Total number of protein in "GO:0032355" GO term: 78
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADCYAP1R1-201 | ADCYAP1R1 | P41586 | Pituitary adenylate cyclase-activating polypeptide type I receptor | chr7 | GO:0032355 | Not Cancer Driver | No | 108 | 0.2307692307692307 | 0 | 0 | 0.0 | 0 |
ALDH1A2-201 | ALDH1A2 | O94788 | Retinal dehydrogenase 2 | chr15 | GO:0032355 | Not Cancer Driver | No | 72 | 0.138996138996139 | 56 | 12 | 0.0231660231660231 | 3 |
AREG-201 | AREG | P15514 | Amphiregulin | chr4 | GO:0032355 | Not Cancer Driver | No | 33 | 0.1309523809523809 | 152 | 26 | 0.1031746031746031 | 0 |
ARPC1B-222 | ARPC1B | O15143 | Actin-related protein 2/3 complex subunit 1B | chr7 | GO:0032355 | Not Cancer Driver | No | 28 | 0.075268817204301 | 34 | 1 | 0.0026881720430107 | 0 |
ASS1-201 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0032355 | Not Cancer Driver | No | 50 | 0.1213592233009708 | 63 | 8 | 0.0194174757281553 | 66 |
BMP7-201 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0032355 | Not Cancer Driver | No | 68 | 0.1577726218097447 | 69 | 13 | 0.0301624129930394 | 0 |
CALR-201 | CALR | P27797 | Calreticulin | chr19 | GO:0032355 | Census | Yes | 28 | 0.0671462829736211 | 245 | 16 | 0.0383693045563549 | 0 |
CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0032355 | Census | Yes | 19 | 0.0685920577617328 | 64 | 1 | 0.003610108303249 | 0 |
CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0032355 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0032355 | Census | Yes | 26 | 0.0625 | 71 | 7 | 0.016826923076923 | 0 |
CAT-201 | CAT | P04040 | Catalase | chr11 | GO:0032355 | Not Cancer Driver | No | 56 | 0.1062618595825427 | 178 | 11 | 0.0208728652751423 | 0 |
CD38-201 | CD38 | P28907 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | chr4 | GO:0032355 | Not Cancer Driver | No | 39 | 0.13 | 3 | 0 | 0.0 | 0 |
CDKN1B-201 | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0032355 | Census, Compendium | Yes | 14 | 0.0707070707070707 | 199 | 14 | 0.0707070707070707 | 0 |
COL1A1-201 | COL1A1 | P02452 | Collagen alpha-1(I) chain | chr17 | GO:0032355 | Census, Compendium | Yes | 36 | 0.0245901639344262 | 1213 | 10 | 0.0068306010928961 | 140 |
CRYAB-217 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | GO:0032355 | Not Cancer Driver | No | 17 | 0.0971428571428571 | 59 | 7 | 0.04 | 5 |
CSN1S1-201 | CSN1S1 | P47710 | Alpha-S1-casein | chr4 | GO:0032355 | Not Cancer Driver | No | 29 | 0.1567567567567567 | 109 | 16 | 0.0864864864864864 | 0 |
CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0032355 | Census, Compendium | Yes | 363 | 0.4647887323943662 | 288 | 291 | 0.3725992317541613 | 11 |
CYP19A1-201 | CYP19A1 | P11511 | Aromatase | chr15 | GO:0032355 | Not Cancer Driver | No | 63 | 0.125248508946322 | 2 | 1 | 0.0019880715705765 | 5 |
CYP1B1-205 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0032355 | Not Cancer Driver | No | 41 | 0.0755064456721915 | 33 | 3 | 0.005524861878453 | 39 |
DHH-201 | DHH | O43323 | Desert hedgehog protein | chr12 | GO:0032355 | Not Cancer Driver | No | 28 | 0.0707070707070707 | 57 | 5 | 0.0126262626262626 | 1 |
DNMT3A-202 | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | GO:0032355 | Census, Compendium | Yes | 143 | 0.156798245614035 | 372 | 44 | 0.0482456140350877 | 14 |
ERRFI1-201 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0032355 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 299 | 23 | 0.0497835497835497 | 0 |
ESR1-201 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0032355 | Census, Compendium | Yes | 92 | 0.1546218487394958 | 198 | 19 | 0.0319327731092436 | 2 |
EZH2-203 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0032355 | Census, Compendium | Yes | 74 | 0.099195710455764 | 284 | 32 | 0.0428954423592493 | 11 |
F7-202 | F7 | P08709 | Coagulation factor VII | chr13 | GO:0032355 | Not Cancer Driver | No | 56 | 0.1201716738197424 | 51 | 7 | 0.0150214592274678 | 88 |
FGF10-201 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0032355 | Not Cancer Driver | No | 42 | 0.2019230769230769 | 34 | 8 | 0.0384615384615384 | 2 |
FOXA1-201 | FOXA1 | P55317 | Hepatocyte nuclear factor 3-alpha | chr14 | GO:0032355 | Census, Compendium | Yes | 85 | 0.1800847457627118 | 295 | 44 | 0.0932203389830508 | 0 |
GH1-201 | GH1 | P01241 | Somatotropin | chr17 | GO:0032355 | Not Cancer Driver | No | 41 | 0.1889400921658986 | 24 | 7 | 0.032258064516129 | 14 |
GHSR-201 | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0032355 | Not Cancer Driver | No | 60 | 0.1639344262295081 | 4 | 0 | 0.0 | 2 |
GJB2-202 | GJB2 | P29033 | Gap junction beta-2 protein | chr13 | GO:0032355 | Not Cancer Driver | No | 25 | 0.1106194690265486 | 0 | 0 | 0.0 | 41 |
GPI-201 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | GO:0032355 | Not Cancer Driver | No | 56 | 0.1003584229390681 | 73 | 10 | 0.017921146953405 | 23 |
GPX1-202 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0032355 | Not Cancer Driver | No | 22 | 0.1083743842364532 | 12 | 3 | 0.0147783251231527 | 0 |
GPX4-201 | GPX4 | P36969 | Phospholipid hydroperoxide glutathione peroxidase | chr19 | GO:0032355 | Not Cancer Driver | No | 12 | 0.0609137055837563 | 0 | 0 | 0.0 | 0 |
GRIA1-201 | GRIA1 | P42261 | Glutamate receptor 1 | chr5 | GO:0032355 | Not Cancer Driver | No | 252 | 0.2781456953642384 | 104 | 37 | 0.0408388520971302 | 3 |
HPGD-202 | HPGD | P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | chr4 | GO:0032355 | Not Cancer Driver | No | 19 | 0.0714285714285714 | 4 | 1 | 0.0037593984962406 | 2 |
HTR5A-201 | HTR5A | P47898 | 5-hydroxytryptamine receptor 5A | chr7 | GO:0032355 | Not Cancer Driver | No | 134 | 0.3753501400560224 | 6 | 1 | 0.0028011204481792 | 0 |
IGFBP2-201 | IGFBP2 | P18065 | Insulin-like growth factor-binding protein 2 | chr2 | GO:0032355 | Not Cancer Driver | No | 24 | 0.0738461538461538 | 171 | 18 | 0.0553846153846153 | 0 |
IHH-201 | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0032355 | Not Cancer Driver | No | 50 | 0.121654501216545 | 111 | 14 | 0.0340632603406326 | 5 |
ITGAM-201 | ITGAM | P11215 | Integrin alpha-M | chr16 | GO:0032355 | Not Cancer Driver | No | 142 | 0.1232638888888889 | 133 | 9 | 0.0078125 | 0 |
KCNJ11-201 | KCNJ11 | Q14654 | ATP-sensitive inward rectifier potassium channel 11 | chr11 | GO:0032355 | Not Cancer Driver | No | 34 | 0.0871794871794871 | 20 | 1 | 0.0025641025641025 | 37 |
LEP-201 | LEP | P41159 | Leptin | chr7 | GO:0032355 | Not Cancer Driver | No | 20 | 0.1197604790419161 | 0 | 0 | 0.0 | 2 |
MAP1B-201 | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0032355 | Not Cancer Driver | No | 169 | 0.0684764991896272 | 1949 | 166 | 0.0672609400324149 | 0 |
MBD1-201 | MBD1 | Q9UIS9 | Methyl-CpG-binding domain protein 1 | chr18 | GO:0032355 | Not Cancer Driver | No | 77 | 0.1272727272727272 | 323 | 30 | 0.0495867768595041 | 0 |
MBD3-202 | MBD3 | O95983 | Methyl-CpG-binding domain protein 3 | chr19 | GO:0032355 | Not Cancer Driver | No | 38 | 0.1305841924398625 | 247 | 35 | 0.120274914089347 | 0 |
MBD4-201 | MBD4 | O95243 | Methyl-CpG-binding domain protein 4 | chr3 | GO:0032355 | Not Cancer Driver | No | 34 | 0.0586206896551724 | 268 | 11 | 0.0189655172413793 | 1 |
MECP2-201 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0032355 | Not Cancer Driver | No | 44 | 0.0905349794238683 | 482 | 43 | 0.088477366255144 | 32 |
MMP15-201 | MMP15 | P51511 | Matrix metalloproteinase-15 | chr16 | GO:0032355 | Not Cancer Driver | No | 63 | 0.0941704035874439 | 206 | 19 | 0.0284005979073243 | 0 |
NCOA1-202 | NCOA1 | Q15788 | Nuclear receptor coactivator 1 | chr2 | GO:0032355 | Census, Compendium | Yes | 135 | 0.0936849410131853 | 1217 | 107 | 0.0742539902845246 | 0 |
NCOR2-202 | NCOR2 | Q9Y618 | Nuclear receptor corepressor 2 | chr12 | GO:0032355 | Census, Compendium | Yes | 167 | 0.0664280031821798 | 2369 | 167 | 0.0664280031821798 | 0 |
NQO1-201 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | GO:0032355 | Not Cancer Driver | No | 11 | 0.0401459854014598 | 10 | 0 | 0.0 | 0 |
NR2F2-201 | NR2F2 | P24468 | COUP transcription factor 2 | chr15 | GO:0032355 | Not Cancer Driver | No | 53 | 0.1280193236714976 | 102 | 1 | 0.002415458937198 | 6 |
OGG1-205 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0032355 | Not Cancer Driver | No | 26 | 0.0753623188405797 | 72 | 4 | 0.0115942028985507 | 0 |
OPRL1-201 | OPRL1 | P41146 | Nociceptin receptor | chr20 | GO:0032355 | Not Cancer Driver | No | 70 | 0.1891891891891892 | 0 | 0 | 0.0 | 0 |
OXTR-201 | OXTR | P30559 | Oxytocin receptor | chr3 | GO:0032355 | Not Cancer Driver | No | 29 | 0.0745501285347043 | 19 | 0 | 0.0 | 0 |
PCNA-201 | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0032355 | Not Cancer Driver | No | 19 | 0.0727969348659003 | 22 | 2 | 0.0076628352490421 | 1 |
PENK-202 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0032355 | Not Cancer Driver | No | 92 | 0.3445692883895131 | 143 | 55 | 0.2059925093632958 | 0 |
POSTN-203 | POSTN | Q15063 | Periostin | chr13 | GO:0032355 | Not Cancer Driver | No | 171 | 0.2045454545454545 | 87 | 23 | 0.027511961722488 | 0 |
PTCH1-201 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0032355 | Census, Compendium | Yes | 156 | 0.1078092605390463 | 383 | 39 | 0.0269523151347615 | 17 |
PTGFR-202 | PTGFR | P43088 | Prostaglandin F2-alpha receptor | chr1 | GO:0032355 | Not Cancer Driver | No | 85 | 0.2367688022284122 | 2 | 0 | 0.0 | 0 |
PTGS2-201 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0032355 | Not Cancer Driver | No | 68 | 0.1125827814569536 | 31 | 4 | 0.0066225165562913 | 0 |
RARA-201 | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0032355 | Census, Compendium | Yes | 60 | 0.1298701298701298 | 167 | 14 | 0.0303030303030303 | 0 |
RGS9-201 | RGS9 | O75916 | Regulator of G-protein signaling 9 | chr17 | GO:0032355 | Not Cancer Driver | No | 99 | 0.1468842729970326 | 240 | 47 | 0.0697329376854599 | 1 |
SLC34A1-201 | SLC34A1 | Q06495 | Sodium-dependent phosphate transport protein 2A | chr5 | GO:0032355 | Not Cancer Driver | No | 69 | 0.107981220657277 | 46 | 8 | 0.0125195618153364 | 8 |
SLC6A1-201 | SLC6A1 | P30531 | Sodium- and chloride-dependent GABA transporter 1 | chr3 | GO:0032355 | Not Cancer Driver | No | 88 | 0.1469115191986644 | 24 | 5 | 0.008347245409015 | 4 |
SLC6A4-206 | SLC6A4 | P31645 | Sodium-dependent serotonin transporter | chr17 | GO:0032355 | Not Cancer Driver | No | 77 | 0.1222222222222222 | 76 | 7 | 0.0111111111111111 | 0 |
SOCS2-210 | SOCS2 | O14508 | Suppressor of cytokine signaling 2 | chr12 | GO:0032355 | Not Cancer Driver | No | 21 | 0.106060606060606 | 61 | 2 | 0.0101010101010101 | 0 |
STAT3-201 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0032355 | Census, Compendium | Yes | 93 | 0.1207792207792207 | 152 | 16 | 0.0207792207792207 | 15 |
STAT5B-201 | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0032355 | Census, Compendium | Yes | 73 | 0.0927573062261753 | 145 | 17 | 0.0216010165184243 | 5 |
STRN3-202 | STRN3 | Q13033 | Striatin-3 | chr14 | GO:0032355 | Not Cancer Driver | No | 62 | 0.0777917189460476 | 366 | 25 | 0.0313676286072772 | 0 |
STXBP1-201 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | GO:0032355 | Not Cancer Driver | No | 61 | 0.1026936026936027 | 112 | 13 | 0.0218855218855218 | 19 |
TACR1-201 | TACR1 | P25103 | Substance-P receptor | chr2 | GO:0032355 | Not Cancer Driver | No | 55 | 0.1351351351351351 | 28 | 2 | 0.0049140049140049 | 0 |
TACR3-201 | TACR3 | P29371 | Neuromedin-K receptor | chr4 | GO:0032355 | Not Cancer Driver | No | 116 | 0.2494623655913978 | 31 | 17 | 0.0365591397849462 | 5 |
TGFB1-201 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0032355 | Not Cancer Driver | No | 30 | 0.0769230769230769 | 44 | 3 | 0.0076923076923076 | 8 |
TH-206 | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0032355 | Not Cancer Driver | No | 48 | 0.0909090909090909 | 151 | 17 | 0.0321969696969696 | 38 |
TXNIP-204 | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | GO:0032355 | Not Cancer Driver | No | 46 | 0.1176470588235294 | 77 | 10 | 0.0255754475703324 | 0 |
UCN-201 | UCN | P55089 | Urocortin | chr2 | GO:0032355 | Not Cancer Driver | No | 7 | 0.0564516129032258 | 61 | 4 | 0.032258064516129 | 0 |
WNT7A-201 | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0032355 | Not Cancer Driver | No | 68 | 0.1948424068767908 | 18 | 6 | 0.0171919770773638 | 4 |
WNT8B-201 | WNT8B | Q93098 | Protein Wnt-8b | chr10 | GO:0032355 | Not Cancer Driver | No | 39 | 0.1111111111111111 | 27 | 4 | 0.0113960113960113 | 0 |