Total number of protein in "GO:0033674" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALK-201 | ALK | Q9UM73 | ALK tyrosine kinase receptor | chr2 | GO:0033674 | Census, Compendium | Yes | 233 | 0.1438271604938271 | 577 | 79 | 0.0487654320987654 | 12 |
| AXL-201 | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0033674 | Not Cancer Driver | No | 131 | 0.1465324384787472 | 342 | 51 | 0.0570469798657718 | 0 |
| CD4-201 | CD4 | P01730 | T-cell surface glycoprotein CD4 | chr12 | GO:0033674 | Not Cancer Driver | No | 50 | 0.1091703056768559 | 56 | 7 | 0.0152838427947598 | 0 |
| CD74-201 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0033674 | Census | Yes | 24 | 0.081081081081081 | 186 | 15 | 0.0506756756756756 | 0 |
| CSF1R-210 | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0033674 | Census | Yes | 101 | 0.1039094650205761 | 124 | 12 | 0.0123456790123456 | 20 |
| DDR1-225 | DDR1 | Q08345 | Epithelial discoidin domain-containing receptor 1 | chr6 | GO:0033674 | Not Cancer Driver | No | 98 | 0.1073384446878422 | 253 | 41 | 0.044906900328587 | 0 |
| DDR2-201 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | GO:0033674 | Census | Yes | 129 | 0.1508771929824561 | 120 | 25 | 0.0292397660818713 | 7 |
| DRD4-201 | DRD4 | P21917 | D(4) dopamine receptor | chr11 | GO:0033674 | Not Cancer Driver | No | 15 | 0.035799522673031 | 109 | 0 | 0.0 | 0 |
| DSTYK-202 | DSTYK | Q6XUX3 | Dual serine/threonine and tyrosine protein kinase | chr1 | GO:0033674 | Not Cancer Driver | No | 88 | 0.0947255113024757 | 113 | 6 | 0.0064585575888051 | 2 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0033674 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
| ENST00000640655 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0033674 | Not Cancer Driver | No | 92 | 0.0758450123660346 | 721 | 45 | 0.0370981038746908 | 0 |
| EPHA1-201 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | GO:0033674 | Not Cancer Driver | No | 109 | 0.1116803278688524 | 211 | 29 | 0.0297131147540983 | 0 |
| EPHA2-201 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0033674 | Compendium | Yes | 147 | 0.1506147540983606 | 188 | 33 | 0.033811475409836 | 3 |
| EPHB4-201 | EPHB4 | P54760 | Ephrin type-B receptor 4 | chr7 | GO:0033674 | Not Cancer Driver | No | 101 | 0.1023302938196555 | 186 | 18 | 0.0182370820668693 | 11 |
| ERBB2-201 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0033674 | Census, Compendium | Yes | 249 | 0.198406374501992 | 315 | 32 | 0.0254980079681274 | 1 |
| ERBB3-201 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0033674 | Census, Compendium | Yes | 265 | 0.1974664679582712 | 398 | 59 | 0.0439642324888226 | 3 |
| ERBB4-202 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0033674 | Census, Compendium | Yes | 376 | 0.2874617737003058 | 324 | 95 | 0.0726299694189602 | 2 |
| FGFR1-214 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0033674 | Census, Compendium | Yes | 92 | 0.1119221411192214 | 231 | 26 | 0.0316301703163017 | 69 |
| FGFR2-206 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0033674 | Census, Compendium | Yes | 193 | 0.2350791717417783 | 229 | 34 | 0.0414129110840438 | 57 |
| FGFR3-205 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | GO:0033674 | Census, Compendium | Yes | 134 | 0.1662531017369727 | 241 | 18 | 0.0223325062034739 | 32 |
| FGFR4-201 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | GO:0033674 | Census, Compendium | Yes | 101 | 0.1259351620947631 | 163 | 27 | 0.0336658354114713 | 0 |
| FLT1-201 | FLT1 | P17948 | Vascular endothelial growth factor receptor 1 | chr13 | GO:0033674 | Not Cancer Driver | No | 212 | 0.1584454409566517 | 103 | 17 | 0.0127055306427503 | 0 |
| FLT3-201 | FLT3 | P36888 | Receptor-type tyrosine-protein kinase FLT3 | chr13 | GO:0033674 | Census, Compendium | Yes | 153 | 0.1540785498489426 | 64 | 19 | 0.0191339375629405 | 0 |
| FLT4-201 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0033674 | Census, Compendium | Yes | 203 | 0.1489361702127659 | 259 | 33 | 0.0242112986060161 | 14 |
| HLA-DRB1-201 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | GO:0033674 | Not Cancer Driver | No | 11 | 0.0413533834586466 | 12 | 0 | 0.0 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0033674 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| INSR-201 | INSR | P06213 | Insulin receptor | chr19 | GO:0033674 | Not Cancer Driver | No | 139 | 0.1005788712011577 | 282 | 37 | 0.0267727930535455 | 63 |
| INSRR-201 | INSRR | P14616 | Insulin receptor-related protein | chr1 | GO:0033674 | Not Cancer Driver | No | 213 | 0.164225134926754 | 229 | 34 | 0.0262143407864302 | 0 |
| KDR-201 | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0033674 | Census, Compendium | Yes | 276 | 0.2035398230088495 | 276 | 40 | 0.0294985250737463 | 2 |
| LMO4-202 | LMO4 | P61968 | LIM domain transcription factor LMO4 | chr1 | GO:0033674 | Not Cancer Driver | No | 29 | 0.1757575757575757 | 11 | 1 | 0.006060606060606 | 0 |
| LTK-201 | LTK | P29376 | Leukocyte tyrosine kinase receptor | chr15 | GO:0033674 | Not Cancer Driver | No | 63 | 0.0729166666666666 | 301 | 17 | 0.0196759259259259 | 0 |
| MERTK-201 | MERTK | Q12866 | Tyrosine-protein kinase Mer | chr2 | GO:0033674 | Not Cancer Driver | No | 134 | 0.1341341341341341 | 161 | 25 | 0.025025025025025 | 3 |
| MET-202 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0033674 | Census, Compendium | Yes | 161 | 0.1158273381294964 | 62 | 10 | 0.0071942446043165 | 16 |
| MRE11-201 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0033674 | Not Cancer Driver | No | 61 | 0.0861581920903954 | 292 | 28 | 0.03954802259887 | 1 |
| MST1R-201 | MST1R | Q04912 | Macrophage-stimulating protein receptor | chr3 | GO:0033674 | Not Cancer Driver | No | 147 | 0.105 | 183 | 24 | 0.0171428571428571 | 1 |
| MUSK-204 | MUSK | O15146 | Muscle, skeletal receptor tyrosine-protein kinase | chr9 | GO:0033674 | Not Cancer Driver | No | 145 | 0.1668584579976985 | 35 | 7 | 0.0080552359033371 | 7 |
| NBN-201 | NBN | O60934 | Nibrin | chr8 | GO:0033674 | Census | Yes | 63 | 0.0835543766578249 | 420 | 45 | 0.059681697612732 | 1 |
| NTRK1-206 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0033674 | Census, Compendium | Yes | 133 | 0.1670854271356784 | 57 | 8 | 0.0100502512562814 | 23 |
| NTRK2-246 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0033674 | Not Cancer Driver | No | 103 | 0.1253041362530413 | 117 | 14 | 0.0170316301703163 | 1 |
| NTRK3-217 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0033674 | Census, Compendium | Yes | 214 | 0.2550655542312277 | 56 | 15 | 0.0178784266984505 | 3 |
| PDGFRA-201 | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0033674 | Census, Compendium | Yes | 213 | 0.1955922865013774 | 173 | 36 | 0.0330578512396694 | 2 |
| PDGFRB-201 | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0033674 | Census, Compendium | Yes | 134 | 0.1211573236889692 | 233 | 40 | 0.0361663652802893 | 7 |
| PIFO-202 | PIFO | Q8TCI5 | Protein pitchfork | chr1 | GO:0033674 | Not Cancer Driver | No | 19 | 0.0994764397905759 | 71 | 8 | 0.0418848167539267 | 0 |
| RAD50-201 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0033674 | Not Cancer Driver | No | 106 | 0.0807926829268292 | 730 | 50 | 0.0381097560975609 | 0 |
| RET-202 | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:0033674 | Census, Compendium | Yes | 176 | 0.1579892280071813 | 108 | 11 | 0.0098743267504488 | 91 |
| ROR1-201 | ROR1 | Q01973 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | chr1 | GO:0033674 | Not Cancer Driver | No | 113 | 0.1205976520811099 | 281 | 37 | 0.03948772678762 | 1 |
| ROR2-201 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0033674 | Not Cancer Driver | No | 164 | 0.1739130434782608 | 304 | 58 | 0.0615058324496288 | 5 |
| ROS1-202 | ROS1 | P08922 | Proto-oncogene tyrosine-protein kinase ROS | chr6 | GO:0033674 | Census | Yes | 356 | 0.1516829995739241 | 197 | 45 | 0.0191734128674904 | 0 |
| RYK-208 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:0033674 | Not Cancer Driver | No | 38 | 0.0626029654036243 | 85 | 3 | 0.0049423393739703 | 0 |
| TEK-201 | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0033674 | Not Cancer Driver | No | 145 | 0.1290035587188612 | 126 | 13 | 0.0115658362989323 | 9 |
| TIE1-201 | TIE1 | P35590 | Tyrosine-protein kinase receptor Tie-1 | chr1 | GO:0033674 | Not Cancer Driver | No | 156 | 0.1370826010544815 | 223 | 36 | 0.031634446397188 | 0 |
| TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0033674 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
| TYRO3-201 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0033674 | Not Cancer Driver | No | 86 | 0.096629213483146 | 197 | 18 | 0.0202247191011235 | 0 |
| ZNF16-202 | ZNF16 | P17020 | Zinc finger protein 16 | chr8 | GO:0033674 | Not Cancer Driver | No | 66 | 0.0967741935483871 | 295 | 24 | 0.0351906158357771 | 0 |
| ZNF622-201 | ZNF622 | Q969S3 | Cytoplasmic 60S subunit biogenesis factor ZNF622 | chr5 | GO:0033674 | Not Cancer Driver | No | 52 | 0.1090146750524109 | 220 | 25 | 0.0524109014675052 | 0 |