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Total number of protein in "GO:0042593" GO term:  110

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACSM2A-209 ACSM2A Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial chr16 GO:0042593 Not Cancer Driver No 161 0.2790294627383015 49 21 0.0363951473136915 0
ADCY8-201 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0042593 Not Cancer Driver No 358 0.2861710631494804 215 31 0.0247801758593125 0
ADGRF5-202 ADGRF5 Q8IZF2 Adhesion G protein-coupled receptor F5 chr6 GO:0042593 Not Cancer Driver No 180 0.1337295690936107 53 7 0.0052005943536404 0
ADIPOQ-201 ADIPOQ Q15848 Adiponectin chr3 GO:0042593 Not Cancer Driver No 32 0.1311475409836065 92 16 0.0655737704918032 1
ADIPOR1-201 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0042593 Not Cancer Driver No 48 0.128 70 8 0.0213333333333333 0
ADIPOR2-201 ADIPOR2 Q86V24 Adiponectin receptor protein 2 chr12 GO:0042593 Not Cancer Driver No 31 0.0803108808290155 82 5 0.0129533678756476 0
ADISSP-202 ADISSP Q9GZN8 Adipose-secreted signaling protein chr20 GO:0042593 Not Cancer Driver No 20 0.1149425287356321 31 1 0.0057471264367816 0
ADRA2A-201 ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0042593 Not Cancer Driver No 46 0.0989247311827957 162 9 0.0193548387096774 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0042593 Census, Compendium Yes 99 0.20625 158 19 0.0395833333333333 4
ALOX5-201 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0042593 Not Cancer Driver No 100 0.1483679525222551 16 1 0.0014836795252225 0
APPL2-201 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0042593 Not Cancer Driver No 49 0.0737951807228915 149 8 0.0120481927710843 0
ASPSCR1-202 ASPSCR1 Q9BZE9 Tether containing UBX domain for GLUT4 chr17 GO:0042593 Census Yes 18 0.0325497287522604 298 11 0.0198915009041591 0
BACE2-202 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 GO:0042593 Not Cancer Driver No 47 0.0907335907335907 23 1 0.0019305019305019 0
BAD-201 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0042593 Not Cancer Driver No 10 0.0595238095238095 165 10 0.0595238095238095 0
BGLAP-201 BGLAP P02818 Osteocalcin chr1 GO:0042593 Not Cancer Driver No 6 0.06 21 0 0.0 0
BHLHA15-202 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0042593 Not Cancer Driver No 6 0.0317460317460317 183 6 0.0317460317460317 0
CAV3-201 CAV3 P56539 Caveolin-3 chr3 GO:0042593 Not Cancer Driver No 26 0.1721854304635761 0 0 0.0 24
CCN4-202 CCN4 O95388 CCN family member 4 chr8 GO:0042593 Not Cancer Driver No 84 0.2288828337874659 20 7 0.0190735694822888 0
CEBPA-201 CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0042593 Census, Compendium Yes 10 0.0279329608938547 343 10 0.0279329608938547 1
CMKLR2-208 CMKLR2 P46091 Chemerin-like receptor 2 chr2 GO:0042593 Not Cancer Driver No 36 0.1014084507042253 0 0 0.0 0
CNR1-203 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0042593 Not Cancer Driver No 102 0.2161016949152542 9 1 0.0021186440677966 0
CRTC2-203 CRTC2 Q53ET0 CREB-regulated transcription coactivator 2 chr1 GO:0042593 Not Cancer Driver No 73 0.1053391053391053 676 69 0.0995670995670995 0
CRY1-201 CRY1 Q16526 Cryptochrome-1 chr12 GO:0042593 Not Cancer Driver No 53 0.0904436860068259 91 3 0.0051194539249146 0
CRY2-211 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0042593 Not Cancer Driver No 54 0.0910623946037099 100 8 0.0134907251264755 0
CSMD1-217 CSMD1 Q96PZ7 CUB and sushi domain-containing protein 1 chr8 GO:0042593 Not Cancer Driver No 990 0.2777777777777778 234 63 0.0176767676767676 0
CSRP3-201 CSRP3 P50461 Cysteine and glycine-rich protein 3 chr11 GO:0042593 Not Cancer Driver No 23 0.1185567010309278 31 1 0.0051546391752577 2
CYB5R4-202 CYB5R4 Q7L1T6 Cytochrome b5 reductase 4 chr6 GO:0042593 Not Cancer Driver No 53 0.1017274472168906 56 7 0.0134357005758157 0
CYP11B1-201 CYP11B1 P15538 Cytochrome P450 11B1, mitochondrial chr8 GO:0042593 Not Cancer Driver No 154 0.3061630218687873 7 0 0.0 44
DBH-202 DBH P09172 Dopamine beta-hydroxylase chr9 GO:0042593 Not Cancer Driver No 102 0.1653160453808752 72 18 0.0291734197730956 3
DHPS-201 DHPS P49366 Deoxyhypusine synthase chr19 GO:0042593 Not Cancer Driver No 35 0.0948509485094851 70 2 0.005420054200542 1
DUSP29-201 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:0042593 Not Cancer Driver No 39 0.1772727272727272 55 7 0.0318181818181818 0
FABP5-201 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0042593 Not Cancer Driver No 11 0.0814814814814814 4 3 0.0222222222222222 0
FFAR1-201 FFAR1 O14842 Free fatty acid receptor 1 chr19 GO:0042593 Not Cancer Driver No 30 0.1 2 0 0.0 0
FFAR2-202 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0042593 Not Cancer Driver No 40 0.1212121212121212 32 7 0.0212121212121212 0
FGFR4-201 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0042593 Census, Compendium Yes 101 0.1259351620947631 163 27 0.0336658354114713 0
FOSL2-201 FOSL2 P15408 Fos-related antigen 2 chr2 GO:0042593 Not Cancer Driver No 39 0.1196319018404908 323 39 0.1196319018404908 0
FOXA1-201 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0042593 Census, Compendium Yes 85 0.1800847457627118 295 44 0.0932203389830508 0
G6PC1-201 G6PC1 P35575 Glucose-6-phosphatase catalytic subunit 1 chr17 GO:0042593 Not Cancer Driver No 38 0.1064425770308123 0 0 0.0 44
G6PC2-202 G6PC2 Q9NQR9 Glucose-6-phosphatase 2 chr2 GO:0042593 Not Cancer Driver No 44 0.1239436619718309 0 0 0.0 0
GCG-202 GCG P01275 Pro-glucagon chr2 GO:0042593 Not Cancer Driver No 40 0.2222222222222222 83 20 0.1111111111111111 0
GCGR-201 GCGR P47871 Glucagon receptor chr17 GO:0042593 Not Cancer Driver No 12 0.0251572327044025 56 2 0.0041928721174004 4
GCK-204 GCK P35557 Hexokinase-4 chr7 GO:0042593 Not Cancer Driver No 72 0.1548387096774193 73 12 0.0258064516129032 98
GCKR-201 GCKR Q14397 Glucokinase regulatory protein chr2 GO:0042593 Not Cancer Driver No 71 0.1136 85 22 0.0352 0
GPI-201 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0042593 Not Cancer Driver No 56 0.1003584229390681 73 10 0.017921146953405 23
GPR21-201 GPR21 Q99679 Probable G-protein coupled receptor 21 chr9 GO:0042593 Not Cancer Driver No 24 0.0687679083094555 2 0 0.0 0
HECTD4-216 HECTD4 Q9Y4D8 Probable E3 ubiquitin-protein ligase HECTD4 chr12 GO:0042593 Not Cancer Driver No 364 0.0823902218198279 1064 103 0.0233137166138524 0
HNF1A-201 HNF1A P20823 Hepatocyte nuclear factor 1-alpha chr12 GO:0042593 Census, Compendium Yes 83 0.1315372424722662 567 66 0.1045958795562599 38
HNF4A-201 HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 GO:0042593 Not Cancer Driver No 113 0.2383966244725738 127 44 0.0928270042194092 5
IGFBP5-201 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0042593 Not Cancer Driver No 23 0.0845588235294117 112 18 0.0661764705882353 0
IL6-201 IL6 P05231 Interleukin-6 chr7 GO:0042593 Not Cancer Driver No 32 0.1509433962264151 58 6 0.0283018867924528 0
INPP5K-204 INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0042593 Not Cancer Driver No 33 0.0736607142857142 34 2 0.0044642857142857 7
INS-202 INS P01308 Insulin chr11 GO:0042593 Not Cancer Driver No 7 0.0636363636363636 5 1 0.009090909090909 19
INSR-201 INSR P06213 Insulin receptor chr19 GO:0042593 Not Cancer Driver No 139 0.1005788712011577 282 37 0.0267727930535455 63
IRS1-201 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0042593 Not Cancer Driver No 118 0.0950080515297906 1075 104 0.0837359098228663 2
KCNB1-201 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0042593 Not Cancer Driver No 154 0.1794871794871795 417 82 0.0955710955710955 6
KLF7-201 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0042593 Not Cancer Driver No 36 0.119205298013245 72 4 0.0132450331125827 0
LEP-201 LEP P41159 Leptin chr7 GO:0042593 Not Cancer Driver No 20 0.1197604790419161 0 0 0.0 2
LEPR-202 LEPR P48357 Leptin receptor chr1 GO:0042593 Not Cancer Driver No 178 0.1527896995708154 57 10 0.0085836909871244 0
MBD5-201 MBD5 Q9P267 Methyl-CpG-binding domain protein 5 chr2 GO:0042593 Not Cancer Driver No 204 0.1365461847389558 1289 179 0.1198125836680053 0
MCU-202 MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0042593 Not Cancer Driver No 25 0.0712250712250712 13 0 0.0 0
MLXIPL-201 MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0042593 Not Cancer Driver No 86 0.1009389671361502 557 54 0.0633802816901408 0
MTNR1B-201 MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0042593 Not Cancer Driver No 80 0.2209944751381215 8 1 0.0027624309392265 0
NCOA5-201 NCOA5 Q9HCD5 Nuclear receptor coactivator 5 chr20 GO:0042593 Not Cancer Driver No 42 0.0725388601036269 482 31 0.0535405872193437 0
NEUROD1-201 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0042593 Not Cancer Driver No 68 0.1910112359550561 203 42 0.1179775280898876 2
NGFR-201 NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0042593 Not Cancer Driver No 46 0.1077283372365339 174 23 0.0538641686182669 0
OAS1-201 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0042593 Not Cancer Driver No 42 0.105 73 0 0.0 4
OBP2A-203 OBP2A Q9NY56 Odorant-binding protein 2a chr9 GO:0042593 Not Cancer Driver No 30 0.1764705882352941 22 1 0.0058823529411764 0
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0042593 Not Cancer Driver No 8 0.0423280423280423 30 0 0.0 6
PAX6-203 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0042593 Not Cancer Driver No 51 0.1208530805687203 338 37 0.0876777251184834 35
PCK1-201 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0042593 Not Cancer Driver No 112 0.180064308681672 111 24 0.0385852090032154 1
PDK2-203 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0042593 Not Cancer Driver No 32 0.0786240786240786 35 1 0.0024570024570024 0
PDK4-201 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0042593 Not Cancer Driver No 45 0.1094890510948905 14 1 0.0024330900243309 0
PFKM-203 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0042593 Not Cancer Driver No 56 0.0717948717948717 70 5 0.0064102564102564 8
PLSCR3-213 PLSCR3 Q9NRY6 Phospholipid scramblase 3 chr17 GO:0042593 Not Cancer Driver No 19 0.0644067796610169 62 3 0.0101694915254237 0
POMC-203 POMC P01189 Pro-opiomelanocortin chr2 GO:0042593 Not Cancer Driver No 28 0.1048689138576779 200 23 0.0861423220973782 0
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0042593 Census Yes 60 0.1188118811881188 44 3 0.0059405940594059 3
PPP1R3G-201 PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:0042593 Not Cancer Driver No 2 0.0055865921787709 198 1 0.0027932960893854 0
PRCP-201 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 GO:0042593 Not Cancer Driver No 40 0.0806451612903225 0 0 0.0 0
PRKAA1-204 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0042593 Not Cancer Driver No 54 0.0966010733452593 124 13 0.0232558139534883 0
PRKAA2-201 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0042593 Not Cancer Driver No 90 0.1630434782608695 98 18 0.0326086956521739 0
PTCH1-201 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0042593 Census, Compendium Yes 156 0.1078092605390463 383 39 0.0269523151347615 17
PTPN11-201 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0042593 Census, Compendium Yes 92 0.1551433389544688 260 27 0.0455311973018549 44
PTPN2-201 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0042593 Not Cancer Driver No 39 0.0939759036144578 120 10 0.0240963855421686 0
PYGL-201 PYGL P06737 Glycogen phosphorylase, liver form chr14 GO:0042593 Not Cancer Driver No 82 0.0968122786304604 23 1 0.0011806375442739 2
RBP4-201 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0042593 Not Cancer Driver No 25 0.1243781094527363 8 0 0.0 4
RFX6-201 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 GO:0042593 Not Cancer Driver No 188 0.2025862068965517 424 83 0.0894396551724138 3
RMI1-202 RMI1 Q9H9A7 RecQ-mediated genome instability protein 1 chr9 GO:0042593 Not Cancer Driver No 38 0.0608 243 16 0.0256 0
RPH3AL-202 RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0042593 Not Cancer Driver No 36 0.1142857142857142 162 17 0.0539682539682539 0
RPS6-204 RPS6 P62753 Small ribosomal subunit protein eS6 chr9 GO:0042593 Not Cancer Driver No 22 0.0883534136546184 150 15 0.0602409638554216 0
RRAGA-201 RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0042593 Not Cancer Driver No 22 0.0702875399361022 0 0 0.0 0
SELENOT-202 SELENOT P62341 Thioredoxin reductase-like selenoprotein T chr3 GO:0042593 Not Cancer Driver No 15 0.0769230769230769 0 0 0.0 0
SESN2-201 SESN2 P58004 Sestrin-2 chr1 GO:0042593 Not Cancer Driver No 54 0.1125 147 20 0.0416666666666666 0
SESN3-203 SESN3 P58005 Sestrin-3 chr11 GO:0042593 Not Cancer Driver No 58 0.1178861788617886 44 2 0.0040650406504065 0
SGCB-201 SGCB Q16585 Beta-sarcoglycan chr4 GO:0042593 Not Cancer Driver No 20 0.0628930817610062 80 5 0.0157232704402515 11
SIDT2-202 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 GO:0042593 Not Cancer Driver No 75 0.0901442307692307 23 3 0.0036057692307692 0
SIRT6-202 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0042593 Not Cancer Driver No 24 0.0676056338028169 165 6 0.0169014084507042 0
SLC16A1-201 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 GO:0042593 Not Cancer Driver No 52 0.104 70 4 0.008 3
SLC2A4-201 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0042593 Not Cancer Driver No 47 0.0923379174852652 44 6 0.0117878192534381 1
SLC30A8-202 SLC30A8 Q8IWU4 Proton-coupled zinc antiporter SLC30A8 chr8 GO:0042593 Not Cancer Driver No 95 0.2574525745257452 25 8 0.021680216802168 0
SLC8B1-217 SLC8B1 Q6J4K2 Mitochondrial sodium/calcium exchanger protein chr12 GO:0042593 Not Cancer Driver No 55 0.0941780821917808 0 0 0.0 0
SOX4-201 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0042593 Not Cancer Driver No 25 0.0527426160337552 402 20 0.0421940928270042 4
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0042593 Census, Compendium Yes 93 0.1207792207792207 152 16 0.0207792207792207 15
STK11-201 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0042593 Census, Compendium Yes 63 0.1454965357967667 135 12 0.0277136258660508 9
SUCNR1-201 SUCNR1 Q9BXA5 Succinate receptor 1 chr3 GO:0042593 Not Cancer Driver No 37 0.1107784431137724 0 0 0.0 0
TCF7L2-206 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0042593 Census, Compendium Yes 76 0.122778675282714 517 62 0.1001615508885298 0
TRPV4-201 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0042593 Not Cancer Driver No 109 0.1251435132032147 232 30 0.0344431687715269 38
TSC22D4-201 TSC22D4 Q9Y3Q8 TSC22 domain family protein 4 chr7 GO:0042593 Not Cancer Driver No 31 0.0784810126582278 364 28 0.070886075949367 0
USF1-203 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0042593 Not Cancer Driver No 28 0.0903225806451612 271 27 0.0870967741935483 0
VGF-201 VGF O15240 Neurosecretory protein VGF chr7 GO:0042593 Not Cancer Driver No 20 0.032520325203252 593 20 0.032520325203252 0
WFS1-201 WFS1 O76024 Wolframin chr4 GO:0042593 Not Cancer Driver No 78 0.0876404494382022 205 11 0.0123595505617977 40