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0030308 Not Cancer Driver No 114 0.1183800623052959 243 36 0.0373831775700934 0
SIPA1-209 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0030308 Not Cancer Driver No 56 0.0537428023032629 671 41 0.0393474088291746 0
SLIT2-204 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0030308 Not Cancer Driver No 346 0.2262916939175932 31 12 0.0078482668410725 0
SLIT3-205 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0030308 Not Cancer Driver No 292 0.1917268548916612 39 9 0.0059093893630991 0
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0030308 Census, Compendium Yes 80 0.188235294117647 113 15 0.0352941176470588 5
SMAD4-201 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0030308 Census, Compendium Yes 172 0.3115942028985507 195 16 0.0289855072463768 6
SMARCA2-203 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 GO:0030308 Not Cancer Driver No 178 0.1119496855345912 1015 100 0.0628930817610062 36
SMARCA4-201 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0030308 Census, Compendium Yes 300 0.1821493624772313 1078 163 0.0989678202792957 5
SOX17-201 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0030308 Compendium Yes 64 0.1545893719806763 379 45 0.108695652173913 2
SPHK2-201 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0030308 Not Cancer Driver No 71 0.1085626911314984 295 31 0.0474006116207951 0
ST7L-202 ST7L Q8TDW4 Suppressor of tumorigenicity 7 protein-like chr1 GO:0030308 Not Cancer Driver No 39 0.0678260869565217 80 5 0.008695652173913 0
STK11-201 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0030308 Census, Compendium Yes 63 0.1454965357967667 135 12 0.0277136258660508 9
TCHP-202 TCHP Q9BT92 Trichoplein keratin filament-binding protein chr12 GO:0030308 Not Cancer Driver No 37 0.07429718875502 358 33 0.0662650602409638 0
TGFB1-201 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0030308 Not Cancer Driver No 30 0.0769230769230769 44 3 0.0076923076923076 8
TGFB2-202 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0030308 Not Cancer Driver No 44 0.1062801932367149 47 5 0.0120772946859903 4
TMEM196-201 TMEM196 Q5HYL7 Transmembrane protein 196 chr7 GO:0030308 Not Cancer Driver No 27 0.1569767441860465 16 2 0.0116279069767441 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0030308 Census, Compendium Yes 2742 6.977099236641221 282 1364 3.470737913486005 60
TP53TG5-201 TP53TG5 Q9Y2B4 TP53-target gene 5 protein chr20 GO:0030308 Not Cancer Driver No 41 0.1413793103448276 189 17 0.0586206896551724 0
TRIM40-207 TRIM40 Q6P9F5 E3 ubiquitin ligase TRIM40 chr6 GO:0030308 Not Cancer Driver No 33 0.127906976744186 84 7 0.0271317829457364 0
TSPYL2-201 TSPYL2 Q9H2G4 Testis-specific Y-encoded-like protein 2 chrX GO:0030308 Not Cancer Driver No 60 0.0865800865800865 509 42 0.0606060606060606 0
VGLL4-211 VGLL4 Q14135 Transcription cofactor vestigial-like protein 4 chr3 GO:0030308 Not Cancer Driver No 26 0.0878378378378378 250 22 0.0743243243243243 0
WFDC1-201 WFDC1 Q9HC57 WAP four-disulfide core domain protein 1 chr16 GO:0030308 Not Cancer Driver No 13 0.059090909090909 93 2 0.009090909090909 0
WNT11-201 WNT11 O96014 Protein Wnt-11 chr11 GO:0030308 Not Cancer Driver No 37 0.1045197740112994 59 3 0.0084745762711864 0