Total number of protein in "GO:0034599" GO term: 94
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC1-202 | ABCC1 | P33527 | Multidrug resistance-associated protein 1 | chr16 | GO:0034599 | Not Cancer Driver | No | 157 | 0.1025473546701502 | 123 | 18 | 0.0117570215545395 | 1 |
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0034599 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| AIF1-203 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:0034599 | Not Cancer Driver | No | 12 | 0.0816326530612244 | 61 | 5 | 0.0340136054421768 | 0 |
| ALDH3B1-201 | ALDH3B1 | P43353 | Aldehyde dehydrogenase family 3 member B1 | chr11 | GO:0034599 | Not Cancer Driver | No | 28 | 0.0598290598290598 | 23 | 5 | 0.0106837606837606 | 0 |
| ARL6IP5-201 | ARL6IP5 | O75915 | PRA1 family protein 3 | chr3 | GO:0034599 | Not Cancer Driver | No | 14 | 0.0744680851063829 | 0 | 0 | 0.0 | 0 |
| ARNT-202 | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | GO:0034599 | Census | Yes | 61 | 0.0773130544993662 | 511 | 47 | 0.0595690747782002 | 0 |
| ATF2-201 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0034599 | Not Cancer Driver | No | 42 | 0.0831683168316831 | 451 | 36 | 0.0712871287128712 | 0 |
| ATF4-206 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0034599 | Not Cancer Driver | No | 46 | 0.131054131054131 | 261 | 33 | 0.094017094017094 | 0 |
| ATP13A2-201 | ATP13A2 | Q9NQ11 | Polyamine-transporting ATPase 13A2 | chr1 | GO:0034599 | Not Cancer Driver | No | 125 | 0.1059322033898305 | 121 | 9 | 0.0076271186440677 | 9 |
| ATP2A2-204 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | GO:0034599 | Not Cancer Driver | No | 106 | 0.1017274472168906 | 78 | 13 | 0.0124760076775431 | 40 |
| BRF2-201 | BRF2 | Q9HAW0 | Transcription factor IIIB 50 kDa subunit | chr8 | GO:0034599 | Not Cancer Driver | No | 26 | 0.0620525059665871 | 138 | 7 | 0.0167064439140811 | 0 |
| CCS-208 | CCS | O14618 | Copper chaperone for superoxide dismutase | chr11 | GO:0034599 | Not Cancer Driver | No | 22 | 0.0802919708029197 | 105 | 8 | 0.0291970802919708 | 0 |
| CHCHD2-201 | CHCHD2 | Q9Y6H1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | chr7 | GO:0034599 | Not Cancer Driver | No | 10 | 0.0662251655629139 | 114 | 7 | 0.0463576158940397 | 1 |
| CHCHD4-202 | CHCHD4 | Q8N4Q1 | Mitochondrial intermembrane space import and assembly protein 40 | chr3 | GO:0034599 | Not Cancer Driver | No | 11 | 0.0774647887323943 | 83 | 3 | 0.0211267605633802 | 0 |
| DHRS2-201 | DHRS2 | Q13268 | Dehydrogenase/reductase SDR family member 2, mitochondrial | chr14 | GO:0034599 | Not Cancer Driver | No | 32 | 0.1142857142857142 | 0 | 0 | 0.0 | 0 |
| EDNRA-209 | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0034599 | Not Cancer Driver | No | 52 | 0.1217798594847775 | 21 | 5 | 0.0117096018735363 | 2 |
| EIF2S1-201 | EIF2S1 | P05198 | Eukaryotic translation initiation factor 2 subunit 1 | chr14 | GO:0034599 | Not Cancer Driver | No | 25 | 0.0793650793650793 | 59 | 3 | 0.0095238095238095 | 0 |
| ERMP1-202 | ERMP1 | Q7Z2K6 | Endoplasmic reticulum metallopeptidase 1 | chr9 | GO:0034599 | Not Cancer Driver | No | 54 | 0.0597345132743362 | 95 | 4 | 0.0044247787610619 | 0 |
| ETV5-201 | ETV5 | P41161 | ETS translocation variant 5 | chr3 | GO:0034599 | Census, Compendium | Yes | 58 | 0.1137254901960784 | 301 | 30 | 0.0588235294117647 | 0 |
| FANCC-201 | FANCC | Q00597 | Fanconi anemia group C protein | chr9 | GO:0034599 | Census, Compendium | Yes | 38 | 0.068100358422939 | 13 | 0 | 0.0 | 3 |
| FANCD2-212 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | GO:0034599 | Census, Compendium | Yes | 116 | 0.0799448656099241 | 182 | 9 | 0.0062026188835286 | 3 |
| FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0034599 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
| FOXO3-202 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0034599 | Census, Compendium | Yes | 54 | 0.0802377414561664 | 597 | 50 | 0.0742942050520059 | 0 |
| G6PD-202 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | GO:0034599 | Not Cancer Driver | No | 64 | 0.1242718446601941 | 28 | 3 | 0.0058252427184466 | 51 |
| GJB2-202 | GJB2 | P29033 | Gap junction beta-2 protein | chr13 | GO:0034599 | Not Cancer Driver | No | 25 | 0.1106194690265486 | 0 | 0 | 0.0 | 41 |
| GPX1-202 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0034599 | Not Cancer Driver | No | 22 | 0.1083743842364532 | 12 | 3 | 0.0147783251231527 | 0 |
| GPX5-201 | GPX5 | O75715 | Epididymal secretory glutathione peroxidase | chr6 | GO:0034599 | Not Cancer Driver | No | 52 | 0.2352941176470588 | 9 | 2 | 0.0090497737556561 | 0 |
| GPX7-201 | GPX7 | Q96SL4 | Glutathione peroxidase 7 | chr1 | GO:0034599 | Not Cancer Driver | No | 20 | 0.106951871657754 | 6 | 1 | 0.0053475935828877 | 0 |
| GPX8-203 | GPX8 | Q8TED1 | Probable glutathione peroxidase 8 | chr5 | GO:0034599 | Not Cancer Driver | No | 12 | 0.0574162679425837 | 4 | 1 | 0.0047846889952153 | 0 |
| GSR-201 | GSR | P00390 | Glutathione reductase, mitochondrial | chr8 | GO:0034599 | Not Cancer Driver | No | 37 | 0.0708812260536398 | 55 | 4 | 0.0076628352490421 | 1 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0034599 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HM13-201 | HM13 | Q8TCT9 | Minor histocompatibility antigen H13 | chr20 | GO:0034599 | Not Cancer Driver | No | 30 | 0.0795755968169761 | 61 | 3 | 0.0079575596816976 | 0 |
| HSPA1A-201 | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0034599 | Not Cancer Driver | No | 20 | 0.0312012480499219 | 200 | 10 | 0.0156006240249609 | 0 |
| HSPA1B-201 | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0034599 | Not Cancer Driver | No | 19 | 0.0296411856474258 | 200 | 7 | 0.0109204368174727 | 0 |
| HTRA2-201 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0034599 | Compendium | Yes | 33 | 0.0720524017467248 | 127 | 7 | 0.0152838427947598 | 2 |
| KAT2B-201 | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0034599 | Not Cancer Driver | No | 78 | 0.09375 | 268 | 20 | 0.0240384615384615 | 0 |
| KEAP1-201 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0034599 | Census, Compendium | Yes | 217 | 0.3477564102564102 | 57 | 7 | 0.0112179487179487 | 0 |
| LONP1-201 | LONP1 | P36776 | Lon protease homolog, mitochondrial | chr19 | GO:0034599 | Not Cancer Driver | No | 75 | 0.0782064650677789 | 178 | 16 | 0.0166840458811261 | 10 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0034599 | Not Cancer Driver | No | 402 | 0.1590819153146023 | 91 | 13 | 0.0051444400474871 | 20 |
| MAPK8-206 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0034599 | Not Cancer Driver | No | 52 | 0.1217798594847775 | 94 | 9 | 0.0210772833723653 | 0 |
| MGAT3-201 | MGAT3 | Q09327 | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | chr22 | GO:0034599 | Not Cancer Driver | No | 86 | 0.1613508442776735 | 130 | 21 | 0.0393996247654784 | 0 |
| MSRA-201 | MSRA | Q9UJ68 | Mitochondrial peptide methionine sulfoxide reductase | chr8 | GO:0034599 | Not Cancer Driver | No | 42 | 0.1787234042553191 | 81 | 15 | 0.0638297872340425 | 0 |
| MT3-201 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0034599 | Not Cancer Driver | No | 4 | 0.0588235294117647 | 0 | 0 | 0.0 | 0 |
| NAGLU-201 | NAGLU | P54802 | Alpha-N-acetylglucosaminidase | chr17 | GO:0034599 | Not Cancer Driver | No | 57 | 0.0767160161507402 | 18 | 0 | 0.0 | 61 |
| NFE2L2-201 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0034599 | Census, Compendium | Yes | 235 | 0.3884297520661157 | 402 | 59 | 0.0975206611570247 | 4 |
| NME2-205 | NME2 | P22392 | Nucleoside diphosphate kinase B | chr17 | GO:0034599 | Not Cancer Driver | No | 9 | 0.0592105263157894 | 11 | 0 | 0.0 | 0 |
| NQO1-201 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | GO:0034599 | Not Cancer Driver | No | 11 | 0.0401459854014598 | 10 | 0 | 0.0 | 0 |
| NR4A2-201 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0034599 | Not Cancer Driver | No | 84 | 0.1404682274247491 | 262 | 32 | 0.0535117056856187 | 3 |
| NUDT2-203 | NUDT2 | P50583 | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] | chr9 | GO:0034599 | Not Cancer Driver | No | 14 | 0.0952380952380952 | 24 | 1 | 0.0068027210884353 | 0 |
| PARK7-201 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0034599 | Not Cancer Driver | No | 8 | 0.0423280423280423 | 30 | 0 | 0.0 | 6 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0034599 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PENK-202 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0034599 | Not Cancer Driver | No | 92 | 0.3445692883895131 | 143 | 55 | 0.2059925093632958 | 0 |
| PINK1-201 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0034599 | Not Cancer Driver | No | 46 | 0.0791738382099827 | 99 | 8 | 0.0137693631669535 | 24 |
| PNPT1-205 | PNPT1 | Q8TCS8 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial | chr2 | GO:0034599 | Not Cancer Driver | No | 67 | 0.0855683269476372 | 115 | 5 | 0.0063856960408684 | 2 |
| PPARGC1A-201 | PPARGC1A | Q9UBK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | chr4 | GO:0034599 | Not Cancer Driver | No | 91 | 0.1140350877192982 | 613 | 85 | 0.106516290726817 | 0 |
| PPIA-204 | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0034599 | Not Cancer Driver | No | 9 | 0.0545454545454545 | 24 | 1 | 0.006060606060606 | 0 |
| PRDX2-201 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | GO:0034599 | Not Cancer Driver | No | 22 | 0.1111111111111111 | 30 | 3 | 0.0151515151515151 | 0 |
| PRDX3-201 | PRDX3 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | chr10 | GO:0034599 | Not Cancer Driver | No | 17 | 0.06640625 | 23 | 2 | 0.0078125 | 2 |
| PRDX5-201 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | GO:0034599 | Not Cancer Driver | No | 13 | 0.0607476635514018 | 0 | 0 | 0.0 | 0 |
| PRKAA1-204 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0034599 | Not Cancer Driver | No | 54 | 0.0966010733452593 | 124 | 13 | 0.0232558139534883 | 0 |
| PRKAA2-201 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0034599 | Not Cancer Driver | No | 90 | 0.1630434782608695 | 98 | 18 | 0.0326086956521739 | 0 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0034599 | Census | Yes | 164 | 0.1798245614035087 | 190 | 31 | 0.0339912280701754 | 2 |
| PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0034599 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
| PRKRA-201 | PRKRA | O75569 | Interferon-inducible double-stranded RNA-dependent protein kinase activator A | chr2 | GO:0034599 | Not Cancer Driver | No | 28 | 0.0894568690095846 | 104 | 8 | 0.0255591054313099 | 1 |
| PRR5L-216 | PRR5L | Q6MZQ0 | Proline-rich protein 5-like | chr11 | GO:0034599 | Not Cancer Driver | No | 45 | 0.1222826086956521 | 108 | 11 | 0.029891304347826 | 0 |
| PYCR1-201 | PYCR1 | P32322 | Pyrroline-5-carboxylate reductase 1, mitochondrial | chr17 | GO:0034599 | Not Cancer Driver | No | 18 | 0.0564263322884012 | 66 | 6 | 0.018808777429467 | 7 |
| PYCR2-201 | PYCR2 | Q96C36 | Pyrroline-5-carboxylate reductase 2 | chr1 | GO:0034599 | Not Cancer Driver | No | 27 | 0.084375 | 41 | 1 | 0.003125 | 2 |
| PYROXD1-201 | PYROXD1 | Q8WU10 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 | chr12 | GO:0034599 | Not Cancer Driver | No | 45 | 0.09 | 34 | 2 | 0.004 | 2 |
| RAD52-202 | RAD52 | P43351 | DNA repair protein RAD52 homolog | chr12 | GO:0034599 | Not Cancer Driver | No | 30 | 0.0717703349282296 | 252 | 24 | 0.0574162679425837 | 0 |
| RBM11-201 | RBM11 | P57052 | Splicing regulator RBM11 | chr21 | GO:0034599 | Not Cancer Driver | No | 47 | 0.1672597864768683 | 125 | 23 | 0.0818505338078291 | 0 |
| RWDD1-202 | RWDD1 | Q9H446 | RWD domain-containing protein 1 | chr6 | GO:0034599 | Not Cancer Driver | No | 12 | 0.0493827160493827 | 169 | 7 | 0.0288065843621399 | 0 |
| SELENON-202 | SELENON | Q9NZV5 | Selenoprotein N | chr1 | GO:0034599 | Not Cancer Driver | No | 33 | 0.0559322033898305 | 94 | 2 | 0.0033898305084745 | 11 |
| SELENOS-203 | SELENOS | Q9BQE4 | Selenoprotein S | chr15 | GO:0034599 | Not Cancer Driver | No | 4 | 0.0211640211640211 | 123 | 3 | 0.0158730158730158 | 0 |
| SESN2-201 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0034599 | Not Cancer Driver | No | 54 | 0.1125 | 147 | 20 | 0.0416666666666666 | 0 |
| SETX-201 | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0034599 | Not Cancer Driver | No | 213 | 0.0795666791184161 | 1248 | 89 | 0.0332461710870377 | 19 |
| SIRT2-201 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0034599 | Not Cancer Driver | No | 40 | 0.1028277634961439 | 85 | 13 | 0.0334190231362467 | 0 |
| SLC1A1-201 | SLC1A1 | P43005 | Excitatory amino acid transporter 3 | chr9 | GO:0034599 | Not Cancer Driver | No | 50 | 0.0954198473282442 | 17 | 3 | 0.0057251908396946 | 1 |
| SLC25A24-203 | SLC25A24 | Q6NUK1 | Mitochondrial adenyl nucleotide antiporter SLC25A24 | chr1 | GO:0034599 | Not Cancer Driver | No | 28 | 0.0587002096436058 | 21 | 1 | 0.0020964360587002 | 1 |
| SLC4A11-207 | SLC4A11 | Q8NBS3 | Solute carrier family 4 member 11 | chr20 | GO:0034599 | Not Cancer Driver | No | 121 | 0.1382857142857143 | 69 | 5 | 0.0057142857142857 | 40 |
| SLC7A11-201 | SLC7A11 | Q9UPY5 | Cystine/glutamate transporter | chr4 | GO:0034599 | Not Cancer Driver | No | 55 | 0.1097804391217564 | 15 | 1 | 0.0019960079840319 | 0 |
| SNCA-205 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0034599 | Not Cancer Driver | No | 15 | 0.1071428571428571 | 107 | 10 | 0.0714285714285714 | 5 |
| SOD2-210 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0034599 | Not Cancer Driver | No | 21 | 0.0945945945945946 | 25 | 3 | 0.0135135135135135 | 0 |
| SRXN1-201 | SRXN1 | Q9BYN0 | Sulfiredoxin-1 | chr20 | GO:0034599 | Not Cancer Driver | No | 10 | 0.072992700729927 | 48 | 1 | 0.0072992700729927 | 0 |
| STAU1-207 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | GO:0034599 | Not Cancer Driver | No | 54 | 0.0935875216637781 | 458 | 45 | 0.0779896013864818 | 0 |
| STAU2-229 | STAU2 | Q9NUL3 | Double-stranded RNA-binding protein Staufen homolog 2 | chr8 | GO:0034599 | Not Cancer Driver | No | 54 | 0.0947368421052631 | 486 | 45 | 0.0789473684210526 | 0 |
| STX2-203 | STX2 | P32856 | Syntaxin-2 | chr12 | GO:0034599 | Not Cancer Driver | No | 32 | 0.1111111111111111 | 142 | 19 | 0.0659722222222222 | 0 |
| STX4-201 | STX4 | Q12846 | Syntaxin-4 | chr16 | GO:0034599 | Not Cancer Driver | No | 39 | 0.1313131313131313 | 153 | 16 | 0.0538720538720538 | 0 |
| SUMO4-201 | SUMO4 | Q6EEV6 | Small ubiquitin-related modifier 4 | chr6 | GO:0034599 | Not Cancer Driver | No | 6 | 0.0631578947368421 | 69 | 4 | 0.0421052631578947 | 0 |
| TBC1D24-210 | TBC1D24 | Q9ULP9 | TBC1 domain family member 24 | chr16 | GO:0034599 | Not Cancer Driver | No | 50 | 0.0894454382826475 | 33 | 1 | 0.0017889087656529 | 16 |
| TMEM161A-201 | TMEM161A | Q9NX61 | Transmembrane protein 161A | chr19 | GO:0034599 | Not Cancer Driver | No | 41 | 0.0855949895615866 | 22 | 6 | 0.0125260960334029 | 0 |
| VKORC1L1-201 | VKORC1L1 | Q8N0U8 | Vitamin K epoxide reductase complex subunit 1-like protein 1 | chr7 | GO:0034599 | Not Cancer Driver | No | 16 | 0.0909090909090909 | 0 | 0 | 0.0 | 0 |
| VRK2-201 | VRK2 | Q86Y07 | Serine/threonine-protein kinase VRK2 | chr2 | GO:0034599 | Not Cancer Driver | No | 44 | 0.0866141732283464 | 126 | 9 | 0.0177165354330708 | 0 |
| ZC3H12A-201 | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0034599 | Not Cancer Driver | No | 77 | 0.1285475792988314 | 397 | 38 | 0.0634390651085141 | 0 |
| ZFAND1-201 | ZFAND1 | Q8TCF1 | AN1-type zinc finger protein 1 | chr8 | GO:0034599 | Not Cancer Driver | No | 23 | 0.085820895522388 | 30 | 2 | 0.0074626865671641 | 0 |