Total number of protein in "GO:0043536" GO term: 38
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM17-201 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0043536 | Not Cancer Driver | No | 63 | 0.0764563106796116 | 182 | 17 | 0.020631067961165 | 0 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0043536 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AKT3-217 | AKT3 | Q9Y243 | RAC-gamma serine/threonine-protein kinase | chr1 | GO:0043536 | Census, Compendium | Yes | 71 | 0.1482254697286012 | 131 | 19 | 0.0396659707724425 | 3 |
| ANGPT1-202 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0043536 | Not Cancer Driver | No | 100 | 0.2008032128514056 | 131 | 10 | 0.0200803212851405 | 1 |
| ANGPT4-201 | ANGPT4 | Q9Y264 | Angiopoietin-4 | chr20 | GO:0043536 | Not Cancer Driver | No | 87 | 0.172962226640159 | 152 | 31 | 0.0616302186878727 | 0 |
| ATP5F1A-202 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | GO:0043536 | Not Cancer Driver | No | 48 | 0.0867992766726944 | 23 | 3 | 0.0054249547920434 | 2 |
| ATP5F1B-201 | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | GO:0043536 | Not Cancer Driver | No | 46 | 0.0869565217391304 | 85 | 7 | 0.0132325141776937 | 1 |
| CD40-202 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0043536 | Not Cancer Driver | No | 32 | 0.1155234657039711 | 57 | 6 | 0.0216606498194945 | 2 |
| ETS1-201 | ETS1 | P14921 | Protein C-ets-1 | chr11 | GO:0043536 | Not Cancer Driver | No | 47 | 0.1065759637188208 | 78 | 6 | 0.0136054421768707 | 0 |
| FGF18-201 | FGF18 | O76093 | Fibroblast growth factor 18 | chr5 | GO:0043536 | Not Cancer Driver | No | 29 | 0.1400966183574879 | 57 | 8 | 0.038647342995169 | 0 |
| FGF2-201 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0043536 | Not Cancer Driver | No | 17 | 0.0590277777777777 | 183 | 5 | 0.0173611111111111 | 0 |
| FGFR1-214 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0043536 | Census, Compendium | Yes | 92 | 0.1119221411192214 | 231 | 26 | 0.0316301703163017 | 69 |
| GATA2-201 | GATA2 | P23769 | Endothelial transcription factor GATA-2 | chr3 | GO:0043536 | Census, Compendium | Yes | 60 | 0.125 | 372 | 43 | 0.0895833333333333 | 6 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0043536 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HMGB1-203 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0043536 | Not Cancer Driver | No | 10 | 0.0465116279069767 | 202 | 7 | 0.0325581395348837 | 0 |
| HSPB1-201 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0043536 | Not Cancer Driver | No | 10 | 0.048780487804878 | 118 | 8 | 0.0390243902439024 | 19 |
| KDR-201 | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0043536 | Census, Compendium | Yes | 276 | 0.2035398230088495 | 276 | 40 | 0.0294985250737463 | 2 |
| MAP2K3-202 | MAP2K3 | P46734 | Dual specificity mitogen-activated protein kinase kinase 3 | chr17 | GO:0043536 | Not Cancer Driver | No | 74 | 0.2132564841498559 | 76 | 19 | 0.0547550432276657 | 0 |
| MAPK14-201 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0043536 | Not Cancer Driver | No | 22 | 0.0611111111111111 | 25 | 0 | 0.0 | 0 |
| NFE2L2-201 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0043536 | Census, Compendium | Yes | 235 | 0.3884297520661157 | 402 | 59 | 0.0975206611570247 | 4 |
| NOS3-201 | NOS3 | P29474 | Nitric oxide synthase 3 | chr7 | GO:0043536 | Not Cancer Driver | No | 143 | 0.1188694929343308 | 349 | 30 | 0.0249376558603491 | 0 |
| NUS1-201 | NUS1 | Q96E22 | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | chr6 | GO:0043536 | Not Cancer Driver | No | 12 | 0.0409556313993174 | 14 | 0 | 0.0 | 2 |
| P2RX4-202 | P2RX4 | Q99571 | P2X purinoceptor 4 | chr12 | GO:0043536 | Not Cancer Driver | No | 20 | 0.0515463917525773 | 0 | 0 | 0.0 | 0 |
| PDGFB-201 | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0043536 | Census | Yes | 30 | 0.1244813278008298 | 99 | 16 | 0.0663900414937759 | 2 |
| PDPK1-202 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0043536 | Not Cancer Driver | No | 23 | 0.0413669064748201 | 121 | 9 | 0.0161870503597122 | 0 |
| PLCG1-202 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0043536 | Census, Compendium | Yes | 129 | 0.1 | 187 | 15 | 0.0116279069767441 | 0 |
| PLG-202 | PLG | P00747 | Plasminogen | chr6 | GO:0043536 | Not Cancer Driver | No | 190 | 0.2345679012345679 | 233 | 55 | 0.0679012345679012 | 9 |
| PRKCA-202 | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0043536 | Not Cancer Driver | No | 70 | 0.1041666666666666 | 155 | 17 | 0.025297619047619 | 0 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0043536 | Census | Yes | 164 | 0.1798245614035087 | 190 | 31 | 0.0339912280701754 | 2 |
| PRKD2-201 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0043536 | Compendium | Yes | 89 | 0.1013667425968109 | 247 | 26 | 0.0296127562642369 | 0 |
| SIRT1-201 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0043536 | Not Cancer Driver | No | 43 | 0.0575635876840696 | 435 | 19 | 0.0254350736278447 | 0 |
| SP1-201 | SP1 | P08047 | Transcription factor Sp1 | chr12 | GO:0043536 | Not Cancer Driver | No | 67 | 0.0853503184713375 | 601 | 53 | 0.0675159235668789 | 0 |
| STAT5A-209 | STAT5A | P42229 | Signal transducer and activator of transcription 5A | chr17 | GO:0043536 | Not Cancer Driver | No | 64 | 0.0806045340050377 | 125 | 7 | 0.008816120906801 | 0 |
| TGFB1-201 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0043536 | Not Cancer Driver | No | 30 | 0.0769230769230769 | 44 | 3 | 0.0076923076923076 | 8 |
| THBS1-201 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0043536 | Not Cancer Driver | No | 153 | 0.1307692307692307 | 321 | 50 | 0.0427350427350427 | 0 |
| TMSB4X-204 | TMSB4X | P62328 | Thymosin beta-4 | chrX | GO:0043536 | Census | Yes | 7 | 0.1590909090909091 | 45 | 7 | 0.1590909090909091 | 0 |
| VEGFA-226 | VEGFA | P15692 | Vascular endothelial growth factor A, long form | chr6 | GO:0043536 | Not Cancer Driver | No | 24 | 0.060759493670886 | 215 | 9 | 0.0227848101265822 | 0 |
| VEGFC-202 | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0043536 | Not Cancer Driver | No | 104 | 0.2482100238663484 | 37 | 8 | 0.0190930787589498 | 0 |