Total number of protein in "GO:0030509" GO term: 76
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0030509 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| ACVR1-207 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0030509 | Census, Compendium | Yes | 71 | 0.1394891944990176 | 21 | 8 | 0.0157170923379174 | 6 |
| ACVR2A-201 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:0030509 | Census, Compendium | Yes | 64 | 0.124756335282651 | 56 | 4 | 0.0077972709551656 | 0 |
| ACVR2B-201 | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0030509 | Not Cancer Driver | No | 55 | 0.107421875 | 70 | 11 | 0.021484375 | 2 |
| ACVRL1-201 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0030509 | Not Cancer Driver | No | 80 | 0.1590457256461232 | 60 | 10 | 0.0198807157057654 | 64 |
| AMHR2-201 | AMHR2 | Q16671 | Anti-Muellerian hormone type-2 receptor | chr12 | GO:0030509 | Not Cancer Driver | No | 67 | 0.1169284467713787 | 118 | 9 | 0.0157068062827225 | 8 |
| ATF2-201 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0030509 | Not Cancer Driver | No | 42 | 0.0831683168316831 | 451 | 36 | 0.0712871287128712 | 0 |
| BMP10-201 | BMP10 | O95393 | Bone morphogenetic protein 10 | chr2 | GO:0030509 | Not Cancer Driver | No | 69 | 0.1627358490566037 | 87 | 10 | 0.0235849056603773 | 0 |
| BMP2-201 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0030509 | Not Cancer Driver | No | 54 | 0.1363636363636363 | 140 | 22 | 0.0555555555555555 | 0 |
| BMP4-201 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0030509 | Not Cancer Driver | No | 69 | 0.1691176470588235 | 142 | 20 | 0.0490196078431372 | 5 |
| BMP5-201 | BMP5 | P22003 | Bone morphogenetic protein 5 | chr6 | GO:0030509 | Census | Yes | 127 | 0.2797356828193832 | 112 | 45 | 0.0991189427312775 | 0 |
| BMP6-201 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0030509 | Not Cancer Driver | No | 79 | 0.1539961013645224 | 228 | 41 | 0.0799220272904483 | 6 |
| BMP7-201 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0030509 | Not Cancer Driver | No | 68 | 0.1577726218097447 | 69 | 13 | 0.0301624129930394 | 0 |
| BMPER-221 | BMPER | Q8N8U9 | BMP-binding endothelial regulator protein | chr7 | GO:0030509 | Not Cancer Driver | No | 144 | 0.2102189781021897 | 0 | 0 | 0.0 | 1 |
| BMPR1A-201 | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0030509 | Census, Compendium | Yes | 37 | 0.0695488721804511 | 21 | 0 | 0.0 | 8 |
| BMPR1B-208 | BMPR1B | O00238 | Bone morphogenetic protein receptor type-1B | chr4 | GO:0030509 | Not Cancer Driver | No | 55 | 0.1095617529880478 | 64 | 4 | 0.0079681274900398 | 4 |
| BMPR2-202 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0030509 | Compendium | Yes | 100 | 0.0963391136801541 | 601 | 49 | 0.0472061657032755 | 17 |
| CHRD-201 | CHRD | Q9H2X0 | Chordin | chr3 | GO:0030509 | Not Cancer Driver | No | 119 | 0.1246073298429319 | 309 | 42 | 0.043979057591623 | 0 |
| CHRDL1-203 | CHRDL1 | Q9BU40 | Chordin-like protein 1 | chrX | GO:0030509 | Not Cancer Driver | No | 72 | 0.1578947368421052 | 68 | 8 | 0.0175438596491228 | 1 |
| COMP-201 | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0030509 | Not Cancer Driver | No | 75 | 0.0990752972258916 | 307 | 39 | 0.0515191545574636 | 51 |
| DDX5-201 | DDX5 | P17844 | Probable ATP-dependent RNA helicase DDX5 | chr17 | GO:0030509 | Census | Yes | 61 | 0.0993485342019544 | 225 | 18 | 0.0293159609120521 | 0 |
| DLX3-201 | DLX3 | O60479 | Homeobox protein DLX-3 | chr17 | GO:0030509 | Not Cancer Driver | No | 33 | 0.1149825783972125 | 204 | 22 | 0.0766550522648083 | 0 |
| DLX5-203 | DLX5 | P56178 | Homeobox protein DLX-5 | chr7 | GO:0030509 | Not Cancer Driver | No | 64 | 0.2214532871972318 | 223 | 54 | 0.1868512110726643 | 1 |
| DSG4-201 | DSG4 | Q86SJ6 | Desmoglein-4 | chr18 | GO:0030509 | Not Cancer Driver | No | 204 | 0.1961538461538461 | 187 | 35 | 0.0336538461538461 | 0 |
| EGR1-201 | EGR1 | P18146 | Early growth response protein 1 | chr5 | GO:0030509 | Not Cancer Driver | No | 63 | 0.1160220994475138 | 503 | 57 | 0.1049723756906077 | 0 |
| ENG-202 | ENG | P17813 | Endoglin | chr9 | GO:0030509 | Not Cancer Driver | No | 47 | 0.0714285714285714 | 114 | 11 | 0.0167173252279635 | 29 |
| ETV2-203 | ETV2 | O00321 | ETS translocation variant 2 | chr19 | GO:0030509 | Not Cancer Driver | No | 21 | 0.0614035087719298 | 228 | 14 | 0.0409356725146198 | 0 |
| EXT1-201 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0030509 | Census | Yes | 75 | 0.1005361930294906 | 60 | 7 | 0.0093833780160857 | 8 |
| FAM83G-201 | FAM83G | A6ND36 | Protein FAM83G | chr17 | GO:0030509 | Not Cancer Driver | No | 92 | 0.1117861482381531 | 532 | 57 | 0.0692588092345079 | 0 |
| FKBP8-206 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | GO:0030509 | Not Cancer Driver | No | 50 | 0.1213592233009708 | 161 | 19 | 0.0461165048543689 | 0 |
| FST-201 | FST | P19883 | Follistatin | chr5 | GO:0030509 | Not Cancer Driver | No | 33 | 0.0959302325581395 | 20 | 3 | 0.0087209302325581 | 0 |
| GDF2-201 | GDF2 | Q9UK05 | Growth/differentiation factor 2 | chr10 | GO:0030509 | Not Cancer Driver | No | 106 | 0.247086247086247 | 130 | 40 | 0.0932400932400932 | 3 |
| GDF5-201 | GDF5 | P43026 | Growth/differentiation factor 5 | chr20 | GO:0030509 | Not Cancer Driver | No | 89 | 0.1776447105788423 | 257 | 48 | 0.0958083832335329 | 23 |
| GDF6-201 | GDF6 | Q6KF10 | Growth/differentiation factor 6 | chr8 | GO:0030509 | Not Cancer Driver | No | 73 | 0.1604395604395604 | 225 | 38 | 0.0835164835164835 | 14 |
| GDF7-201 | GDF7 | Q7Z4P5 | Growth/differentiation factor 7 | chr2 | GO:0030509 | Not Cancer Driver | No | 26 | 0.0577777777777777 | 215 | 8 | 0.0177777777777777 | 0 |
| HES1-201 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0030509 | Not Cancer Driver | No | 35 | 0.125 | 227 | 30 | 0.1071428571428571 | 0 |
| HES5-201 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0030509 | Not Cancer Driver | No | 1 | 0.0060240963855421 | 73 | 0 | 0.0 | 0 |
| HFE-207 | HFE | Q30201 | Hereditary hemochromatosis protein | chr6 | GO:0030509 | Not Cancer Driver | No | 35 | 0.1005747126436781 | 27 | 2 | 0.0057471264367816 | 11 |
| HIVEP1-201 | HIVEP1 | P15822 | Zinc finger protein 40 | chr6 | GO:0030509 | Not Cancer Driver | No | 250 | 0.0919793966151582 | 2250 | 217 | 0.0798381162619573 | 0 |
| HJV-201 | HJV | Q6ZVN8 | Hemojuvelin | chr1 | GO:0030509 | Not Cancer Driver | No | 47 | 0.1103286384976525 | 117 | 16 | 0.0375586854460093 | 14 |
| LEF1-201 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0030509 | Census | Yes | 51 | 0.1278195488721804 | 372 | 47 | 0.1177944862155388 | 0 |
| MAPK3-201 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0030509 | Not Cancer Driver | No | 32 | 0.0844327176781002 | 49 | 3 | 0.0079155672823219 | 0 |
| MEGF8-201 | MEGF8 | Q7Z7M0 | Multiple epidermal growth factor-like domains protein 8 | chr19 | GO:0030509 | Not Cancer Driver | No | 246 | 0.0864674868189806 | 476 | 40 | 0.0140597539543057 | 3 |
| MSX1-201 | MSX1 | P28360 | Homeobox protein MSX-1 | chr4 | GO:0030509 | Not Cancer Driver | No | 32 | 0.1056105610561056 | 199 | 12 | 0.0396039603960396 | 7 |
| MSX2-201 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0030509 | Not Cancer Driver | No | 21 | 0.0786516853932584 | 170 | 10 | 0.0374531835205992 | 3 |
| NFIA-207 | NFIA | Q12857 | Nuclear factor 1 A-type | chr1 | GO:0030509 | Not Cancer Driver | No | 54 | 0.106090373280943 | 347 | 43 | 0.0844793713163064 | 0 |
| NOG-201 | NOG | Q13253 | Noggin | chr17 | GO:0030509 | Not Cancer Driver | No | 15 | 0.0646551724137931 | 87 | 5 | 0.021551724137931 | 17 |
| NOTCH2-201 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0030509 | Census, Compendium | Yes | 191 | 0.0772966410360178 | 631 | 61 | 0.0246863617968433 | 1 |
| PDCD4-201 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0030509 | Not Cancer Driver | No | 49 | 0.1044776119402985 | 188 | 25 | 0.0533049040511727 | 0 |
| PPARG-201 | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0030509 | Census | Yes | 60 | 0.1188118811881188 | 44 | 3 | 0.0059405940594059 | 3 |
| RGMA-201 | RGMA | Q96B86 | Repulsive guidance molecule A | chr15 | GO:0030509 | Not Cancer Driver | No | 40 | 0.0888888888888888 | 105 | 12 | 0.0266666666666666 | 0 |
| RGMB-207 | RGMB | Q6NW40 | Repulsive guidance molecule B | chr5 | GO:0030509 | Not Cancer Driver | No | 26 | 0.0594965675057208 | 85 | 10 | 0.022883295194508 | 0 |
| RUNX2-212 | RUNX2 | Q13950 | Runt-related transcription factor 2 | chr6 | GO:0030509 | Not Cancer Driver | No | 50 | 0.0959692898272552 | 447 | 44 | 0.0844529750479846 | 30 |
| SCX-201 | SCX | Q7RTU7 | Basic helix-loop-helix transcription factor scleraxis | chr8 | GO:0030509 | Not Cancer Driver | No | 0 | 0.0 | 191 | 0 | 0.0 | 0 |
| SFRP1-201 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0030509 | Not Cancer Driver | No | 31 | 0.0987261146496815 | 39 | 4 | 0.0127388535031847 | 0 |
| SFRP2-201 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0030509 | Not Cancer Driver | No | 37 | 0.1254237288135593 | 1 | 0 | 0.0 | 0 |
| SLC39A5-209 | SLC39A5 | Q6ZMH5 | Zinc transporter ZIP5 | chr12 | GO:0030509 | Not Cancer Driver | No | 48 | 0.0888888888888888 | 140 | 15 | 0.0277777777777777 | 1 |
| SMAD1-201 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0030509 | Not Cancer Driver | No | 39 | 0.0838709677419354 | 162 | 19 | 0.0408602150537634 | 0 |
| SMAD4-201 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0030509 | Census, Compendium | Yes | 172 | 0.3115942028985507 | 195 | 16 | 0.0289855072463768 | 6 |
| SMAD5-211 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0030509 | Not Cancer Driver | No | 25 | 0.053763440860215 | 172 | 6 | 0.0129032258064516 | 0 |
| SMAD6-201 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0030509 | Not Cancer Driver | No | 29 | 0.0584677419354838 | 249 | 4 | 0.0080645161290322 | 7 |
| SMAD9-202 | SMAD9 | O15198 | Mothers against decapentaplegic homolog 9 | chr13 | GO:0030509 | Not Cancer Driver | No | 64 | 0.1370449678800856 | 132 | 14 | 0.0299785867237687 | 1 |
| SMPD3-201 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0030509 | Not Cancer Driver | No | 73 | 0.1114503816793893 | 224 | 26 | 0.0396946564885496 | 0 |
| SMURF1-201 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:0030509 | Not Cancer Driver | No | 60 | 0.0792602377807133 | 257 | 19 | 0.0250990752972258 | 0 |
| SOST-201 | SOST | Q9BQB4 | Sclerostin | chr17 | GO:0030509 | Not Cancer Driver | No | 24 | 0.1126760563380281 | 90 | 10 | 0.0469483568075117 | 2 |
| SOSTDC1-201 | SOSTDC1 | Q6X4U4 | Sclerostin domain-containing protein 1 | chr7 | GO:0030509 | Not Cancer Driver | No | 14 | 0.0679611650485436 | 72 | 1 | 0.0048543689320388 | 0 |
| SPART-202 | SPART | Q8N0X7 | Spartin | chr13 | GO:0030509 | Not Cancer Driver | No | 77 | 0.1156156156156156 | 397 | 49 | 0.0735735735735735 | 1 |
| TGFBR3-201 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0030509 | Not Cancer Driver | No | 104 | 0.1222091656874265 | 268 | 36 | 0.0423031727379553 | 0 |
| TMEM100-201 | TMEM100 | Q9NV29 | Transmembrane protein 100 | chr17 | GO:0030509 | Not Cancer Driver | No | 22 | 0.1641791044776119 | 0 | 0 | 0.0 | 0 |
| TMPRSS6-208 | TMPRSS6 | Q8IU80 | Transmembrane protease serine 6 | chr22 | GO:0030509 | Not Cancer Driver | No | 100 | 0.1246882793017456 | 40 | 5 | 0.0062344139650872 | 23 |
| TWSG1-201 | TWSG1 | Q9GZX9 | Twisted gastrulation protein homolog 1 | chr18 | GO:0030509 | Not Cancer Driver | No | 20 | 0.0896860986547085 | 19 | 2 | 0.0089686098654708 | 0 |
| USP15-201 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | GO:0030509 | Not Cancer Driver | No | 103 | 0.1049949031600407 | 260 | 31 | 0.0316004077471967 | 0 |
| USP9X-202 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0030509 | Census, Compendium | Yes | 243 | 0.0951448707909162 | 405 | 33 | 0.0129209083790133 | 1 |
| USP9Y-201 | USP9Y | O00507 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y | chrY | GO:0030509 | Not Cancer Driver | No | 60 | 0.0234833659491193 | 349 | 6 | 0.0023483365949119 | 0 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0030509 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |
| ZNF8-201 | ZNF8 | P17098 | Zinc finger protein 8 | chr19 | GO:0030509 | Not Cancer Driver | No | 70 | 0.1217391304347826 | 410 | 46 | 0.08 | 0 |