Total number of protein in "GO:0035591" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1-207 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | GO:0035591 | Census, Compendium | Yes | 37 | 0.0728346456692913 | 360 | 28 | 0.0551181102362204 | 0 |
| ABI2-203 | ABI2 | Q9NYB9 | Abl interactor 2 | chr2 | GO:0035591 | Not Cancer Driver | No | 46 | 0.084870848708487 | 377 | 30 | 0.055350553505535 | 0 |
| ABI3-201 | ABI3 | Q9P2A4 | ABI gene family member 3 | chr17 | GO:0035591 | Not Cancer Driver | No | 36 | 0.0983606557377049 | 249 | 23 | 0.0628415300546448 | 0 |
| AIM2-202 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0035591 | Not Cancer Driver | No | 54 | 0.1574344023323615 | 79 | 17 | 0.0495626822157434 | 0 |
| ARF6-201 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | GO:0035591 | Not Cancer Driver | No | 16 | 0.0914285714285714 | 5 | 0 | 0.0 | 0 |
| AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0035591 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
| BANK1-201 | BANK1 | Q8NDB2 | B-cell scaffold protein with ankyrin repeats | chr4 | GO:0035591 | Not Cancer Driver | No | 109 | 0.1388535031847133 | 395 | 58 | 0.0738853503184713 | 0 |
| BLNK-201 | BLNK | Q8WV28 | B-cell linker protein | chr10 | GO:0035591 | Not Cancer Driver | No | 54 | 0.1184210526315789 | 380 | 48 | 0.1052631578947368 | 0 |
| CAPRIN1-201 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | GO:0035591 | Not Cancer Driver | No | 63 | 0.0888575458392101 | 603 | 52 | 0.0733427362482369 | 0 |
| CDC42SE2-208 | CDC42SE2 | Q9NRR3 | CDC42 small effector protein 2 | chr5 | GO:0035591 | Not Cancer Driver | No | 0 | 0.0 | 57 | 0 | 0.0 | 0 |
| CRK-201 | CRK | P46108 | Adapter molecule crk | chr17 | GO:0035591 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 197 | 19 | 0.0625 | 0 |
| CRKL-201 | CRKL | P46109 | Crk-like protein | chr22 | GO:0035591 | Not Cancer Driver | No | 24 | 0.0792079207920792 | 160 | 17 | 0.0561056105610561 | 0 |
| DAB2IP-203 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0035591 | Not Cancer Driver | No | 95 | 0.0798990748528175 | 682 | 49 | 0.04121110176619 | 0 |
| DDX3X-244 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0035591 | Census, Compendium | Yes | 91 | 0.1374622356495468 | 302 | 32 | 0.0483383685800604 | 18 |
| FADD-201 | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0035591 | Not Cancer Driver | No | 24 | 0.1153846153846153 | 45 | 9 | 0.0432692307692307 | 1 |
| FCRL2-201 | FCRL2 | Q96LA5 | Fc receptor-like protein 2 | chr1 | GO:0035591 | Not Cancer Driver | No | 91 | 0.1791338582677165 | 77 | 6 | 0.0118110236220472 | 0 |
| FMR1-205 | FMR1 | Q06787 | Fragile X messenger ribonucleoprotein 1 | chrX | GO:0035591 | Not Cancer Driver | No | 92 | 0.1455696202531645 | 327 | 50 | 0.0791139240506329 | 3 |
| GAB1-201 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | GO:0035591 | Not Cancer Driver | No | 54 | 0.0778097982708933 | 570 | 46 | 0.0662824207492795 | 1 |
| GAB3-202 | GAB3 | Q8WWW8 | GRB2-associated-binding protein 3 | chrX | GO:0035591 | Not Cancer Driver | No | 63 | 0.1075085324232082 | 390 | 46 | 0.0784982935153583 | 0 |
| GRAPL-201 | GRAPL | Q8TC17 | GRB2-related adapter protein-like | chr17 | GO:0035591 | Not Cancer Driver | No | 0 | 0.0 | 26 | 0 | 0.0 | 0 |
| HAX1-201 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | GO:0035591 | Not Cancer Driver | No | 30 | 0.1075268817204301 | 219 | 23 | 0.082437275985663 | 2 |
| HCLS1-201 | HCLS1 | P14317 | Hematopoietic lineage cell-specific protein | chr3 | GO:0035591 | Not Cancer Driver | No | 81 | 0.1666666666666666 | 448 | 75 | 0.1543209876543209 | 0 |
| HOMER1-202 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | GO:0035591 | Not Cancer Driver | No | 32 | 0.0903954802259887 | 243 | 28 | 0.0790960451977401 | 0 |
| IKBKG-206 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | GO:0035591 | Not Cancer Driver | No | 5 | 0.0119331742243436 | 301 | 4 | 0.0095465393794749 | 21 |
| IRAK1BP1-201 | IRAK1BP1 | Q5VVH5 | Interleukin-1 receptor-associated kinase 1-binding protein 1 | chr6 | GO:0035591 | Not Cancer Driver | No | 20 | 0.0769230769230769 | 108 | 10 | 0.0384615384615384 | 0 |
| IRAK2-201 | IRAK2 | O43187 | Interleukin-1 receptor-associated kinase-like 2 | chr3 | GO:0035591 | Not Cancer Driver | No | 56 | 0.0896 | 203 | 21 | 0.0336 | 0 |
| KHDRBS1-202 | KHDRBS1 | Q07666 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | chr1 | GO:0035591 | Not Cancer Driver | No | 42 | 0.0948081264108352 | 362 | 37 | 0.0835214446952596 | 0 |
| LDLRAP1-201 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0035591 | Not Cancer Driver | No | 29 | 0.0941558441558441 | 121 | 9 | 0.0292207792207792 | 2 |
| MAVS-202 | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | GO:0035591 | Not Cancer Driver | No | 55 | 0.1018518518518518 | 415 | 44 | 0.0814814814814814 | 0 |
| MPP7-209 | MPP7 | Q5T2T1 | MAGUK p55 subfamily member 7 | chr10 | GO:0035591 | Not Cancer Driver | No | 105 | 0.1822916666666666 | 199 | 60 | 0.1041666666666666 | 0 |
| MYD88-209 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0035591 | Census, Compendium | Yes | 29 | 0.0979729729729729 | 47 | 2 | 0.0067567567567567 | 2 |
| NCK1-207 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0035591 | Not Cancer Driver | No | 41 | 0.1087533156498673 | 111 | 15 | 0.039787798408488 | 0 |
| NCK2-201 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0035591 | Not Cancer Driver | No | 66 | 0.1736842105263158 | 88 | 15 | 0.0394736842105263 | 0 |
| NLRP1-208 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0035591 | Not Cancer Driver | No | 169 | 0.1147318397827562 | 341 | 45 | 0.0305498981670061 | 6 |
| NLRP3-201 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0035591 | Not Cancer Driver | No | 287 | 0.2775628626692456 | 65 | 30 | 0.0290135396518375 | 34 |
| NLRP6-201 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0035591 | Not Cancer Driver | No | 68 | 0.0762331838565022 | 205 | 11 | 0.0123318385650224 | 0 |
| NOS1AP-201 | NOS1AP | O75052 | Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein | chr1 | GO:0035591 | Not Cancer Driver | No | 76 | 0.150197628458498 | 257 | 46 | 0.0909090909090909 | 1 |
| PAG1-201 | PAG1 | Q9NWQ8 | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 | chr8 | GO:0035591 | Not Cancer Driver | No | 44 | 0.1018518518518518 | 399 | 44 | 0.1018518518518518 | 0 |
| RACK1-227 | RACK1 | P63244 | Small ribosomal subunit protein RACK1 | chr5 | GO:0035591 | Not Cancer Driver | No | 27 | 0.085173501577287 | 13 | 0 | 0.0 | 0 |
| RIPK1-201 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0035591 | Compendium | Yes | 59 | 0.0879284649776453 | 277 | 28 | 0.0417287630402384 | 1 |
| RIPK2-201 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0035591 | Not Cancer Driver | No | 43 | 0.0796296296296296 | 143 | 14 | 0.0259259259259259 | 0 |
| SARM1-208 | SARM1 | Q6SZW1 | NAD(+) hydrolase SARM1 | chr17 | GO:0035591 | Not Cancer Driver | No | 32 | 0.0441988950276243 | 80 | 4 | 0.005524861878453 | 0 |
| SCRIB-201 | SCRIB | Q14160 | Protein scribble homolog | chr8 | GO:0035591 | Not Cancer Driver | No | 169 | 0.103680981595092 | 1071 | 117 | 0.0717791411042944 | 2 |
| SH2B2-201 | SH2B2 | O14492 | SH2B adapter protein 2 | chr7 | GO:0035591 | Not Cancer Driver | No | 32 | 0.050632911392405 | 356 | 12 | 0.0189873417721519 | 0 |
| SLA2-201 | SLA2 | Q9H6Q3 | Src-like-adapter 2 | chr20 | GO:0035591 | Not Cancer Driver | No | 26 | 0.0996168582375478 | 43 | 4 | 0.0153256704980842 | 0 |
| STAP1-201 | STAP1 | Q9ULZ2 | Signal-transducing adaptor protein 1 | chr4 | GO:0035591 | Not Cancer Driver | No | 46 | 0.1559322033898305 | 105 | 12 | 0.0406779661016949 | 0 |
| STAP2-201 | STAP2 | Q9UGK3 | Signal-transducing adaptor protein 2 | chr19 | GO:0035591 | Not Cancer Driver | No | 30 | 0.0744416873449131 | 178 | 11 | 0.0272952853598014 | 0 |
| STAT3-201 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0035591 | Census, Compendium | Yes | 93 | 0.1207792207792207 | 152 | 16 | 0.0207792207792207 | 15 |
| STING1-201 | STING1 | Q86WV6 | Stimulator of interferon genes protein | chr5 | GO:0035591 | Not Cancer Driver | No | 39 | 0.1029023746701846 | 66 | 12 | 0.0316622691292876 | 4 |
| TICAM1-201 | TICAM1 | Q8IUC6 | TIR domain-containing adapter molecule 1 | chr19 | GO:0035591 | Not Cancer Driver | No | 75 | 0.1053370786516853 | 445 | 50 | 0.0702247191011236 | 1 |
| TIRAP-202 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0035591 | Not Cancer Driver | No | 14 | 0.0633484162895927 | 80 | 5 | 0.0226244343891402 | 0 |
| TRAF2-201 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0035591 | Not Cancer Driver | No | 51 | 0.1017964071856287 | 4 | 1 | 0.0019960079840319 | 0 |
| WDR59-201 | WDR59 | Q6PJI9 | GATOR complex protein WDR59 | chr16 | GO:0035591 | Not Cancer Driver | No | 98 | 0.1006160164271047 | 204 | 28 | 0.028747433264887 | 0 |
| YWHAE-201 | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | GO:0035591 | Census | Yes | 24 | 0.0941176470588235 | 41 | 1 | 0.0039215686274509 | 0 |
| ZDHHC11-201 | ZDHHC11 | Q9H8X9 | Palmitoyltransferase ZDHHC11 | chr5 | GO:0035591 | Not Cancer Driver | No | 40 | 0.0970873786407767 | 76 | 15 | 0.0364077669902912 | 0 |