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Total number of protein in "GO:0030659" GO term:  119

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA3-201 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0030659 Not Cancer Driver No 168 0.0985915492957746 77 4 0.0023474178403755 13
ABCC11-202 ABCC11 Q96J66 ATP-binding cassette sub-family C member 11 chr16 GO:0030659 Not Cancer Driver No 197 0.142547033285094 91 11 0.0079594790159189 0
AGTRAP-201 AGTRAP Q6RW13 Type-1 angiotensin II receptor-associated protein chr1 GO:0030659 Not Cancer Driver No 15 0.0943396226415094 11 0 0.0 0
ANKRD27-201 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0030659 Not Cancer Driver No 102 0.0971428571428571 239 27 0.0257142857142857 0
AP1B1-202 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 GO:0030659 Not Cancer Driver No 84 0.0885142255005268 119 7 0.0073761854583772 1
AP1G1-201 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0030659 Not Cancer Driver No 77 0.0936739659367396 144 20 0.024330900243309 5
AP1M1-201 AP1M1 Q9BXS5 AP-1 complex subunit mu-1 chr19 GO:0030659 Not Cancer Driver No 55 0.1300236406619385 38 11 0.0260047281323877 0
AP1M2-201 AP1M2 Q9Y6Q5 AP-1 complex subunit mu-2 chr19 GO:0030659 Not Cancer Driver No 43 0.1016548463356974 15 0 0.0 0
AP1S1-201 AP1S1 P61966 AP-1 complex subunit sigma-1A chr7 GO:0030659 Not Cancer Driver No 15 0.0949367088607595 0 0 0.0 0
AP1S2-201 AP1S2 P56377 AP-1 complex subunit sigma-2 chrX GO:0030659 Not Cancer Driver No 13 0.0828025477707006 0 0 0.0 0
AP1S3-208 AP1S3 Q96PC3 AP-1 complex subunit sigma-3 chr2 GO:0030659 Not Cancer Driver No 19 0.1233766233766233 0 0 0.0 2
AP3M1-201 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 GO:0030659 Not Cancer Driver No 33 0.0789473684210526 19 1 0.0023923444976076 0
AP3M2-201 AP3M2 P53677 AP-3 complex subunit mu-2 chr8 GO:0030659 Not Cancer Driver No 39 0.0933014354066985 55 3 0.0071770334928229 0
AP3S1-201 AP3S1 Q92572 AP-3 complex subunit sigma-1 chr5 GO:0030659 Not Cancer Driver No 20 0.1036269430051813 0 0 0.0 0
AP3S2-201 AP3S2 P59780 AP-3 complex subunit sigma-2 chr15 GO:0030659 Not Cancer Driver No 19 0.0984455958549222 0 0 0.0 0
APPBP2-201 APPBP2 Q92624 Amyloid protein-binding protein 2 chr17 GO:0030659 Not Cancer Driver No 46 0.0786324786324786 10 0 0.0 0
AQP11-201 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0030659 Not Cancer Driver No 15 0.055350553505535 0 0 0.0 0
AQP5-201 AQP5 P55064 Aquaporin-5 chr12 GO:0030659 Not Cancer Driver No 25 0.0943396226415094 21 1 0.0037735849056603 5
AQP6-201 AQP6 Q13520 Aquaporin-6 chr12 GO:0030659 Not Cancer Driver No 38 0.1347517730496454 22 4 0.0141843971631205 0
AQP7-201 AQP7 O14520 Aquaporin-7 chr9 GO:0030659 Not Cancer Driver No 39 0.1140350877192982 29 1 0.0029239766081871 0
ARHGAP21-202 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 GO:0030659 Not Cancer Driver No 168 0.0858018386108273 1613 140 0.0715015321756894 0
ARRB1-202 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0030659 Not Cancer Driver No 37 0.0885167464114832 154 11 0.0263157894736842 0
BAIAP2L2-202 BAIAP2L2 Q6UXY1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 chr22 GO:0030659 Not Cancer Driver No 21 0.0396975425330812 342 11 0.0207939508506616 0
C2CD5-201 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 GO:0030659 Not Cancer Driver No 82 0.082 251 21 0.021 0
CADPS2-204 CADPS2 Q86UW7 Calcium-dependent secretion activator 2 chr7 GO:0030659 Not Cancer Driver No 144 0.1111111111111111 202 18 0.0138888888888888 0
CALY-201 CALY Q9NYX4 Neuron-specific vesicular protein calcyon chr10 GO:0030659 Not Cancer Driver No 7 0.032258064516129 133 5 0.0230414746543778 0
CAMKV-209 CAMKV Q8NCB2 CaM kinase-like vesicle-associated protein chr3 GO:0030659 Not Cancer Driver No 67 0.1337325349301397 226 22 0.0439121756487025 0
CLIC4-201 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0030659 Not Cancer Driver No 23 0.0909090909090909 49 4 0.0158102766798418 0
CLIP1-219 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0030659 Census, Compendium Yes 98 0.0681502086230876 1200 72 0.0500695410292072 0
CYB561D2-205 CYB561D2 O14569 Transmembrane reductase CYB561D2 chr3 GO:0030659 Not Cancer Driver No 6 0.027027027027027 0 0 0.0 0
DENND4C-209 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 GO:0030659 Not Cancer Driver No 121 0.0633839706652697 709 40 0.0209533787323205 0
DISP3-201 DISP3 Q9P2K9 Protein dispatched homolog 3 chr1 GO:0030659 Not Cancer Driver No 268 0.1925287356321839 174 34 0.0244252873563218 0
DSE-213 DSE Q9UL01 Dermatan-sulfate epimerase chr6 GO:0030659 Not Cancer Driver No 108 0.1127348643006263 38 2 0.0020876826722338 1
DYSF-201 DYSF O75923 Dysferlin chr2 GO:0030659 Not Cancer Driver No 364 0.175 329 49 0.0235576923076923 52
ECE2-201 ECE2 P0DPD6 Endothelin-converting enzyme 2 chr3 GO:0030659 Not Cancer Driver No 120 0.1479654747225647 150 22 0.0271270036991368 0
ENTPD7-201 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0030659 Not Cancer Driver No 64 0.1059602649006622 26 3 0.0049668874172185 0
FLRT1-202 FLRT1 Q9NZU1 Leucine-rich repeat transmembrane protein FLRT1 chr11 GO:0030659 Not Cancer Driver No 58 0.086053412462908 95 5 0.0074183976261127 0
FMN2-201 FMN2 Q9NZ56 Formin-2 chr1 GO:0030659 Not Cancer Driver No 222 0.1289198606271777 1327 218 0.1265969802555168 0
FZD6-201 FZD6 O60353 Frizzled-6 chr8 GO:0030659 Not Cancer Driver No 60 0.0849858356940509 173 14 0.0198300283286118 1
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 GO:0030659 Not Cancer Driver No 10 0.0854700854700854 10 1 0.0085470085470085 0
GABRA1-202 GABRA1 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 chr5 GO:0030659 Not Cancer Driver No 131 0.2872807017543859 58 25 0.0548245614035087 6
GABRB2-203 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0030659 Not Cancer Driver No 125 0.244140625 27 9 0.017578125 1
GABRB3-202 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0030659 Not Cancer Driver No 147 0.3107822410147992 56 16 0.0338266384778012 9
GABRG2-215 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0030659 Not Cancer Driver No 155 0.3263157894736842 2 0 0.0 11
GBP1-201 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0030659 Not Cancer Driver No 60 0.1013513513513513 166 19 0.0320945945945945 0
GBP2-201 GBP2 P32456 Guanylate-binding protein 2 chr1 GO:0030659 Not Cancer Driver No 55 0.093062605752961 135 12 0.0203045685279187 0
GBP5-201 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 GO:0030659 Not Cancer Driver No 80 0.136518771331058 170 18 0.030716723549488 0
GBP7-201 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0030659 Not Cancer Driver No 61 0.0956112852664576 93 8 0.012539184952978 0
GDE1-201 GDE1 Q9NZC3 Glycerophosphodiester phosphodiesterase 1 chr16 GO:0030659 Not Cancer Driver No 27 0.0815709969788519 37 1 0.0030211480362537 0
GPER1-202 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0030659 Not Cancer Driver No 47 0.1253333333333333 13 4 0.0106666666666666 0
GPR18-202 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0030659 Not Cancer Driver No 27 0.0815709969788519 0 0 0.0 0
GPRC5A-201 GPRC5A Q8NFJ5 Retinoic acid-induced protein 3 chr12 GO:0030659 Not Cancer Driver No 29 0.0812324929971988 19 2 0.0056022408963585 0
GPRC5B-201 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0030659 Not Cancer Driver No 72 0.1786600496277915 76 19 0.0471464019851116 0
GPRC5C-202 GPRC5C Q9NQ84 G-protein coupled receptor family C group 5 member C chr17 GO:0030659 Not Cancer Driver No 61 0.1383219954648526 58 13 0.0294784580498866 0
GRIN2A-201 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0030659 Census, Compendium Yes 439 0.2998633879781421 507 172 0.1174863387978142 32
HTT-201 HTT P42858 Huntingtin chr4 GO:0030659 Not Cancer Driver No 261 0.0830681094844048 668 51 0.0162316995544239 2
IFNGR2-201 IFNGR2 P38484 Interferon gamma receptor 2 chr21 GO:0030659 Not Cancer Driver No 22 0.0652818991097922 18 1 0.0029673590504451 5
IL15RA-204 IL15RA Q13261 Interleukin-15 receptor subunit alpha chr10 GO:0030659 Not Cancer Driver No 26 0.097378277153558 171 20 0.0749063670411985 0
IYD-202 IYD Q6PHW0 Iodotyrosine deiodinase 1 chr6 GO:0030659 Not Cancer Driver No 27 0.0934256055363321 75 10 0.0346020761245674 2
KCNJ4-201 KCNJ4 P48050 Inward rectifier potassium channel 4 chr22 GO:0030659 Not Cancer Driver No 81 0.1820224719101123 63 12 0.0269662921348314 0
KCNQ1-201 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0030659 Not Cancer Driver No 55 0.0813609467455621 219 14 0.0207100591715976 109
KIF1B-214 KIF1B O60333 Kinesin-like protein KIF1B chr1 GO:0030659 Not Cancer Driver No 187 0.1029735682819383 634 82 0.0451541850220264 1
KIFC3-201 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 GO:0030659 Not Cancer Driver No 60 0.0720288115246098 488 34 0.0408163265306122 0
LAMP5-201 LAMP5 Q9UJQ1 Lysosome-associated membrane glycoprotein 5 chr20 GO:0030659 Not Cancer Driver No 73 0.2607142857142857 40 16 0.0571428571428571 0
LNPEP-201 LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 GO:0030659 Not Cancer Driver No 80 0.0780487804878048 103 5 0.0048780487804878 0
LRIG3-201 LRIG3 Q6UXM1 Leucine-rich repeats and immunoglobulin-like domains protein 3 chr12 GO:0030659 Census, Compendium Yes 104 0.0929401251117068 231 25 0.0223413762287756 0
MALRD1-204 MALRD1 Q5VYJ5 MAM and LDL-receptor class A domain-containing protein 1 chr10 GO:0030659 Not Cancer Driver No 21 0.0097402597402597 130 1 0.0004638218923933 0
MARCHF11-201 MARCHF11 A6NNE9 E3 ubiquitin-protein ligase MARCHF11 chr5 GO:0030659 Not Cancer Driver No 73 0.181592039800995 177 5 0.0124378109452736 0
MFSD10-202 MFSD10 Q14728 Major facilitator superfamily domain-containing protein 10 chr4 GO:0030659 Not Cancer Driver No 40 0.0879120879120879 18 1 0.0021978021978021 0
MREG-201 MREG Q8N565 Melanoregulin chr2 GO:0030659 Not Cancer Driver No 18 0.0841121495327102 24 3 0.014018691588785 0
MYO1C-220 MYO1C O00159 Unconventional myosin-Ic chr17 GO:0030659 Not Cancer Driver No 86 0.0809031044214487 66 9 0.0084666039510818 0
MYO5B-201 MYO5B Q9ULV0 Unconventional myosin-Vb chr18 GO:0030659 Not Cancer Driver No 205 0.1109307359307359 507 53 0.0286796536796536 23
NMNAT2-201 NMNAT2 Q9BZQ4 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 chr1 GO:0030659 Not Cancer Driver No 41 0.1335504885993485 22 1 0.003257328990228 0
NPC1L1-201 NPC1L1 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 chr7 GO:0030659 Not Cancer Driver No 172 0.1265636497424576 8 1 0.0007358351729212 0
NSG2-201 NSG2 Q9Y328 Neuronal vesicle trafficking-associated protein 2 chr5 GO:0030659 Not Cancer Driver No 26 0.1520467836257309 43 6 0.0350877192982456 0
PACSIN1-201 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 GO:0030659 Not Cancer Driver No 41 0.0923423423423423 319 37 0.0833333333333333 0
PDE6D-201 PDE6D O43924 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta chr2 GO:0030659 Not Cancer Driver No 15 0.1 1 0 0.0 0
PKD2-201 PKD2 Q13563 Polycystin-2 chr4 GO:0030659 Not Cancer Driver No 88 0.0909090909090909 376 30 0.03099173553719 9
RAB10-201 RAB10 P61026 Ras-related protein Rab-10 chr2 GO:0030659 Not Cancer Driver No 12 0.06 28 1 0.005 0
RAB11A-201 RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0030659 Not Cancer Driver No 12 0.0555555555555555 43 2 0.0092592592592592 0
RAB11FIP2-201 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 GO:0030659 Not Cancer Driver No 41 0.080078125 356 24 0.046875 0
RAB39B-201 RAB39B Q96DA2 Ras-related protein Rab-39B chrX GO:0030659 Not Cancer Driver No 32 0.1502347417840375 0 0 0.0 2
RAB4A-201 RAB4A P20338 Ras-related protein Rab-4A chr1 GO:0030659 Not Cancer Driver No 15 0.0688073394495412 32 8 0.036697247706422 0
RALA-201 RALA P11233 Ras-related protein Ral-A chr7 GO:0030659 Not Cancer Driver No 29 0.1407766990291262 34 3 0.0145631067961165 4
SAYSD1-201 SAYSD1 Q9NPB0 SAYSvFN domain-containing protein 1 chr6 GO:0030659 Not Cancer Driver No 13 0.0710382513661202 68 3 0.0163934426229508 0
SCNN1B-202 SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0030659 Not Cancer Driver No 64 0.1 62 4 0.00625 12
SGSM1-202 SGSM1 Q2NKQ1 Small G protein signaling modulator 1 chr22 GO:0030659 Not Cancer Driver No 151 0.1315331010452961 421 50 0.0435540069686411 0
SH3BP5-202 SH3BP5 O60239 SH3 domain-binding protein 5 chr3 GO:0030659 Not Cancer Driver No 33 0.0725274725274725 380 23 0.0505494505494505 0
SH3KBP1-205 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX GO:0030659 Not Cancer Driver No 65 0.0977443609022556 532 49 0.0736842105263157 0
SLC12A2-201 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0030659 Not Cancer Driver No 97 0.08003300330033 297 13 0.0107260726072607 8
SLC26A6-205 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0030659 Not Cancer Driver No 54 0.0711462450592885 88 13 0.0171277997364953 0
SLC2A4-201 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0030659 Not Cancer Driver No 47 0.0923379174852652 44 6 0.0117878192534381 1
SLC30A1-201 SLC30A1 Q9Y6M5 Proton-coupled zinc antiporter SLC30A1 chr1 GO:0030659 Not Cancer Driver No 44 0.0867850098619329 144 9 0.0177514792899408 0
SLC39A13-202 SLC39A13 Q96H72 Zinc transporter ZIP13 chr11 GO:0030659 Not Cancer Driver No 35 0.0943396226415094 18 1 0.0026954177897574 0
SMAGP-203 SMAGP Q0VAQ4 Small cell adhesion glycoprotein chr12 GO:0030659 Not Cancer Driver No 9 0.0927835051546391 38 5 0.0515463917525773 0
SNX15-202 SNX15 Q9NRS6 Sorting nexin-15 chr11 GO:0030659 Not Cancer Driver No 40 0.1169590643274853 221 20 0.0584795321637426 0
SNX22-201 SNX22 Q96L94 Sorting nexin-22 chr15 GO:0030659 Not Cancer Driver No 10 0.0518134715025906 70 4 0.0207253886010362 0
SNX24-201 SNX24 Q9Y343 Sorting nexin-24 chr5 GO:0030659 Not Cancer Driver No 19 0.1124260355029585 14 3 0.0177514792899408 0
SNX33-201 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0030659 Not Cancer Driver No 48 0.0836236933797909 205 15 0.0261324041811846 0
SNX9-201 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0030659 Not Cancer Driver No 50 0.0840336134453781 233 19 0.0319327731092436 0
SPIRE1-202 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0030659 Not Cancer Driver No 46 0.0608465608465608 415 29 0.0383597883597883 0
SPIRE2-201 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:0030659 Not Cancer Driver No 68 0.0952380952380952 344 38 0.0532212885154061 0
STING1-201 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0030659 Not Cancer Driver No 39 0.1029023746701846 66 12 0.0316622691292876 4
TAOK2-202 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0030659 Not Cancer Driver No 129 0.1044534412955465 668 68 0.0550607287449392 0
TBC1D24-210 TBC1D24 Q9ULP9 TBC1 domain family member 24 chr16 GO:0030659 Not Cancer Driver No 50 0.0894454382826475 33 1 0.0017889087656529 16
TMEM184A-201 TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 GO:0030659 Not Cancer Driver No 45 0.1089588377723971 76 12 0.0290556900726392 0
TMEM67-205 TMEM67 Q5HYA8 Meckelin chr8 GO:0030659 Not Cancer Driver No 85 0.0854271356783919 11 0 0.0 45
TNK2-201 TNK2 Q07912 Activated CDC42 kinase 1 chr3 GO:0030659 Not Cancer Driver No 103 0.0992292870905587 598 66 0.0635838150289017 0
TOR1A-201 TOR1A O14656 Torsin-1A chr9 GO:0030659 Not Cancer Driver No 26 0.0783132530120482 0 0 0.0 3
TRARG1-201 TRARG1 Q8IXB3 Trafficking regulator of GLUT4 1 chr17 GO:0030659 Not Cancer Driver No 26 0.1468926553672316 85 10 0.0564971751412429 0
TRIM72-201 TRIM72 Q6ZMU5 Tripartite motif-containing protein 72 chr16 GO:0030659 Not Cancer Driver No 43 0.090146750524109 69 11 0.0230607966457023 0
TRPM2-203 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0030659 Not Cancer Driver No 224 0.1490352628077179 267 37 0.0246174318030605 0
ULK2-202 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 GO:0030659 Not Cancer Driver No 99 0.0955598455598455 520 70 0.0675675675675675 0
VAMP5-201 VAMP5 O95183 Vesicle-associated membrane protein 5 chr2 GO:0030659 Not Cancer Driver No 13 0.1120689655172413 19 1 0.0086206896551724 0
VOPP1-201 VOPP1 Q96AW1 Vesicular, overexpressed in cancer, prosurvival protein 1 chr7 GO:0030659 Not Cancer Driver No 19 0.1104651162790697 52 4 0.0232558139534883 0
WHAMM-201 WHAMM Q8TF30 WASP homolog-associated protein with actin, membranes and microtubules chr15 GO:0030659 Not Cancer Driver No 42 0.0519159456118665 401 30 0.0370828182941903 0
YKT6-201 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 GO:0030659 Not Cancer Driver No 11 0.0555555555555555 21 1 0.005050505050505 0
ZNRF2-201 ZNRF2 Q8NHG8 E3 ubiquitin-protein ligase ZNRF2 chr7 GO:0030659 Not Cancer Driver No 10 0.0413223140495867 148 0 0.0 0
ZPLD1-202 ZPLD1 Q8TCW7 Zona pellucida-like domain-containing protein 1 chr3 GO:0030659 Not Cancer Driver No 96 0.2313253012048192 49 16 0.0385542168674698 0