Total number of protein in "GO:0032869" GO term: 93
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADIPOQ-201 | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0032869 | Not Cancer Driver | No | 32 | 0.1311475409836065 | 92 | 16 | 0.0655737704918032 | 1 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0032869 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AKT2-206 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0032869 | Census | Yes | 57 | 0.1185031185031185 | 84 | 9 | 0.0187110187110187 | 2 |
| BGLAP-201 | BGLAP | P02818 | Osteocalcin | chr1 | GO:0032869 | Not Cancer Driver | No | 6 | 0.06 | 21 | 0 | 0.0 | 0 |
| CAPN10-207 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | GO:0032869 | Not Cancer Driver | No | 63 | 0.09375 | 53 | 5 | 0.0074404761904761 | 0 |
| CEACAM1-201 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:0032869 | Not Cancer Driver | No | 42 | 0.0798479087452471 | 242 | 14 | 0.026615969581749 | 0 |
| CFLAR-201 | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0032869 | Not Cancer Driver | No | 31 | 0.0645833333333333 | 44 | 1 | 0.0020833333333333 | 0 |
| CPEB1-219 | CPEB1 | Q9BZB8 | Cytoplasmic polyadenylation element-binding protein 1 | chr15 | GO:0032869 | Not Cancer Driver | No | 64 | 0.1088435374149659 | 221 | 26 | 0.0442176870748299 | 0 |
| CYFIP1-208 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0032869 | Not Cancer Driver | No | 121 | 0.0965682362330407 | 95 | 5 | 0.0039904229848363 | 0 |
| DENND4C-209 | DENND4C | Q5VZ89 | DENN domain-containing protein 4C | chr9 | GO:0032869 | Not Cancer Driver | No | 121 | 0.0633839706652697 | 709 | 40 | 0.0209533787323205 | 0 |
| EEF2K-201 | EEF2K | O00418 | Eukaryotic elongation factor 2 kinase | chr16 | GO:0032869 | Not Cancer Driver | No | 80 | 0.1103448275862069 | 311 | 30 | 0.0413793103448275 | 0 |
| ENPP1-204 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0032869 | Not Cancer Driver | No | 114 | 0.1232432432432432 | 101 | 3 | 0.0032432432432432 | 32 |
| ENST00000498285 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | GO:0032869 | Not Cancer Driver | No | 3 | 0.024793388429752 | 60 | 1 | 0.0082644628099173 | 3 |
| ENST00000593731 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0032869 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| ENST00000648869 | RAB13 | P51153 | Ras-related protein Rab-13 | chr1 | GO:0032869 | Not Cancer Driver | No | 10 | 0.0492610837438423 | 41 | 0 | 0.0 | 0 |
| EPRS1-201 | EPRS1 | P07814 | Bifunctional glutamate/proline--tRNA ligase | chr1 | GO:0032869 | Not Cancer Driver | No | 151 | 0.0998677248677248 | 373 | 38 | 0.0251322751322751 | 1 |
| FBP1-201 | FBP1 | P09467 | Fructose-1,6-bisphosphatase 1 | chr9 | GO:0032869 | Not Cancer Driver | No | 24 | 0.0710059171597633 | 19 | 0 | 0.0 | 4 |
| FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0032869 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
| GCK-204 | GCK | P35557 | Hexokinase-4 | chr7 | GO:0032869 | Not Cancer Driver | No | 72 | 0.1548387096774193 | 73 | 12 | 0.0258064516129032 | 98 |
| GCLC-214 | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0032869 | Not Cancer Driver | No | 55 | 0.086342229199372 | 167 | 15 | 0.0235478806907378 | 3 |
| GHR-201 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0032869 | Not Cancer Driver | No | 139 | 0.2178683385579937 | 229 | 59 | 0.0924764890282131 | 19 |
| GHRHR-201 | GHRHR | Q02643 | Growth hormone-releasing hormone receptor | chr7 | GO:0032869 | Not Cancer Driver | No | 30 | 0.0709219858156028 | 3 | 0 | 0.0 | 5 |
| GHSR-201 | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0032869 | Not Cancer Driver | No | 60 | 0.1639344262295081 | 4 | 0 | 0.0 | 2 |
| GOT1-201 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | GO:0032869 | Not Cancer Driver | No | 36 | 0.0871670702179176 | 35 | 5 | 0.0121065375302663 | 0 |
| GPLD1-201 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0032869 | Not Cancer Driver | No | 117 | 0.1392857142857143 | 37 | 7 | 0.0083333333333333 | 0 |
| GPT-202 | GPT | P24298 | Alanine aminotransferase 1 | chr8 | GO:0032869 | Not Cancer Driver | No | 43 | 0.0866935483870967 | 51 | 5 | 0.0100806451612903 | 0 |
| GSK3A-201 | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0032869 | Not Cancer Driver | No | 33 | 0.0683229813664596 | 180 | 5 | 0.010351966873706 | 0 |
| HDAC5-213 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | GO:0032869 | Not Cancer Driver | No | 93 | 0.0828877005347593 | 720 | 61 | 0.0543672014260249 | 0 |
| HDAC9-212 | HDAC9 | Q9UKV0 | Histone deacetylase 9 | chr7 | GO:0032869 | Not Cancer Driver | No | 222 | 0.2195845697329377 | 631 | 140 | 0.1384767556874381 | 0 |
| HMGCS2-201 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0032869 | Not Cancer Driver | No | 65 | 0.1279527559055118 | 29 | 2 | 0.0039370078740157 | 19 |
| INHBB-201 | INHBB | P09529 | Inhibin beta B chain | chr2 | GO:0032869 | Not Cancer Driver | No | 40 | 0.0982800982800982 | 98 | 2 | 0.0049140049140049 | 0 |
| INPP5K-204 | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0032869 | Not Cancer Driver | No | 33 | 0.0736607142857142 | 34 | 2 | 0.0044642857142857 | 7 |
| INSIG1-201 | INSIG1 | O15503 | Insulin-induced gene 1 protein | chr7 | GO:0032869 | Not Cancer Driver | No | 25 | 0.0902527075812274 | 43 | 1 | 0.003610108303249 | 0 |
| INSIG2-201 | INSIG2 | Q9Y5U4 | Insulin-induced gene 2 protein | chr2 | GO:0032869 | Not Cancer Driver | No | 27 | 0.12 | 11 | 3 | 0.0133333333333333 | 0 |
| INSR-201 | INSR | P06213 | Insulin receptor | chr19 | GO:0032869 | Not Cancer Driver | No | 139 | 0.1005788712011577 | 282 | 37 | 0.0267727930535455 | 63 |
| IRS1-201 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0032869 | Not Cancer Driver | No | 118 | 0.0950080515297906 | 1075 | 104 | 0.0837359098228663 | 2 |
| IRS2-201 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0032869 | Not Cancer Driver | No | 44 | 0.0328849028400597 | 1117 | 34 | 0.0254110612855007 | 0 |
| KAT2B-201 | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0032869 | Not Cancer Driver | No | 78 | 0.09375 | 268 | 20 | 0.0240384615384615 | 0 |
| LEP-201 | LEP | P41159 | Leptin | chr7 | GO:0032869 | Not Cancer Driver | No | 20 | 0.1197604790419161 | 0 | 0 | 0.0 | 2 |
| LPIN1-201 | LPIN1 | Q14693 | Phosphatidate phosphatase LPIN1 | chr2 | GO:0032869 | Not Cancer Driver | No | 88 | 0.098876404494382 | 449 | 52 | 0.0584269662921348 | 0 |
| LPIN2-204 | LPIN2 | Q92539 | Phosphatidate phosphatase LPIN2 | chr18 | GO:0032869 | Not Cancer Driver | No | 93 | 0.1037946428571428 | 455 | 51 | 0.0569196428571428 | 1 |
| LPIN3-201 | LPIN3 | Q9BQK8 | Phosphatidate phosphatase LPIN3 | chr20 | GO:0032869 | Not Cancer Driver | No | 75 | 0.0881316098707403 | 473 | 39 | 0.0458284371327849 | 0 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0032869 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
| MYO5A-204 | MYO5A | Q9Y4I1 | Unconventional myosin-Va | chr15 | GO:0032869 | Census, Compendium | Yes | 159 | 0.0857142857142857 | 499 | 53 | 0.0285714285714285 | 0 |
| OTOP1-201 | OTOP1 | Q7RTM1 | Proton channel OTOP1 | chr4 | GO:0032869 | Not Cancer Driver | No | 81 | 0.1323529411764706 | 90 | 7 | 0.011437908496732 | 0 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PAX6-203 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0032869 | Not Cancer Driver | No | 51 | 0.1208530805687203 | 338 | 37 | 0.0876777251184834 | 35 |
| PCK1-201 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0032869 | Not Cancer Driver | No | 112 | 0.180064308681672 | 111 | 24 | 0.0385852090032154 | 1 |
| PCK2-201 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | GO:0032869 | Not Cancer Driver | No | 65 | 0.1015625 | 139 | 9 | 0.0140625 | 0 |
| PCSK9-201 | PCSK9 | Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | chr1 | GO:0032869 | Not Cancer Driver | No | 73 | 0.1054913294797687 | 150 | 20 | 0.0289017341040462 | 8 |
| PDE3B-201 | PDE3B | Q13370 | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B | chr11 | GO:0032869 | Not Cancer Driver | No | 101 | 0.0908273381294964 | 394 | 24 | 0.0215827338129496 | 0 |
| PDPK1-202 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0032869 | Not Cancer Driver | No | 23 | 0.0413669064748201 | 121 | 9 | 0.0161870503597122 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0032869 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0032869 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PIK3R2-201 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0032869 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| PKLR-201 | PKLR | P30613 | Pyruvate kinase PKLR | chr1 | GO:0032869 | Not Cancer Driver | No | 93 | 0.1620209059233449 | 26 | 5 | 0.0087108013937282 | 86 |
| PKM-202 | PKM | P14618 | Pyruvate kinase PKM | chr15 | GO:0032869 | Not Cancer Driver | No | 53 | 0.0998116760828625 | 58 | 11 | 0.0207156308851224 | 0 |
| PLA2G1B-201 | PLA2G1B | P04054 | Phospholipase A2 | chr12 | GO:0032869 | Not Cancer Driver | No | 10 | 0.0675675675675675 | 0 | 0 | 0.0 | 0 |
| PNPLA3-201 | PNPLA3 | Q9NST1 | 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 | chr22 | GO:0032869 | Not Cancer Driver | No | 38 | 0.079002079002079 | 33 | 7 | 0.0145530145530145 | 0 |
| POU4F2-201 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0032869 | Not Cancer Driver | No | 96 | 0.2347188264058679 | 311 | 64 | 0.1564792176039119 | 0 |
| PPARG-201 | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0032869 | Census | Yes | 60 | 0.1188118811881188 | 44 | 3 | 0.0059405940594059 | 3 |
| PRKCI-201 | PRKCI | P41743 | Protein kinase C iota type | chr3 | GO:0032869 | Not Cancer Driver | No | 79 | 0.1325503355704698 | 120 | 12 | 0.0201342281879194 | 0 |
| PRKCZ-201 | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | GO:0032869 | Not Cancer Driver | No | 47 | 0.0793918918918918 | 117 | 11 | 0.018581081081081 | 0 |
| PRKDC-201 | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0032869 | Not Cancer Driver | No | 385 | 0.0932655038759689 | 421 | 43 | 0.0104166666666666 | 2 |
| RAB10-201 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | GO:0032869 | Not Cancer Driver | No | 12 | 0.06 | 28 | 1 | 0.005 | 0 |
| RAB13-201 | RAB13 | P51153 | Ras-related protein Rab-13 | chr1 | GO:0032869 | Not Cancer Driver | No | 10 | 0.0492610837438423 | 40 | 0 | 0.0 | 0 |
| RAB31-207 | RAB31 | Q13636 | Ras-related protein Rab-31 | chr18 | GO:0032869 | Not Cancer Driver | No | 18 | 0.0923076923076923 | 28 | 7 | 0.0358974358974358 | 0 |
| RAB8A-201 | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | GO:0032869 | Not Cancer Driver | No | 30 | 0.144927536231884 | 26 | 3 | 0.0144927536231884 | 0 |
| RB1-201 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0032869 | Census, Compendium | Yes | 89 | 0.0959051724137931 | 282 | 26 | 0.0280172413793103 | 21 |
| RHOQ-201 | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | GO:0032869 | Not Cancer Driver | No | 19 | 0.0926829268292682 | 0 | 0 | 0.0 | 0 |
| RPS6KB1-201 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0032869 | Not Cancer Driver | No | 36 | 0.0685714285714285 | 226 | 22 | 0.0419047619047619 | 0 |
| SELENOS-203 | SELENOS | Q9BQE4 | Selenoprotein S | chr15 | GO:0032869 | Not Cancer Driver | No | 4 | 0.0211640211640211 | 123 | 3 | 0.0158730158730158 | 0 |
| SLC22A12-204 | SLC22A12 | Q96S37 | Solute carrier family 22 member 12 | chr11 | GO:0032869 | Not Cancer Driver | No | 77 | 0.1392405063291139 | 10 | 2 | 0.0036166365280289 | 10 |
| SLC25A33-201 | SLC25A33 | Q9BSK2 | Solute carrier family 25 member 33 | chr1 | GO:0032869 | Not Cancer Driver | No | 21 | 0.0654205607476635 | 4 | 0 | 0.0 | 0 |
| SLC2A4-201 | SLC2A4 | P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | chr17 | GO:0032869 | Not Cancer Driver | No | 47 | 0.0923379174852652 | 44 | 6 | 0.0117878192534381 | 1 |
| SLC39A14-204 | SLC39A14 | Q15043 | Metal cation symporter ZIP14 | chr8 | GO:0032869 | Not Cancer Driver | No | 27 | 0.0548780487804878 | 42 | 3 | 0.0060975609756097 | 4 |
| SLC9A1-201 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 57 | 0.0699386503067484 | 252 | 17 | 0.0208588957055214 | 1 |
| SORBS1-211 | SORBS1 | Q9BX66 | Sorbin and SH3 domain-containing protein 1 | chr10 | GO:0032869 | Not Cancer Driver | No | 123 | 0.0952012383900928 | 1116 | 101 | 0.0781733746130031 | 0 |
| SP1-201 | SP1 | P08047 | Transcription factor Sp1 | chr12 | GO:0032869 | Not Cancer Driver | No | 67 | 0.0853503184713375 | 601 | 53 | 0.0675159235668789 | 0 |
| SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0032869 | Census | Yes | 40 | 0.0746268656716417 | 130 | 10 | 0.0186567164179104 | 1 |
| SRD5A1-201 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0032869 | Not Cancer Driver | No | 26 | 0.1003861003861003 | 0 | 0 | 0.0 | 0 |
| STAT1-201 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0032869 | Not Cancer Driver | No | 100 | 0.1333333333333333 | 144 | 16 | 0.0213333333333333 | 23 |
| SYAP1-201 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | GO:0032869 | Not Cancer Driver | No | 20 | 0.0568181818181818 | 221 | 15 | 0.0426136363636363 | 0 |
| TBC1D4-202 | TBC1D4 | O60343 | TBC1 domain family member 4 | chr13 | GO:0032869 | Not Cancer Driver | No | 120 | 0.0924499229583975 | 594 | 64 | 0.049306625577812 | 0 |
| TRARG1-201 | TRARG1 | Q8IXB3 | Trafficking regulator of GLUT4 1 | chr17 | GO:0032869 | Not Cancer Driver | No | 26 | 0.1468926553672316 | 85 | 10 | 0.0564971751412429 | 0 |
| TRIB3-201 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0032869 | Not Cancer Driver | No | 45 | 0.1256983240223463 | 113 | 17 | 0.047486033519553 | 0 |
| UCP2-211 | UCP2 | P55851 | Dicarboxylate carrier SLC25A8 | chr11 | GO:0032869 | Not Cancer Driver | No | 23 | 0.0744336569579288 | 12 | 4 | 0.0129449838187702 | 0 |
| USF1-203 | USF1 | P22415 | Upstream stimulatory factor 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 28 | 0.0903225806451612 | 271 | 27 | 0.0870967741935483 | 0 |
| VAMP2-201 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | GO:0032869 | Not Cancer Driver | No | 3 | 0.0258620689655172 | 47 | 0 | 0.0 | 3 |
| WDTC1-201 | WDTC1 | Q8N5D0 | WD and tetratricopeptide repeats protein 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 66 | 0.0974889217134416 | 154 | 19 | 0.0280649926144756 | 0 |
| XBP1-201 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0032869 | Not Cancer Driver | No | 11 | 0.0421455938697318 | 171 | 6 | 0.0229885057471264 | 0 |
| YWHAG-201 | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | GO:0032869 | Not Cancer Driver | No | 21 | 0.0850202429149797 | 78 | 4 | 0.0161943319838056 | 3 |
| ZFP36L1-202 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0032869 | Compendium | Yes | 50 | 0.1479289940828402 | 212 | 26 | 0.0769230769230769 | 0 |