Total number of protein in "GO:0042110" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADA-201 | ADA | P00813 | Adenosine deaminase | chr20 | GO:0042110 | Not Cancer Driver | No | 43 | 0.1184573002754821 | 45 | 9 | 0.024793388429752 | 22 |
| AZI2-212 | AZI2 | Q9H6S1 | 5-azacytidine-induced protein 2 | chr3 | GO:0042110 | Not Cancer Driver | No | 24 | 0.0612244897959183 | 192 | 10 | 0.0255102040816326 | 0 |
| CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0042110 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
| CD2-202 | CD2 | P06729 | T-cell surface antigen CD2 | chr1 | GO:0042110 | Not Cancer Driver | No | 54 | 0.1538461538461538 | 126 | 30 | 0.0854700854700854 | 0 |
| CD276-202 | CD276 | Q5ZPR3 | CD276 antigen | chr15 | GO:0042110 | Not Cancer Driver | No | 47 | 0.0880149812734082 | 140 | 8 | 0.0149812734082397 | 0 |
| CD28-201 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0042110 | Census | Yes | 26 | 0.1181818181818181 | 18 | 6 | 0.0272727272727272 | 0 |
| CD3E-201 | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | GO:0042110 | Not Cancer Driver | No | 16 | 0.0772946859903381 | 72 | 6 | 0.0289855072463768 | 0 |
| CD3G-206 | CD3G | P09693 | T-cell surface glycoprotein CD3 gamma chain | chr11 | GO:0042110 | Not Cancer Driver | No | 15 | 0.0824175824175824 | 49 | 5 | 0.0274725274725274 | 0 |
| CD4-201 | CD4 | P01730 | T-cell surface glycoprotein CD4 | chr12 | GO:0042110 | Not Cancer Driver | No | 50 | 0.1091703056768559 | 56 | 7 | 0.0152838427947598 | 0 |
| CD44-208 | CD44 | P16070 | CD44 antigen | chr11 | GO:0042110 | Not Cancer Driver | No | 58 | 0.0781671159029649 | 547 | 50 | 0.0673854447439353 | 0 |
| CD7-201 | CD7 | P09564 | T-cell antigen CD7 | chr17 | GO:0042110 | Not Cancer Driver | No | 21 | 0.0875 | 74 | 6 | 0.025 | 0 |
| CD80-201 | CD80 | P33681 | T-lymphocyte activation antigen CD80 | chr3 | GO:0042110 | Not Cancer Driver | No | 33 | 0.1145833333333333 | 27 | 1 | 0.0034722222222222 | 0 |
| CD84-201 | CD84 | Q9UIB8 | SLAM family member 5 | chr1 | GO:0042110 | Not Cancer Driver | No | 63 | 0.1826086956521739 | 52 | 8 | 0.0231884057971014 | 0 |
| CD86-202 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:0042110 | Not Cancer Driver | No | 64 | 0.1945288753799392 | 56 | 10 | 0.0303951367781155 | 0 |
| CD8A-201 | CD8A | P01732 | T-cell surface glycoprotein CD8 alpha chain | chr2 | GO:0042110 | Not Cancer Driver | No | 27 | 0.1148936170212766 | 28 | 2 | 0.0085106382978723 | 1 |
| CD8B-203 | CD8B | P10966 | T-cell surface glycoprotein CD8 beta chain | chr2 | GO:0042110 | Not Cancer Driver | No | 33 | 0.1571428571428571 | 10 | 0 | 0.0 | 0 |
| CEACAM21-202 | CEACAM21 | Q3KPI0 | Carcinoembryonic antigen-related cell adhesion molecule 21 | chr19 | GO:0042110 | Not Cancer Driver | No | 41 | 0.1399317406143344 | 73 | 11 | 0.0375426621160409 | 0 |
| CLEC7A-202 | CLEC7A | Q9BXN2 | C-type lectin domain family 7 member A | chr12 | GO:0042110 | Not Cancer Driver | No | 31 | 0.1255060728744939 | 46 | 1 | 0.0040485829959514 | 0 |
| CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0042110 | Not Cancer Driver | No | 54 | 0.0711462450592885 | 102 | 2 | 0.0026350461133069 | 0 |
| DCAF12-201 | DCAF12 | Q5T6F0 | DDB1- and CUL4-associated factor 12 | chr9 | GO:0042110 | Not Cancer Driver | No | 46 | 0.1015452538631346 | 70 | 5 | 0.0110375275938189 | 0 |
| DDOST-201 | DDOST | P39656 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit | chr1 | GO:0042110 | Not Cancer Driver | No | 20 | 0.043859649122807 | 13 | 3 | 0.006578947368421 | 1 |
| DPP4-201 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | GO:0042110 | Not Cancer Driver | No | 108 | 0.1409921671018277 | 8 | 0 | 0.0 | 0 |
| FKBP1A-204 | FKBP1A | P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | chr20 | GO:0042110 | Not Cancer Driver | No | 11 | 0.1018518518518518 | 39 | 6 | 0.0555555555555555 | 0 |
| FOXP3-203 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | GO:0042110 | Not Cancer Driver | No | 29 | 0.0672853828306264 | 186 | 13 | 0.0301624129930394 | 10 |
| HSPD1-202 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0042110 | Not Cancer Driver | No | 45 | 0.0785340314136125 | 83 | 1 | 0.0017452006980802 | 2 |
| ICOSLG-204 | ICOSLG | O75144 | ICOS ligand | chr21 | GO:0042110 | Not Cancer Driver | No | 20 | 0.0662251655629139 | 29 | 2 | 0.0066225165562913 | 0 |
| IL4-201 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0042110 | Not Cancer Driver | No | 6 | 0.0392156862745098 | 0 | 0 | 0.0 | 0 |
| IRF4-201 | IRF4 | Q15306 | Interferon regulatory factor 4 | chr6 | GO:0042110 | Census, Compendium | Yes | 85 | 0.188470066518847 | 155 | 42 | 0.0931263858093126 | 0 |
| ITK-201 | ITK | Q08881 | Tyrosine-protein kinase ITK/TSK | chr5 | GO:0042110 | Census | Yes | 106 | 0.1709677419354838 | 43 | 9 | 0.014516129032258 | 1 |
| KIF13B-206 | KIF13B | Q9NQT8 | Kinesin-like protein KIF13B | chr8 | GO:0042110 | Not Cancer Driver | No | 131 | 0.0717415115005476 | 970 | 56 | 0.0306681270536692 | 0 |
| LAG3-201 | LAG3 | P18627 | Lymphocyte activation gene 3 protein | chr12 | GO:0042110 | Not Cancer Driver | No | 37 | 0.0704761904761904 | 208 | 10 | 0.019047619047619 | 0 |
| LAT-201 | LAT | O43561 | Linker for activation of T-cells family member 1 | chr16 | GO:0042110 | Not Cancer Driver | No | 20 | 0.0763358778625954 | 213 | 19 | 0.0725190839694656 | 0 |
| LY9-201 | LY9 | Q9HBG7 | T-lymphocyte surface antigen Ly-9 | chr1 | GO:0042110 | Not Cancer Driver | No | 109 | 0.166412213740458 | 250 | 39 | 0.0595419847328244 | 0 |
| MFAP3-212 | MFAP3 | P55082 | Microfibril-associated glycoprotein 3 | chr5 | GO:0042110 | Not Cancer Driver | No | 26 | 0.0718232044198895 | 95 | 8 | 0.0220994475138121 | 0 |
| NCK1-207 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0042110 | Not Cancer Driver | No | 41 | 0.1087533156498673 | 111 | 15 | 0.039787798408488 | 0 |
| NCK2-201 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0042110 | Not Cancer Driver | No | 66 | 0.1736842105263158 | 88 | 15 | 0.0394736842105263 | 0 |
| NLRC3-202 | NLRC3 | Q7RTR2 | NLR family CARD domain-containing protein 3 | chr16 | GO:0042110 | Not Cancer Driver | No | 136 | 0.1276995305164319 | 150 | 29 | 0.0272300469483568 | 0 |
| PIK3CD-202 | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0042110 | Not Cancer Driver | No | 116 | 0.1111111111111111 | 61 | 8 | 0.0076628352490421 | 1 |
| PIK3CG-205 | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0042110 | Not Cancer Driver | No | 230 | 0.2087114337568058 | 122 | 28 | 0.0254083484573502 | 3 |
| PPP3CA-203 | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0042110 | Compendium | Yes | 63 | 0.1209213051823416 | 140 | 24 | 0.0460652591170825 | 7 |
| PPP3CB-202 | PPP3CB | P16298 | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | chr10 | GO:0042110 | Not Cancer Driver | No | 47 | 0.0896946564885496 | 139 | 11 | 0.0209923664122137 | 0 |
| PTPRC-209 | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0042110 | Census, Compendium | Yes | 257 | 0.1967840735068912 | 462 | 91 | 0.0696784073506891 | 0 |
| RAB29-202 | RAB29 | O14966 | Ras-related protein Rab-7L1 | chr1 | GO:0042110 | Not Cancer Driver | No | 20 | 0.0985221674876847 | 18 | 3 | 0.0147783251231527 | 0 |
| RASGRP1-201 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0042110 | Not Cancer Driver | No | 70 | 0.0878293601003764 | 192 | 11 | 0.013801756587202 | 1 |
| RBX1-201 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0042110 | Not Cancer Driver | No | 9 | 0.0833333333333333 | 18 | 1 | 0.0092592592592592 | 0 |
| SLA2-201 | SLA2 | Q9H6Q3 | Src-like-adapter 2 | chr20 | GO:0042110 | Not Cancer Driver | No | 26 | 0.0996168582375478 | 43 | 4 | 0.0153256704980842 | 0 |
| SLAMF6-202 | SLAMF6 | Q96DU3 | SLAM family member 6 | chr1 | GO:0042110 | Not Cancer Driver | No | 59 | 0.1777108433734939 | 60 | 10 | 0.0301204819277108 | 0 |
| SLAMF7-203 | SLAMF7 | Q9NQ25 | SLAM family member 7 | chr1 | GO:0042110 | Not Cancer Driver | No | 43 | 0.1283582089552238 | 53 | 10 | 0.0298507462686567 | 0 |
| SLAMF9-202 | SLAMF9 | Q96A28 | SLAM family member 9 | chr1 | GO:0042110 | Not Cancer Driver | No | 47 | 0.1626297577854671 | 28 | 5 | 0.0173010380622837 | 0 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0042110 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| TNFAIP8L2-201 | TNFAIP8L2 | Q6P589 | Tumor necrosis factor alpha-induced protein 8-like protein 2 | chr1 | GO:0042110 | Not Cancer Driver | No | 27 | 0.1467391304347826 | 0 | 0 | 0.0 | 0 |
| TNFSF14-203 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0042110 | Not Cancer Driver | No | 44 | 0.1833333333333333 | 19 | 2 | 0.0083333333333333 | 0 |
| TREML2-201 | TREML2 | Q5T2D2 | Trem-like transcript 2 protein | chr6 | GO:0042110 | Not Cancer Driver | No | 47 | 0.146417445482866 | 126 | 22 | 0.0685358255451713 | 0 |
| WAS-201 | WAS | P42768 | Actin nucleation-promoting factor WAS | chrX | GO:0042110 | Census, Compendium | Yes | 44 | 0.0876494023904382 | 400 | 28 | 0.0557768924302788 | 28 |
| ZAP70-201 | ZAP70 | P43403 | Tyrosine-protein kinase ZAP-70 | chr2 | GO:0042110 | Not Cancer Driver | No | 90 | 0.1453957996768982 | 119 | 13 | 0.0210016155088853 | 7 |