Total number of protein in "GO:0033138" GO term: 74
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKAP9-201 | AKAP9 | Q99996 | A-kinase anchor protein 9 | chr7 | GO:0033138 | Census | Yes | 352 | 0.090094701817251 | 2287 | 200 | 0.0511901714870744 | 1 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0033138 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| ANGPT1-202 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0033138 | Not Cancer Driver | No | 100 | 0.2008032128514056 | 131 | 10 | 0.0200803212851405 | 1 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0033138 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
| ARAF-202 | ARAF | P10398 | Serine/threonine-protein kinase A-Raf | chrX | GO:0033138 | Census, Compendium | Yes | 61 | 0.1006600660066006 | 181 | 26 | 0.0429042904290429 | 0 |
| ATP2B4-203 | ATP2B4 | P23634 | Plasma membrane calcium-transporting ATPase 4 | chr1 | GO:0033138 | Not Cancer Driver | No | 113 | 0.0937759336099585 | 264 | 20 | 0.0165975103734439 | 0 |
| AVP-201 | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0033138 | Not Cancer Driver | No | 11 | 0.0670731707317073 | 26 | 1 | 0.0060975609756097 | 26 |
| AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0033138 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
| BAG4-201 | BAG4 | O95429 | BAG family molecular chaperone regulator 4 | chr8 | GO:0033138 | Not Cancer Driver | No | 40 | 0.087527352297593 | 402 | 36 | 0.0787746170678337 | 0 |
| BCAR3-201 | BCAR3 | O75815 | Breast cancer anti-estrogen resistance protein 3 | chr1 | GO:0033138 | Not Cancer Driver | No | 74 | 0.0896969696969696 | 397 | 34 | 0.0412121212121212 | 0 |
| BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0033138 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
| BDNF-202 | BDNF | P23560 | Brain-derived neurotrophic factor | chr11 | GO:0033138 | Not Cancer Driver | No | 33 | 0.1336032388663967 | 80 | 12 | 0.048582995951417 | 0 |
| BRAF-220 | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | GO:0033138 | Census, Compendium | Yes | 755 | 0.9856396866840732 | 311 | 30 | 0.0391644908616188 | 35 |
| CAV1-201 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0033138 | Not Cancer Driver | No | 23 | 0.1292134831460674 | 2 | 0 | 0.0 | 0 |
| CD44-208 | CD44 | P16070 | CD44 antigen | chr11 | GO:0033138 | Not Cancer Driver | No | 58 | 0.0781671159029649 | 547 | 50 | 0.0673854447439353 | 0 |
| CNOT9-201 | CNOT9 | Q92600 | CCR4-NOT transcription complex subunit 9 | chr2 | GO:0033138 | Compendium | Yes | 32 | 0.1070234113712374 | 30 | 0 | 0.0 | 0 |
| CREBL2-201 | CREBL2 | O60519 | cAMP-responsive element-binding protein-like 2 | chr12 | GO:0033138 | Not Cancer Driver | No | 11 | 0.0916666666666666 | 78 | 4 | 0.0333333333333333 | 0 |
| DOCK7-219 | DOCK7 | Q96N67 | Dedicator of cytokinesis protein 7 | chr1 | GO:0033138 | Not Cancer Driver | No | 183 | 0.0855140186915887 | 455 | 33 | 0.0154205607476635 | 0 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0033138 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
| EIF4G1-202 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | GO:0033138 | Not Cancer Driver | No | 157 | 0.0981863664790494 | 1080 | 103 | 0.0644152595372107 | 2 |
| FNIP1-203 | FNIP1 | Q8TF40 | Folliculin-interacting protein 1 | chr5 | GO:0033138 | Not Cancer Driver | No | 94 | 0.0806174957118353 | 386 | 30 | 0.0257289879931389 | 0 |
| FNIP2-201 | FNIP2 | Q9P278 | Folliculin-interacting protein 2 | chr4 | GO:0033138 | Not Cancer Driver | No | 87 | 0.078096947935368 | 556 | 53 | 0.0475763016157989 | 0 |
| GCG-202 | GCG | P01275 | Pro-glucagon | chr2 | GO:0033138 | Not Cancer Driver | No | 40 | 0.2222222222222222 | 83 | 20 | 0.1111111111111111 | 0 |
| GSK3A-201 | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0033138 | Not Cancer Driver | No | 33 | 0.0683229813664596 | 180 | 5 | 0.010351966873706 | 0 |
| HDAC6-201 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0033138 | Not Cancer Driver | No | 122 | 0.1004115226337448 | 409 | 35 | 0.0288065843621399 | 0 |
| IL11-201 | IL11 | P20809 | Interleukin-11 | chr19 | GO:0033138 | Not Cancer Driver | No | 10 | 0.050251256281407 | 70 | 4 | 0.0201005025125628 | 0 |
| IL6-201 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0033138 | Not Cancer Driver | No | 32 | 0.1509433962264151 | 58 | 6 | 0.0283018867924528 | 0 |
| IP6K2-201 | IP6K2 | Q9UHH9 | Inositol hexakisphosphate kinase 2 | chr3 | GO:0033138 | Not Cancer Driver | No | 29 | 0.068075117370892 | 96 | 6 | 0.0140845070422535 | 0 |
| IRGM-202 | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0033138 | Not Cancer Driver | No | 7 | 0.0386740331491712 | 51 | 0 | 0.0 | 0 |
| LATS1-207 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | GO:0033138 | Census, Compendium | Yes | 122 | 0.1079646017699115 | 790 | 74 | 0.0654867256637168 | 0 |
| LIF-201 | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0033138 | Not Cancer Driver | No | 18 | 0.0891089108910891 | 0 | 0 | 0.0 | 0 |
| MAD2L2-207 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0033138 | Not Cancer Driver | No | 16 | 0.0758293838862559 | 0 | 0 | 0.0 | 1 |
| MAPKAP1-201 | MAPKAP1 | Q9BPZ7 | Target of rapamycin complex 2 subunit MAPKAP1 | chr9 | GO:0033138 | Not Cancer Driver | No | 57 | 0.1091954022988505 | 173 | 17 | 0.0325670498084291 | 0 |
| MIF-201 | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:0033138 | Not Cancer Driver | No | 4 | 0.0347826086956521 | 0 | 0 | 0.0 | 0 |
| MTCP1-202 | MTCP1 | P56278 | Protein p13 MTCP-1 | chrX | GO:0033138 | Census, Compendium | Yes | 11 | 0.102803738317757 | 6 | 0 | 0.0 | 0 |
| NGF-201 | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0033138 | Not Cancer Driver | No | 56 | 0.2323651452282157 | 94 | 21 | 0.0871369294605809 | 1 |
| NOS1-201 | NOS1 | P29475 | Nitric oxide synthase 1 | chr12 | GO:0033138 | Not Cancer Driver | No | 329 | 0.2294281729428172 | 342 | 84 | 0.0585774058577405 | 0 |
| NTF3-201 | NTF3 | P20783 | Neurotrophin-3 | chr12 | GO:0033138 | Not Cancer Driver | No | 49 | 0.1906614785992217 | 102 | 23 | 0.0894941634241245 | 0 |
| NTF4-201 | NTF4 | P34130 | Neurotrophin-4 | chr19 | GO:0033138 | Not Cancer Driver | No | 18 | 0.0857142857142857 | 56 | 3 | 0.0142857142857142 | 0 |
| NTRK2-246 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0033138 | Not Cancer Driver | No | 103 | 0.1253041362530413 | 117 | 14 | 0.0170316301703163 | 1 |
| NTRK3-217 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0033138 | Census, Compendium | Yes | 214 | 0.2550655542312277 | 56 | 15 | 0.0178784266984505 | 3 |
| OPRD1-201 | OPRD1 | P41143 | Delta-type opioid receptor | chr1 | GO:0033138 | Not Cancer Driver | No | 53 | 0.1424731182795699 | 30 | 2 | 0.0053763440860215 | 0 |
| OSM-201 | OSM | P13725 | Oncostatin-M | chr22 | GO:0033138 | Not Cancer Driver | No | 36 | 0.1428571428571428 | 114 | 20 | 0.0793650793650793 | 0 |
| PAK1-202 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0033138 | Not Cancer Driver | No | 36 | 0.0660550458715596 | 300 | 19 | 0.0348623853211009 | 2 |
| PARK7-201 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0033138 | Not Cancer Driver | No | 8 | 0.0423280423280423 | 30 | 0 | 0.0 | 6 |
| PDCD10-201 | PDCD10 | Q9BUL8 | Programmed cell death protein 10 | chr3 | GO:0033138 | Not Cancer Driver | No | 25 | 0.1179245283018868 | 25 | 3 | 0.0141509433962264 | 0 |
| PFN2-201 | PFN2 | P35080 | Profilin-2 | chr3 | GO:0033138 | Not Cancer Driver | No | 11 | 0.0785714285714285 | 0 | 0 | 0.0 | 0 |
| PINK1-201 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0033138 | Not Cancer Driver | No | 46 | 0.0791738382099827 | 99 | 8 | 0.0137693631669535 | 24 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0033138 | Census | Yes | 164 | 0.1798245614035087 | 190 | 31 | 0.0339912280701754 | 2 |
| PTGS2-201 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0033138 | Not Cancer Driver | No | 68 | 0.1125827814569536 | 31 | 4 | 0.0066225165562913 | 0 |
| RAF1-201 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | GO:0033138 | Census, Compendium | Yes | 64 | 0.0987654320987654 | 169 | 30 | 0.0462962962962962 | 18 |
| RIPK2-201 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0033138 | Not Cancer Driver | No | 43 | 0.0796296296296296 | 143 | 14 | 0.0259259259259259 | 0 |
| RPTOR-201 | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0033138 | Not Cancer Driver | No | 149 | 0.1116104868913857 | 242 | 18 | 0.0134831460674157 | 0 |
| SFRP2-201 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0033138 | Not Cancer Driver | No | 37 | 0.1254237288135593 | 1 | 0 | 0.0 | 0 |
| SH2D3A-201 | SH2D3A | Q9BRG2 | SH2 domain-containing protein 3A | chr19 | GO:0033138 | Not Cancer Driver | No | 52 | 0.0902777777777777 | 308 | 30 | 0.0520833333333333 | 0 |
| SH2D3C-201 | SH2D3C | Q8N5H7 | SH2 domain-containing protein 3C | chr9 | GO:0033138 | Not Cancer Driver | No | 81 | 0.0941860465116279 | 443 | 52 | 0.0604651162790697 | 0 |
| SMYD3-214 | SMYD3 | Q9H7B4 | Histone-lysine N-methyltransferase SMYD3 | chr1 | GO:0033138 | Not Cancer Driver | No | 48 | 0.1121495327102803 | 2 | 0 | 0.0 | 0 |
| SNCA-205 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0033138 | Not Cancer Driver | No | 15 | 0.1071428571428571 | 107 | 10 | 0.0714285714285714 | 5 |
| SPRY2-202 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0033138 | Not Cancer Driver | No | 32 | 0.1015873015873015 | 170 | 19 | 0.0603174603174603 | 1 |
| STK4-202 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | GO:0033138 | Not Cancer Driver | No | 49 | 0.1006160164271047 | 233 | 20 | 0.0410677618069815 | 0 |
| STOX1-201 | STOX1 | Q6ZVD7 | Storkhead-box protein 1 | chr10 | GO:0033138 | Not Cancer Driver | No | 79 | 0.0798786653185035 | 660 | 54 | 0.0546006066734074 | 2 |
| TBK1-201 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0033138 | Not Cancer Driver | No | 68 | 0.093278463648834 | 42 | 4 | 0.0054869684499314 | 12 |
| TCL1A-201 | TCL1A | P56279 | T-cell leukemia/lymphoma protein 1A | chr14 | GO:0033138 | Census | Yes | 28 | 0.2456140350877192 | 5 | 1 | 0.0087719298245614 | 0 |
| TCL1B-201 | TCL1B | O95988 | T-cell leukemia/lymphoma protein 1B | chr14 | GO:0033138 | Not Cancer Driver | No | 31 | 0.2421875 | 11 | 1 | 0.0078125 | 0 |
| TENM1-201 | TENM1 | Q9UKZ4 | Teneurin-1 | chrX | GO:0033138 | Not Cancer Driver | No | 544 | 0.1996330275229357 | 484 | 127 | 0.0466055045871559 | 0 |
| TFRC-201 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | GO:0033138 | Census | Yes | 66 | 0.0868421052631579 | 80 | 4 | 0.0052631578947368 | 1 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0033138 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNKS1BP1-201 | TNKS1BP1 | Q9C0C2 | 182 kDa tankyrase-1-binding protein | chr11 | GO:0033138 | Not Cancer Driver | No | 167 | 0.0965876229034123 | 1726 | 166 | 0.0960092539039907 | 0 |
| TRIM6-201 | TRIM6 | Q9C030 | Tripartite motif-containing protein 6 | chr11 | GO:0033138 | Not Cancer Driver | No | 58 | 0.1188524590163934 | 48 | 12 | 0.0245901639344262 | 0 |
| TXN-202 | TXN | P10599 | Thioredoxin | chr9 | GO:0033138 | Not Cancer Driver | No | 5 | 0.0476190476190476 | 0 | 0 | 0.0 | 0 |
| UCN-201 | UCN | P55089 | Urocortin | chr2 | GO:0033138 | Not Cancer Driver | No | 7 | 0.0564516129032258 | 61 | 4 | 0.032258064516129 | 0 |
| VEGFA-226 | VEGFA | P15692 | Vascular endothelial growth factor A, long form | chr6 | GO:0033138 | Not Cancer Driver | No | 24 | 0.060759493670886 | 215 | 9 | 0.0227848101265822 | 0 |
| WNT3A-201 | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0033138 | Not Cancer Driver | No | 60 | 0.1704545454545454 | 37 | 2 | 0.0056818181818181 | 0 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0033138 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |