Total number of protein in "GO:0034976" GO term: 94
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0034976 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| AFF4-201 | AFF4 | Q9UHB7 | AF4/FMR2 family member 4 | chr5 | GO:0034976 | Census | Yes | 106 | 0.0911435941530524 | 994 | 97 | 0.0834049871023215 | 2 |
| AGR2-203 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | GO:0034976 | Not Cancer Driver | No | 14 | 0.08 | 20 | 1 | 0.0057142857142857 | 1 |
| ALOX15-201 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0034976 | Not Cancer Driver | No | 64 | 0.0966767371601208 | 46 | 4 | 0.0060422960725075 | 0 |
| ANKS4B-201 | ANKS4B | Q8N8V4 | Ankyrin repeat and SAM domain-containing protein 4B | chr16 | GO:0034976 | Not Cancer Driver | No | 58 | 0.1390887290167865 | 239 | 30 | 0.0719424460431654 | 0 |
| ATF3-202 | ATF3 | P18847 | Cyclic AMP-dependent transcription factor ATF-3 | chr1 | GO:0034976 | Not Cancer Driver | No | 19 | 0.1049723756906077 | 118 | 13 | 0.0718232044198895 | 0 |
| ATF4-206 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0034976 | Not Cancer Driver | No | 46 | 0.131054131054131 | 261 | 33 | 0.094017094017094 | 0 |
| ATF6-201 | ATF6 | P18850 | Cyclic AMP-dependent transcription factor ATF-6 alpha | chr1 | GO:0034976 | Not Cancer Driver | No | 62 | 0.0925373134328358 | 474 | 43 | 0.0641791044776119 | 2 |
| ATF6B-210 | ATF6B | Q99941 | Cyclic AMP-dependent transcription factor ATF-6 beta | chr6 | GO:0034976 | Not Cancer Driver | No | 58 | 0.0825035561877667 | 557 | 46 | 0.0654338549075391 | 0 |
| ATP2A1-201 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | GO:0034976 | Not Cancer Driver | No | 125 | 0.1248751248751248 | 80 | 9 | 0.0089910089910089 | 1 |
| ATP2A2-204 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | GO:0034976 | Not Cancer Driver | No | 106 | 0.1017274472168906 | 78 | 13 | 0.0124760076775431 | 40 |
| BCAP31-201 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | GO:0034976 | Not Cancer Driver | No | 27 | 0.1097560975609756 | 104 | 13 | 0.0528455284552845 | 0 |
| BCL2L11-204 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0034976 | Not Cancer Driver | No | 37 | 0.1868686868686868 | 131 | 16 | 0.0808080808080808 | 0 |
| CDK5RAP3-201 | CDK5RAP3 | Q96JB5 | CDK5 regulatory subunit-associated protein 3 | chr17 | GO:0034976 | Not Cancer Driver | No | 37 | 0.0731225296442687 | 99 | 18 | 0.0355731225296442 | 0 |
| CEBPB-201 | CEBPB | P17676 | CCAAT/enhancer-binding protein beta | chr20 | GO:0034976 | Not Cancer Driver | No | 2 | 0.0057971014492753 | 276 | 0 | 0.0 | 0 |
| CERT1-215 | CERT1 | Q9Y5P4 | Ceramide transfer protein | chr5 | GO:0034976 | Not Cancer Driver | No | 51 | 0.0817307692307692 | 215 | 17 | 0.0272435897435897 | 2 |
| CFTR-201 | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | GO:0034976 | Not Cancer Driver | No | 216 | 0.1459459459459459 | 145 | 9 | 0.006081081081081 | 130 |
| CREB3L1-206 | CREB3L1 | Q96BA8 | Cyclic AMP-responsive element-binding protein 3-like protein 1 | chr11 | GO:0034976 | Census | Yes | 54 | 0.1040462427745664 | 373 | 39 | 0.0751445086705202 | 0 |
| CREB3L2-201 | CREB3L2 | Q70SY1 | Cyclic AMP-responsive element-binding protein 3-like protein 2 | chr7 | GO:0034976 | Census | Yes | 49 | 0.0942307692307692 | 365 | 38 | 0.073076923076923 | 0 |
| CREB3L3-201 | CREB3L3 | Q68CJ9 | Cyclic AMP-responsive element-binding protein 3-like protein 3 | chr19 | GO:0034976 | Not Cancer Driver | No | 81 | 0.175704989154013 | 340 | 56 | 0.1214750542299349 | 1 |
| CXCL8-201 | CXCL8 | P10145 | Interleukin-8 | chr4 | GO:0034976 | Not Cancer Driver | No | 12 | 0.1212121212121212 | 0 | 0 | 0.0 | 0 |
| DDIT3-201 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0034976 | Census | Yes | 19 | 0.1124260355029585 | 161 | 17 | 0.1005917159763313 | 0 |
| DDRGK1-201 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | GO:0034976 | Not Cancer Driver | No | 26 | 0.0828025477707006 | 181 | 19 | 0.0605095541401273 | 0 |
| DNAJB9-201 | DNAJB9 | Q9UBS3 | DnaJ homolog subfamily B member 9 | chr7 | GO:0034976 | Not Cancer Driver | No | 21 | 0.0941704035874439 | 109 | 12 | 0.0538116591928251 | 0 |
| DNAJC10-201 | DNAJC10 | Q8IXB1 | DnaJ homolog subfamily C member 10 | chr2 | GO:0034976 | Not Cancer Driver | No | 77 | 0.0970996216897856 | 37 | 3 | 0.0037831021437578 | 0 |
| EIF2AK3-201 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0034976 | Not Cancer Driver | No | 102 | 0.0913978494623656 | 411 | 37 | 0.0331541218637992 | 1 |
| EIF2B5-226 | EIF2B5 | Q13144 | Translation initiation factor eIF-2B subunit epsilon | chr3 | GO:0034976 | Not Cancer Driver | No | 49 | 0.0679611650485436 | 179 | 9 | 0.0124826629680998 | 21 |
| EIF2S1-201 | EIF2S1 | P05198 | Eukaryotic translation initiation factor 2 subunit 1 | chr14 | GO:0034976 | Not Cancer Driver | No | 25 | 0.0793650793650793 | 59 | 3 | 0.0095238095238095 | 0 |
| ELAVL4-203 | ELAVL4 | P26378 | ELAV-like protein 4 | chr1 | GO:0034976 | Not Cancer Driver | No | 85 | 0.2207792207792207 | 117 | 21 | 0.0545454545454545 | 0 |
| ENST00000593731 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0034976 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| ERN1-201 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0034976 | Not Cancer Driver | No | 91 | 0.0931422722620266 | 251 | 17 | 0.0174002047082906 | 0 |
| ERN2-201 | ERN2 | Q76MJ5 | Serine/threonine-protein kinase/endoribonuclease IRE2 | chr16 | GO:0034976 | Not Cancer Driver | No | 151 | 0.1630669546436285 | 214 | 34 | 0.0367170626349892 | 0 |
| ERO1A-201 | ERO1A | Q96HE7 | ERO1-like protein alpha | chr14 | GO:0034976 | Not Cancer Driver | No | 34 | 0.0726495726495726 | 33 | 4 | 0.0085470085470085 | 0 |
| ERP27-201 | ERP27 | Q96DN0 | Endoplasmic reticulum resident protein 27 | chr12 | GO:0034976 | Not Cancer Driver | No | 25 | 0.0915750915750915 | 28 | 7 | 0.0256410256410256 | 0 |
| ERP44-201 | ERP44 | Q9BS26 | Endoplasmic reticulum resident protein 44 | chr9 | GO:0034976 | Not Cancer Driver | No | 33 | 0.0812807881773399 | 43 | 3 | 0.0073891625615763 | 0 |
| FICD-204 | FICD | Q9BVA6 | Protein adenylyltransferase FICD | chr12 | GO:0034976 | Not Cancer Driver | No | 35 | 0.0764192139737991 | 42 | 3 | 0.0065502183406113 | 0 |
| FLOT1-201 | FLOT1 | O75955 | Flotillin-1 | chr6 | GO:0034976 | Not Cancer Driver | No | 31 | 0.072599531615925 | 122 | 10 | 0.0234192037470726 | 0 |
| GORASP2-201 | GORASP2 | Q9H8Y8 | Golgi reassembly-stacking protein 2 | chr2 | GO:0034976 | Not Cancer Driver | No | 42 | 0.0929203539823008 | 288 | 24 | 0.0530973451327433 | 0 |
| HERPUD1-204 | HERPUD1 | Q15011 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein | chr16 | GO:0034976 | Census | Yes | 28 | 0.0716112531969309 | 249 | 11 | 0.0281329923273657 | 0 |
| HSP90B1-201 | HSP90B1 | P14625 | Endoplasmin | chr12 | GO:0034976 | Not Cancer Driver | No | 56 | 0.0697384806973848 | 269 | 17 | 0.0211706102117061 | 0 |
| HSPA5-201 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | GO:0034976 | Not Cancer Driver | No | 49 | 0.0749235474006116 | 282 | 26 | 0.0397553516819571 | 0 |
| HYOU1-218 | HYOU1 | Q9Y4L1 | Hypoxia up-regulated protein 1 | chr11 | GO:0034976 | Not Cancer Driver | No | 98 | 0.0980980980980981 | 373 | 36 | 0.036036036036036 | 0 |
| JUN-201 | JUN | P05412 | Transcription factor Jun | chr1 | GO:0034976 | Census | Yes | 26 | 0.0785498489425981 | 283 | 17 | 0.0513595166163142 | 0 |
| KCNJ8-201 | KCNJ8 | Q15842 | ATP-sensitive inward rectifier potassium channel 8 | chr12 | GO:0034976 | Not Cancer Driver | No | 78 | 0.1839622641509433 | 69 | 17 | 0.0400943396226415 | 1 |
| MAP3K5-201 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0034976 | Not Cancer Driver | No | 146 | 0.106259097525473 | 244 | 23 | 0.0167394468704512 | 0 |
| MARCKS-201 | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | GO:0034976 | Not Cancer Driver | No | 5 | 0.0150602409638554 | 328 | 5 | 0.0150602409638554 | 0 |
| MBTPS1-201 | MBTPS1 | Q14703 | Membrane-bound transcription factor site-1 protease | chr16 | GO:0034976 | Not Cancer Driver | No | 120 | 0.1140684410646387 | 209 | 31 | 0.029467680608365 | 1 |
| MBTPS2-202 | MBTPS2 | O43462 | Membrane-bound transcription factor site-2 protease | chrX | GO:0034976 | Not Cancer Driver | No | 41 | 0.0789980732177264 | 16 | 3 | 0.0057803468208092 | 9 |
| NCK1-207 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0034976 | Not Cancer Driver | No | 41 | 0.1087533156498673 | 111 | 15 | 0.039787798408488 | 0 |
| NHLRC1-201 | NHLRC1 | Q6VVB1 | E3 ubiquitin-protein ligase NHLRC1 | chr6 | GO:0034976 | Not Cancer Driver | No | 52 | 0.1316455696202531 | 18 | 3 | 0.0075949367088607 | 22 |
| NIBAN1-201 | NIBAN1 | Q9BZQ8 | Protein Niban 1 | chr1 | GO:0034976 | Not Cancer Driver | No | 114 | 0.1228448275862068 | 400 | 63 | 0.0678879310344827 | 0 |
| NOD1-201 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0034976 | Not Cancer Driver | No | 98 | 0.1028331584470094 | 39 | 4 | 0.0041972717733473 | 0 |
| NOD2-201 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0034976 | Not Cancer Driver | No | 130 | 0.125 | 41 | 3 | 0.0028846153846153 | 15 |
| NRBF2-201 | NRBF2 | Q96F24 | Nuclear receptor-binding factor 2 | chr10 | GO:0034976 | Not Cancer Driver | No | 21 | 0.073170731707317 | 225 | 15 | 0.0522648083623693 | 0 |
| OS9-202 | OS9 | Q13438 | Protein OS-9 | chr12 | GO:0034976 | Not Cancer Driver | No | 62 | 0.0929535232383808 | 451 | 43 | 0.0644677661169415 | 0 |
| P4HB-201 | P4HB | P07237 | Protein disulfide-isomerase | chr17 | GO:0034976 | Not Cancer Driver | No | 41 | 0.0807086614173228 | 80 | 13 | 0.0255905511811023 | 1 |
| PDIA2-201 | PDIA2 | Q13087 | Protein disulfide-isomerase A2 | chr16 | GO:0034976 | Not Cancer Driver | No | 47 | 0.0895238095238095 | 83 | 6 | 0.0114285714285714 | 0 |
| PDIA3-201 | PDIA3 | P30101 | Protein disulfide-isomerase A3 | chr15 | GO:0034976 | Not Cancer Driver | No | 34 | 0.0673267326732673 | 98 | 6 | 0.0118811881188118 | 0 |
| PDIA4-204 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | GO:0034976 | Not Cancer Driver | No | 61 | 0.0945736434108527 | 147 | 18 | 0.027906976744186 | 0 |
| PDIA6-201 | PDIA6 | Q15084 | Protein disulfide-isomerase A6 | chr2 | GO:0034976 | Not Cancer Driver | No | 41 | 0.0931818181818181 | 82 | 8 | 0.0181818181818181 | 0 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0034976 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PIK3R2-201 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0034976 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| PPP1R15A-201 | PPP1R15A | O75807 | Protein phosphatase 1 regulatory subunit 15A | chr19 | GO:0034976 | Not Cancer Driver | No | 64 | 0.0949554896142433 | 635 | 55 | 0.0816023738872403 | 0 |
| PPP1R15B-201 | PPP1R15B | Q5SWA1 | Protein phosphatase 1 regulatory subunit 15B | chr1 | GO:0034976 | Not Cancer Driver | No | 58 | 0.0813464235624123 | 413 | 35 | 0.0490883590462833 | 1 |
| PPP2CB-201 | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | GO:0034976 | Not Cancer Driver | No | 27 | 0.087378640776699 | 12 | 0 | 0.0 | 0 |
| PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0034976 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
| QRICH1-202 | QRICH1 | Q2TAL8 | Transcriptional regulator QRICH1 | chr3 | GO:0034976 | Not Cancer Driver | No | 75 | 0.0966494845360824 | 423 | 45 | 0.0579896907216494 | 0 |
| RASGRF1-202 | RASGRF1 | Q13972 | Ras-specific guanine nucleotide-releasing factor 1 | chr15 | GO:0034976 | Not Cancer Driver | No | 169 | 0.1327572663000785 | 333 | 53 | 0.0416339355852317 | 0 |
| RASGRF2-201 | RASGRF2 | O14827 | Ras-specific guanine nucleotide-releasing factor 2 | chr5 | GO:0034976 | Not Cancer Driver | No | 158 | 0.1277283751010509 | 276 | 42 | 0.0339531123686337 | 0 |
| RNF183-207 | RNF183 | Q96D59 | E3 ubiquitin-protein ligase RNF183 | chr9 | GO:0034976 | Not Cancer Driver | No | 19 | 0.0989583333333333 | 29 | 1 | 0.0052083333333333 | 0 |
| SCAMP5-202 | SCAMP5 | Q8TAC9 | Secretory carrier-associated membrane protein 5 | chr15 | GO:0034976 | Not Cancer Driver | No | 31 | 0.1319148936170212 | 2 | 1 | 0.0042553191489361 | 0 |
| SEC16A-210 | SEC16A | O15027 | Protein transport protein Sec16A | chr9 | GO:0034976 | Not Cancer Driver | No | 196 | 0.0831565549427238 | 1931 | 161 | 0.0683071701315231 | 0 |
| SGF29-201 | SGF29 | Q96ES7 | SAGA-associated factor 29 | chr16 | GO:0034976 | Not Cancer Driver | No | 25 | 0.0853242320819112 | 132 | 12 | 0.0409556313993174 | 0 |
| SRPX-201 | SRPX | P78539 | Sushi repeat-containing protein SRPX | chrX | GO:0034976 | Not Cancer Driver | No | 54 | 0.1163793103448275 | 60 | 9 | 0.0193965517241379 | 0 |
| TARDBP-201 | TARDBP | Q13148 | TAR DNA-binding protein 43 | chr1 | GO:0034976 | Not Cancer Driver | No | 36 | 0.0869565217391304 | 202 | 12 | 0.0289855072463768 | 21 |
| THBS1-201 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0034976 | Not Cancer Driver | No | 153 | 0.1307692307692307 | 321 | 50 | 0.0427350427350427 | 0 |
| THBS4-201 | THBS4 | P35443 | Thrombospondin-4 | chr5 | GO:0034976 | Not Cancer Driver | No | 99 | 0.1030176899063475 | 282 | 33 | 0.0343392299687825 | 0 |
| TMEM258-204 | TMEM258 | P61165 | Transmembrane protein 258 | chr11 | GO:0034976 | Not Cancer Driver | No | 9 | 0.1139240506329113 | 0 | 0 | 0.0 | 0 |
| TMEM259-202 | TMEM259 | Q4ZIN3 | Membralin | chr19 | GO:0034976 | Not Cancer Driver | No | 30 | 0.0483870967741935 | 193 | 5 | 0.0080645161290322 | 0 |
| TMEM33-202 | TMEM33 | P57088 | Transmembrane protein 33 | chr4 | GO:0034976 | Not Cancer Driver | No | 14 | 0.0566801619433198 | 7 | 0 | 0.0 | 0 |
| TMTC3-201 | TMTC3 | Q6ZXV5 | Protein O-mannosyl-transferase TMTC3 | chr12 | GO:0034976 | Not Cancer Driver | No | 90 | 0.0984682713347921 | 82 | 4 | 0.0043763676148796 | 2 |
| TMX1-201 | TMX1 | Q9H3N1 | Thioredoxin-related transmembrane protein 1 | chr14 | GO:0034976 | Not Cancer Driver | No | 18 | 0.0642857142857142 | 62 | 6 | 0.0214285714285714 | 0 |
| TNFRSF10B-201 | TNFRSF10B | O14763 | Tumor necrosis factor receptor superfamily member 10B | chr8 | GO:0034976 | Not Cancer Driver | No | 36 | 0.0818181818181818 | 192 | 15 | 0.034090909090909 | 0 |
| TRAF2-201 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0034976 | Not Cancer Driver | No | 51 | 0.1017964071856287 | 4 | 1 | 0.0019960079840319 | 0 |
| TRIB3-201 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0034976 | Not Cancer Driver | No | 45 | 0.1256983240223463 | 113 | 17 | 0.047486033519553 | 0 |
| TTC23L-203 | TTC23L | Q6PF05 | Tetratricopeptide repeat protein 23-like | chr5 | GO:0034976 | Not Cancer Driver | No | 28 | 0.077562326869806 | 71 | 5 | 0.0138504155124653 | 0 |
| UBA5-202 | UBA5 | Q9GZZ9 | Ubiquitin-like modifier-activating enzyme 5 | chr3 | GO:0034976 | Not Cancer Driver | No | 26 | 0.0643564356435643 | 127 | 6 | 0.0148514851485148 | 7 |
| UBQLN1-202 | UBQLN1 | Q9UMX0 | Ubiquilin-1 | chr9 | GO:0034976 | Not Cancer Driver | No | 40 | 0.0679117147707979 | 545 | 38 | 0.064516129032258 | 0 |
| UFC1-201 | UFC1 | Q9Y3C8 | Ubiquitin-fold modifier-conjugating enzyme 1 | chr1 | GO:0034976 | Not Cancer Driver | No | 19 | 0.1137724550898203 | 10 | 0 | 0.0 | 2 |
| UFL1-201 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0034976 | Not Cancer Driver | No | 77 | 0.096977329974811 | 141 | 19 | 0.0239294710327455 | 0 |
| UFM1-201 | UFM1 | P61960 | Ubiquitin-fold modifier 1 | chr13 | GO:0034976 | Not Cancer Driver | No | 7 | 0.0823529411764705 | 0 | 0 | 0.0 | 1 |
| USP19-202 | USP19 | O94966 | Ubiquitin carboxyl-terminal hydrolase 19 | chr3 | GO:0034976 | Not Cancer Driver | No | 124 | 0.094081942336874 | 540 | 54 | 0.0409711684370258 | 0 |
| WFS1-201 | WFS1 | O76024 | Wolframin | chr4 | GO:0034976 | Not Cancer Driver | No | 78 | 0.0876404494382022 | 205 | 11 | 0.0123595505617977 | 40 |
| XBP1-201 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0034976 | Not Cancer Driver | No | 11 | 0.0421455938697318 | 171 | 6 | 0.0229885057471264 | 0 |