Total number of protein in "GO:0031490" GO term: 82
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN4-201 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | GO:0031490 | Not Cancer Driver | No | 110 | 0.1207464324917673 | 244 | 36 | 0.0395170142700329 | 7 |
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0031490 | Not Cancer Driver | No | 23 | 0.0723270440251572 | 104 | 9 | 0.0283018867924528 | 0 |
| ATOH1-201 | ATOH1 | Q92858 | Transcription factor ATOH1 | chr4 | GO:0031490 | Not Cancer Driver | No | 54 | 0.1525423728813559 | 329 | 46 | 0.1299435028248587 | 0 |
| ATRX-201 | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0031490 | Census, Compendium | Yes | 306 | 0.1227929373996789 | 1673 | 173 | 0.069422150882825 | 29 |
| BAP1-202 | BAP1 | Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | chr3 | GO:0031490 | Census, Compendium | Yes | 116 | 0.1591220850480109 | 419 | 42 | 0.0576131687242798 | 4 |
| BCL6-202 | BCL6 | P41182 | B-cell lymphoma 6 protein | chr3 | GO:0031490 | Census, Compendium | Yes | 91 | 0.1288951841359773 | 328 | 45 | 0.0637393767705382 | 0 |
| CEBPA-201 | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0031490 | Census, Compendium | Yes | 10 | 0.0279329608938547 | 343 | 10 | 0.0279329608938547 | 1 |
| CEBPB-201 | CEBPB | P17676 | CCAAT/enhancer-binding protein beta | chr20 | GO:0031490 | Not Cancer Driver | No | 2 | 0.0057971014492753 | 276 | 0 | 0.0 | 0 |
| CLOCK-211 | CLOCK | O15516 | Circadian locomoter output cycles protein kaput | chr4 | GO:0031490 | Not Cancer Driver | No | 56 | 0.0661938534278959 | 459 | 25 | 0.0295508274231678 | 0 |
| CREBBP-201 | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0031490 | Census, Compendium | Yes | 217 | 0.0888615888615888 | 1801 | 91 | 0.0372645372645372 | 30 |
| DHX9-201 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | GO:0031490 | Compendium | Yes | 125 | 0.0984251968503937 | 332 | 30 | 0.0236220472440944 | 0 |
| EOMES-201 | EOMES | O95936 | Eomesodermin homolog | chr3 | GO:0031490 | Not Cancer Driver | No | 64 | 0.0932944606413994 | 435 | 41 | 0.0597667638483965 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0031490 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| EZH2-203 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0031490 | Census, Compendium | Yes | 74 | 0.099195710455764 | 284 | 32 | 0.0428954423592493 | 11 |
| FOXC2-201 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0031490 | Not Cancer Driver | No | 52 | 0.1037924151696606 | 370 | 31 | 0.06187624750499 | 1 |
| FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0031490 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
| FOXO3-202 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0031490 | Census, Compendium | Yes | 54 | 0.0802377414561664 | 597 | 50 | 0.0742942050520059 | 0 |
| GATA1-202 | GATA1 | P15976 | Erythroid transcription factor | chrX | GO:0031490 | Census, Compendium | Yes | 57 | 0.1380145278450363 | 242 | 34 | 0.0823244552058111 | 5 |
| GRHL1-201 | GRHL1 | Q9NZI5 | Grainyhead-like protein 1 homolog | chr2 | GO:0031490 | Not Cancer Driver | No | 72 | 0.116504854368932 | 261 | 29 | 0.046925566343042 | 0 |
| GRHL2-206 | GRHL2 | Q6ISB3 | Grainyhead-like protein 2 homolog | chr8 | GO:0031490 | Not Cancer Driver | No | 73 | 0.1168 | 260 | 33 | 0.0528 | 2 |
| GRHL3-202 | GRHL3 | Q8TE85 | Grainyhead-like protein 3 homolog | chr1 | GO:0031490 | Not Cancer Driver | No | 66 | 0.1054313099041533 | 294 | 36 | 0.0575079872204472 | 3 |
| H1-0-201 | H1-0 | P07305 | Histone H1.0 | chr22 | GO:0031490 | Not Cancer Driver | No | 6 | 0.0309278350515463 | 194 | 6 | 0.0309278350515463 | 0 |
| H1-1-201 | H1-1 | Q02539 | Histone H1.1 | chr6 | GO:0031490 | Not Cancer Driver | No | 13 | 0.0604651162790697 | 212 | 12 | 0.055813953488372 | 0 |
| H1-2-201 | H1-2 | P16403 | Histone H1.2 | chr6 | GO:0031490 | Not Cancer Driver | No | 28 | 0.1314553990610328 | 214 | 28 | 0.1314553990610328 | 0 |
| H1-3-201 | H1-3 | P16402 | Histone H1.3 | chr6 | GO:0031490 | Not Cancer Driver | No | 14 | 0.0633484162895927 | 216 | 12 | 0.0542986425339366 | 0 |
| H1-4-201 | H1-4 | P10412 | Histone H1.4 | chr6 | GO:0031490 | Not Cancer Driver | No | 33 | 0.1506849315068493 | 213 | 32 | 0.1461187214611872 | 0 |
| H1-5-201 | H1-5 | P16401 | Histone H1.5 | chr6 | GO:0031490 | Not Cancer Driver | No | 13 | 0.0575221238938053 | 226 | 13 | 0.0575221238938053 | 0 |
| H2AZ1-201 | H2AZ1 | P0C0S5 | Histone H2A.Z | chr4 | GO:0031490 | Not Cancer Driver | No | 18 | 0.140625 | 71 | 12 | 0.09375 | 0 |
| HDAC3-201 | HDAC3 | O15379 | Histone deacetylase 3 | chr5 | GO:0031490 | Not Cancer Driver | No | 42 | 0.0981308411214953 | 61 | 5 | 0.0116822429906542 | 0 |
| HNRNPU-226 | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | GO:0031490 | Not Cancer Driver | No | 57 | 0.069090909090909 | 505 | 36 | 0.0436363636363636 | 0 |
| HR-202 | HR | O43593 | Lysine-specific demethylase hairless | chr8 | GO:0031490 | Not Cancer Driver | No | 93 | 0.0782169890664424 | 592 | 53 | 0.0445752733389402 | 3 |
| HSF1-204 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0031490 | Not Cancer Driver | No | 49 | 0.0926275992438563 | 336 | 30 | 0.0567107750472589 | 0 |
| INSM1-201 | INSM1 | Q01101 | Insulinoma-associated protein 1 | chr20 | GO:0031490 | Not Cancer Driver | No | 23 | 0.0450980392156862 | 360 | 11 | 0.0215686274509803 | 0 |
| JMJD1C-202 | JMJD1C | Q15652 | Probable JmjC domain-containing histone demethylation protein 2C | chr10 | GO:0031490 | Not Cancer Driver | No | 219 | 0.0862204724409448 | 1645 | 142 | 0.0559055118110236 | 0 |
| KDM3A-201 | KDM3A | Q9Y4C1 | Lysine-specific demethylase 3A | chr2 | GO:0031490 | Not Cancer Driver | No | 93 | 0.0704012112036336 | 463 | 35 | 0.0264950794852384 | 0 |
| KDM3B-201 | KDM3B | Q7LBC6 | Lysine-specific demethylase 3B | chr5 | GO:0031490 | Compendium | Yes | 170 | 0.0965360590573537 | 946 | 82 | 0.0465644520159 | 6 |
| KDM4D-201 | KDM4D | Q6B0I6 | Lysine-specific demethylase 4D | chr11 | GO:0031490 | Not Cancer Driver | No | 66 | 0.1261950286806883 | 215 | 24 | 0.0458891013384321 | 0 |
| KDM5A-201 | KDM5A | P29375 | Lysine-specific demethylase 5A | chr12 | GO:0031490 | Census, Compendium | Yes | 153 | 0.0905325443786982 | 504 | 46 | 0.0272189349112426 | 0 |
| KDM6A-201 | KDM6A | O15550 | Lysine-specific demethylase 6A | chrX | GO:0031490 | Census, Compendium | Yes | 143 | 0.1020699500356887 | 648 | 58 | 0.0413990007137758 | 0 |
| KDM6B-202 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | GO:0031490 | Not Cancer Driver | No | 151 | 0.0919050517346317 | 1288 | 116 | 0.0706025562994522 | 2 |
| KLF4-201 | KLF4 | O43474 | Krueppel-like factor 4 | chr9 | GO:0031490 | Census, Compendium | Yes | 41 | 0.0855949895615866 | 417 | 25 | 0.0521920668058455 | 0 |
| MACROH2A1-202 | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0031490 | Not Cancer Driver | No | 31 | 0.084010840108401 | 122 | 9 | 0.024390243902439 | 0 |
| MACROH2A2-201 | MACROH2A2 | Q9P0M6 | Core histone macro-H2A.2 | chr10 | GO:0031490 | Not Cancer Driver | No | 44 | 0.1182795698924731 | 171 | 23 | 0.0618279569892473 | 0 |
| MECP2-201 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0031490 | Not Cancer Driver | No | 44 | 0.0905349794238683 | 482 | 43 | 0.088477366255144 | 32 |
| MED1-201 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0031490 | Not Cancer Driver | No | 81 | 0.0512333965844402 | 1104 | 50 | 0.0316255534471853 | 0 |
| MYOD1-201 | MYOD1 | P15172 | Myoblast determination protein 1 | chr11 | GO:0031490 | Census | Yes | 35 | 0.109375 | 246 | 26 | 0.08125 | 0 |
| MYOG-201 | MYOG | P15173 | Myogenin | chr1 | GO:0031490 | Not Cancer Driver | No | 31 | 0.1383928571428571 | 133 | 18 | 0.0803571428571428 | 0 |
| NEUROG3-201 | NEUROG3 | Q9Y4Z2 | Neurogenin-3 | chr10 | GO:0031490 | Not Cancer Driver | No | 37 | 0.1728971962616822 | 157 | 29 | 0.1355140186915887 | 2 |
| NKAP-201 | NKAP | Q8N5F7 | NF-kappa-B-activating protein | chrX | GO:0031490 | Not Cancer Driver | No | 58 | 0.1397590361445783 | 409 | 57 | 0.1373493975903614 | 2 |
| NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0031490 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
| NR1H2-201 | NR1H2 | P55055 | Oxysterols receptor LXR-beta | chr19 | GO:0031490 | Not Cancer Driver | No | 38 | 0.0826086956521739 | 180 | 16 | 0.0347826086956521 | 0 |
| NR1H3-211 | NR1H3 | Q13133 | Oxysterols receptor LXR-alpha | chr11 | GO:0031490 | Not Cancer Driver | No | 44 | 0.0984340044742729 | 147 | 13 | 0.029082774049217 | 0 |
| OGT-202 | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | GO:0031490 | Not Cancer Driver | No | 111 | 0.1061185468451242 | 90 | 9 | 0.008604206500956 | 2 |
| PAX6-203 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0031490 | Not Cancer Driver | No | 51 | 0.1208530805687203 | 338 | 37 | 0.0876777251184834 | 35 |
| PER1-201 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | GO:0031490 | Census | Yes | 128 | 0.0992248062015503 | 950 | 98 | 0.075968992248062 | 0 |
| POLE3-202 | POLE3 | Q9NRF9 | DNA polymerase epsilon subunit 3 | chr9 | GO:0031490 | Not Cancer Driver | No | 5 | 0.0340136054421768 | 117 | 5 | 0.0340136054421768 | 0 |
| PPARGC1A-201 | PPARGC1A | Q9UBK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | chr4 | GO:0031490 | Not Cancer Driver | No | 91 | 0.1140350877192982 | 613 | 85 | 0.106516290726817 | 0 |
| PRDM14-201 | PRDM14 | Q9GZV8 | PR domain zinc finger protein 14 | chr8 | GO:0031490 | Not Cancer Driver | No | 104 | 0.1821366024518388 | 180 | 31 | 0.0542907180385289 | 0 |
| RARA-201 | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0031490 | Census, Compendium | Yes | 60 | 0.1298701298701298 | 167 | 14 | 0.0303030303030303 | 0 |
| RELA-202 | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0031490 | Compendium | Yes | 53 | 0.0961887477313974 | 401 | 32 | 0.058076225045372 | 0 |
| RUNX2-212 | RUNX2 | Q13950 | Runt-related transcription factor 2 | chr6 | GO:0031490 | Not Cancer Driver | No | 50 | 0.0959692898272552 | 447 | 44 | 0.0844529750479846 | 30 |
| RUVBL2-206 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0031490 | Not Cancer Driver | No | 52 | 0.1123110151187904 | 100 | 11 | 0.0237580993520518 | 0 |
| SBNO1-203 | SBNO1 | A3KN83 | Protein strawberry notch homolog 1 | chr12 | GO:0031490 | Not Cancer Driver | No | 128 | 0.0918880114860014 | 569 | 51 | 0.0366116295764537 | 0 |
| SBNO2-201 | SBNO2 | Q9Y2G9 | Protein strawberry notch homolog 2 | chr19 | GO:0031490 | Not Cancer Driver | No | 81 | 0.0592972181551976 | 458 | 24 | 0.0175695461200585 | 0 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0031490 | Not Cancer Driver | No | 24 | 0.0676056338028169 | 165 | 6 | 0.0169014084507042 | 0 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0031490 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| SRF-201 | SRF | P11831 | Serum response factor | chr6 | GO:0031490 | Not Cancer Driver | No | 30 | 0.0590551181102362 | 443 | 29 | 0.0570866141732283 | 0 |
| STAT3-201 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0031490 | Census, Compendium | Yes | 93 | 0.1207792207792207 | 152 | 16 | 0.0207792207792207 | 15 |
| SUZ12-201 | SUZ12 | Q15022 | Polycomb protein SUZ12 | chr17 | GO:0031490 | Census, Compendium | Yes | 55 | 0.074424898511502 | 483 | 32 | 0.0433017591339648 | 3 |
| TBR1-201 | TBR1 | Q16650 | T-box brain protein 1 | chr2 | GO:0031490 | Not Cancer Driver | No | 65 | 0.095307917888563 | 413 | 42 | 0.0615835777126099 | 4 |
| THRA-201 | THRA | P10827 | Thyroid hormone receptor alpha | chr17 | GO:0031490 | Not Cancer Driver | No | 47 | 0.0959183673469387 | 207 | 21 | 0.0428571428571428 | 2 |
| THRB-216 | THRB | P10828 | Thyroid hormone receptor beta | chr3 | GO:0031490 | Not Cancer Driver | No | 61 | 0.1323210412147505 | 112 | 20 | 0.0433839479392624 | 27 |
| TOX-201 | TOX | O94900 | Thymocyte selection-associated high mobility group box protein TOX | chr8 | GO:0031490 | Not Cancer Driver | No | 83 | 0.1577946768060836 | 495 | 80 | 0.1520912547528517 | 0 |
| TOX2-202 | TOX2 | Q96NM4 | TOX high mobility group box family member 2 | chr20 | GO:0031490 | Not Cancer Driver | No | 104 | 0.2131147540983606 | 393 | 88 | 0.180327868852459 | 0 |
| TOX3-201 | TOX3 | O15405 | TOX high mobility group box family member 3 | chr16 | GO:0031490 | Not Cancer Driver | No | 52 | 0.0902777777777777 | 489 | 46 | 0.0798611111111111 | 0 |
| TOX4-203 | TOX4 | O94842 | TOX high mobility group box family member 4 | chr14 | GO:0031490 | Not Cancer Driver | No | 43 | 0.0692431561996779 | 563 | 38 | 0.0611916264090177 | 0 |
| UTY-202 | UTY | O14607 | Histone demethylase UTY | chrY | GO:0031490 | Not Cancer Driver | No | 36 | 0.0267260579064587 | 563 | 22 | 0.0163325909428359 | 0 |
| VAX1-202 | VAX1 | Q5SQQ9 | Ventral anterior homeobox 1 | chr10 | GO:0031490 | Not Cancer Driver | No | 34 | 0.1017964071856287 | 234 | 23 | 0.0688622754491018 | 1 |
| VAX2-201 | VAX2 | Q9UIW0 | Ventral anterior homeobox 2 | chr2 | GO:0031490 | Not Cancer Driver | No | 27 | 0.093103448275862 | 211 | 16 | 0.0551724137931034 | 0 |
| WBP2-201 | WBP2 | Q969T9 | WW domain-binding protein 2 | chr17 | GO:0031490 | Not Cancer Driver | No | 23 | 0.0881226053639846 | 104 | 5 | 0.0191570881226053 | 1 |
| WBP2NL-201 | WBP2NL | Q6ICG8 | Postacrosomal sheath WW domain-binding protein | chr22 | GO:0031490 | Not Cancer Driver | No | 35 | 0.1132686084142394 | 156 | 20 | 0.0647249190938511 | 0 |
| ZIC2-201 | ZIC2 | O95409 | Zinc finger protein ZIC 2 | chr13 | GO:0031490 | Not Cancer Driver | No | 37 | 0.0695488721804511 | 388 | 20 | 0.037593984962406 | 18 |