Total number of protein in "GO:0032436" GO term: 76
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0032436 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AURKA-208 | AURKA | O14965 | Aurora kinase A | chr20 | GO:0032436 | Not Cancer Driver | No | 25 | 0.0620347394540942 | 180 | 17 | 0.0421836228287841 | 0 |
| AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0032436 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
| AXIN2-201 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | GO:0032436 | Census, Compendium | Yes | 82 | 0.0972716488730723 | 551 | 51 | 0.0604982206405693 | 0 |
| BAG2-201 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | GO:0032436 | Not Cancer Driver | No | 13 | 0.0616113744075829 | 112 | 7 | 0.0331753554502369 | 0 |
| BBS7-201 | BBS7 | Q8IWZ6 | Bardet-Biedl syndrome 7 protein | chr4 | GO:0032436 | Not Cancer Driver | No | 69 | 0.0965034965034965 | 56 | 4 | 0.0055944055944055 | 4 |
| CBFA2T3-201 | CBFA2T3 | O75081 | Protein CBFA2T3 | chr16 | GO:0032436 | Census, Compendium | Yes | 68 | 0.1041347626339969 | 504 | 60 | 0.0918836140888208 | 0 |
| CEBPA-201 | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0032436 | Census, Compendium | Yes | 10 | 0.0279329608938547 | 343 | 10 | 0.0279329608938547 | 1 |
| CHFR-203 | CHFR | Q96EP1 | E3 ubiquitin-protein ligase CHFR | chr12 | GO:0032436 | Not Cancer Driver | No | 59 | 0.0888554216867469 | 342 | 37 | 0.055722891566265 | 0 |
| CLU-201 | CLU | P10909 | Clusterin | chr8 | GO:0032436 | Not Cancer Driver | No | 43 | 0.0957683741648107 | 157 | 18 | 0.0400890868596882 | 0 |
| COP1-204 | COP1 | Q8NHY2 | E3 ubiquitin-protein ligase COP1 | chr1 | GO:0032436 | Not Cancer Driver | No | 81 | 0.1108071135430916 | 148 | 5 | 0.0068399452804377 | 0 |
| CSNK1A1-202 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | GO:0032436 | Not Cancer Driver | No | 34 | 0.1008902077151335 | 46 | 2 | 0.0059347181008902 | 0 |
| CSNK1D-202 | CSNK1D | P48730 | Casein kinase I isoform delta | chr17 | GO:0032436 | Not Cancer Driver | No | 38 | 0.0915662650602409 | 133 | 13 | 0.0313253012048192 | 2 |
| CSNK1E-203 | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | GO:0032436 | Not Cancer Driver | No | 44 | 0.1057692307692307 | 133 | 13 | 0.03125 | 0 |
| DAB2-201 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0032436 | Not Cancer Driver | No | 108 | 0.1402597402597402 | 684 | 94 | 0.122077922077922 | 0 |
| DDA1-201 | DDA1 | Q9BW61 | DET1- and DDB1-associated protein 1 | chr19 | GO:0032436 | Not Cancer Driver | No | 6 | 0.0588235294117647 | 70 | 6 | 0.0588235294117647 | 0 |
| DDRGK1-201 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | GO:0032436 | Not Cancer Driver | No | 26 | 0.0828025477707006 | 181 | 19 | 0.0605095541401273 | 0 |
| DET1-201 | DET1 | Q7L5Y6 | DET1 homolog | chr15 | GO:0032436 | Not Cancer Driver | No | 79 | 0.1436363636363636 | 42 | 9 | 0.0163636363636363 | 0 |
| DNAJB2-201 | DNAJB2 | P25686 | DnaJ homolog subfamily B member 2 | chr2 | GO:0032436 | Not Cancer Driver | No | 39 | 0.1203703703703703 | 239 | 31 | 0.095679012345679 | 1 |
| DVL1-201 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0032436 | Not Cancer Driver | No | 42 | 0.0604316546762589 | 434 | 16 | 0.0230215827338129 | 0 |
| ELOB-203 | ELOB | Q15370 | Elongin-B | chr16 | GO:0032436 | Not Cancer Driver | No | 5 | 0.0423728813559322 | 69 | 3 | 0.0254237288135593 | 0 |
| ENST00000649547 | DET1 | Q7L5Y6 | DET1 homolog | chr15 | GO:0032436 | Not Cancer Driver | No | 79 | 0.1436363636363636 | 42 | 9 | 0.0163636363636363 | 0 |
| FBXO22-201 | FBXO22 | Q8NEZ5 | F-box only protein 22 | chr15 | GO:0032436 | Not Cancer Driver | No | 43 | 0.1066997518610421 | 15 | 1 | 0.0024813895781637 | 0 |
| FBXW8-204 | FBXW8 | Q8N3Y1 | F-box/WD repeat-containing protein 8 | chr12 | GO:0032436 | Not Cancer Driver | No | 48 | 0.0802675585284281 | 121 | 4 | 0.0066889632107023 | 0 |
| GABARAP-201 | GABARAP | O95166 | Gamma-aminobutyric acid receptor-associated protein | chr17 | GO:0032436 | Not Cancer Driver | No | 7 | 0.0598290598290598 | 12 | 0 | 0.0 | 0 |
| GBA1-202 | GBA1 | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0032436 | Not Cancer Driver | No | 60 | 0.1119402985074626 | 38 | 6 | 0.0111940298507462 | 157 |
| GCLC-214 | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0032436 | Not Cancer Driver | No | 55 | 0.086342229199372 | 167 | 15 | 0.0235478806907378 | 3 |
| GSK3A-201 | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0032436 | Not Cancer Driver | No | 33 | 0.0683229813664596 | 180 | 5 | 0.010351966873706 | 0 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0032436 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HECTD1-201 | HECTD1 | Q9ULT8 | E3 ubiquitin-protein ligase HECTD1 | chr14 | GO:0032436 | Not Cancer Driver | No | 210 | 0.0804597701149425 | 992 | 85 | 0.0325670498084291 | 0 |
| HSPA1A-201 | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0032436 | Not Cancer Driver | No | 20 | 0.0312012480499219 | 200 | 10 | 0.0156006240249609 | 0 |
| HSPA1B-201 | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0032436 | Not Cancer Driver | No | 19 | 0.0296411856474258 | 200 | 7 | 0.0109204368174727 | 0 |
| HSPBP1-202 | HSPBP1 | Q9NZL4 | Hsp70-binding protein 1 | chr19 | GO:0032436 | Not Cancer Driver | No | 26 | 0.0724233983286908 | 130 | 6 | 0.0167130919220055 | 0 |
| IL33-206 | IL33 | O95760 | Interleukin-33 | chr9 | GO:0032436 | Not Cancer Driver | No | 31 | 0.1148148148148148 | 47 | 5 | 0.0185185185185185 | 0 |
| KEAP1-201 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0032436 | Census, Compendium | Yes | 217 | 0.3477564102564102 | 57 | 7 | 0.0112179487179487 | 0 |
| KLHL40-201 | KLHL40 | Q2TBA0 | Kelch-like protein 40 | chr3 | GO:0032436 | Not Cancer Driver | No | 82 | 0.1320450885668277 | 44 | 6 | 0.0096618357487922 | 13 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0032436 | Not Cancer Driver | No | 402 | 0.1590819153146023 | 91 | 13 | 0.0051444400474871 | 20 |
| MAPK9-207 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0032436 | Not Cancer Driver | No | 37 | 0.0872641509433962 | 90 | 3 | 0.0070754716981132 | 0 |
| MDM2-224 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0032436 | Census, Compendium | Yes | 39 | 0.0794297352342158 | 298 | 24 | 0.0488798370672097 | 0 |
| NKD2-202 | NKD2 | Q969F2 | Protein naked cuticle homolog 2 | chr5 | GO:0032436 | Not Cancer Driver | No | 55 | 0.1219512195121951 | 451 | 55 | 0.1219512195121951 | 0 |
| NOP53-201 | NOP53 | Q9NZM5 | Ribosome biogenesis protein NOP53 | chr19 | GO:0032436 | Not Cancer Driver | No | 36 | 0.0753138075313807 | 399 | 26 | 0.0543933054393305 | 0 |
| NUB1-212 | NUB1 | Q9Y5A7 | NEDD8 ultimate buster 1 | chr7 | GO:0032436 | Not Cancer Driver | No | 43 | 0.0699186991869918 | 180 | 13 | 0.0211382113821138 | 0 |
| PABIR1-201 | PABIR1 | Q96E09 | PPP2R1A-PPP2R2A-interacting phosphatase regulator 1 | chr9 | GO:0032436 | Not Cancer Driver | No | 13 | 0.0452961672473867 | 285 | 13 | 0.0452961672473867 | 0 |
| PIAS1-201 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | GO:0032436 | Not Cancer Driver | No | 48 | 0.0737327188940092 | 241 | 25 | 0.0384024577572964 | 0 |
| PLK1-201 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | GO:0032436 | Not Cancer Driver | No | 68 | 0.1127694859038142 | 120 | 14 | 0.0232172470978441 | 0 |
| PRICKLE1-201 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:0032436 | Not Cancer Driver | No | 118 | 0.1419975932611311 | 485 | 71 | 0.0854392298435619 | 3 |
| PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0032436 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
| PSEN1-201 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0032436 | Not Cancer Driver | No | 43 | 0.0920770877944325 | 134 | 18 | 0.038543897216274 | 69 |
| PSMD10-201 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:0032436 | Not Cancer Driver | No | 13 | 0.0575221238938053 | 53 | 4 | 0.0176991150442477 | 0 |
| RACK1-227 | RACK1 | P63244 | Small ribosomal subunit protein RACK1 | chr5 | GO:0032436 | Not Cancer Driver | No | 27 | 0.085173501577287 | 13 | 0 | 0.0 | 0 |
| RAD23A-203 | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | GO:0032436 | Not Cancer Driver | No | 41 | 0.1129476584022038 | 284 | 34 | 0.09366391184573 | 0 |
| RBX1-201 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0032436 | Not Cancer Driver | No | 9 | 0.0833333333333333 | 18 | 1 | 0.0092592592592592 | 0 |
| RCHY1-201 | RCHY1 | Q96PM5 | RING finger and CHY zinc finger domain-containing protein 1 | chr4 | GO:0032436 | Not Cancer Driver | No | 18 | 0.0689655172413793 | 23 | 0 | 0.0 | 0 |
| RFPL1-201 | RFPL1 | O75677 | Ret finger protein-like 1 | chr22 | GO:0032436 | Not Cancer Driver | No | 44 | 0.138801261829653 | 28 | 5 | 0.0157728706624605 | 0 |
| RNF180-202 | RNF180 | Q86T96 | E3 ubiquitin-protein ligase RNF180 | chr5 | GO:0032436 | Not Cancer Driver | No | 52 | 0.0878378378378378 | 190 | 21 | 0.0354729729729729 | 0 |
| SH3RF1-201 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0032436 | Not Cancer Driver | No | 83 | 0.0934684684684684 | 588 | 55 | 0.0619369369369369 | 0 |
| SH3RF2-201 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0032436 | Not Cancer Driver | No | 125 | 0.1714677640603566 | 460 | 80 | 0.1097393689986282 | 0 |
| SH3RF3-201 | SH3RF3 | Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 | chr2 | GO:0032436 | Not Cancer Driver | No | 78 | 0.0884353741496598 | 566 | 45 | 0.0510204081632653 | 0 |
| SIRT2-201 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0032436 | Not Cancer Driver | No | 40 | 0.1028277634961439 | 85 | 13 | 0.0334190231362467 | 0 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0032436 | Not Cancer Driver | No | 24 | 0.0676056338028169 | 165 | 6 | 0.0169014084507042 | 0 |
| SMAD7-201 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0032436 | Not Cancer Driver | No | 38 | 0.0892018779342723 | 140 | 0 | 0.0 | 0 |
| SOCS4-204 | SOCS4 | Q8WXH5 | Suppressor of cytokine signaling 4 | chr14 | GO:0032436 | Not Cancer Driver | No | 28 | 0.0636363636363636 | 138 | 9 | 0.0204545454545454 | 0 |
| SOCS5-202 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0032436 | Not Cancer Driver | No | 63 | 0.1175373134328358 | 298 | 30 | 0.0559701492537313 | 0 |
| STUB1-201 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0032436 | Not Cancer Driver | No | 29 | 0.0957095709570957 | 113 | 11 | 0.0363036303630363 | 11 |
| SUMO1-203 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:0032436 | Not Cancer Driver | No | 10 | 0.099009900990099 | 76 | 7 | 0.0693069306930693 | 0 |
| SUMO2-202 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | GO:0032436 | Not Cancer Driver | No | 8 | 0.0842105263157894 | 70 | 6 | 0.0631578947368421 | 0 |
| TAF1-204 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0032436 | Not Cancer Driver | No | 278 | 0.1484249866524292 | 1174 | 156 | 0.0832888414308595 | 5 |
| TPTEP2-CSNK1E-201 | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | GO:0032436 | Not Cancer Driver | No | 44 | 0.1057692307692307 | 133 | 13 | 0.03125 | 0 |
| TRIB1-201 | TRIB1 | Q96RU8 | Tribbles homolog 1 | chr8 | GO:0032436 | Not Cancer Driver | No | 27 | 0.0725806451612903 | 91 | 4 | 0.010752688172043 | 0 |
| TRIB2-201 | TRIB2 | Q92519 | Tribbles homolog 2 | chr2 | GO:0032436 | Not Cancer Driver | No | 41 | 0.119533527696793 | 43 | 4 | 0.0116618075801749 | 0 |
| TRIB3-201 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0032436 | Not Cancer Driver | No | 45 | 0.1256983240223463 | 113 | 17 | 0.047486033519553 | 0 |
| USP5-201 | USP5 | P45974 | Ubiquitin carboxyl-terminal hydrolase 5 | chr12 | GO:0032436 | Not Cancer Driver | No | 87 | 0.1013986013986013 | 263 | 33 | 0.0384615384615384 | 0 |
| VCP-201 | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0032436 | Not Cancer Driver | No | 74 | 0.0918114143920595 | 186 | 14 | 0.0173697270471464 | 12 |
| ZER1-201 | ZER1 | Q7Z7L7 | Protein zer-1 homolog | chr9 | GO:0032436 | Not Cancer Driver | No | 63 | 0.0822454308093994 | 35 | 5 | 0.0065274151436031 | 0 |
| ZFAND2A-201 | ZFAND2A | Q8N6M9 | AN1-type zinc finger protein 2A | chr7 | GO:0032436 | Not Cancer Driver | No | 15 | 0.1034482758620689 | 9 | 0 | 0.0 | 0 |
| ZYG11B-201 | ZYG11B | Q9C0D3 | Protein zyg-11 homolog B | chr1 | GO:0032436 | Not Cancer Driver | No | 60 | 0.0806451612903225 | 30 | 6 | 0.0080645161290322 | 0 |