Total number of protein in "GO:0043154" GO term: 38
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0043154 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AQP1-201 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0043154 | Not Cancer Driver | No | 30 | 0.1115241635687732 | 4 | 0 | 0.0 | 0 |
| ARL6IP1-201 | ARL6IP1 | Q15041 | ADP-ribosylation factor-like protein 6-interacting protein 1 | chr16 | GO:0043154 | Not Cancer Driver | No | 23 | 0.1133004926108374 | 9 | 0 | 0.0 | 0 |
| AVP-201 | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0043154 | Not Cancer Driver | No | 11 | 0.0670731707317073 | 26 | 1 | 0.0060975609756097 | 26 |
| CARD16-204 | CARD16 | Q5EG05 | Caspase recruitment domain-containing protein 16 | chr11 | GO:0043154 | Not Cancer Driver | No | 26 | 0.1319796954314721 | 23 | 5 | 0.0253807106598984 | 0 |
| CD44-208 | CD44 | P16070 | CD44 antigen | chr11 | GO:0043154 | Not Cancer Driver | No | 58 | 0.0781671159029649 | 547 | 50 | 0.0673854447439353 | 0 |
| CDKN2D-202 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:0043154 | Not Cancer Driver | No | 17 | 0.1024096385542168 | 45 | 3 | 0.0180722891566265 | 0 |
| CSNK2A1-201 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0043154 | Not Cancer Driver | No | 47 | 0.1202046035805626 | 75 | 6 | 0.0153452685421994 | 4 |
| DDX3X-244 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0043154 | Census, Compendium | Yes | 91 | 0.1374622356495468 | 302 | 32 | 0.0483383685800604 | 18 |
| DNAJB6-201 | DNAJB6 | O75190 | DnaJ homolog subfamily B member 6 | chr7 | GO:0043154 | Not Cancer Driver | No | 4 | 0.0122699386503067 | 198 | 2 | 0.0061349693251533 | 3 |
| DPEP1-210 | DPEP1 | P16444 | Dipeptidase 1 | chr16 | GO:0043154 | Not Cancer Driver | No | 42 | 0.1021897810218978 | 41 | 7 | 0.0170316301703163 | 0 |
| FABP1-201 | FABP1 | P07148 | Fatty acid-binding protein, liver | chr2 | GO:0043154 | Not Cancer Driver | No | 23 | 0.1811023622047244 | 0 | 0 | 0.0 | 0 |
| FNIP1-203 | FNIP1 | Q8TF40 | Folliculin-interacting protein 1 | chr5 | GO:0043154 | Not Cancer Driver | No | 94 | 0.0806174957118353 | 386 | 30 | 0.0257289879931389 | 0 |
| GAS6-201 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0043154 | Not Cancer Driver | No | 60 | 0.0884955752212389 | 43 | 3 | 0.0044247787610619 | 0 |
| GPX1-202 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0043154 | Not Cancer Driver | No | 22 | 0.1083743842364532 | 12 | 3 | 0.0147783251231527 | 0 |
| IFI6-202 | IFI6 | P09912 | Interferon alpha-inducible protein 6 | chr1 | GO:0043154 | Not Cancer Driver | No | 9 | 0.0692307692307692 | 7 | 0 | 0.0 | 0 |
| IGBP1-202 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | GO:0043154 | Not Cancer Driver | No | 32 | 0.0943952802359882 | 194 | 18 | 0.0530973451327433 | 0 |
| KLF4-201 | KLF4 | O43474 | Krueppel-like factor 4 | chr9 | GO:0043154 | Census, Compendium | Yes | 41 | 0.0855949895615866 | 417 | 25 | 0.0521920668058455 | 0 |
| LAMP3-201 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | GO:0043154 | Not Cancer Driver | No | 57 | 0.1370192307692307 | 223 | 34 | 0.0817307692307692 | 0 |
| LAMTOR5-206 | LAMTOR5 | O43504 | Ragulator complex protein LAMTOR5 | chr1 | GO:0043154 | Not Cancer Driver | No | 8 | 0.0879120879120879 | 17 | 0 | 0.0 | 0 |
| MAGEA3-201 | MAGEA3 | P43357 | Melanoma-associated antigen 3 | chrX | GO:0043154 | Not Cancer Driver | No | 74 | 0.2356687898089172 | 104 | 16 | 0.0509554140127388 | 0 |
| MAP2K5-201 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | GO:0043154 | Not Cancer Driver | No | 26 | 0.0580357142857142 | 85 | 6 | 0.0133928571428571 | 0 |
| NAIP-208 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0043154 | Not Cancer Driver | No | 29 | 0.0206699928724162 | 67 | 4 | 0.0028510334996436 | 0 |
| PAX2-205 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0043154 | Not Cancer Driver | No | 49 | 0.1175059952038369 | 294 | 39 | 0.0935251798561151 | 22 |
| RAF1-201 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | GO:0043154 | Census, Compendium | Yes | 64 | 0.0987654320987654 | 169 | 30 | 0.0462962962962962 | 18 |
| RPS6KA1-204 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | GO:0043154 | Not Cancer Driver | No | 71 | 0.0965986394557823 | 178 | 22 | 0.0299319727891156 | 0 |
| RPS6KA3-201 | RPS6KA3 | P51812 | Ribosomal protein S6 kinase alpha-3 | chrX | GO:0043154 | Compendium | Yes | 72 | 0.0972972972972973 | 146 | 10 | 0.0135135135135135 | 13 |
| SFN-201 | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0043154 | Not Cancer Driver | No | 16 | 0.064516129032258 | 75 | 3 | 0.0120967741935483 | 0 |
| SH3RF1-201 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0043154 | Not Cancer Driver | No | 83 | 0.0934684684684684 | 588 | 55 | 0.0619369369369369 | 0 |
| SIAH2-201 | SIAH2 | O43255 | E3 ubiquitin-protein ligase SIAH2 | chr3 | GO:0043154 | Not Cancer Driver | No | 34 | 0.1049382716049382 | 68 | 2 | 0.0061728395061728 | 0 |
| SNCA-205 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0043154 | Not Cancer Driver | No | 15 | 0.1071428571428571 | 107 | 10 | 0.0714285714285714 | 5 |
| SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0043154 | Census | Yes | 40 | 0.0746268656716417 | 130 | 10 | 0.0186567164179104 | 1 |
| THBS1-201 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0043154 | Not Cancer Driver | No | 153 | 0.1307692307692307 | 321 | 50 | 0.0427350427350427 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0043154 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TRIAP1-202 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0043154 | Not Cancer Driver | No | 8 | 0.1052631578947368 | 20 | 1 | 0.0131578947368421 | 0 |
| USP47-203 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0043154 | Not Cancer Driver | No | 86 | 0.0625454545454545 | 426 | 24 | 0.0174545454545454 | 0 |
| VEGFA-226 | VEGFA | P15692 | Vascular endothelial growth factor A, long form | chr6 | GO:0043154 | Not Cancer Driver | No | 24 | 0.060759493670886 | 215 | 9 | 0.0227848101265822 | 0 |
| XIAP-202 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0043154 | Not Cancer Driver | No | 61 | 0.1227364185110664 | 55 | 2 | 0.0040241448692152 | 0 |