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Total number of protein in "GO:0032587" GO term:  103

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA7-201 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0032587 Not Cancer Driver No 171 0.0796831314072693 405 22 0.0102516309412861 1
ADAM17-201 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0032587 Not Cancer Driver No 63 0.0764563106796116 182 17 0.020631067961165 0
ADGRE2-201 ADGRE2 Q9UHX3 Adhesion G protein-coupled receptor E2 chr19 GO:0032587 Not Cancer Driver No 109 0.1324422843256379 106 18 0.0218712029161603 1
AIF1-203 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0032587 Not Cancer Driver No 12 0.0816326530612244 61 5 0.0340136054421768 0
AIF1L-201 AIF1L Q9BQI0 Allograft inflammatory factor 1-like chr9 GO:0032587 Not Cancer Driver No 6 0.04 44 1 0.0066666666666666 0
AKT2-206 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0032587 Census Yes 57 0.1185031185031185 84 9 0.0187110187110187 2
APC-201 APC P25054 Adenomatous polyposis coli protein chr5 GO:0032587 Census, Compendium Yes 295 0.1037636299683433 2412 248 0.0872317973971157 22
APPL2-201 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0032587 Not Cancer Driver No 49 0.0737951807228915 149 8 0.0120481927710843 0
ARF4-201 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0032587 Not Cancer Driver No 7 0.0388888888888888 0 0 0.0 0
ARHGAP45-201 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 GO:0032587 Not Cancer Driver No 85 0.0748239436619718 684 52 0.0457746478873239 0
ARHGEF2-203 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0032587 Not Cancer Driver No 121 0.1227180527383367 450 64 0.0649087221095334 0
ARHGEF4-201 ARHGEF4 Q9NR80 Rho guanine nucleotide exchange factor 4 chr2 GO:0032587 Not Cancer Driver No 85 0.1231884057971014 291 50 0.072463768115942 0
BMX-202 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX GO:0032587 Not Cancer Driver No 74 0.1096296296296296 172 16 0.0237037037037037 0
C2CD5-201 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 GO:0032587 Not Cancer Driver No 82 0.082 251 21 0.021 0
CDKL5-205 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0032587 Not Cancer Driver No 111 0.115625 685 79 0.0822916666666666 16
CFL1-201 CFL1 P23528 Cofilin-1 chr11 GO:0032587 Not Cancer Driver No 17 0.1024096385542168 4 0 0.0 0
CIB1-201 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0032587 Not Cancer Driver No 16 0.0837696335078534 6 1 0.0052356020942408 0
CLASP2-213 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0032587 Not Cancer Driver No 114 0.0880989180834621 677 63 0.0486862442040185 0
CLCN3-208 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0032587 Not Cancer Driver No 67 0.0819070904645476 88 4 0.0048899755501222 7
CORO1C-201 CORO1C Q9ULV4 Coronin-1C chr12 GO:0032587 Not Cancer Driver No 41 0.0864978902953586 84 12 0.0253164556962025 0
DIAPH1-201 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0032587 Not Cancer Driver No 46 0.0361635220125786 692 20 0.0157232704402515 1
DLC1-201 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0032587 Not Cancer Driver No 237 0.1551047120418848 928 169 0.1106020942408377 0
EEF1A1-201 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0032587 Not Cancer Driver No 98 0.2121212121212121 100 10 0.0216450216450216 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 GO:0032587 Census, Compendium Yes 346 0.2859504132231405 223 30 0.024793388429752 1
ENST00000560629 ITGB3 P05106 Integrin beta-3 chr17 GO:0032587 Not Cancer Driver No 92 0.1168996188055908 68 6 0.0076238881829733 27
ENST00000681750 RIGI O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0032587 Not Cancer Driver No 68 0.0777142857142857 58 5 0.0057142857142857 2
EPB41L5-201 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 GO:0032587 Not Cancer Driver No 68 0.0927694406548431 315 32 0.0436562073669849 0
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0032587 Compendium Yes 147 0.1506147540983606 188 33 0.033811475409836 3
EPS8-201 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0032587 Not Cancer Driver No 82 0.0997566909975669 461 35 0.0425790754257907 0
EPS8L1-201 EPS8L1 Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 GO:0032587 Not Cancer Driver No 69 0.0954356846473029 521 55 0.0760719225449515 0
EPS8L2-201 EPS8L2 Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 chr11 GO:0032587 Not Cancer Driver No 54 0.0755244755244755 376 25 0.0349650349650349 0
EPS8L3-202 EPS8L3 Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 chr1 GO:0032587 Not Cancer Driver No 81 0.1365935919055649 341 42 0.0708263069139966 0
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0032587 Census, Compendium Yes 249 0.198406374501992 315 32 0.0254980079681274 1
EZR-202 EZR P15311 Ezrin chr6 GO:0032587 Census Yes 51 0.0870307167235494 296 26 0.0443686006825938 0
FAM107A-201 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0032587 Not Cancer Driver No 19 0.1319444444444444 140 18 0.125 0
FAP-201 FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0032587 Not Cancer Driver No 127 0.1671052631578947 6 2 0.0026315789473684 0
FERMT1-201 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0032587 Not Cancer Driver No 75 0.1107828655834564 65 6 0.0088626292466765 2
FGD2-201 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0032587 Not Cancer Driver No 84 0.1282442748091603 160 16 0.0244274809160305 0
FGD5-201 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 GO:0032587 Compendium Yes 197 0.1347469220246238 917 134 0.0916552667578659 0
FGR-203 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0032587 Not Cancer Driver No 67 0.1266540642722117 52 6 0.0113421550094517 0
HIP1R-201 HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0032587 Not Cancer Driver No 73 0.0683520599250936 527 30 0.0280898876404494 0
IFIT5-201 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 GO:0032587 Not Cancer Driver No 31 0.0643153526970954 19 0 0.0 0
INPP5K-204 INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0032587 Not Cancer Driver No 33 0.0736607142857142 34 2 0.0044642857142857 7
ITGA5-201 ITGA5 P08648 Integrin alpha-5 chr12 GO:0032587 Not Cancer Driver No 89 0.0848427073403241 202 21 0.0200190657769304 0
ITGAV-201 ITGAV P06756 Integrin alpha-V chr2 GO:0032587 Census Yes 100 0.0954198473282442 92 8 0.0076335877862595 0
ITGB1-201 ITGB1 P05556 Integrin beta-1 chr10 GO:0032587 Not Cancer Driver No 73 0.0914786967418546 84 8 0.0100250626566416 0
ITGB3-201 ITGB3 P05106 Integrin beta-3 chr17 GO:0032587 Not Cancer Driver No 92 0.116751269035533 68 5 0.0063451776649746 28
JCAD-201 JCAD Q9P266 Junctional cadherin 5-associated protein chr10 GO:0032587 Not Cancer Driver No 228 0.1677704194260485 1347 228 0.1677704194260485 0
KANK1-205 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0032587 Not Cancer Driver No 123 0.0909763313609467 803 74 0.0547337278106508 0
KSR1-219 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 GO:0032587 Not Cancer Driver No 88 0.0948275862068965 408 46 0.0495689655172413 0
LCP1-201 LCP1 P13796 Plastin-2 chr13 GO:0032587 Census Yes 77 0.1228070175438596 73 10 0.0159489633173843 0
MACF1-204 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0032587 Not Cancer Driver No 489 0.0662153012863913 2823 185 0.0250507786052809 3
MTMR6-201 MTMR6 Q9Y217 Myotubularin-related protein 6 chr13 GO:0032587 Not Cancer Driver No 66 0.1062801932367149 69 11 0.0177133655394524 0
MTMR9-201 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0032587 Not Cancer Driver No 38 0.0692167577413479 45 4 0.0072859744990892 0
MTSS2-201 MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0032587 Not Cancer Driver No 53 0.0709504685408299 584 41 0.0548862115127175 1
MYO1C-220 MYO1C O00159 Unconventional myosin-Ic chr17 GO:0032587 Not Cancer Driver No 86 0.0809031044214487 66 9 0.0084666039510818 0
MYO6-202 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0032587 Not Cancer Driver No 92 0.0715953307392996 335 9 0.0070038910505836 3
NF2-202 NF2 P35240 Merlin chr22 GO:0032587 Census, Compendium Yes 49 0.0823529411764705 252 18 0.0302521008403361 16
NME1-203 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0032587 Not Cancer Driver No 9 0.0592105263157894 10 0 0.0 0
PACSIN1-201 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 GO:0032587 Not Cancer Driver No 41 0.0923423423423423 319 37 0.0833333333333333 0
PACSIN2-201 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 GO:0032587 Not Cancer Driver No 39 0.0802469135802469 303 19 0.0390946502057613 0
PAK1-202 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0032587 Not Cancer Driver No 36 0.0660550458715596 300 19 0.0348623853211009 2
PDE4A-203 PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:0032587 Not Cancer Driver No 90 0.1015801354401805 564 50 0.0564334085778781 0
PDE9A-201 PDE9A O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A chr21 GO:0032587 Not Cancer Driver No 73 0.1231028667790893 162 27 0.0455311973018549 0
PDPN-211 PDPN Q86YL7 Podoplanin chr1 GO:0032587 Not Cancer Driver No 30 0.1851851851851851 97 21 0.1296296296296296 0
PDXP-201 PDXP Q96GD0 Chronophin chr22 GO:0032587 Not Cancer Driver No 14 0.0472972972972973 38 4 0.0135135135135135 0
PIP5K1A-202 PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0032587 Not Cancer Driver No 53 0.094306049822064 217 22 0.0391459074733096 0
PIP5K1C-201 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0032587 Not Cancer Driver No 82 0.122754491017964 359 51 0.0763473053892215 1
PLA2G4F-202 PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0032587 Not Cancer Driver No 95 0.1118963486454652 108 4 0.0047114252061248 0
PLCG1-202 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0032587 Census, Compendium Yes 129 0.1 187 15 0.0116279069767441 0
PLCG2-206 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0032587 Not Cancer Driver No 183 0.1446640316205533 144 18 0.0142292490118577 1
PLEK-201 PLEK P08567 Pleckstrin chr2 GO:0032587 Not Cancer Driver No 55 0.1571428571428571 39 5 0.0142857142857142 0
PLEKHA1-203 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0032587 Not Cancer Driver No 48 0.1188118811881188 192 28 0.0693069306930693 0
PLEKHO1-201 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 GO:0032587 Not Cancer Driver No 44 0.1075794621026894 343 36 0.0880195599022004 0
PPP1R9B-202 PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0032587 Not Cancer Driver No 37 0.0452876376988984 698 27 0.033047735618115 0
PSD-201 PSD A5PKW4 PH and SEC7 domain-containing protein 1 chr10 GO:0032587 Not Cancer Driver No 149 0.1455078125 716 119 0.1162109375 0
PSD2-201 PSD2 Q9BQI7 PH and SEC7 domain-containing protein 2 chr5 GO:0032587 Not Cancer Driver No 107 0.1387808041504539 402 61 0.0791180285343709 0
PSD3-202 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 GO:0032587 Not Cancer Driver No 86 0.0821394460362941 650 56 0.0534861509073543 0
PSD4-201 PSD4 Q8NDX1 PH and SEC7 domain-containing protein 4 chr2 GO:0032587 Not Cancer Driver No 128 0.1212121212121212 742 86 0.0814393939393939 0
PTPRJ-201 PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0032587 Not Cancer Driver No 130 0.0972326103216155 403 39 0.0291697830964846 0
RAB34-204 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 GO:0032587 Not Cancer Driver No 29 0.1119691119691119 1 0 0.0 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0032587 Census, Compendium Yes 61 0.3177083333333333 2 0 0.0 6
RASGRP2-211 RASGRP2 Q7LDG7 RAS guanyl-releasing protein 2 chr11 GO:0032587 Not Cancer Driver No 76 0.1247947454844006 88 11 0.0180623973727422 4
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 GO:0032587 Census, Compendium Yes 92 0.4766839378238341 46 12 0.0621761658031088 2
RIGI-202 RIGI O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0032587 Not Cancer Driver No 78 0.0843243243243243 61 6 0.0064864864864864 2
RPS3-217 RPS3 P23396 Small ribosomal subunit protein uS3 chr11 GO:0032587 Not Cancer Driver No 22 0.0905349794238683 48 4 0.0164609053497942 0
SH2D3C-201 SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0032587 Not Cancer Driver No 81 0.0941860465116279 443 52 0.0604651162790697 0
SH3BGRL3-201 SH3BGRL3 Q9H299 SH3 domain-binding glutamic acid-rich-like protein 3 chr1 GO:0032587 Not Cancer Driver No 7 0.075268817204301 34 3 0.032258064516129 0
SH3YL1-201 SH3YL1 Q96HL8 SH3 domain-containing YSC84-like protein 1 chr2 GO:0032587 Not Cancer Driver No 27 0.0789473684210526 109 9 0.0263157894736842 0
SNTG1-213 SNTG1 Q9NSN8 Gamma-1-syntrophin chr8 GO:0032587 Not Cancer Driver No 172 0.3326885880077369 3 1 0.0019342359767891 0
SPATA13-202 SPATA13 Q96N96 Spermatogenesis-associated protein 13 chr13 GO:0032587 Not Cancer Driver No 46 0.0705521472392638 264 22 0.0337423312883435 0
SPRY2-202 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0032587 Not Cancer Driver No 32 0.1015873015873015 170 19 0.0603174603174603 1
SPRY4-202 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0032587 Not Cancer Driver No 32 0.1070234113712374 134 17 0.0568561872909698 7
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0032587 Census Yes 40 0.0746268656716417 130 10 0.0186567164179104 1
TESC-201 TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0032587 Not Cancer Driver No 21 0.0981308411214953 73 6 0.02803738317757 0
THEM4-201 THEM4 Q5T1C6 Acyl-coenzyme A thioesterase THEM4 chr1 GO:0032587 Not Cancer Driver No 12 0.05 14 0 0.0 0
TIAM1-206 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0032587 Not Cancer Driver No 263 0.1653048397234443 813 147 0.092394720301697 0
TIRAP-202 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0032587 Not Cancer Driver No 14 0.0633484162895927 80 5 0.0226244343891402 0
TLN1-201 TLN1 Q9Y490 Talin-1 chr9 GO:0032587 Not Cancer Driver No 211 0.0830381739472648 1110 90 0.0354191263282172 0
TPM1-207 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0032587 Not Cancer Driver No 21 0.0739436619718309 236 18 0.0633802816901408 7
TRPV4-201 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0032587 Not Cancer Driver No 109 0.1251435132032147 232 30 0.0344431687715269 38
TWF1-201 TWF1 Q12792 Twinfilin-1 chr12 GO:0032587 Not Cancer Driver No 25 0.0714285714285714 52 1 0.0028571428571428 0
WWC1-201 WWC1 Q8IX03 Protein KIBRA chr5 GO:0032587 Not Cancer Driver No 120 0.1078167115902965 555 70 0.0628930817610062 0