Total number of protein in "GO:0032956" GO term: 91
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0032956 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
ABL2-203 | ABL2 | P42684 | Tyrosine-protein kinase ABL2 | chr1 | GO:0032956 | Census, Compendium | Yes | 125 | 0.1057529610829103 | 644 | 53 | 0.0448392554991539 | 0 |
ARHGAP17-201 | ARHGAP17 | Q68EM7 | Rho GTPase-activating protein 17 | chr16 | GO:0032956 | Not Cancer Driver | No | 68 | 0.0771850170261067 | 547 | 35 | 0.039727582292849 | 0 |
ARHGAP18-201 | ARHGAP18 | Q8N392 | Rho GTPase-activating protein 18 | chr6 | GO:0032956 | Not Cancer Driver | No | 59 | 0.0889894419306184 | 297 | 23 | 0.0346907993966817 | 0 |
ARHGAP35-205 | ARHGAP35 | Q9NRY4 | Rho GTPase-activating protein 35 | chr19 | GO:0032956 | Census, Compendium | Yes | 192 | 0.1280853902601734 | 410 | 43 | 0.028685790527018 | 0 |
ARHGAP44-203 | ARHGAP44 | Q17R89 | Rho GTPase-activating protein 44 | chr17 | GO:0032956 | Not Cancer Driver | No | 105 | 0.128361858190709 | 427 | 56 | 0.0684596577017114 | 0 |
ARHGEF19-201 | ARHGEF19 | Q8IW93 | Rho guanine nucleotide exchange factor 19 | chr1 | GO:0032956 | Not Cancer Driver | No | 64 | 0.0798004987531172 | 366 | 30 | 0.0374064837905236 | 0 |
ARHGEF5-201 | ARHGEF5 | Q12774 | Rho guanine nucleotide exchange factor 5 | chr7 | GO:0032956 | Not Cancer Driver | No | 122 | 0.0763932373199749 | 1141 | 89 | 0.0557294927989981 | 0 |
BAIAP2-202 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | GO:0032956 | Not Cancer Driver | No | 60 | 0.108695652173913 | 332 | 43 | 0.0778985507246376 | 0 |
BAIAP2L1-201 | BAIAP2L1 | Q9UHR4 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 | chr7 | GO:0032956 | Not Cancer Driver | No | 52 | 0.1017612524461839 | 294 | 29 | 0.0567514677103718 | 0 |
BCAS3-201 | BCAS3 | Q9H6U6 | BCAS3 microtubule associated cell migration factor | chr17 | GO:0032956 | Not Cancer Driver | No | 94 | 0.1012931034482758 | 419 | 47 | 0.0506465517241379 | 2 |
BST1-201 | BST1 | Q10588 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | chr4 | GO:0032956 | Not Cancer Driver | No | 29 | 0.0911949685534591 | 11 | 0 | 0.0 | 0 |
BST2-201 | BST2 | Q10589 | Bone marrow stromal antigen 2 | chr19 | GO:0032956 | Not Cancer Driver | No | 10 | 0.0555555555555555 | 20 | 0 | 0.0 | 0 |
CAPN10-207 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | GO:0032956 | Not Cancer Driver | No | 63 | 0.09375 | 53 | 5 | 0.0074404761904761 | 0 |
CCDC88A-207 | CCDC88A | Q3V6T2 | Girdin | chr2 | GO:0032956 | Not Cancer Driver | No | 145 | 0.0774986638161411 | 1481 | 114 | 0.0609299839657936 | 0 |
CD2AP-201 | CD2AP | Q9Y5K6 | CD2-associated protein | chr6 | GO:0032956 | Not Cancer Driver | No | 51 | 0.0798122065727699 | 458 | 38 | 0.0594679186228482 | 0 |
CDC42-208 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0032956 | Not Cancer Driver | No | 21 | 0.1099476439790576 | 23 | 1 | 0.0052356020942408 | 1 |
CDK10-202 | CDK10 | Q15131 | Cyclin-dependent kinase 10 | chr16 | GO:0032956 | Not Cancer Driver | No | 36 | 0.1 | 30 | 6 | 0.0166666666666666 | 0 |
CDK5R1-201 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0032956 | Not Cancer Driver | No | 29 | 0.0944625407166123 | 103 | 10 | 0.0325732899022801 | 0 |
CELSR1-201 | CELSR1 | Q9NYQ6 | Cadherin EGF LAG seven-pass G-type receptor 1 | chr22 | GO:0032956 | Not Cancer Driver | No | 300 | 0.099535500995355 | 890 | 75 | 0.0248838752488387 | 4 |
CORO1A-201 | CORO1A | P31146 | Coronin-1A | chr16 | GO:0032956 | Not Cancer Driver | No | 39 | 0.0845986984815618 | 126 | 11 | 0.0238611713665943 | 1 |
CORO2B-201 | CORO2B | Q9UQ03 | Coronin-2B | chr15 | GO:0032956 | Not Cancer Driver | No | 69 | 0.14375 | 37 | 5 | 0.0104166666666666 | 0 |
CRK-201 | CRK | P46108 | Adapter molecule crk | chr17 | GO:0032956 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 197 | 19 | 0.0625 | 0 |
CSF1R-210 | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0032956 | Census | Yes | 101 | 0.1039094650205761 | 124 | 12 | 0.0123456790123456 | 20 |
DAAM2-201 | DAAM2 | Q86T65 | Disheveled-associated activator of morphogenesis 2 | chr6 | GO:0032956 | Not Cancer Driver | No | 146 | 0.1367041198501872 | 273 | 47 | 0.0440074906367041 | 0 |
DAPK3-202 | DAPK3 | O43293 | Death-associated protein kinase 3 | chr19 | GO:0032956 | Not Cancer Driver | No | 45 | 0.0991189427312775 | 82 | 6 | 0.013215859030837 | 0 |
DIXDC1-201 | DIXDC1 | Q155Q3 | Dixin | chr11 | GO:0032956 | Not Cancer Driver | No | 55 | 0.0805270863836017 | 498 | 44 | 0.0644216691068814 | 0 |
DLC1-201 | DLC1 | Q96QB1 | Rho GTPase-activating protein 7 | chr8 | GO:0032956 | Not Cancer Driver | No | 237 | 0.1551047120418848 | 928 | 169 | 0.1106020942408377 | 0 |
DMTN-202 | DMTN | Q08495 | Dematin | chr8 | GO:0032956 | Not Cancer Driver | No | 45 | 0.1111111111111111 | 348 | 39 | 0.0962962962962963 | 0 |
DVL2-201 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0032956 | Not Cancer Driver | No | 72 | 0.0978260869565217 | 515 | 52 | 0.0706521739130434 | 0 |
DVL3-201 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0032956 | Not Cancer Driver | No | 58 | 0.0810055865921787 | 437 | 31 | 0.0432960893854748 | 0 |
EFNA5-201 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0032956 | Not Cancer Driver | No | 24 | 0.1052631578947368 | 25 | 6 | 0.0263157894736842 | 0 |
ENST00000560629 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0032956 | Not Cancer Driver | No | 92 | 0.1168996188055908 | 68 | 6 | 0.0076238881829733 | 27 |
ENST00000695856 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0032956 | Not Cancer Driver | No | 21 | 0.1099476439790576 | 23 | 1 | 0.0052356020942408 | 1 |
EPHA3-201 | EPHA3 | P29320 | Ephrin type-A receptor 3 | chr3 | GO:0032956 | Census, Compendium | Yes | 285 | 0.2899287894201424 | 74 | 26 | 0.0264496439471007 | 0 |
EPHA5-201 | EPHA5 | P54756 | Ephrin type-A receptor 5 | chr4 | GO:0032956 | Not Cancer Driver | No | 296 | 0.2854387656702025 | 84 | 24 | 0.0231436837029893 | 0 |
ESAM-201 | ESAM | Q96AP7 | Endothelial cell-selective adhesion molecule | chr11 | GO:0032956 | Not Cancer Driver | No | 37 | 0.0948717948717948 | 155 | 22 | 0.0564102564102564 | 0 |
EZR-202 | EZR | P15311 | Ezrin | chr6 | GO:0032956 | Census | Yes | 51 | 0.0870307167235494 | 296 | 26 | 0.0443686006825938 | 0 |
F11R-202 | F11R | Q9Y624 | Junctional adhesion molecule A | chr1 | GO:0032956 | Not Cancer Driver | No | 42 | 0.1404682274247491 | 72 | 12 | 0.040133779264214 | 0 |
FAM107A-201 | FAM107A | O95990 | Actin-associated protein FAM107A | chr3 | GO:0032956 | Not Cancer Driver | No | 19 | 0.1319444444444444 | 140 | 18 | 0.125 | 0 |
FSCN1-201 | FSCN1 | Q16658 | Fascin | chr7 | GO:0032956 | Not Cancer Driver | No | 44 | 0.0892494929006085 | 81 | 5 | 0.0101419878296146 | 0 |
FZD10-201 | FZD10 | Q9ULW2 | Frizzled-10 | chr12 | GO:0032956 | Not Cancer Driver | No | 111 | 0.1910499139414802 | 65 | 13 | 0.0223752151462994 | 0 |
GPM6B-203 | GPM6B | Q13491 | Neuronal membrane glycoprotein M6-b | chrX | GO:0032956 | Not Cancer Driver | No | 26 | 0.0981132075471698 | 14 | 3 | 0.0113207547169811 | 0 |
GRHL3-202 | GRHL3 | Q8TE85 | Grainyhead-like protein 3 homolog | chr1 | GO:0032956 | Not Cancer Driver | No | 66 | 0.1054313099041533 | 294 | 36 | 0.0575079872204472 | 3 |
HCK-202 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0032956 | Not Cancer Driver | No | 89 | 0.1692015209125475 | 124 | 22 | 0.0418250950570342 | 0 |
HIP1R-201 | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0032956 | Not Cancer Driver | No | 73 | 0.0683520599250936 | 527 | 30 | 0.0280898876404494 | 0 |
HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | GO:0032956 | Census, Compendium | Yes | 129 | 0.6825396825396826 | 16 | 2 | 0.0105820105820105 | 10 |
HRG-201 | HRG | P04196 | Histidine-rich glycoprotein | chr3 | GO:0032956 | Not Cancer Driver | No | 83 | 0.1580952380952381 | 283 | 57 | 0.1085714285714285 | 2 |
IL1A-201 | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0032956 | Not Cancer Driver | No | 23 | 0.084870848708487 | 35 | 6 | 0.022140221402214 | 0 |
IQGAP2-201 | IQGAP2 | Q13576 | Ras GTPase-activating-like protein IQGAP2 | chr5 | GO:0032956 | Not Cancer Driver | No | 159 | 0.1009523809523809 | 257 | 36 | 0.0228571428571428 | 0 |
ITGB3-201 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0032956 | Not Cancer Driver | No | 92 | 0.116751269035533 | 68 | 5 | 0.0063451776649746 | 28 |
LRP1-201 | LRP1 | Q07954 | Prolow-density lipoprotein receptor-related protein 1 | chr12 | GO:0032956 | Not Cancer Driver | No | 512 | 0.1126760563380281 | 319 | 38 | 0.008362676056338 | 1 |
MLST8-232 | MLST8 | Q9BVC4 | Target of rapamycin complex subunit LST8 | chr16 | GO:0032956 | Not Cancer Driver | No | 24 | 0.0736196319018405 | 45 | 3 | 0.00920245398773 | 0 |
MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0032956 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
NEDD9-202 | NEDD9 | Q14511 | Enhancer of filamentation 1 | chr6 | GO:0032956 | Not Cancer Driver | No | 80 | 0.0959232613908872 | 520 | 55 | 0.065947242206235 | 0 |
ODAM-206 | ODAM | A1E959 | Odontogenic ameloblast-associated protein | chr4 | GO:0032956 | Not Cancer Driver | No | 49 | 0.1756272401433691 | 140 | 17 | 0.060931899641577 | 0 |
OR2A4-201 | OR2A4 | O95047 | Olfactory receptor 2A4 | chr6 | GO:0032956 | Not Cancer Driver | No | 36 | 0.1161290322580645 | 0 | 0 | 0.0 | 0 |
PAK1-202 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0032956 | Not Cancer Driver | No | 36 | 0.0660550458715596 | 300 | 19 | 0.0348623853211009 | 2 |
PAK3-201 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0032956 | Not Cancer Driver | No | 95 | 0.1699463327370304 | 286 | 48 | 0.0858676207513416 | 2 |
PDGFA-201 | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0032956 | Not Cancer Driver | No | 26 | 0.1232227488151658 | 75 | 10 | 0.0473933649289099 | 0 |
PDGFRA-201 | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0032956 | Census, Compendium | Yes | 213 | 0.1955922865013774 | 173 | 36 | 0.0330578512396694 | 2 |
PDGFRB-201 | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0032956 | Census, Compendium | Yes | 134 | 0.1211573236889692 | 233 | 40 | 0.0361663652802893 | 7 |
PEAK3-201 | PEAK3 | Q6ZS72 | Protein PEAK3 | chr19 | GO:0032956 | Not Cancer Driver | No | 27 | 0.0570824524312896 | 174 | 13 | 0.0274841437632135 | 0 |
PRKCD-201 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0032956 | Compendium | Yes | 52 | 0.0769230769230769 | 43 | 7 | 0.0103550295857988 | 0 |
PTK2B-201 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0032956 | Not Cancer Driver | No | 117 | 0.1159563924677899 | 263 | 23 | 0.0227948463825569 | 0 |
RAC1-201 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0032956 | Census, Compendium | Yes | 61 | 0.3177083333333333 | 2 | 0 | 0.0 | 6 |
RAC3-201 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | GO:0032956 | Not Cancer Driver | No | 20 | 0.1041666666666666 | 0 | 0 | 0.0 | 4 |
RALA-201 | RALA | P11233 | Ras-related protein Ral-A | chr7 | GO:0032956 | Not Cancer Driver | No | 29 | 0.1407766990291262 | 34 | 3 | 0.0145631067961165 | 4 |
RAPGEF3-205 | RAPGEF3 | O95398 | Rap guanine nucleotide exchange factor 3 | chr12 | GO:0032956 | Not Cancer Driver | No | 79 | 0.085590465872156 | 197 | 18 | 0.0195016251354279 | 0 |
RHOA-202 | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0032956 | Census, Compendium | Yes | 92 | 0.4766839378238341 | 46 | 12 | 0.0621761658031088 | 2 |
RHOC-202 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | GO:0032956 | Not Cancer Driver | No | 23 | 0.1191709844559585 | 53 | 4 | 0.0207253886010362 | 0 |
RHOD-201 | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | GO:0032956 | Not Cancer Driver | No | 16 | 0.0761904761904762 | 10 | 0 | 0.0 | 0 |
RHOF-201 | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | GO:0032956 | Not Cancer Driver | No | 15 | 0.0710900473933649 | 11 | 0 | 0.0 | 0 |
RHOG-201 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | GO:0032956 | Not Cancer Driver | No | 20 | 0.1047120418848167 | 22 | 3 | 0.0157068062827225 | 0 |
RHOQ-201 | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | GO:0032956 | Not Cancer Driver | No | 19 | 0.0926829268292682 | 0 | 0 | 0.0 | 0 |
RICTOR-202 | RICTOR | Q6R327 | Rapamycin-insensitive companion of mTOR | chr5 | GO:0032956 | Not Cancer Driver | No | 144 | 0.0843091334894613 | 365 | 34 | 0.0199063231850117 | 0 |
RND1-201 | RND1 | Q92730 | Rho-related GTP-binding protein Rho6 | chr12 | GO:0032956 | Not Cancer Driver | No | 35 | 0.1508620689655172 | 9 | 1 | 0.0043103448275862 | 0 |
RND2-202 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | GO:0032956 | Not Cancer Driver | No | 17 | 0.0748898678414096 | 54 | 4 | 0.0176211453744493 | 0 |
RND3-201 | RND3 | P61587 | Rho-related GTP-binding protein RhoE | chr2 | GO:0032956 | Not Cancer Driver | No | 23 | 0.0942622950819672 | 70 | 7 | 0.0286885245901639 | 0 |
ROCK1-201 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0032956 | Not Cancer Driver | No | 116 | 0.0856720827178729 | 780 | 61 | 0.0450516986706056 | 0 |
ROCK2-202 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | GO:0032956 | Not Cancer Driver | No | 110 | 0.0792507204610951 | 734 | 61 | 0.0439481268011527 | 0 |
SH3BP1-210 | SH3BP1 | Q9Y3L3 | SH3 domain-binding protein 1 | chr22 | GO:0032956 | Not Cancer Driver | No | 50 | 0.0713266761768901 | 438 | 33 | 0.0470756062767475 | 0 |
SIGLEC15-201 | SIGLEC15 | Q6ZMC9 | Sialic acid-binding Ig-like lectin 15 | chr18 | GO:0032956 | Not Cancer Driver | No | 18 | 0.0548780487804878 | 101 | 11 | 0.0335365853658536 | 0 |
SLC4A2-202 | SLC4A2 | P04920 | Anion exchange protein 2 | chr7 | GO:0032956 | Not Cancer Driver | No | 113 | 0.0910556003223207 | 511 | 45 | 0.0362610797743755 | 0 |
SMIM22-209 | SMIM22 | K7EJ46 | Small integral membrane protein 22 | chr16 | GO:0032956 | Not Cancer Driver | No | 1 | 0.0120481927710843 | 20 | 1 | 0.0120481927710843 | 0 |
STAU2-229 | STAU2 | Q9NUL3 | Double-stranded RNA-binding protein Staufen homolog 2 | chr8 | GO:0032956 | Not Cancer Driver | No | 54 | 0.0947368421052631 | 486 | 45 | 0.0789473684210526 | 0 |
TAOK1-201 | TAOK1 | Q7L7X3 | Serine/threonine-protein kinase TAO1 | chr17 | GO:0032956 | Not Cancer Driver | No | 94 | 0.0939060939060939 | 602 | 48 | 0.0479520479520479 | 7 |
TAOK2-202 | TAOK2 | Q9UL54 | Serine/threonine-protein kinase TAO2 | chr16 | GO:0032956 | Not Cancer Driver | No | 129 | 0.1044534412955465 | 668 | 68 | 0.0550607287449392 | 0 |
TESK1-201 | TESK1 | Q15569 | Dual specificity testis-specific protein kinase 1 | chr9 | GO:0032956 | Not Cancer Driver | No | 51 | 0.0814696485623003 | 340 | 27 | 0.0431309904153354 | 0 |
TRPM2-203 | TRPM2 | O94759 | Transient receptor potential cation channel subfamily M member 2 | chr21 | GO:0032956 | Not Cancer Driver | No | 224 | 0.1490352628077179 | 267 | 37 | 0.0246174318030605 | 0 |
TWF2-201 | TWF2 | Q6IBS0 | Twinfilin-2 | chr3 | GO:0032956 | Not Cancer Driver | No | 28 | 0.0802292263610315 | 59 | 8 | 0.0229226361031518 | 0 |