Total number of protein in "GO:0031295" GO term: 42
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0031295 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| CARD11-203 | CARD11 | Q9BXL7 | Caspase recruitment domain-containing protein 11 | chr7 | GO:0031295 | Census, Compendium | Yes | 251 | 0.2175043327556325 | 534 | 116 | 0.1005199306759098 | 5 |
| CAV1-201 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0031295 | Not Cancer Driver | No | 23 | 0.1292134831460674 | 2 | 0 | 0.0 | 0 |
| CCL19-201 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0031295 | Not Cancer Driver | No | 5 | 0.0510204081632653 | 7 | 0 | 0.0 | 0 |
| CCL21-201 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0031295 | Not Cancer Driver | No | 12 | 0.0895522388059701 | 59 | 5 | 0.0373134328358208 | 0 |
| CD160-202 | CD160 | O95971 | CD160 antigen | chr1 | GO:0031295 | Not Cancer Driver | No | 16 | 0.0883977900552486 | 2 | 0 | 0.0 | 0 |
| CD24-201 | CD24 | P25063 | Signal transducer CD24 | chr6 | GO:0031295 | Not Cancer Driver | No | 0 | 0.0 | 32 | 0 | 0.0 | 0 |
| CD274-202 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | GO:0031295 | Census | Yes | 26 | 0.0896551724137931 | 54 | 9 | 0.0310344827586206 | 0 |
| CD28-201 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0031295 | Census | Yes | 26 | 0.1181818181818181 | 18 | 6 | 0.0272727272727272 | 0 |
| CD3E-201 | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | GO:0031295 | Not Cancer Driver | No | 16 | 0.0772946859903381 | 72 | 6 | 0.0289855072463768 | 0 |
| CD40LG-202 | CD40LG | P29965 | CD40 ligand | chrX | GO:0031295 | Not Cancer Driver | No | 34 | 0.1302681992337164 | 24 | 4 | 0.0153256704980842 | 27 |
| CD5-201 | CD5 | P06127 | T-cell surface glycoprotein CD5 | chr11 | GO:0031295 | Not Cancer Driver | No | 44 | 0.0888888888888888 | 148 | 11 | 0.0222222222222222 | 0 |
| CD80-201 | CD80 | P33681 | T-lymphocyte activation antigen CD80 | chr3 | GO:0031295 | Not Cancer Driver | No | 33 | 0.1145833333333333 | 27 | 1 | 0.0034722222222222 | 0 |
| CD86-202 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:0031295 | Not Cancer Driver | No | 64 | 0.1945288753799392 | 56 | 10 | 0.0303951367781155 | 0 |
| CSK-201 | CSK | P41240 | Tyrosine-protein kinase CSK | chr15 | GO:0031295 | Not Cancer Driver | No | 37 | 0.0822222222222222 | 18 | 1 | 0.0022222222222222 | 0 |
| DPP4-201 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | GO:0031295 | Not Cancer Driver | No | 108 | 0.1409921671018277 | 8 | 0 | 0.0 | 0 |
| EFNB1-201 | EFNB1 | P98172 | Ephrin-B1 | chrX | GO:0031295 | Not Cancer Driver | No | 35 | 0.1011560693641618 | 126 | 10 | 0.0289017341040462 | 14 |
| EFNB2-202 | EFNB2 | P52799 | Ephrin-B2 | chr13 | GO:0031295 | Not Cancer Driver | No | 37 | 0.1111111111111111 | 99 | 11 | 0.033033033033033 | 0 |
| EFNB3-201 | EFNB3 | Q15768 | Ephrin-B3 | chr17 | GO:0031295 | Not Cancer Driver | No | 37 | 0.1088235294117647 | 183 | 18 | 0.0529411764705882 | 0 |
| FYN-202 | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0031295 | Not Cancer Driver | No | 64 | 0.1191806331471136 | 71 | 11 | 0.0204841713221601 | 0 |
| HHLA2-206 | HHLA2 | Q9UM44 | HERV-H LTR-associating protein 2 | chr3 | GO:0031295 | Not Cancer Driver | No | 65 | 0.1570048309178744 | 58 | 9 | 0.0217391304347826 | 0 |
| ICOS-201 | ICOS | Q9Y6W8 | Inducible T-cell costimulator | chr2 | GO:0031295 | Not Cancer Driver | No | 30 | 0.1507537688442211 | 0 | 0 | 0.0 | 0 |
| KLRK1-201 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0031295 | Not Cancer Driver | No | 35 | 0.162037037037037 | 0 | 0 | 0.0 | 0 |
| LCK-202 | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0031295 | Census | Yes | 76 | 0.1493123772102161 | 95 | 12 | 0.0235756385068762 | 1 |
| LGALS1-201 | LGALS1 | P09382 | Galectin-1 | chr22 | GO:0031295 | Not Cancer Driver | No | 15 | 0.1111111111111111 | 0 | 0 | 0.0 | 0 |
| LYN-202 | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0031295 | Census | Yes | 78 | 0.15234375 | 85 | 10 | 0.01953125 | 0 |
| MAP3K8-201 | MAP3K8 | P41279 | Mitogen-activated protein kinase kinase kinase 8 | chr10 | GO:0031295 | Not Cancer Driver | No | 45 | 0.0963597430406852 | 109 | 6 | 0.012847965738758 | 0 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0031295 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
| PDCD1LG2-201 | PDCD1LG2 | Q9BQ51 | Programmed cell death 1 ligand 2 | chr9 | GO:0031295 | Census, Compendium | Yes | 26 | 0.0952380952380952 | 42 | 8 | 0.0293040293040293 | 0 |
| PDPK1-202 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0031295 | Not Cancer Driver | No | 23 | 0.0413669064748201 | 121 | 9 | 0.0161870503597122 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0031295 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PTPN11-201 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0031295 | Census, Compendium | Yes | 92 | 0.1551433389544688 | 260 | 27 | 0.0455311973018549 | 44 |
| PTPN6-201 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:0031295 | Census, Compendium | Yes | 52 | 0.0873949579831932 | 194 | 20 | 0.0336134453781512 | 0 |
| SPN-206 | SPN | P16150 | Leukosialin | chr16 | GO:0031295 | Not Cancer Driver | No | 37 | 0.0925 | 359 | 29 | 0.0725 | 0 |
| SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0031295 | Census | Yes | 40 | 0.0746268656716417 | 130 | 10 | 0.0186567164179104 | 1 |
| TMIGD2-201 | TMIGD2 | Q96BF3 | Transmembrane and immunoglobulin domain-containing protein 2 | chr19 | GO:0031295 | Not Cancer Driver | No | 35 | 0.1241134751773049 | 122 | 21 | 0.0744680851063829 | 0 |
| TNFRSF13C-201 | TNFRSF13C | Q96RJ3 | Tumor necrosis factor receptor superfamily member 13C | chr22 | GO:0031295 | Not Cancer Driver | No | 15 | 0.0815217391304347 | 128 | 13 | 0.0706521739130434 | 0 |
| TNFRSF14-201 | TNFRSF14 | Q92956 | Tumor necrosis factor receptor superfamily member 14 | chr1 | GO:0031295 | Census, Compendium | Yes | 26 | 0.0918727915194346 | 54 | 4 | 0.0141342756183745 | 0 |
| TNFSF13B-201 | TNFSF13B | Q9Y275 | Tumor necrosis factor ligand superfamily member 13B | chr13 | GO:0031295 | Not Cancer Driver | No | 30 | 0.1052631578947368 | 91 | 13 | 0.0456140350877193 | 0 |
| TNFSF14-203 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0031295 | Not Cancer Driver | No | 44 | 0.1833333333333333 | 19 | 2 | 0.0083333333333333 | 0 |
| VAV1-210 | VAV1 | P15498 | Proto-oncogene vav | chr19 | GO:0031295 | Census, Compendium | Yes | 128 | 0.1514792899408284 | 113 | 18 | 0.0213017751479289 | 0 |
| YES1-201 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0031295 | Not Cancer Driver | No | 48 | 0.0883977900552486 | 63 | 9 | 0.0165745856353591 | 0 |