Total number of protein in "GO:0031648" GO term: 49
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BMP2-201 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0031648 | Not Cancer Driver | No | 54 | 0.1363636363636363 | 140 | 22 | 0.0555555555555555 | 0 |
| BTRC-202 | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | GO:0031648 | Not Cancer Driver | No | 57 | 0.0942148760330578 | 45 | 3 | 0.0049586776859504 | 0 |
| CAPN3-205 | CAPN3 | P20807 | Calpain-3 | chr15 | GO:0031648 | Not Cancer Driver | No | 79 | 0.0962241169305724 | 169 | 8 | 0.0097442143727162 | 46 |
| CCDC88C-203 | CCDC88C | Q9P219 | Protein Daple | chr14 | GO:0031648 | Not Cancer Driver | No | 183 | 0.0902366863905325 | 1615 | 147 | 0.0724852071005917 | 1 |
| CDC73-201 | CDC73 | Q6P1J9 | Parafibromin | chr1 | GO:0031648 | Census, Compendium | Yes | 78 | 0.1468926553672316 | 210 | 32 | 0.0602636534839924 | 2 |
| CHFR-203 | CHFR | Q96EP1 | E3 ubiquitin-protein ligase CHFR | chr12 | GO:0031648 | Not Cancer Driver | No | 59 | 0.0888554216867469 | 342 | 37 | 0.055722891566265 | 0 |
| CREBBP-201 | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0031648 | Census, Compendium | Yes | 217 | 0.0888615888615888 | 1801 | 91 | 0.0372645372645372 | 30 |
| CTSH-201 | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0031648 | Not Cancer Driver | No | 35 | 0.1044776119402985 | 4 | 0 | 0.0 | 0 |
| CUL3-201 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0031648 | Census, Compendium | Yes | 98 | 0.1276041666666666 | 168 | 18 | 0.0234375 | 3 |
| DAZAP2-201 | DAZAP2 | Q15038 | DAZ-associated protein 2 | chr12 | GO:0031648 | Not Cancer Driver | No | 11 | 0.0654761904761904 | 68 | 6 | 0.0357142857142857 | 0 |
| DERL1-201 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | GO:0031648 | Not Cancer Driver | No | 17 | 0.0677290836653386 | 12 | 0 | 0.0 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0031648 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| FBXL3-201 | FBXL3 | Q9UKT7 | F-box/LRR-repeat protein 3 | chr13 | GO:0031648 | Not Cancer Driver | No | 24 | 0.0560747663551401 | 30 | 5 | 0.0116822429906542 | 1 |
| FBXO4-201 | FBXO4 | Q9UKT5 | F-box only protein 4 | chr5 | GO:0031648 | Not Cancer Driver | No | 38 | 0.0981912144702842 | 68 | 6 | 0.0155038759689922 | 0 |
| FBXW11-201 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | GO:0031648 | Not Cancer Driver | No | 41 | 0.0756457564575645 | 20 | 2 | 0.003690036900369 | 6 |
| FBXW7-201 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0031648 | Census, Compendium | Yes | 289 | 0.4087694483734088 | 232 | 15 | 0.0212164073550212 | 17 |
| GGA3-201 | GGA3 | Q9NZ52 | ADP-ribosylation factor-binding protein GGA3 | chr17 | GO:0031648 | Not Cancer Driver | No | 51 | 0.0705394190871369 | 421 | 29 | 0.0401106500691562 | 0 |
| GSN-204 | GSN | P06396 | Gelsolin | chr9 | GO:0031648 | Not Cancer Driver | No | 51 | 0.0652173913043478 | 318 | 18 | 0.0230179028132992 | 1 |
| HDAC6-201 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0031648 | Not Cancer Driver | No | 122 | 0.1004115226337448 | 409 | 35 | 0.0288065843621399 | 0 |
| HTT-201 | HTT | P42858 | Huntingtin | chr4 | GO:0031648 | Not Cancer Driver | No | 261 | 0.0830681094844048 | 668 | 51 | 0.0162316995544239 | 2 |
| IRGM-202 | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0031648 | Not Cancer Driver | No | 7 | 0.0386740331491712 | 51 | 0 | 0.0 | 0 |
| ISOC2-202 | ISOC2 | Q96AB3 | Isochorismatase domain-containing protein 2 | chr19 | GO:0031648 | Not Cancer Driver | No | 22 | 0.1073170731707317 | 8 | 0 | 0.0 | 0 |
| KDM8-201 | KDM8 | Q8N371 | Bifunctional peptidase and arginyl-hydroxylase JMJD5 | chr16 | GO:0031648 | Not Cancer Driver | No | 32 | 0.0769230769230769 | 29 | 6 | 0.0144230769230769 | 0 |
| MDM2-224 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0031648 | Census, Compendium | Yes | 39 | 0.0794297352342158 | 298 | 24 | 0.0488798370672097 | 0 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0031648 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
| MUL1-201 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0031648 | Not Cancer Driver | No | 29 | 0.0823863636363636 | 16 | 2 | 0.0056818181818181 | 0 |
| MYLIP-202 | MYLIP | Q8WY64 | E3 ubiquitin-protein ligase MYLIP | chr6 | GO:0031648 | Not Cancer Driver | No | 41 | 0.0921348314606741 | 11 | 2 | 0.0044943820224719 | 0 |
| NR1D1-201 | NR1D1 | P20393 | Nuclear receptor subfamily 1 group D member 1 | chr17 | GO:0031648 | Not Cancer Driver | No | 56 | 0.0912052117263843 | 348 | 39 | 0.0635179153094462 | 0 |
| PEX2-201 | PEX2 | P28328 | Peroxisome biogenesis factor 2 | chr8 | GO:0031648 | Not Cancer Driver | No | 36 | 0.1180327868852459 | 5 | 1 | 0.0032786885245901 | 2 |
| PLK1-201 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | GO:0031648 | Not Cancer Driver | No | 68 | 0.1127694859038142 | 120 | 14 | 0.0232172470978441 | 0 |
| PRKDC-201 | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0031648 | Not Cancer Driver | No | 385 | 0.0932655038759689 | 421 | 43 | 0.0104166666666666 | 2 |
| PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0031648 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
| PRNP-201 | PRNP | P04156 | Major prion protein | chr20 | GO:0031648 | Not Cancer Driver | No | 28 | 0.1106719367588932 | 117 | 8 | 0.0316205533596837 | 19 |
| PYHIN1-203 | PYHIN1 | Q6K0P9 | Pyrin and HIN domain-containing protein 1 | chr1 | GO:0031648 | Not Cancer Driver | No | 139 | 0.282520325203252 | 293 | 81 | 0.1646341463414634 | 0 |
| RAD23A-203 | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | GO:0031648 | Not Cancer Driver | No | 41 | 0.1129476584022038 | 284 | 34 | 0.09366391184573 | 0 |
| RNF139-201 | RNF139 | Q8WU17 | E3 ubiquitin-protein ligase RNF139 | chr8 | GO:0031648 | Not Cancer Driver | No | 45 | 0.0677710843373494 | 68 | 3 | 0.0045180722891566 | 0 |
| RNF5-203 | RNF5 | Q99942 | E3 ubiquitin-protein ligase RNF5 | chr6 | GO:0031648 | Not Cancer Driver | No | 12 | 0.0666666666666666 | 69 | 1 | 0.0055555555555555 | 0 |
| SENP2-201 | SENP2 | Q9HC62 | Sentrin-specific protease 2 | chr3 | GO:0031648 | Not Cancer Driver | No | 41 | 0.0696095076400679 | 285 | 22 | 0.0373514431239388 | 0 |
| SERF1A-202 | SERF1B | O75920 | Small EDRK-rich factor 1 | chr5 | GO:0031648 | Not Cancer Driver | No | 0 | 0.0 | 61 | 0 | 0.0 | 0 |
| SERF1B-201 | SERF1B | O75920 | Small EDRK-rich factor 1 | chr5 | GO:0031648 | Not Cancer Driver | No | 0 | 0.0 | 61 | 0 | 0.0 | 0 |
| SERF2-201 | SERF2 | P84101 | Small EDRK-rich factor 2 | chr15 | GO:0031648 | Not Cancer Driver | No | 8 | 0.135593220338983 | 59 | 8 | 0.135593220338983 | 0 |
| SIRT1-201 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0031648 | Not Cancer Driver | No | 43 | 0.0575635876840696 | 435 | 19 | 0.0254350736278447 | 0 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0031648 | Not Cancer Driver | No | 24 | 0.0676056338028169 | 165 | 6 | 0.0169014084507042 | 0 |
| SNCA-205 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0031648 | Not Cancer Driver | No | 15 | 0.1071428571428571 | 107 | 10 | 0.0714285714285714 | 5 |
| SOX17-201 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | GO:0031648 | Compendium | Yes | 64 | 0.1545893719806763 | 379 | 45 | 0.108695652173913 | 2 |
| SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0031648 | Census | Yes | 40 | 0.0746268656716417 | 130 | 10 | 0.0186567164179104 | 1 |
| TRIM21-201 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0031648 | Not Cancer Driver | No | 63 | 0.1326315789473684 | 49 | 8 | 0.0168421052631578 | 0 |
| UTP25-202 | UTP25 | Q68CQ4 | U3 small nucleolar RNA-associated protein 25 homolog | chr1 | GO:0031648 | Not Cancer Driver | No | 76 | 0.1005291005291005 | 281 | 14 | 0.0185185185185185 | 0 |
| VPS35-201 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | GO:0031648 | Not Cancer Driver | No | 55 | 0.0690954773869346 | 99 | 7 | 0.0087939698492462 | 1 |