Total number of protein in "GO:0035264" GO term: 87
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADARB1-202 | ADARB1 | P78563 | Double-stranded RNA-specific editase 1 | chr21 | GO:0035264 | Not Cancer Driver | No | 71 | 0.0958164642375168 | 348 | 26 | 0.0350877192982456 | 1 |
| APBA1-201 | APBA1 | Q02410 | Amyloid-beta A4 precursor protein-binding family A member 1 | chr9 | GO:0035264 | Not Cancer Driver | No | 117 | 0.1397849462365591 | 558 | 78 | 0.0931899641577061 | 0 |
| APBA2-213 | APBA2 | Q99767 | Amyloid-beta A4 precursor protein-binding family A member 2 | chr15 | GO:0035264 | Not Cancer Driver | No | 151 | 0.2016021361815754 | 429 | 98 | 0.1308411214953271 | 0 |
| AR-201 | AR | P10275 | Androgen receptor | chrX | GO:0035264 | Census, Compendium | Yes | 116 | 0.1260869565217391 | 443 | 38 | 0.0413043478260869 | 144 |
| ARID5B-201 | ARID5B | Q14865 | AT-rich interactive domain-containing protein 5B | chr10 | GO:0035264 | Not Cancer Driver | No | 133 | 0.1119528619528619 | 770 | 82 | 0.069023569023569 | 0 |
| ATF5-201 | ATF5 | Q9Y2D1 | Cyclic AMP-dependent transcription factor ATF-5 | chr19 | GO:0035264 | Not Cancer Driver | No | 31 | 0.1099290780141844 | 242 | 27 | 0.0957446808510638 | 0 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0035264 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| ATN1-202 | ATN1 | P54259 | Atrophin-1 | chr12 | GO:0035264 | Not Cancer Driver | No | 111 | 0.0932773109243697 | 1176 | 109 | 0.0915966386554621 | 5 |
| ATRX-201 | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0035264 | Census, Compendium | Yes | 306 | 0.1227929373996789 | 1673 | 173 | 0.069422150882825 | 29 |
| CCM2-201 | CCM2 | Q9BSQ5 | Cerebral cavernous malformations 2 protein | chr7 | GO:0035264 | Not Cancer Driver | No | 47 | 0.1058558558558558 | 132 | 6 | 0.0135135135135135 | 3 |
| CDKN1C-203 | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | GO:0035264 | Not Cancer Driver | No | 3 | 0.0094936708860759 | 256 | 1 | 0.0031645569620253 | 6 |
| CELA1-201 | CELA1 | Q9UNI1 | Chymotrypsin-like elastase family member 1 | chr12 | GO:0035264 | Not Cancer Driver | No | 30 | 0.1162790697674418 | 21 | 0 | 0.0 | 0 |
| CLIC4-201 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | GO:0035264 | Not Cancer Driver | No | 23 | 0.0909090909090909 | 49 | 4 | 0.0158102766798418 | 0 |
| COL3A1-201 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0035264 | Census | Yes | 49 | 0.0334242837653478 | 1183 | 6 | 0.0040927694406548 | 86 |
| COMP-201 | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0035264 | Not Cancer Driver | No | 75 | 0.0990752972258916 | 307 | 39 | 0.0515191545574636 | 51 |
| COMT-202 | COMT | P21964 | Catechol O-methyltransferase | chr22 | GO:0035264 | Not Cancer Driver | No | 16 | 0.059040590405904 | 5 | 0 | 0.0 | 0 |
| CTC1-214 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:0035264 | Not Cancer Driver | No | 107 | 0.0879211175020542 | 106 | 4 | 0.0032867707477403 | 9 |
| EN1-201 | EN1 | Q05925 | Homeobox protein engrailed-1 | chr2 | GO:0035264 | Not Cancer Driver | No | 29 | 0.0739795918367346 | 358 | 20 | 0.0510204081632653 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0035264 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| ERCC1-202 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0035264 | Not Cancer Driver | No | 36 | 0.1212121212121212 | 107 | 14 | 0.0471380471380471 | 1 |
| ERCC2-204 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0035264 | Census, Compendium | Yes | 103 | 0.1355263157894737 | 5 | 0 | 0.0 | 30 |
| ERCC6-201 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0035264 | Not Cancer Driver | No | 142 | 0.0951105157401205 | 837 | 82 | 0.0549229738780977 | 9 |
| ETNK2-203 | ETNK2 | Q9NVF9 | Ethanolamine kinase 2 | chr1 | GO:0035264 | Not Cancer Driver | No | 21 | 0.0544041450777202 | 38 | 0 | 0.0 | 0 |
| EXT1-201 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0035264 | Census | Yes | 75 | 0.1005361930294906 | 60 | 7 | 0.0093833780160857 | 8 |
| FKBP8-206 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | GO:0035264 | Not Cancer Driver | No | 50 | 0.1213592233009708 | 161 | 19 | 0.0461165048543689 | 0 |
| FLVCR1-201 | FLVCR1 | Q9Y5Y0 | Heme transporter FLVCR1 | chr1 | GO:0035264 | Not Cancer Driver | No | 38 | 0.0684684684684684 | 117 | 5 | 0.009009009009009 | 5 |
| FOSL2-201 | FOSL2 | P15408 | Fos-related antigen 2 | chr2 | GO:0035264 | Not Cancer Driver | No | 39 | 0.1196319018404908 | 323 | 39 | 0.1196319018404908 | 0 |
| G6PC1-201 | G6PC1 | P35575 | Glucose-6-phosphatase catalytic subunit 1 | chr17 | GO:0035264 | Not Cancer Driver | No | 38 | 0.1064425770308123 | 0 | 0 | 0.0 | 44 |
| GHRH-202 | GHRH | P01286 | Somatoliberin | chr20 | GO:0035264 | Not Cancer Driver | No | 9 | 0.0833333333333333 | 36 | 4 | 0.037037037037037 | 0 |
| GIGYF2-201 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:0035264 | Not Cancer Driver | No | 73 | 0.0561970746728252 | 1098 | 62 | 0.0477290223248652 | 6 |
| GRHL2-206 | GRHL2 | Q6ISB3 | Grainyhead-like protein 2 homolog | chr8 | GO:0035264 | Not Cancer Driver | No | 73 | 0.1168 | 260 | 33 | 0.0528 | 2 |
| HEG1-201 | HEG1 | Q9ULI3 | Protein HEG homolog 1 | chr3 | GO:0035264 | Not Cancer Driver | No | 119 | 0.0861694424330195 | 985 | 97 | 0.0702389572773352 | 0 |
| HELT-204 | HELT | A6NFD8 | Hairy and enhancer of split-related protein HELT | chr4 | GO:0035264 | Not Cancer Driver | No | 22 | 0.0909090909090909 | 132 | 13 | 0.0537190082644628 | 0 |
| HESX1-201 | HESX1 | Q9UBX0 | Homeobox expressed in ES cells 1 | chr3 | GO:0035264 | Not Cancer Driver | No | 24 | 0.1297297297297297 | 59 | 7 | 0.0378378378378378 | 6 |
| HOXA5-201 | HOXA5 | P20719 | Homeobox protein Hox-A5 | chr7 | GO:0035264 | Not Cancer Driver | No | 40 | 0.1481481481481481 | 209 | 33 | 0.1222222222222222 | 0 |
| IHH-201 | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0035264 | Not Cancer Driver | No | 50 | 0.121654501216545 | 111 | 14 | 0.0340632603406326 | 5 |
| KAT2A-201 | KAT2A | Q92830 | Histone acetyltransferase KAT2A | chr17 | GO:0035264 | Not Cancer Driver | No | 70 | 0.08363201911589 | 251 | 11 | 0.013142174432497 | 0 |
| KLF2-201 | KLF2 | Q9Y5W3 | Krueppel-like factor 2 | chr19 | GO:0035264 | Not Cancer Driver | No | 10 | 0.028169014084507 | 283 | 2 | 0.0056338028169014 | 0 |
| LARGE1-202 | LARGE1 | O95461 | Xylosyl- and glucuronyltransferase LARGE1 | chr22 | GO:0035264 | Not Cancer Driver | No | 109 | 0.1441798941798941 | 92 | 16 | 0.0211640211640211 | 4 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0035264 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
| NOTCH2-201 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0035264 | Census, Compendium | Yes | 191 | 0.0772966410360178 | 631 | 61 | 0.0246863617968433 | 1 |
| NPR2-201 | NPR2 | P20594 | Atrial natriuretic peptide receptor 2 | chr9 | GO:0035264 | Not Cancer Driver | No | 106 | 0.1012416427889207 | 91 | 9 | 0.0085959885386819 | 20 |
| ODAD3-201 | ODAD3 | A5D8V7 | Outer dynein arm-docking complex subunit 3 | chr19 | GO:0035264 | Not Cancer Driver | No | 52 | 0.0873949579831932 | 362 | 31 | 0.0521008403361344 | 0 |
| PALB2-201 | PALB2 | Q86YC2 | Partner and localizer of BRCA2 | chr16 | GO:0035264 | Census | Yes | 95 | 0.0801011804384485 | 772 | 56 | 0.0472175379426644 | 1 |
| PKDCC-201 | PKDCC | Q504Y2 | Extracellular tyrosine-protein kinase PKDCC | chr2 | GO:0035264 | Not Cancer Driver | No | 27 | 0.0547667342799188 | 125 | 0 | 0.0 | 0 |
| PLAG1-201 | PLAG1 | Q6DJT9 | Zinc finger protein PLAG1 | chr8 | GO:0035264 | Census, Compendium | Yes | 77 | 0.154 | 209 | 34 | 0.068 | 0 |
| PLEC-201 | PLEC | Q15149 | Plectin | chr8 | GO:0035264 | Not Cancer Driver | No | 336 | 0.0717335610589239 | 2138 | 125 | 0.0266865926558497 | 2 |
| PLEKHA1-203 | PLEKHA1 | Q9HB21 | Pleckstrin homology domain-containing family A member 1 | chr10 | GO:0035264 | Not Cancer Driver | No | 48 | 0.1188118811881188 | 192 | 28 | 0.0693069306930693 | 0 |
| PPP1R13L-201 | PPP1R13L | Q8WUF5 | RelA-associated inhibitor | chr19 | GO:0035264 | Not Cancer Driver | No | 93 | 0.1123188405797101 | 659 | 75 | 0.0905797101449275 | 0 |
| PRICKLE1-201 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:0035264 | Not Cancer Driver | No | 118 | 0.1419975932611311 | 485 | 71 | 0.0854392298435619 | 3 |
| PTPN11-201 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0035264 | Census, Compendium | Yes | 92 | 0.1551433389544688 | 260 | 27 | 0.0455311973018549 | 44 |
| RARA-201 | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0035264 | Census, Compendium | Yes | 60 | 0.1298701298701298 | 167 | 14 | 0.0303030303030303 | 0 |
| RARB-214 | RARB | P10826 | Retinoic acid receptor beta | chr3 | GO:0035264 | Not Cancer Driver | No | 60 | 0.1318681318681318 | 148 | 17 | 0.0373626373626373 | 3 |
| RARG-203 | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0035264 | Not Cancer Driver | No | 69 | 0.1519823788546255 | 164 | 24 | 0.052863436123348 | 0 |
| RASAL2-203 | RASAL2 | Q9UJF2 | Ras GTPase-activating protein nGAP | chr1 | GO:0035264 | Not Cancer Driver | No | 134 | 0.1176470588235294 | 607 | 69 | 0.0605794556628621 | 0 |
| RBBP6-201 | RBBP6 | Q7Z6E9 | E3 ubiquitin-protein ligase RBBP6 | chr16 | GO:0035264 | Not Cancer Driver | No | 87 | 0.0485491071428571 | 1627 | 85 | 0.0474330357142857 | 0 |
| RC3H2-202 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | GO:0035264 | Not Cancer Driver | No | 99 | 0.0831234256926952 | 704 | 62 | 0.0520570948782535 | 0 |
| RMI1-202 | RMI1 | Q9H9A7 | RecQ-mediated genome instability protein 1 | chr9 | GO:0035264 | Not Cancer Driver | No | 38 | 0.0608 | 243 | 16 | 0.0256 | 0 |
| SCNN1B-202 | SCNN1B | P51168 | Amiloride-sensitive sodium channel subunit beta | chr16 | GO:0035264 | Not Cancer Driver | No | 64 | 0.1 | 62 | 4 | 0.00625 | 12 |
| SELENOM-201 | SELENOM | Q8WWX9 | Selenoprotein M | chr22 | GO:0035264 | Not Cancer Driver | No | 8 | 0.0551724137931034 | 21 | 2 | 0.0137931034482758 | 0 |
| SLC12A5-205 | SLC12A5 | Q9H2X9 | Solute carrier family 12 member 5 | chr20 | GO:0035264 | Not Cancer Driver | No | 203 | 0.1782265144863915 | 291 | 41 | 0.0359964881474978 | 5 |
| SLC1A2-201 | SLC1A2 | P43004 | Excitatory amino acid transporter 2 | chr11 | GO:0035264 | Not Cancer Driver | No | 56 | 0.0975609756097561 | 82 | 2 | 0.0034843205574912 | 3 |
| SLC25A25-201 | SLC25A25 | Q6KCM7 | Mitochondrial adenyl nucleotide antiporter SLC25A25 | chr9 | GO:0035264 | Not Cancer Driver | No | 25 | 0.0533049040511727 | 5 | 1 | 0.0021321961620469 | 0 |
| SLC4A10-206 | SLC4A10 | Q6U841 | Sodium-driven chloride bicarbonate exchanger | chr2 | GO:0035264 | Not Cancer Driver | No | 172 | 0.1538461538461538 | 340 | 58 | 0.0518783542039356 | 0 |
| SLITRK1-202 | SLITRK1 | Q96PX8 | SLIT and NTRK-like protein 1 | chr13 | GO:0035264 | Not Cancer Driver | No | 242 | 0.3477011494252873 | 126 | 50 | 0.0718390804597701 | 2 |
| SLITRK6-203 | SLITRK6 | Q9H5Y7 | SLIT and NTRK-like protein 6 | chr13 | GO:0035264 | Not Cancer Driver | No | 184 | 0.2187871581450653 | 226 | 44 | 0.0523186682520808 | 0 |
| SMO-201 | SMO | Q99835 | Protein smoothened | chr7 | GO:0035264 | Census, Compendium | Yes | 88 | 0.1118170266836086 | 242 | 20 | 0.025412960609911 | 1 |
| SMPD3-201 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0035264 | Not Cancer Driver | No | 73 | 0.1114503816793893 | 224 | 26 | 0.0396946564885496 | 0 |
| SOS1-202 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0035264 | Compendium | Yes | 155 | 0.1162790697674418 | 459 | 47 | 0.0352588147036759 | 32 |
| SPTBN2-208 | SPTBN2 | O15020 | Spectrin beta chain, non-erythrocytic 2 | chr11 | GO:0035264 | Not Cancer Driver | No | 233 | 0.0974895397489539 | 879 | 90 | 0.0376569037656903 | 2 |
| STIL-202 | STIL | Q15468 | SCL-interrupting locus protein | chr1 | GO:0035264 | Census, Compendium | Yes | 106 | 0.0823620823620823 | 735 | 64 | 0.0497280497280497 | 1 |
| STK40-204 | STK40 | Q8N2I9 | Serine/threonine-protein kinase 40 | chr1 | GO:0035264 | Not Cancer Driver | No | 37 | 0.0850574712643678 | 104 | 6 | 0.0137931034482758 | 0 |
| TAF10-201 | TAF10 | Q12962 | Transcription initiation factor TFIID subunit 10 | chr11 | GO:0035264 | Not Cancer Driver | No | 10 | 0.0458715596330275 | 131 | 2 | 0.0091743119266055 | 0 |
| TAL2-201 | TAL2 | Q16559 | T-cell acute lymphocytic leukemia protein 2 | chr9 | GO:0035264 | Census | Yes | 11 | 0.1018518518518518 | 81 | 8 | 0.074074074074074 | 0 |
| TBL1XR1-214 | TBL1XR1 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | chr3 | GO:0035264 | Census, Compendium | Yes | 68 | 0.1322957198443579 | 136 | 14 | 0.0272373540856031 | 4 |
| TMED2-201 | TMED2 | Q15363 | Transmembrane emp24 domain-containing protein 2 | chr12 | GO:0035264 | Not Cancer Driver | No | 16 | 0.0796019900497512 | 25 | 2 | 0.0099502487562189 | 0 |
| TNS2-201 | TNS2 | Q63HR2 | Tensin-2 | chr12 | GO:0035264 | Not Cancer Driver | No | 97 | 0.0688431511710433 | 800 | 47 | 0.0333569907735983 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0035264 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TTC8-201 | TTC8 | Q8TAM2 | Tetratricopeptide repeat protein 8 | chr14 | GO:0035264 | Not Cancer Driver | No | 54 | 0.1016949152542373 | 78 | 11 | 0.0207156308851224 | 0 |
| WDR11-201 | WDR11 | Q9BZH6 | WD repeat-containing protein 11 | chr10 | GO:0035264 | Not Cancer Driver | No | 100 | 0.0816993464052287 | 94 | 6 | 0.0049019607843137 | 6 |
| WDR48-201 | WDR48 | Q8TAF3 | WD repeat-containing protein 48 | chr3 | GO:0035264 | Not Cancer Driver | No | 48 | 0.0709010339734121 | 125 | 16 | 0.0236336779911373 | 0 |
| WDTC1-201 | WDTC1 | Q8N5D0 | WD and tetratricopeptide repeats protein 1 | chr1 | GO:0035264 | Not Cancer Driver | No | 66 | 0.0974889217134416 | 154 | 19 | 0.0280649926144756 | 0 |
| WWTR1-201 | WWTR1 | Q9GZV5 | WW domain-containing transcription regulator protein 1 | chr3 | GO:0035264 | Census | Yes | 29 | 0.0725 | 389 | 29 | 0.0725 | 0 |
| XRCC2-201 | XRCC2 | O43543 | DNA repair protein XRCC2 | chr7 | GO:0035264 | Not Cancer Driver | No | 27 | 0.0964285714285714 | 9 | 0 | 0.0 | 2 |
| ZFP36L1-202 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0035264 | Compendium | Yes | 50 | 0.1479289940828402 | 212 | 26 | 0.0769230769230769 | 0 |
| ZFX-201 | ZFX | P17010 | Zinc finger X-chromosomal protein | chrX | GO:0035264 | Compendium | Yes | 68 | 0.084472049689441 | 370 | 25 | 0.031055900621118 | 0 |
| ZMPSTE24-201 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0035264 | Not Cancer Driver | No | 46 | 0.0968421052631579 | 23 | 0 | 0.0 | 3 |