Total number of protein in "GO:0035861" GO term: 92
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTR2-201 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | GO:0035861 | Not Cancer Driver | No | 28 | 0.0710659898477157 | 6 | 1 | 0.0025380710659898 | 0 |
| ACTR3-201 | ACTR3 | P61158 | Actin-related protein 3 | chr2 | GO:0035861 | Not Cancer Driver | No | 24 | 0.0574162679425837 | 16 | 2 | 0.0047846889952153 | 0 |
| AIM2-202 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0035861 | Not Cancer Driver | No | 54 | 0.1574344023323615 | 79 | 17 | 0.0495626822157434 | 0 |
| APLF-201 | APLF | Q8IW19 | Aprataxin and PNK-like factor | chr2 | GO:0035861 | Not Cancer Driver | No | 43 | 0.0841487279843444 | 411 | 37 | 0.0724070450097847 | 0 |
| ARPC1A-201 | ARPC1A | Q92747 | Actin-related protein 2/3 complex subunit 1A | chr7 | GO:0035861 | Not Cancer Driver | No | 39 | 0.1054054054054054 | 27 | 7 | 0.0189189189189189 | 0 |
| ARPC2-202 | ARPC2 | O15144 | Actin-related protein 2/3 complex subunit 2 | chr2 | GO:0035861 | Not Cancer Driver | No | 29 | 0.0966666666666666 | 49 | 7 | 0.0233333333333333 | 0 |
| ARPC3-201 | ARPC3 | O15145 | Actin-related protein 2/3 complex subunit 3 | chr12 | GO:0035861 | Not Cancer Driver | No | 10 | 0.0561797752808988 | 26 | 5 | 0.0280898876404494 | 0 |
| ARPC4-201 | ARPC4 | P59998 | Actin-related protein 2/3 complex subunit 4 | chr3 | GO:0035861 | Not Cancer Driver | No | 11 | 0.0654761904761904 | 3 | 0 | 0.0 | 1 |
| ARPC5-202 | ARPC5 | O15511 | Actin-related protein 2/3 complex subunit 5 | chr1 | GO:0035861 | Not Cancer Driver | No | 11 | 0.0728476821192053 | 67 | 5 | 0.0331125827814569 | 0 |
| ASF1A-201 | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | GO:0035861 | Not Cancer Driver | No | 11 | 0.0539215686274509 | 69 | 2 | 0.0098039215686274 | 0 |
| ATF2-201 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0035861 | Not Cancer Driver | No | 42 | 0.0831683168316831 | 451 | 36 | 0.0712871287128712 | 0 |
| CGAS-201 | CGAS | Q8N884 | Cyclic GMP-AMP synthase | chr6 | GO:0035861 | Not Cancer Driver | No | 33 | 0.0632183908045977 | 175 | 6 | 0.0114942528735632 | 0 |
| CHD1L-202 | CHD1L | Q86WJ1 | Chromodomain-helicase-DNA-binding protein 1-like | chr1 | GO:0035861 | Not Cancer Driver | No | 75 | 0.0836120401337792 | 226 | 21 | 0.0234113712374581 | 0 |
| CNTD1-204 | CNTD1 | Q8N815 | Cyclin N-terminal domain-containing protein 1 | chr17 | GO:0035861 | Not Cancer Driver | No | 24 | 0.0727272727272727 | 30 | 1 | 0.003030303030303 | 0 |
| CYREN-201 | CYREN | Q9BWK5 | Cell cycle regulator of non-homologous end joining | chr7 | GO:0035861 | Not Cancer Driver | No | 12 | 0.0764331210191082 | 128 | 11 | 0.0700636942675159 | 0 |
| DDB1-201 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0035861 | Not Cancer Driver | No | 98 | 0.0859649122807017 | 50 | 8 | 0.0070175438596491 | 3 |
| DMC1-201 | DMC1 | Q14565 | Meiotic recombination protein DMC1/LIM15 homolog | chr22 | GO:0035861 | Not Cancer Driver | No | 28 | 0.0823529411764705 | 49 | 5 | 0.0147058823529411 | 0 |
| ENST00000640655 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0035861 | Not Cancer Driver | No | 92 | 0.0758450123660346 | 721 | 45 | 0.0370981038746908 | 0 |
| EPC1-201 | EPC1 | Q9H2F5 | Enhancer of polycomb homolog 1 | chr10 | GO:0035861 | Not Cancer Driver | No | 84 | 0.1004784688995215 | 518 | 55 | 0.0657894736842105 | 0 |
| ESCO2-201 | ESCO2 | Q56NI9 | N-acetyltransferase ESCO2 | chr8 | GO:0035861 | Not Cancer Driver | No | 42 | 0.0698835274542429 | 293 | 18 | 0.0299500831946755 | 1 |
| H2AX-202 | H2AX | P16104 | Histone H2AX | chr11 | GO:0035861 | Not Cancer Driver | No | 19 | 0.1328671328671328 | 68 | 8 | 0.0559440559440559 | 0 |
| HELB-201 | HELB | Q8NG08 | DNA helicase B | chr12 | GO:0035861 | Not Cancer Driver | No | 96 | 0.0883164673413063 | 302 | 24 | 0.0220791168353265 | 0 |
| HTATSF1-201 | HTATSF1 | O43719 | HIV Tat-specific factor 1 | chrX | GO:0035861 | Not Cancer Driver | No | 78 | 0.1033112582781456 | 575 | 57 | 0.0754966887417218 | 0 |
| HUS1-201 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | GO:0035861 | Not Cancer Driver | No | 19 | 0.0678571428571428 | 17 | 1 | 0.0035714285714285 | 0 |
| HUS1B-201 | HUS1B | Q8NHY5 | Checkpoint protein HUS1B | chr6 | GO:0035861 | Not Cancer Driver | No | 35 | 0.1258992805755395 | 10 | 1 | 0.0035971223021582 | 0 |
| IFFO1-204 | IFFO1 | Q0D2I5 | Non-homologous end joining factor IFFO1 | chr12 | GO:0035861 | Not Cancer Driver | No | 38 | 0.0679785330948121 | 363 | 22 | 0.0393559928443649 | 0 |
| INIP-203 | INIP | Q9NRY2 | SOSS complex subunit C | chr9 | GO:0035861 | Not Cancer Driver | No | 14 | 0.1346153846153846 | 79 | 9 | 0.0865384615384615 | 0 |
| INTS3-201 | INTS3 | Q68E01 | Integrator complex subunit 3 | chr1 | GO:0035861 | Not Cancer Driver | No | 91 | 0.0873320537428023 | 213 | 19 | 0.0182341650671785 | 0 |
| KAT5-203 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | GO:0035861 | Not Cancer Driver | No | 45 | 0.087719298245614 | 174 | 16 | 0.0311890838206627 | 3 |
| KDM4D-201 | KDM4D | Q6B0I6 | Lysine-specific demethylase 4D | chr11 | GO:0035861 | Not Cancer Driver | No | 66 | 0.1261950286806883 | 215 | 24 | 0.0458891013384321 | 0 |
| LMNA-205 | LMNA | P02545 | Prelamin-A/C | chr1 | GO:0035861 | Census | Yes | 50 | 0.0753012048192771 | 547 | 34 | 0.0512048192771084 | 117 |
| MAD2L2-207 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0035861 | Not Cancer Driver | No | 16 | 0.0758293838862559 | 0 | 0 | 0.0 | 1 |
| MBTD1-204 | MBTD1 | Q05BQ5 | MBT domain-containing protein 1 | chr17 | GO:0035861 | Not Cancer Driver | No | 52 | 0.0828025477707006 | 119 | 6 | 0.0095541401273885 | 0 |
| MDC1-201 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | GO:0035861 | Not Cancer Driver | No | 175 | 0.0837721397797989 | 1829 | 156 | 0.0746768788894207 | 0 |
| MMS22L-213 | MMS22L | Q6ZRQ5 | Protein MMS22-like | chr6 | GO:0035861 | Not Cancer Driver | No | 131 | 0.1053901850362027 | 13 | 1 | 0.0008045052292839 | 0 |
| MRE11-201 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0035861 | Not Cancer Driver | No | 61 | 0.0861581920903954 | 292 | 28 | 0.03954802259887 | 1 |
| NABP1-205 | NABP1 | Q96AH0 | SOSS complex subunit B2 | chr2 | GO:0035861 | Not Cancer Driver | No | 20 | 0.0980392156862745 | 102 | 8 | 0.0392156862745098 | 0 |
| NABP2-201 | NABP2 | Q9BQ15 | SOSS complex subunit B1 | chr12 | GO:0035861 | Not Cancer Driver | No | 22 | 0.1042654028436018 | 125 | 14 | 0.0663507109004739 | 0 |
| NBN-201 | NBN | O60934 | Nibrin | chr8 | GO:0035861 | Census | Yes | 63 | 0.0835543766578249 | 420 | 45 | 0.059681697612732 | 1 |
| NHEJ1-201 | NHEJ1 | Q9H9Q4 | Non-homologous end-joining factor 1 | chr2 | GO:0035861 | Not Cancer Driver | No | 21 | 0.0702341137123745 | 83 | 6 | 0.020066889632107 | 2 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0035861 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PARP3-201 | PARP3 | Q9Y6F1 | Protein mono-ADP-ribosyltransferase PARP3 | chr3 | GO:0035861 | Not Cancer Driver | No | 48 | 0.0900562851782364 | 272 | 27 | 0.0506566604127579 | 0 |
| PAXX-201 | PAXX | Q9BUH6 | Protein PAXX | chr9 | GO:0035861 | Not Cancer Driver | No | 16 | 0.0784313725490196 | 121 | 12 | 0.0588235294117647 | 0 |
| PHF1-202 | PHF1 | O43189 | PHD finger protein 1 | chr6 | GO:0035861 | Not Cancer Driver | No | 47 | 0.0828924162257495 | 277 | 23 | 0.0405643738977072 | 0 |
| PNKP-201 | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | GO:0035861 | Not Cancer Driver | No | 46 | 0.0882917466410748 | 177 | 21 | 0.0403071017274472 | 4 |
| POLH-202 | POLH | Q9Y253 | DNA polymerase eta | chr6 | GO:0035861 | Not Cancer Driver | No | 49 | 0.0687237026647966 | 291 | 15 | 0.0210378681626928 | 10 |
| POLL-203 | POLL | Q9UGP5 | DNA polymerase lambda | chr10 | GO:0035861 | Not Cancer Driver | No | 57 | 0.0991304347826086 | 215 | 13 | 0.0226086956521739 | 0 |
| POLQ-201 | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0035861 | Census, Compendium | Yes | 274 | 0.1057915057915057 | 956 | 94 | 0.0362934362934362 | 0 |
| PRPF19-201 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0035861 | Not Cancer Driver | No | 43 | 0.0853174603174603 | 110 | 12 | 0.0238095238095238 | 0 |
| RAD18-201 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | GO:0035861 | Not Cancer Driver | No | 42 | 0.0848484848484848 | 330 | 31 | 0.0626262626262626 | 0 |
| RAD50-201 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0035861 | Not Cancer Driver | No | 106 | 0.0807926829268292 | 730 | 50 | 0.0381097560975609 | 0 |
| RAD51-201 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0035861 | Not Cancer Driver | No | 27 | 0.079646017699115 | 48 | 3 | 0.0088495575221238 | 3 |
| RFWD3-201 | RFWD3 | Q6PCD5 | E3 ubiquitin-protein ligase RFWD3 | chr16 | GO:0035861 | Census | Yes | 59 | 0.0762273901808785 | 319 | 26 | 0.0335917312661498 | 1 |
| RHNO1-204 | RHNO1 | Q9BSD3 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 | chr12 | GO:0035861 | Not Cancer Driver | No | 22 | 0.0924369747899159 | 193 | 18 | 0.0756302521008403 | 0 |
| RIF1-205 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:0035861 | Not Cancer Driver | No | 194 | 0.0784789644012945 | 1364 | 112 | 0.0453074433656957 | 0 |
| RNF138-202 | RNF138 | Q8WVD3 | E3 ubiquitin-protein ligase RNF138 | chr18 | GO:0035861 | Not Cancer Driver | No | 32 | 0.1306122448979592 | 35 | 5 | 0.0204081632653061 | 0 |
| RNF168-201 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | GO:0035861 | Not Cancer Driver | No | 66 | 0.1155866900175131 | 473 | 56 | 0.0980735551663747 | 0 |
| RNF169-201 | RNF169 | Q8NCN4 | E3 ubiquitin-protein ligase RNF169 | chr11 | GO:0035861 | Not Cancer Driver | No | 41 | 0.057909604519774 | 638 | 40 | 0.0564971751412429 | 0 |
| RNF8-202 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0035861 | Not Cancer Driver | No | 31 | 0.0639175257731958 | 226 | 14 | 0.0288659793814433 | 0 |
| RPA1-201 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0035861 | Not Cancer Driver | No | 45 | 0.073051948051948 | 98 | 7 | 0.0113636363636363 | 1 |
| RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0035861 | Not Cancer Driver | No | 20 | 0.074074074074074 | 117 | 12 | 0.0444444444444444 | 0 |
| RPA3-201 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | GO:0035861 | Not Cancer Driver | No | 10 | 0.0826446280991735 | 4 | 1 | 0.0082644628099173 | 0 |
| RPA4-201 | RPA4 | Q13156 | Replication protein A 30 kDa subunit | chrX | GO:0035861 | Not Cancer Driver | No | 56 | 0.21455938697318 | 59 | 10 | 0.0383141762452107 | 0 |
| SAMHD1-221 | SAMHD1 | Q9Y3Z3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | chr20 | GO:0035861 | Not Cancer Driver | No | 80 | 0.1277955271565495 | 91 | 9 | 0.0143769968051118 | 12 |
| SETMAR-201 | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:0035861 | Not Cancer Driver | No | 44 | 0.0643274853801169 | 155 | 11 | 0.0160818713450292 | 0 |
| SHLD1-201 | SHLD1 | Q8IYI0 | Shieldin complex subunit 1 | chr20 | GO:0035861 | Not Cancer Driver | No | 25 | 0.1219512195121951 | 118 | 18 | 0.0878048780487804 | 0 |
| SHLD2-201 | SHLD2 | Q86V20 | Shieldin complex subunit 2 | chr10 | GO:0035861 | Not Cancer Driver | No | 51 | 0.0610778443113772 | 156 | 5 | 0.0059880239520958 | 0 |
| SHLD3-201 | SHLD3 | Q6ZNX1 | Shieldin complex subunit 3 | chr5 | GO:0035861 | Not Cancer Driver | No | 2 | 0.008 | 82 | 1 | 0.004 | 0 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0035861 | Not Cancer Driver | No | 24 | 0.0676056338028169 | 165 | 6 | 0.0169014084507042 | 0 |
| SIRT7-201 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | GO:0035861 | Not Cancer Driver | No | 34 | 0.085 | 163 | 10 | 0.025 | 0 |
| SLF1-201 | SLF1 | Q9BQI6 | SMC5-SMC6 complex localization factor protein 1 | chr5 | GO:0035861 | Not Cancer Driver | No | 70 | 0.0661625708884688 | 167 | 8 | 0.0075614366729678 | 0 |
| SLF2-201 | SLF2 | Q8IX21 | SMC5-SMC6 complex localization factor protein 2 | chr10 | GO:0035861 | Not Cancer Driver | No | 83 | 0.0707587382779198 | 726 | 58 | 0.0494458653026428 | 1 |
| SMARCA5-201 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | GO:0035861 | Not Cancer Driver | No | 73 | 0.0693916349809885 | 364 | 26 | 0.0247148288973384 | 0 |
| SMARCAD1-201 | SMARCAD1 | Q9H4L7 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 | chr4 | GO:0035861 | Not Cancer Driver | No | 86 | 0.0838206627680311 | 389 | 37 | 0.0360623781676413 | 0 |
| SMARCAL1-201 | SMARCAL1 | Q9NZC9 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 | chr2 | GO:0035861 | Not Cancer Driver | No | 98 | 0.1027253668763102 | 340 | 37 | 0.0387840670859538 | 10 |
| SMC5-201 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0035861 | Not Cancer Driver | No | 94 | 0.0853769300635785 | 381 | 35 | 0.0317892824704813 | 1 |
| SMC6-207 | SMC6 | Q96SB8 | Structural maintenance of chromosomes protein 6 | chr2 | GO:0035861 | Not Cancer Driver | No | 95 | 0.0870760769935838 | 459 | 43 | 0.0394133822181484 | 0 |
| SMCHD1-201 | SMCHD1 | A6NHR9 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | chr18 | GO:0035861 | Not Cancer Driver | No | 166 | 0.0827930174563591 | 345 | 34 | 0.0169576059850374 | 42 |
| TIMELESS-203 | TIMELESS | Q9UNS1 | Protein timeless homolog | chr12 | GO:0035861 | Not Cancer Driver | No | 127 | 0.1051324503311258 | 371 | 44 | 0.0364238410596026 | 0 |
| TONSL-201 | TONSL | Q96HA7 | Tonsoku-like protein | chr8 | GO:0035861 | Not Cancer Driver | No | 127 | 0.0921625544267053 | 550 | 53 | 0.0384615384615384 | 8 |
| TOPBP1-201 | TOPBP1 | Q92547 | DNA topoisomerase 2-binding protein 1 | chr3 | GO:0035861 | Not Cancer Driver | No | 121 | 0.0795006570302234 | 579 | 43 | 0.0282522996057818 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0035861 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TP53BP1-201 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0035861 | Not Cancer Driver | No | 159 | 0.0806288032454361 | 1638 | 131 | 0.0664300202839756 | 0 |
| UFL1-201 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0035861 | Not Cancer Driver | No | 77 | 0.096977329974811 | 141 | 19 | 0.0239294710327455 | 0 |
| UIMC1-212 | UIMC1 | Q96RL1 | BRCA1-A complex subunit RAP80 | chr5 | GO:0035861 | Not Cancer Driver | No | 38 | 0.0528511821974965 | 610 | 31 | 0.043115438108484 | 0 |
| VCP-201 | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0035861 | Not Cancer Driver | No | 74 | 0.0918114143920595 | 186 | 14 | 0.0173697270471464 | 12 |
| WAS-201 | WAS | P42768 | Actin nucleation-promoting factor WAS | chrX | GO:0035861 | Census, Compendium | Yes | 44 | 0.0876494023904382 | 400 | 28 | 0.0557768924302788 | 28 |
| WDR70-201 | WDR70 | Q9NW82 | WD repeat-containing protein 70 | chr5 | GO:0035861 | Not Cancer Driver | No | 75 | 0.1146788990825688 | 363 | 48 | 0.073394495412844 | 0 |
| WRAP53-202 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0035861 | Not Cancer Driver | No | 46 | 0.083941605839416 | 234 | 21 | 0.0383211678832116 | 4 |
| XRCC4-205 | XRCC4 | Q13426 | DNA repair protein XRCC4 | chr5 | GO:0035861 | Not Cancer Driver | No | 33 | 0.0982142857142857 | 173 | 23 | 0.0684523809523809 | 3 |
| ZBTB7A-201 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | GO:0035861 | Not Cancer Driver | No | 50 | 0.0856164383561643 | 286 | 26 | 0.0445205479452054 | 2 |
| ZGRF1-208 | ZGRF1 | Q86YA3 | Protein ZGRF1 | chr4 | GO:0035861 | Not Cancer Driver | No | 147 | 0.0698669201520912 | 883 | 68 | 0.0323193916349809 | 0 |