Total number of protein in "GO:0034644" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AQP1-201 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0034644 | Not Cancer Driver | No | 30 | 0.1115241635687732 | 4 | 0 | 0.0 | 0 |
| ATF4-206 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0034644 | Not Cancer Driver | No | 46 | 0.131054131054131 | 261 | 33 | 0.094017094017094 | 0 |
| ATR-201 | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:0034644 | Census, Compendium | Yes | 261 | 0.098714069591528 | 107 | 11 | 0.0041603630862329 | 1 |
| AURKB-214 | AURKB | Q96GD4 | Aurora kinase B | chr17 | GO:0034644 | Not Cancer Driver | No | 31 | 0.0901162790697674 | 63 | 4 | 0.0116279069767441 | 0 |
| BAK1-201 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0034644 | Not Cancer Driver | No | 25 | 0.1184834123222748 | 58 | 5 | 0.0236966824644549 | 0 |
| BAX-202 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0034644 | Census | Yes | 24 | 0.125 | 39 | 2 | 0.0104166666666666 | 0 |
| BMF-201 | BMF | Q96LC9 | Bcl-2-modifying factor | chr15 | GO:0034644 | Not Cancer Driver | No | 16 | 0.0869565217391304 | 94 | 7 | 0.0380434782608695 | 0 |
| CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0034644 | Census | Yes | 26 | 0.0625 | 71 | 7 | 0.016826923076923 | 0 |
| CDC25A-201 | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | GO:0034644 | Not Cancer Driver | No | 45 | 0.0858778625954198 | 314 | 27 | 0.0515267175572519 | 0 |
| COPS9-205 | COPS9 | Q8WXC6 | COP9 signalosome complex subunit 9 | chr2 | GO:0034644 | Not Cancer Driver | No | 5 | 0.087719298245614 | 25 | 2 | 0.0350877192982456 | 0 |
| CREBBP-201 | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0034644 | Census, Compendium | Yes | 217 | 0.0888615888615888 | 1801 | 91 | 0.0372645372645372 | 30 |
| CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0034644 | Not Cancer Driver | No | 54 | 0.0711462450592885 | 102 | 2 | 0.0026350461133069 | 0 |
| CUL4B-231 | CUL4B | Q13620 | Cullin-4B | chrX | GO:0034644 | Not Cancer Driver | No | 83 | 0.0909090909090909 | 207 | 23 | 0.0251916757940854 | 2 |
| DDB1-201 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0034644 | Not Cancer Driver | No | 98 | 0.0859649122807017 | 50 | 8 | 0.0070175438596491 | 3 |
| DDB2-201 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | GO:0034644 | Census, Compendium | Yes | 35 | 0.081967213114754 | 71 | 5 | 0.0117096018735363 | 2 |
| DHX36-213 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0034644 | Not Cancer Driver | No | 110 | 0.1091269841269841 | 223 | 27 | 0.0267857142857142 | 0 |
| EIF2AK4-201 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0034644 | Not Cancer Driver | No | 113 | 0.0685263796240145 | 496 | 34 | 0.0206185567010309 | 2 |
| EIF2S1-201 | EIF2S1 | P05198 | Eukaryotic translation initiation factor 2 subunit 1 | chr14 | GO:0034644 | Not Cancer Driver | No | 25 | 0.0793650793650793 | 59 | 3 | 0.0095238095238095 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0034644 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| ERCC4-201 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0034644 | Census | Yes | 81 | 0.0884279475982532 | 226 | 19 | 0.0207423580786026 | 15 |
| INO80-209 | INO80 | Q9ULG1 | Chromatin-remodeling ATPase INO80 | chr15 | GO:0034644 | Compendium | Yes | 137 | 0.0880462724935732 | 682 | 67 | 0.0430591259640102 | 0 |
| KDM1A-201 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0034644 | Not Cancer Driver | No | 48 | 0.056338028169014 | 291 | 21 | 0.0246478873239436 | 3 |
| MAPK13-201 | MAPK13 | O15264 | Mitogen-activated protein kinase 13 | chr6 | GO:0034644 | Not Cancer Driver | No | 34 | 0.0931506849315068 | 50 | 11 | 0.0301369863013698 | 0 |
| METTL3-201 | METTL3 | Q86U44 | N6-adenosine-methyltransferase catalytic subunit | chr14 | GO:0034644 | Not Cancer Driver | No | 60 | 0.1034482758620689 | 274 | 24 | 0.0413793103448275 | 0 |
| MYC-206 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0034644 | Census, Compendium | Yes | 72 | 0.158590308370044 | 325 | 41 | 0.0903083700440528 | 0 |
| N4BP1-201 | N4BP1 | O75113 | NEDD4-binding protein 1 | chr16 | GO:0034644 | Not Cancer Driver | No | 71 | 0.0792410714285714 | 433 | 38 | 0.0424107142857142 | 0 |
| NEDD4-208 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0034644 | Not Cancer Driver | No | 99 | 0.0750568612585291 | 717 | 55 | 0.0416982562547384 | 0 |
| NFATC4-201 | NFATC4 | Q14934 | Nuclear factor of activated T-cells, cytoplasmic 4 | chr14 | GO:0034644 | Not Cancer Driver | No | 122 | 0.1352549889135255 | 685 | 92 | 0.1019955654101995 | 0 |
| NOC2L-201 | NOC2L | Q9Y3T9 | Nucleolar complex protein 2 homolog | chr1 | GO:0034644 | Not Cancer Driver | No | 54 | 0.0720961281708945 | 281 | 22 | 0.0293724966622162 | 0 |
| NPM1-201 | NPM1 | P06748 | Nucleophosmin | chr5 | GO:0034644 | Census, Compendium | Yes | 25 | 0.0850340136054421 | 249 | 19 | 0.064625850340136 | 0 |
| NSMCE3-201 | NSMCE3 | Q96MG7 | Non-structural maintenance of chromosomes element 3 homolog | chr15 | GO:0034644 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 129 | 6 | 0.0197368421052631 | 2 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0034644 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PBK-201 | PBK | Q96KB5 | Lymphokine-activated killer T-cell-originated protein kinase | chr8 | GO:0034644 | Not Cancer Driver | No | 16 | 0.0496894409937888 | 92 | 6 | 0.0186335403726708 | 0 |
| PCNA-201 | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0034644 | Not Cancer Driver | No | 19 | 0.0727969348659003 | 22 | 2 | 0.0076628352490421 | 1 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0034644 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| POLD1-201 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0034644 | Census, Compendium | Yes | 118 | 0.1065943992773261 | 210 | 17 | 0.015356820234869 | 2 |
| POLK-201 | POLK | Q9UBT6 | DNA polymerase kappa | chr5 | GO:0034644 | Not Cancer Driver | No | 66 | 0.0758620689655172 | 294 | 25 | 0.028735632183908 | 0 |
| PRKCD-201 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0034644 | Compendium | Yes | 52 | 0.0769230769230769 | 43 | 7 | 0.0103550295857988 | 0 |
| PTPRK-206 | PTPRK | Q15262 | Receptor-type tyrosine-protein phosphatase kappa | chr6 | GO:0034644 | Census, Compendium | Yes | 233 | 0.1619179986101459 | 302 | 44 | 0.0305767894371091 | 0 |
| RBX1-201 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0034644 | Not Cancer Driver | No | 9 | 0.0833333333333333 | 18 | 1 | 0.0092592592592592 | 0 |
| RHBDD1-202 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | GO:0034644 | Not Cancer Driver | No | 29 | 0.092063492063492 | 69 | 8 | 0.0253968253968253 | 0 |
| RHNO1-204 | RHNO1 | Q9BSD3 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 | chr12 | GO:0034644 | Not Cancer Driver | No | 22 | 0.0924369747899159 | 193 | 18 | 0.0756302521008403 | 0 |
| RPL26-213 | RPL26 | P61254 | Large ribosomal subunit protein uL24 | chr17 | GO:0034644 | Not Cancer Driver | No | 16 | 0.1103448275862069 | 114 | 13 | 0.0896551724137931 | 0 |
| RUVBL2-206 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0034644 | Not Cancer Driver | No | 52 | 0.1123110151187904 | 100 | 11 | 0.0237580993520518 | 0 |
| SDE2-201 | SDE2 | Q6IQ49 | Splicing regulator SDE2 | chr1 | GO:0034644 | Not Cancer Driver | No | 40 | 0.0886917960088691 | 290 | 23 | 0.0509977827050997 | 0 |
| SMPD1-201 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0034644 | Not Cancer Driver | No | 51 | 0.080824088748019 | 51 | 4 | 0.0063391442155309 | 105 |
| TAF1-204 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0034644 | Not Cancer Driver | No | 278 | 0.1484249866524292 | 1174 | 156 | 0.0832888414308595 | 5 |
| TMEM161A-201 | TMEM161A | Q9NX61 | Transmembrane protein 161A | chr19 | GO:0034644 | Not Cancer Driver | No | 41 | 0.0855949895615866 | 22 | 6 | 0.0125260960334029 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0034644 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TP53INP1-201 | TP53INP1 | Q96A56 | Tumor protein p53-inducible nuclear protein 1 | chr8 | GO:0034644 | Not Cancer Driver | No | 21 | 0.0875 | 134 | 12 | 0.05 | 0 |
| TRIAP1-202 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0034644 | Not Cancer Driver | No | 8 | 0.1052631578947368 | 20 | 1 | 0.0131578947368421 | 0 |
| USP28-201 | USP28 | Q96RU2 | Ubiquitin carboxyl-terminal hydrolase 28 | chr11 | GO:0034644 | Not Cancer Driver | No | 106 | 0.0984215413184772 | 311 | 18 | 0.0167130919220055 | 0 |
| USP47-203 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0034644 | Not Cancer Driver | No | 86 | 0.0625454545454545 | 426 | 24 | 0.0174545454545454 | 0 |
| YY1-201 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | GO:0034644 | Not Cancer Driver | No | 29 | 0.0700483091787439 | 337 | 21 | 0.0507246376811594 | 2 |
| ZBTB1-207 | ZBTB1 | Q9Y2K1 | Zinc finger and BTB domain-containing protein 1 | chr14 | GO:0034644 | Not Cancer Driver | No | 50 | 0.0701262272089761 | 273 | 17 | 0.0238429172510518 | 0 |