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Total number of protein in "GO:0043124" GO term:  55

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADIPOQ-201 ADIPOQ Q15848 Adiponectin chr3 GO:0043124 Not Cancer Driver No 32 0.1311475409836065 92 16 0.0655737704918032 1
ARRB2-201 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0043124 Not Cancer Driver No 39 0.0953545232273838 122 19 0.0464547677261613 0
AZI2-212 AZI2 Q9H6S1 5-azacytidine-induced protein 2 chr3 GO:0043124 Not Cancer Driver No 24 0.0612244897959183 192 10 0.0255102040816326 0
CACTIN-203 CACTIN Q8WUQ7 Splicing factor Cactin chr19 GO:0043124 Not Cancer Driver No 51 0.0672823218997361 504 20 0.0263852242744063 0
CARD19-202 CARD19 Q96LW7 Caspase recruitment domain-containing protein 19 chr9 GO:0043124 Not Cancer Driver No 0 0.0 0 0 0.0 0
CARD8-231 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0043124 Not Cancer Driver No 41 0.0763500931098696 130 5 0.0093109869646182 1
CASP8-218 CASP8 Q14790 Caspase-8 chr2 GO:0043124 Census, Compendium Yes 116 0.2421711899791231 106 11 0.022964509394572 1
CCDC22-201 CCDC22 O60826 Coiled-coil domain-containing protein 22 chrX GO:0043124 Not Cancer Driver No 42 0.0669856459330143 243 8 0.0127591706539074 2
DAB2IP-203 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0043124 Not Cancer Driver No 95 0.0798990748528175 682 49 0.04121110176619 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 GO:0043124 Census, Compendium Yes 92 0.1546218487394958 198 19 0.0319327731092436 2
GSTP1-202 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0043124 Not Cancer Driver No 23 0.1095238095238095 0 0 0.0 0
HDAC1-201 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0043124 Not Cancer Driver No 30 0.0622406639004149 135 5 0.0103734439834024 0
IRGM-202 IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0043124 Not Cancer Driver No 7 0.0386740331491712 51 0 0.0 0
LILRB4-211 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0043124 Not Cancer Driver No 122 0.2723214285714285 276 88 0.1964285714285714 0
MAPKBP1-201 MAPKBP1 O60336 Mitogen-activated protein kinase-binding protein 1 chr15 GO:0043124 Not Cancer Driver No 128 0.0845442536327609 786 58 0.0383091149273447 0
NFKBIA-201 NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0043124 Compendium Yes 34 0.1072555205047318 102 10 0.0315457413249211 1
NFKBIL1-203 NFKBIL1 Q9UBC1 NF-kappa-B inhibitor-like protein 1 chr6 GO:0043124 Not Cancer Driver No 30 0.0787401574803149 316 26 0.0682414698162729 0
NKIRAS1-206 NKIRAS1 Q9NYS0 NF-kappa-B inhibitor-interacting Ras-like protein 1 chr3 GO:0043124 Not Cancer Driver No 11 0.0572916666666666 21 0 0.0 0
NKIRAS2-206 NKIRAS2 Q9NYR9 NF-kappa-B inhibitor-interacting Ras-like protein 2 chr17 GO:0043124 Not Cancer Driver No 20 0.1047120418848167 27 2 0.0104712041884816 0
NLRC3-202 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0043124 Not Cancer Driver No 136 0.1276995305164319 150 29 0.0272300469483568 0
NLRP12-201 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0043124 Not Cancer Driver No 258 0.2431668237511781 115 37 0.0348727615457115 0
NLRP6-201 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0043124 Not Cancer Driver No 68 0.0762331838565022 205 11 0.0123318385650224 0
NLRX1-202 NLRX1 Q86UT6 NLR family member X1 chr11 GO:0043124 Not Cancer Driver No 105 0.1076923076923077 95 11 0.0112820512820512 0
NR1D1-201 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0043124 Not Cancer Driver No 56 0.0912052117263843 348 39 0.0635179153094462 0
NR1H4-209 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0043124 Not Cancer Driver No 82 0.1687242798353909 78 13 0.0267489711934156 0
OPTN-202 OPTN Q96CV9 Optineurin chr10 GO:0043124 Not Cancer Driver No 47 0.0814558058925476 475 40 0.0693240901213171 6
OTUD7B-202 OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 GO:0043124 Not Cancer Driver No 99 0.1174377224199288 538 72 0.0854092526690391 0
PER1-201 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0043124 Census Yes 128 0.0992248062015503 950 98 0.075968992248062 0
PPM1A-203 PPM1A P35813 Protein phosphatase 1A chr14 GO:0043124 Not Cancer Driver No 36 0.094240837696335 134 15 0.0392670157068062 0
PPM1B-201 PPM1B O75688 Protein phosphatase 1B chr2 GO:0043124 Not Cancer Driver No 53 0.1106471816283924 243 26 0.0542797494780793 0
PPM1N-207 PPM1N Q8N819 Probable protein phosphatase 1N chr19 GO:0043124 Not Cancer Driver No 20 0.0465116279069767 152 6 0.013953488372093 0
PYCARD-201 PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0043124 Not Cancer Driver No 12 0.0615384615384615 39 4 0.0205128205128205 0
RHOH-201 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 GO:0043124 Census Yes 32 0.1675392670157068 12 3 0.0157068062827225 0
RIOK3-201 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0043124 Not Cancer Driver No 39 0.0751445086705202 225 15 0.0289017341040462 0
RIPK1-201 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0043124 Compendium Yes 59 0.0879284649776453 277 28 0.0417287630402384 1
RORA-203 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0043124 Not Cancer Driver No 43 0.0822179732313575 181 11 0.0210325047801147 4
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0043124 Not Cancer Driver No 43 0.0575635876840696 435 19 0.0254350736278447 0
SLC39A8-201 SLC39A8 Q9C0K1 Metal cation symporter ZIP8 chr4 GO:0043124 Not Cancer Driver No 30 0.0652173913043478 22 2 0.0043478260869565 6
SNIP1-201 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 GO:0043124 Not Cancer Driver No 45 0.1136363636363636 286 32 0.0808080808080808 1
STAT1-201 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0043124 Not Cancer Driver No 100 0.1333333333333333 144 16 0.0213333333333333 23
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0043124 Not Cancer Driver No 37 0.0870588235294117 302 25 0.0588235294117647 0
TGFBR3-201 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0043124 Not Cancer Driver No 104 0.1222091656874265 268 36 0.0423031727379553 0
TLE1-203 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 GO:0043124 Not Cancer Driver No 86 0.1116883116883116 385 39 0.0506493506493506 0
TMSB4X-204 TMSB4X P62328 Thymosin beta-4 chrX GO:0043124 Census Yes 7 0.1590909090909091 45 7 0.1590909090909091 0
TNFAIP3-206 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0043124 Census, Compendium Yes 69 0.0873417721518987 231 21 0.0265822784810126 1
TNIP1-211 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0043124 Not Cancer Driver No 62 0.0974842767295597 628 60 0.0943396226415094 0
TNIP3-201 TNIP3 Q96KP6 TNFAIP3-interacting protein 3 chr4 GO:0043124 Not Cancer Driver No 59 0.1815384615384615 250 40 0.123076923076923 0
TREM2-202 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0043124 Not Cancer Driver No 31 0.1347826086956521 27 2 0.008695652173913 1
TRIM39-201 TRIM39 Q9HCM9 E3 ubiquitin-protein ligase TRIM39 chr6 GO:0043124 Not Cancer Driver No 67 0.1293436293436293 62 7 0.0135135135135135 0
TRIM59-201 TRIM59 Q8IWR1 Tripartite motif-containing protein 59 chr3 GO:0043124 Not Cancer Driver No 32 0.0794044665012407 33 4 0.009925558312655 0
TSPAN6-201 TSPAN6 O43657 Tetraspanin-6 chrX GO:0043124 Not Cancer Driver No 26 0.1061224489795918 0 0 0.0 0
USP10-201 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 GO:0043124 Not Cancer Driver No 65 0.081453634085213 423 34 0.0426065162907268 0
USP20-203 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 GO:0043124 Not Cancer Driver No 87 0.0951859956236323 296 30 0.0328227571115973 0
ZC3H12A-201 ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0043124 Not Cancer Driver No 77 0.1285475792988314 397 38 0.0634390651085141 0
ZMYND11-203 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:0043124 Not Cancer Driver No 49 0.0813953488372093 184 19 0.0315614617940199 0