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Total number of protein in "GO:0030335" GO term:  231

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTG1-205 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0030335 Not Cancer Driver No 67 0.1786666666666666 42 11 0.0293333333333333 15
ACTN4-201 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0030335 Not Cancer Driver No 110 0.1207464324917673 244 36 0.0395170142700329 7
ACVR1-207 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0030335 Census, Compendium Yes 71 0.1394891944990176 21 8 0.0157170923379174 6
ADAM10-201 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0030335 Not Cancer Driver No 73 0.0975935828877005 156 18 0.0240641711229946 4
ADAM17-201 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0030335 Not Cancer Driver No 63 0.0764563106796116 182 17 0.020631067961165 0
ADAM9-209 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0030335 Not Cancer Driver No 59 0.072039072039072 130 7 0.0085470085470085 0
ADRA2A-201 ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0030335 Not Cancer Driver No 46 0.0989247311827957 162 9 0.0193548387096774 0
AIF1-203 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0030335 Not Cancer Driver No 12 0.0816326530612244 61 5 0.0340136054421768 0
AKT2-206 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0030335 Census Yes 57 0.1185031185031185 84 9 0.0187110187110187 2
ANGPTL3-201 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0030335 Not Cancer Driver No 35 0.0760869565217391 154 19 0.0413043478260869 0
APC-201 APC P25054 Adenomatous polyposis coli protein chr5 GO:0030335 Census, Compendium Yes 295 0.1037636299683433 2412 248 0.0872317973971157 22
ARHGEF39-201 ARHGEF39 Q8N4T4 Rho guanine nucleotide exchange factor 39 chr9 GO:0030335 Not Cancer Driver No 28 0.0835820895522388 56 5 0.0149253731343283 0
ATM-229 ATM Q13315 Serine-protein kinase ATM chr11 GO:0030335 Census, Compendium Yes 358 0.1171465968586387 226 29 0.0094895287958115 41
ATP8A1-202 ATP8A1 Q9Y2Q0 Phospholipid-transporting ATPase IA chr4 GO:0030335 Not Cancer Driver No 126 0.1082474226804123 84 7 0.0060137457044673 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0030335 Not Cancer Driver No 88 0.1011494252873563 681 64 0.0735632183908046 0
BMP2-201 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0030335 Not Cancer Driver No 54 0.1363636363636363 140 22 0.0555555555555555 0
CARMIL1-201 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0030335 Not Cancer Driver No 133 0.0970094821298322 540 68 0.049598832968636 0
CARMIL2-201 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0030335 Not Cancer Driver No 111 0.0773519163763066 670 55 0.0383275261324041 4
CASP8-218 CASP8 Q14790 Caspase-8 chr2 GO:0030335 Census, Compendium Yes 116 0.2421711899791231 106 11 0.022964509394572 1
CASS4-205 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0030335 Not Cancer Driver No 160 0.2035623409669211 498 108 0.1374045801526717 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 GO:0030335 Not Cancer Driver No 23 0.1292134831460674 2 0 0.0 0
CBLL1-205 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:0030335 Not Cancer Driver No 56 0.1140529531568228 373 39 0.0794297352342158 0
CCAR1-201 CCAR1 Q8IX12 Cell division cycle and apoptosis regulator protein 1 chr10 GO:0030335 Not Cancer Driver No 69 0.06 772 36 0.0313043478260869 0
CCL11-201 CCL11 P51671 Eotaxin chr17 GO:0030335 Not Cancer Driver No 15 0.1546391752577319 14 3 0.0309278350515463 0
CCL24-201 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0030335 Not Cancer Driver No 18 0.1512605042016806 23 3 0.0252100840336134 0
CCL26-201 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0030335 Not Cancer Driver No 6 0.0638297872340425 0 0 0.0 0
CCL3-204 CCL3 P10147 C-C motif chemokine 3 chr17 GO:0030335 Not Cancer Driver No 13 0.1413043478260869 0 0 0.0 0
CCL5-201 CCL5 P13501 C-C motif chemokine 5 chr17 GO:0030335 Not Cancer Driver No 7 0.0769230769230769 0 0 0.0 0
CCL7-201 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0030335 Not Cancer Driver No 20 0.202020202020202 13 3 0.0303030303030303 0
CCN1-201 CCN1 O00622 CCN family member 1 chr1 GO:0030335 Not Cancer Driver No 29 0.0761154855643044 12 0 0.0 0
CCR1-201 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0030335 Not Cancer Driver No 47 0.1323943661971831 14 0 0.0 0
CD151-202 CD151 P48509 CD151 antigen chr11 GO:0030335 Not Cancer Driver No 17 0.067193675889328 4 0 0.0 0
CD274-202 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0030335 Census Yes 26 0.0896551724137931 54 9 0.0310344827586206 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0030335 Not Cancer Driver No 21 0.1099476439790576 23 1 0.0052356020942408 1
CDH13-209 CDH13 P55290 Cadherin-13 chr16 GO:0030335 Not Cancer Driver No 128 0.1795231416549789 236 47 0.0659186535764375 0
CDH5-201 CDH5 P33151 Cadherin-5 chr16 GO:0030335 Not Cancer Driver No 121 0.1543367346938775 305 44 0.0561224489795918 0
CEACAM6-201 CEACAM6 P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 chr19 GO:0030335 Not Cancer Driver No 40 0.1162790697674418 110 11 0.0319767441860465 0
CEMIP-203 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0030335 Not Cancer Driver No 149 0.1094783247612049 106 6 0.0044085231447465 0
CEP43-202 CEP43 O95684 Centrosomal protein 43 chr6 GO:0030335 Not Cancer Driver No 32 0.0802005012531328 274 27 0.0676691729323308 0
CGA-204 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0030335 Not Cancer Driver No 24 0.2068965517241379 0 0 0.0 0
CIB1-201 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0030335 Not Cancer Driver No 16 0.0837696335078534 6 1 0.0052356020942408 0
CLDN1-201 CLDN1 O95832 Claudin-1 chr3 GO:0030335 Not Cancer Driver No 19 0.0900473933649289 16 0 0.0 0
CLDN3-201 CLDN3 O15551 Claudin-3 chr7 GO:0030335 Not Cancer Driver No 12 0.0545454545454545 0 0 0.0 0
CLDN4-201 CLDN4 O14493 Claudin-4 chr7 GO:0030335 Not Cancer Driver No 34 0.1626794258373205 0 0 0.0 0
CLEC7A-202 CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0030335 Not Cancer Driver No 31 0.1255060728744939 46 1 0.0040485829959514 0
COL1A1-201 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0030335 Census, Compendium Yes 36 0.0245901639344262 1213 10 0.0068306010928961 140
CPNE3-203 CPNE3 O75131 Copine-3 chr8 GO:0030335 Not Cancer Driver No 56 0.1042830540037244 34 4 0.0074487895716946 0
CSF1-201 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0030335 Not Cancer Driver No 56 0.1010830324909747 342 38 0.0685920577617328 0
CSF1R-210 CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0030335 Census Yes 101 0.1039094650205761 124 12 0.0123456790123456 20
CSF2-201 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0030335 Not Cancer Driver No 8 0.0555555555555555 34 3 0.0208333333333333 0
CTSH-201 CTSH P09668 Pro-cathepsin H chr15 GO:0030335 Not Cancer Driver No 35 0.1044776119402985 4 0 0.0 0
CXCL12-203 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0030335 Not Cancer Driver No 8 0.086021505376344 0 0 0.0 0
CXCL16-201 CXCL16 Q9H2A7 C-X-C motif chemokine 16 chr17 GO:0030335 Not Cancer Driver No 23 0.0905511811023622 121 12 0.0472440944881889 0
CXCR4-201 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0030335 Census, Compendium Yes 45 0.1278409090909091 5 0 0.0 0
DAAM2-201 DAAM2 Q86T65 Disheveled-associated activator of morphogenesis 2 chr6 GO:0030335 Not Cancer Driver No 146 0.1367041198501872 273 47 0.0440074906367041 0
DAB2-201 DAB2 P98082 Disabled homolog 2 chr5 GO:0030335 Not Cancer Driver No 108 0.1402597402597402 684 94 0.122077922077922 0
DAPK3-202 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0030335 Not Cancer Driver No 45 0.0991189427312775 82 6 0.013215859030837 0
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0030335 Not Cancer Driver No 26 0.0828025477707006 181 19 0.0605095541401273 0
DRD1-201 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0030335 Not Cancer Driver No 49 0.1098654708520179 30 3 0.0067264573991031 0
EDN1-201 EDN1 P05305 Endothelin-1 chr6 GO:0030335 Not Cancer Driver No 27 0.1273584905660377 98 16 0.0754716981132075 3
EGF-201 EGF P01133 Pro-epidermal growth factor chr4 GO:0030335 Not Cancer Driver No 149 0.1234465617232808 193 22 0.0182270091135045 1
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 GO:0030335 Census, Compendium Yes 346 0.2859504132231405 223 30 0.024793388429752 1
ELP3-201 ELP3 Q9H9T3 Elongator complex protein 3 chr8 GO:0030335 Not Cancer Driver No 41 0.0749542961608775 19 2 0.0036563071297989 0
ELP5-204 ELP5 Q8TE02 Elongator complex protein 5 chr17 GO:0030335 Not Cancer Driver No 24 0.08 118 8 0.0266666666666666 0
ELP6-201 ELP6 Q0PNE2 Elongator complex protein 6 chr3 GO:0030335 Not Cancer Driver No 23 0.0864661654135338 3 0 0.0 0
ENST00000705256 CEP43 O95684 Centrosomal protein 43 chr6 GO:0030335 Not Cancer Driver No 0 0.0 0 0 0.0 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0030335 Not Cancer Driver No 21 0.1099476439790576 23 1 0.0052356020942408 1
EPHA1-201 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0030335 Not Cancer Driver No 109 0.1116803278688524 211 29 0.0297131147540983 0
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0030335 Compendium Yes 147 0.1506147540983606 188 33 0.033811475409836 3
EPHA4-201 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0030335 Not Cancer Driver No 132 0.1338742393509127 141 16 0.0162271805273833 0
EPHB2-204 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0030335 Not Cancer Driver No 149 0.1412322274881516 120 11 0.0104265402843601 7
F10-202 F10 P00742 Coagulation factor X chr13 GO:0030335 Not Cancer Driver No 73 0.1495901639344262 121 22 0.0450819672131147 25
F2R-201 F2R P25116 Proteinase-activated receptor 1 chr5 GO:0030335 Not Cancer Driver No 55 0.1294117647058823 19 2 0.0047058823529411 0
F2RL1-201 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0030335 Not Cancer Driver No 33 0.0831234256926952 7 0 0.0 0
F3-201 F3 P13726 Tissue factor chr1 GO:0030335 Not Cancer Driver No 18 0.0610169491525423 61 4 0.0135593220338983 0
F7-202 F7 P08709 Coagulation factor VII chr13 GO:0030335 Not Cancer Driver No 56 0.1201716738197424 51 7 0.0150214592274678 88
FAM107A-201 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0030335 Not Cancer Driver No 19 0.1319444444444444 140 18 0.125 0
FAM110C-201 FAM110C Q1W6H9 Protein FAM110C chr2 GO:0030335 Not Cancer Driver No 22 0.0685358255451713 286 22 0.0685358255451713 0
FAM83H-201 FAM83H Q6ZRV2 Protein FAM83H chr8 GO:0030335 Not Cancer Driver No 125 0.106022052586938 898 76 0.0644614079728583 1
FAM89B-203 FAM89B Q8N5H3 Leucine repeat adapter protein 25 chr11 GO:0030335 Not Cancer Driver No 12 0.0634920634920634 109 10 0.0529100529100529 0
FER-201 FER P16591 Tyrosine-protein kinase Fer chr5 GO:0030335 Not Cancer Driver No 70 0.0851581508515815 145 13 0.0158150851581508 0
FERMT2-201 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0030335 Not Cancer Driver No 44 0.0647058823529411 102 8 0.0117647058823529 0
FERMT3-201 FERMT3 Q86UX7 Fermitin family homolog 3 chr11 GO:0030335 Not Cancer Driver No 75 0.1124437781109445 108 13 0.0194902548725637 0
FGF1-201 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0030335 Not Cancer Driver No 21 0.1354838709677419 29 2 0.0129032258064516 0
FGR-203 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0030335 Not Cancer Driver No 67 0.1266540642722117 52 6 0.0113421550094517 0
FLT1-201 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0030335 Not Cancer Driver No 212 0.1584454409566517 103 17 0.0127055306427503 0
FLT4-201 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0030335 Census, Compendium Yes 203 0.1489361702127659 259 33 0.0242112986060161 14
FOXF1-201 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0030335 Not Cancer Driver No 43 0.1134564643799472 196 16 0.0422163588390501 16
FSHB-203 FSHB P01225 Follitropin subunit beta chr11 GO:0030335 Not Cancer Driver No 31 0.2403100775193798 0 0 0.0 1
FZD4-201 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0030335 Not Cancer Driver No 40 0.074487895716946 33 5 0.0093109869646182 17
GCNT2-216 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0030335 Not Cancer Driver No 27 0.0671641791044776 3 0 0.0 0
GNAI2-202 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0030335 Compendium Yes 37 0.104225352112676 24 0 0.0 0
GPER1-202 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0030335 Not Cancer Driver No 47 0.1253333333333333 13 4 0.0106666666666666 0
GPNMB-202 GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:0030335 Not Cancer Driver No 72 0.1258741258741259 95 13 0.0227272727272727 0
GRB7-201 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 GO:0030335 Not Cancer Driver No 61 0.1146616541353383 134 18 0.0338345864661654 0
GRN-201 GRN P28799 Progranulin chr17 GO:0030335 Not Cancer Driver No 64 0.1079258010118043 29 4 0.0067453625632377 1
HAS2-201 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0030335 Not Cancer Driver No 74 0.1340579710144927 17 1 0.0018115942028985 0
HBEGF-201 HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0030335 Not Cancer Driver No 11 0.0528846153846153 63 2 0.0096153846153846 0
HGF-201 HGF P14210 Hepatocyte growth factor chr7 GO:0030335 Compendium Yes 196 0.2692307692307692 43 16 0.0219780219780219 0
HRAS-201 HRAS P01112 GTPase HRas chr11 GO:0030335 Census, Compendium Yes 129 0.6825396825396826 16 2 0.0105820105820105 10
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0030335 Not Cancer Driver No 49 0.0749235474006116 282 26 0.0397553516819571 0
IGF1-201 IGF1 P05019 Insulin-like growth factor I chr12 GO:0030335 Not Cancer Driver No 30 0.1538461538461538 87 18 0.0923076923076923 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0030335 Not Cancer Driver No 143 0.1046086320409656 265 30 0.021945866861741 6
IL1B-201 IL1B P01584 Interleukin-1 beta chr2 GO:0030335 Not Cancer Driver No 32 0.1189591078066914 16 2 0.0074349442379182 0
IL4-201 IL4 P05112 Interleukin-4 chr5 GO:0030335 Not Cancer Driver No 6 0.0392156862745098 0 0 0.0 0
INS-202 INS P01308 Insulin chr11 GO:0030335 Not Cancer Driver No 7 0.0636363636363636 5 1 0.009090909090909 19
INSM1-201 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0030335 Not Cancer Driver No 23 0.0450980392156862 360 11 0.0215686274509803 0
INSR-201 INSR P06213 Insulin receptor chr19 GO:0030335 Not Cancer Driver No 139 0.1005788712011577 282 37 0.0267727930535455 63
ITGA5-201 ITGA5 P08648 Integrin alpha-5 chr12 GO:0030335 Not Cancer Driver No 89 0.0848427073403241 202 21 0.0200190657769304 0
ITGA6-206 ITGA6 P23229 Integrin alpha-6 chr2 GO:0030335 Not Cancer Driver No 88 0.0778761061946902 226 20 0.0176991150442477 0
ITGAV-201 ITGAV P06756 Integrin alpha-V chr2 GO:0030335 Census Yes 100 0.0954198473282442 92 8 0.0076335877862595 0
ITGAX-201 ITGAX P20702 Integrin alpha-X chr16 GO:0030335 Not Cancer Driver No 198 0.1702493551160791 83 13 0.0111779879621668 0
ITGB1-201 ITGB1 P05556 Integrin beta-1 chr10 GO:0030335 Not Cancer Driver No 73 0.0914786967418546 84 8 0.0100250626566416 0
JAK2-201 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0030335 Census, Compendium Yes 81 0.0715547703180212 59 4 0.0035335689045936 4
KDR-201 KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0030335 Census, Compendium Yes 276 0.2035398230088495 276 40 0.0294985250737463 2
KIT-201 KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0030335 Census, Compendium Yes 186 0.1905737704918032 84 24 0.0245901639344262 15
LAMB1-201 LAMB1 P07942 Laminin subunit beta-1 chr7 GO:0030335 Not Cancer Driver No 198 0.1108622620380739 423 42 0.0235162374020156 0
LAMC2-201 LAMC2 Q13753 Laminin subunit gamma-2 chr1 GO:0030335 Not Cancer Driver No 125 0.104777870913663 498 51 0.0427493713327745 0
LEF1-201 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0030335 Census Yes 51 0.1278195488721804 372 47 0.1177944862155388 0
LGR6-203 LGR6 Q9HBX8 Leucine-rich repeat-containing G-protein coupled receptor 6 chr1 GO:0030335 Not Cancer Driver No 126 0.1302998965873836 101 8 0.0082730093071354 0
LRRC15-201 LRRC15 Q8TF66 Leucine-rich repeat-containing protein 15 chr3 GO:0030335 Not Cancer Driver No 97 0.1669535283993115 38 10 0.0172117039586919 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0030335 Census Yes 78 0.15234375 85 10 0.01953125 0
MAP4K4-202 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0030335 Not Cancer Driver No 60 0.0484261501210653 648 29 0.0234059725585149 0
MAZ-202 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0030335 Not Cancer Driver No 34 0.0712788259958071 250 16 0.0335429769392033 0
MCAM-201 MCAM P43121 Cell surface glycoprotein MUC18 chr11 GO:0030335 Not Cancer Driver No 63 0.0975232198142414 310 29 0.044891640866873 0
MDK-203 MDK P21741 Midkine chr11 GO:0030335 Not Cancer Driver No 13 0.0909090909090909 20 1 0.0069930069930069 0
MGAT5-201 MGAT5 Q09328 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A chr2 GO:0030335 Not Cancer Driver No 81 0.1093117408906882 24 2 0.0026990553306342 0
MIEN1-201 MIEN1 Q9BRT3 Migration and invasion enhancer 1 chr17 GO:0030335 Not Cancer Driver No 15 0.1304347826086956 37 4 0.0347826086956521 0
MMP14-201 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0030335 Not Cancer Driver No 50 0.0859106529209622 120 6 0.0103092783505154 1
MMP2-201 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0030335 Not Cancer Driver No 101 0.153030303030303 29 5 0.0075757575757575 2
MMP7-201 MMP7 P09237 Matrilysin chr11 GO:0030335 Not Cancer Driver No 27 0.1011235955056179 70 2 0.0074906367041198 0
MYADM-204 MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0030335 Not Cancer Driver No 50 0.15527950310559 0 0 0.0 0
MYLK-202 MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 GO:0030335 Not Cancer Driver No 267 0.1394984326018808 965 144 0.0752351097178683 3
MYO1C-220 MYO1C O00159 Unconventional myosin-Ic chr17 GO:0030335 Not Cancer Driver No 86 0.0809031044214487 66 9 0.0084666039510818 0
MYOC-201 MYOC Q99972 Myocilin chr1 GO:0030335 Not Cancer Driver No 76 0.1507936507936507 197 36 0.0714285714285714 49
NEDD9-202 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0030335 Not Cancer Driver No 80 0.0959232613908872 520 55 0.065947242206235 0
NOTCH1-204 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0030335 Census, Compendium Yes 312 0.1221135029354207 690 71 0.0277886497064579 3
NTF3-201 NTF3 P20783 Neurotrophin-3 chr12 GO:0030335 Not Cancer Driver No 49 0.1906614785992217 102 23 0.0894941634241245 0
NTRK3-217 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0030335 Census, Compendium Yes 214 0.2550655542312277 56 15 0.0178784266984505 3
NUMB-213 NUMB P49757 Protein numb homolog chr14 GO:0030335 Not Cancer Driver No 50 0.0768049155145929 489 42 0.064516129032258 0
ONECUT1-201 ONECUT1 Q9UBC0 Hepatocyte nuclear factor 6 chr15 GO:0030335 Not Cancer Driver No 57 0.1225806451612903 409 47 0.1010752688172043 0
PAK1-202 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0030335 Not Cancer Driver No 36 0.0660550458715596 300 19 0.0348623853211009 2
PDCD10-201 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0030335 Not Cancer Driver No 25 0.1179245283018868 25 3 0.0141509433962264 0
PDGFA-201 PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0030335 Not Cancer Driver No 26 0.1232227488151658 75 10 0.0473933649289099 0
PDGFB-201 PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0030335 Census Yes 30 0.1244813278008298 99 16 0.0663900414937759 2
PDGFC-203 PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0030335 Not Cancer Driver No 63 0.1826086956521739 53 6 0.017391304347826 0
PDGFD-202 PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0030335 Not Cancer Driver No 72 0.1945945945945946 38 14 0.0378378378378378 0
PDGFRA-201 PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0030335 Census, Compendium Yes 213 0.1955922865013774 173 36 0.0330578512396694 2
PDGFRB-201 PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0030335 Census, Compendium Yes 134 0.1211573236889692 233 40 0.0361663652802893 7
PDPN-211 PDPN Q86YL7 Podoplanin chr1 GO:0030335 Not Cancer Driver No 30 0.1851851851851851 97 21 0.1296296296296296 0
PECAM1-203 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 GO:0030335 Not Cancer Driver No 0 0.0 153 0 0.0 0
PIK3CD-202 PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0030335 Not Cancer Driver No 116 0.1111111111111111 61 8 0.0076628352490421 1
PIK3R3-201 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0030335 Not Cancer Driver No 42 0.0911062906724512 149 17 0.0368763557483731 0
PLAU-201 PLAU P00749 Urokinase-type plasminogen activator chr10 GO:0030335 Not Cancer Driver No 51 0.1183294663573085 10 0 0.0 0
PLET1-201 PLET1 Q6UQ28 Placenta-expressed transcript 1 protein chr11 GO:0030335 Not Cancer Driver No 5 0.0241545893719806 0 0 0.0 0
PLP1-223 PLP1 P60201 Myelin proteolipid protein chrX GO:0030335 Not Cancer Driver No 36 0.1299638989169675 5 0 0.0 64
PODXL-202 PODXL O00592 Podocalyxin chr7 GO:0030335 Not Cancer Driver No 49 0.0878136200716845 435 41 0.0734767025089605 0
PPM1F-201 PPM1F P49593 Protein phosphatase 1F chr22 GO:0030335 Not Cancer Driver No 46 0.1013215859030837 243 24 0.052863436123348 0
PPP3CA-203 PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0030335 Compendium Yes 63 0.1209213051823416 140 24 0.0460652591170825 7
PREX1-201 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0030335 Not Cancer Driver No 232 0.1398432790837854 310 48 0.0289330922242314 0
PRKCA-202 PRKCA P17252 Protein kinase C alpha type chr17 GO:0030335 Not Cancer Driver No 70 0.1041666666666666 155 17 0.025297619047619 0
PTK2-228 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0030335 Not Cancer Driver No 102 0.0969581749049429 426 45 0.0427756653992395 0
PTK2B-201 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0030335 Not Cancer Driver No 117 0.1159563924677899 263 23 0.0227948463825569 0
PTP4A1-203 PTP4A1 Q93096 Protein tyrosine phosphatase type IVA 1 chr6 GO:0030335 Not Cancer Driver No 11 0.0635838150289017 2 0 0.0 0
RACK1-227 RACK1 P63244 Small ribosomal subunit protein RACK1 chr5 GO:0030335 Not Cancer Driver No 27 0.085173501577287 13 0 0.0 0
RDX-219 RDX P35241 Radixin chr11 GO:0030335 Not Cancer Driver No 44 0.0754716981132075 298 23 0.039451114922813 1
RET-202 RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0030335 Census, Compendium Yes 176 0.1579892280071813 108 11 0.0098743267504488 91
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0030335 Not Cancer Driver No 23 0.1191709844559585 53 4 0.0207253886010362 0
RHOD-201 RHOD O00212 Rho-related GTP-binding protein RhoD chr11 GO:0030335 Not Cancer Driver No 16 0.0761904761904762 10 0 0.0 0
RIPOR1-202 RIPOR1 Q6ZS17 Rho family-interacting cell polarization regulator 1 chr16 GO:0030335 Not Cancer Driver No 82 0.0670482420278004 687 47 0.0384300899427636 0
ROCK2-202 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0030335 Not Cancer Driver No 110 0.0792507204610951 734 61 0.0439481268011527 0
ROR2-201 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0030335 Not Cancer Driver No 164 0.1739130434782608 304 58 0.0615058324496288 5
RUFY3-201 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0030335 Not Cancer Driver No 56 0.1194029850746268 204 21 0.044776119402985 0
S1PR1-201 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0030335 Not Cancer Driver No 69 0.1806282722513089 29 5 0.013089005235602 0
SDCBP-201 SDCBP O00560 Syntenin-1 chr8 GO:0030335 Not Cancer Driver No 23 0.0771812080536912 17 1 0.0033557046979865 0
SEMA3B-212 SEMA3B Q13214 Semaphorin-3B chr3 GO:0030335 Not Cancer Driver No 0 0.0 145 0 0.0 0
SEMA3C-201 SEMA3C Q99985 Semaphorin-3C chr7 GO:0030335 Not Cancer Driver No 102 0.1358189081225033 112 17 0.0226364846870838 0
SEMA3D-201 SEMA3D O95025 Semaphorin-3D chr7 GO:0030335 Not Cancer Driver No 160 0.2059202059202059 101 36 0.0463320463320463 0
SEMA3E-204 SEMA3E O15041 Semaphorin-3E chr7 GO:0030335 Not Cancer Driver No 162 0.2090322580645161 87 24 0.0309677419354838 0
SEMA3F-201 SEMA3F Q13275 Semaphorin-3F chr3 GO:0030335 Not Cancer Driver No 86 0.1095541401273885 195 25 0.0318471337579617 0
SEMA3G-201 SEMA3G Q9NS98 Semaphorin-3G chr3 GO:0030335 Not Cancer Driver No 82 0.1048593350383631 206 27 0.0345268542199488 0
SEMA4A-204 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0030335 Not Cancer Driver No 101 0.1327201051248357 122 17 0.0223390275952693 4
SEMA4B-202 SEMA4B Q9NPR2 Semaphorin-4B chr15 GO:0030335 Not Cancer Driver No 73 0.087216248506571 107 14 0.016726403823178 0
SEMA4C-201 SEMA4C Q9C0C4 Semaphorin-4C chr2 GO:0030335 Not Cancer Driver No 81 0.0972388955582232 149 15 0.0180072028811524 0
SEMA4D-208 SEMA4D Q92854 Semaphorin-4D chr9 GO:0030335 Not Cancer Driver No 93 0.1078886310904872 132 14 0.0162412993039443 0
SEMA4F-202 SEMA4F O95754 Semaphorin-4F chr2 GO:0030335 Not Cancer Driver No 90 0.1168831168831168 140 12 0.0155844155844155 0
SEMA4G-210 SEMA4G Q9NTN9 Semaphorin-4G chr10 GO:0030335 Not Cancer Driver No 0 0.0 0 0 0.0 0
SEMA5A-201 SEMA5A Q13591 Semaphorin-5A chr5 GO:0030335 Not Cancer Driver No 221 0.2057728119180633 24 2 0.0018621973929236 0
SEMA5B-202 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0030335 Not Cancer Driver No 198 0.1720243266724587 163 16 0.0139009556907037 0
SEMA6B-201 SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0030335 Not Cancer Driver No 66 0.0743243243243243 340 17 0.0191441441441441 0
SEMA6C-204 SEMA6C Q9H3T2 Semaphorin-6C chr1 GO:0030335 Not Cancer Driver No 93 0.1 413 22 0.0236559139784946 0
SEMA6D-207 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0030335 Not Cancer Driver No 162 0.1509785647716682 476 75 0.0698974836905871 0
SEMA7A-201 SEMA7A O75326 Semaphorin-7A chr15 GO:0030335 Not Cancer Driver No 64 0.0960960960960961 150 19 0.0285285285285285 1
SERPINB3-201 SERPINB3 P29508 Serpin B3 chr18 GO:0030335 Not Cancer Driver No 116 0.2974358974358974 47 23 0.0589743589743589 0
SH3RF2-201 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:0030335 Not Cancer Driver No 125 0.1714677640603566 460 80 0.1097393689986282 0
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0030335 Census, Compendium Yes 80 0.188235294117647 113 15 0.0352941176470588 5
SMIM22-209 SMIM22 K7EJ46 Small integral membrane protein 22 chr16 GO:0030335 Not Cancer Driver No 1 0.0120481927710843 20 1 0.0120481927710843 0
SMO-201 SMO Q99835 Protein smoothened chr7 GO:0030335 Census, Compendium Yes 88 0.1118170266836086 242 20 0.025412960609911 1
SNAI1-201 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0030335 Not Cancer Driver No 41 0.1553030303030303 98 8 0.0303030303030303 0
SNAI2-201 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0030335 Not Cancer Driver No 43 0.1604477611940298 52 8 0.0298507462686567 0
SOD2-210 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0030335 Not Cancer Driver No 21 0.0945945945945946 25 3 0.0135135135135135 0
SPAG9-201 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 GO:0030335 Not Cancer Driver No 95 0.0719152157456472 844 62 0.0469341408024224 0
SPHK1-210 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0030335 Not Cancer Driver No 29 0.0755208333333333 25 0 0.0 0
SPRY2-202 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0030335 Not Cancer Driver No 32 0.1015873015873015 170 19 0.0603174603174603 1
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0030335 Census, Compendium Yes 93 0.1207792207792207 152 16 0.0207792207792207 15
STX4-201 STX4 Q12846 Syntaxin-4 chr16 GO:0030335 Not Cancer Driver No 39 0.1313131313131313 153 16 0.0538720538720538 0
SUN2-218 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 GO:0030335 Not Cancer Driver No 49 0.0683403068340306 214 13 0.0181311018131101 0
SYNE2-202 SYNE2 Q8WXH0 Nesprin-2 chr14 GO:0030335 Not Cancer Driver No 580 0.0842411038489469 1900 180 0.0261437908496732 1
TCAF2-208 TCAF2 A6NFQ2 TRPM8 channel-associated factor 2 chr7 GO:0030335 Not Cancer Driver No 36 0.0391730141458106 38 7 0.0076169749727965 0
TDGF1-201 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0030335 Not Cancer Driver No 34 0.1808510638297872 25 2 0.0106382978723404 0
TGFB1-201 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0030335 Not Cancer Driver No 30 0.0769230769230769 44 3 0.0076923076923076 8
TGFBR1-202 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0030335 Not Cancer Driver No 57 0.1133200795228628 23 3 0.0059642147117296 13
THBS1-201 THBS1 P07996 Thrombospondin-1 chr15 GO:0030335 Not Cancer Driver No 153 0.1307692307692307 321 50 0.0427350427350427 0
TIAM1-206 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0030335 Not Cancer Driver No 263 0.1653048397234443 813 147 0.092394720301697 0
TJP1-201 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0030335 Not Cancer Driver No 143 0.0818077803203661 1350 113 0.0646453089244851 0
TNFAIP6-201 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:0030335 Not Cancer Driver No 48 0.1732851985559566 13 5 0.0180505415162454 0
TRADD-201 TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 GO:0030335 Not Cancer Driver No 18 0.0576923076923076 74 4 0.0128205128205128 0
TRIM32-203 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0030335 Not Cancer Driver No 62 0.0949464012251148 87 9 0.0137825421133231 3
TRIP6-201 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 GO:0030335 Not Cancer Driver No 48 0.1008403361344537 270 14 0.0294117647058823 0
TWIST1-201 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0030335 Not Cancer Driver No 21 0.1039603960396039 132 9 0.0445544554455445 6
TWIST2-202 TWIST2 Q8WVJ9 Twist-related protein 2 chr2 GO:0030335 Not Cancer Driver No 9 0.05625 90 2 0.0125 3
UBE2I-203 UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:0030335 Not Cancer Driver No 16 0.1012658227848101 16 3 0.0189873417721519 0
VEGFA-226 VEGFA P15692 Vascular endothelial growth factor A, long form chr6 GO:0030335 Not Cancer Driver No 24 0.060759493670886 215 9 0.0227848101265822 0
VIL1-201 VIL1 P09327 Villin-1 chr2 GO:0030335 Not Cancer Driver No 90 0.1088270858524788 222 26 0.0314389359129383 0
VSIR-201 VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0030335 Not Cancer Driver No 41 0.1318327974276527 135 15 0.0482315112540192 0
WASHC1-203 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0030335 Not Cancer Driver No 0 0.0 340 0 0.0 0
WNT5B-202 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0030335 Not Cancer Driver No 55 0.1532033426183844 23 4 0.011142061281337 0
XBP1-201 XBP1 P17861 X-box-binding protein 1 chr22 GO:0030335 Not Cancer Driver No 11 0.0421455938697318 171 6 0.0229885057471264 0
ZNF268-205 ZNF268 Q14587 Zinc finger protein 268 chr12 GO:0030335 Not Cancer Driver No 55 0.058078141499472 63 5 0.0052798310454065 0
ZNF304-201 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0030335 Not Cancer Driver No 78 0.1183611532625189 54 8 0.0121396054628224 0
ZNF703-201 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0030335 Not Cancer Driver No 23 0.0389830508474576 415 14 0.023728813559322 0