Total number of protein in "GO:0045444" GO term: 81
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGRF1-203 | ADGRF1 | Q5T601 | Adhesion G-protein coupled receptor F1 | chr6 | GO:0045444 | Not Cancer Driver | No | 122 | 0.134065934065934 | 8 | 0 | 0.0 | 0 |
| ADGRF5-202 | ADGRF5 | Q8IZF2 | Adhesion G protein-coupled receptor F5 | chr6 | GO:0045444 | Not Cancer Driver | No | 180 | 0.1337295690936107 | 53 | 7 | 0.0052005943536404 | 0 |
| AKT2-206 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0045444 | Census | Yes | 57 | 0.1185031185031185 | 84 | 9 | 0.0187110187110187 | 2 |
| ALOXE3-203 | ALOXE3 | Q9BYJ1 | Hydroperoxide isomerase ALOXE3 | chr17 | GO:0045444 | Not Cancer Driver | No | 80 | 0.1125175808720112 | 69 | 10 | 0.0140646976090014 | 6 |
| ANGPTL8-201 | ANGPTL8 | Q6UXH0 | Angiopoietin-like protein 8 | chr19 | GO:0045444 | Not Cancer Driver | No | 18 | 0.0909090909090909 | 26 | 8 | 0.0404040404040404 | 0 |
| ARID5B-201 | ARID5B | Q14865 | AT-rich interactive domain-containing protein 5B | chr10 | GO:0045444 | Not Cancer Driver | No | 133 | 0.1119528619528619 | 770 | 82 | 0.069023569023569 | 0 |
| ATF5-201 | ATF5 | Q9Y2D1 | Cyclic AMP-dependent transcription factor ATF-5 | chr19 | GO:0045444 | Not Cancer Driver | No | 31 | 0.1099290780141844 | 242 | 27 | 0.0957446808510638 | 0 |
| BBS1-201 | BBS1 | Q8NFJ9 | Bardet-Biedl syndrome 1 protein | chr11 | GO:0045444 | Not Cancer Driver | No | 52 | 0.087689713322091 | 100 | 9 | 0.0151770657672849 | 11 |
| BBS12-201 | BBS12 | Q6ZW61 | Bardet-Biedl syndrome 12 protein | chr4 | GO:0045444 | Not Cancer Driver | No | 60 | 0.0845070422535211 | 34 | 2 | 0.0028169014084507 | 10 |
| BBS2-201 | BBS2 | Q9BXC9 | Bardet-Biedl syndrome 2 protein | chr16 | GO:0045444 | Not Cancer Driver | No | 60 | 0.0832177531206657 | 76 | 8 | 0.0110957004160887 | 20 |
| BBS4-201 | BBS4 | Q96RK4 | Bardet-Biedl syndrome 4 protein | chr15 | GO:0045444 | Not Cancer Driver | No | 44 | 0.0847784200385356 | 111 | 14 | 0.0269749518304431 | 9 |
| BBS7-201 | BBS7 | Q8IWZ6 | Bardet-Biedl syndrome 7 protein | chr4 | GO:0045444 | Not Cancer Driver | No | 69 | 0.0965034965034965 | 56 | 4 | 0.0055944055944055 | 4 |
| BBS9-201 | BBS9 | Q3SYG4 | Protein PTHB1 | chr7 | GO:0045444 | Not Cancer Driver | No | 128 | 0.1443066516347237 | 103 | 16 | 0.0180383314543404 | 1 |
| BSCL2-207 | BSCL2 | Q96G97 | Seipin | chr11 | GO:0045444 | Not Cancer Driver | No | 37 | 0.092964824120603 | 126 | 7 | 0.0175879396984924 | 5 |
| C1QTNF3-201 | C1QTNF3 | Q9BXJ4 | Complement C1q tumor necrosis factor-related protein 3 | chr5 | GO:0045444 | Not Cancer Driver | No | 33 | 0.1341463414634146 | 73 | 12 | 0.048780487804878 | 0 |
| CBY1-201 | CBY1 | Q9Y3M2 | Protein chibby homolog 1 | chr22 | GO:0045444 | Not Cancer Driver | No | 9 | 0.0714285714285714 | 98 | 7 | 0.0555555555555555 | 0 |
| CCND1-201 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0045444 | Census, Compendium | Yes | 47 | 0.159322033898305 | 32 | 25 | 0.0847457627118644 | 0 |
| CEBPA-201 | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0045444 | Census, Compendium | Yes | 10 | 0.0279329608938547 | 343 | 10 | 0.0279329608938547 | 1 |
| CEBPD-201 | CEBPD | P49716 | CCAAT/enhancer-binding protein delta | chr8 | GO:0045444 | Not Cancer Driver | No | 5 | 0.0185873605947955 | 234 | 4 | 0.0148698884758364 | 0 |
| CLIP3-201 | CLIP3 | Q96DZ5 | CAP-Gly domain-containing linker protein 3 | chr19 | GO:0045444 | Not Cancer Driver | No | 55 | 0.1005484460694698 | 220 | 15 | 0.0274223034734917 | 0 |
| CNTN2-201 | CNTN2 | Q02246 | Contactin-2 | chr1 | GO:0045444 | Not Cancer Driver | No | 130 | 0.125 | 371 | 56 | 0.0538461538461538 | 0 |
| EGR2-201 | EGR2 | P11161 | E3 SUMO-protein ligase EGR2 | chr10 | GO:0045444 | Compendium | Yes | 58 | 0.1218487394957983 | 352 | 38 | 0.0798319327731092 | 10 |
| ENST00000419755 | BBS1 | Q8NFJ9 | Bardet-Biedl syndrome 1 protein | chr11 | GO:0045444 | Not Cancer Driver | No | 52 | 0.0825396825396825 | 132 | 7 | 0.0111111111111111 | 11 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0045444 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| ERAP1-202 | ERAP1 | Q9NZ08 | Endoplasmic reticulum aminopeptidase 1 | chr5 | GO:0045444 | Not Cancer Driver | No | 57 | 0.0605738575982996 | 70 | 1 | 0.0010626992561105 | 0 |
| FAM120B-201 | FAM120B | Q96EK7 | Constitutive coactivator of peroxisome proliferator-activated receptor gamma | chr6 | GO:0045444 | Not Cancer Driver | No | 75 | 0.0824175824175824 | 296 | 22 | 0.0241758241758241 | 0 |
| FBXO9-201 | FBXO9 | Q9UK97 | F-box only protein 9 | chr6 | GO:0045444 | Not Cancer Driver | No | 34 | 0.076062639821029 | 110 | 7 | 0.0156599552572706 | 0 |
| FFAR2-202 | FFAR2 | O15552 | Free fatty acid receptor 2 | chr19 | GO:0045444 | Not Cancer Driver | No | 40 | 0.1212121212121212 | 32 | 7 | 0.0212121212121212 | 0 |
| FOSL2-201 | FOSL2 | P15408 | Fos-related antigen 2 | chr2 | GO:0045444 | Not Cancer Driver | No | 39 | 0.1196319018404908 | 323 | 39 | 0.1196319018404908 | 0 |
| FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0045444 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
| GATA2-201 | GATA2 | P23769 | Endothelial transcription factor GATA-2 | chr3 | GO:0045444 | Census, Compendium | Yes | 60 | 0.125 | 372 | 43 | 0.0895833333333333 | 6 |
| GDF10-201 | GDF10 | P55107 | Growth/differentiation factor 10 | chr10 | GO:0045444 | Not Cancer Driver | No | 81 | 0.1694560669456067 | 254 | 54 | 0.1129707112970711 | 0 |
| GDF6-201 | GDF6 | Q6KF10 | Growth/differentiation factor 6 | chr8 | GO:0045444 | Not Cancer Driver | No | 73 | 0.1604395604395604 | 225 | 38 | 0.0835164835164835 | 14 |
| GPX1-202 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0045444 | Not Cancer Driver | No | 22 | 0.1083743842364532 | 12 | 3 | 0.0147783251231527 | 0 |
| GRK5-202 | GRK5 | P34947 | G protein-coupled receptor kinase 5 | chr10 | GO:0045444 | Not Cancer Driver | No | 58 | 0.0983050847457627 | 105 | 12 | 0.0203389830508474 | 0 |
| HMGA2-204 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:0045444 | Census | Yes | 9 | 0.0825688073394495 | 109 | 9 | 0.0825688073394495 | 0 |
| ID4-201 | ID4 | P47928 | DNA-binding protein inhibitor ID-4 | chr6 | GO:0045444 | Not Cancer Driver | No | 5 | 0.031055900621118 | 72 | 1 | 0.0062111801242236 | 0 |
| IL11-201 | IL11 | P20809 | Interleukin-11 | chr19 | GO:0045444 | Not Cancer Driver | No | 10 | 0.050251256281407 | 70 | 4 | 0.0201005025125628 | 0 |
| INHBB-201 | INHBB | P09529 | Inhibin beta B chain | chr2 | GO:0045444 | Not Cancer Driver | No | 40 | 0.0982800982800982 | 98 | 2 | 0.0049140049140049 | 0 |
| JDP2-208 | JDP2 | Q8WYK2 | Jun dimerization protein 2 | chr14 | GO:0045444 | Not Cancer Driver | No | 16 | 0.0981595092024539 | 142 | 13 | 0.0797546012269938 | 0 |
| KCNJ8-201 | KCNJ8 | Q15842 | ATP-sensitive inward rectifier potassium channel 8 | chr12 | GO:0045444 | Not Cancer Driver | No | 78 | 0.1839622641509433 | 69 | 17 | 0.0400943396226415 | 1 |
| KLF4-201 | KLF4 | O43474 | Krueppel-like factor 4 | chr9 | GO:0045444 | Census, Compendium | Yes | 41 | 0.0855949895615866 | 417 | 25 | 0.0521920668058455 | 0 |
| LRRC8C-201 | LRRC8C | Q8TDW0 | Volume-regulated anion channel subunit LRRC8C | chr1 | GO:0045444 | Not Cancer Driver | No | 68 | 0.0846824408468244 | 59 | 5 | 0.0062266500622665 | 0 |
| MAFB-201 | MAFB | Q9Y5Q3 | Transcription factor MafB | chr20 | GO:0045444 | Census | Yes | 29 | 0.0897832817337461 | 301 | 28 | 0.0866873065015479 | 8 |
| MED1-201 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0045444 | Not Cancer Driver | No | 81 | 0.0512333965844402 | 1104 | 50 | 0.0316255534471853 | 0 |
| METRNL-201 | METRNL | Q641Q3 | Meteorin-like protein | chr17 | GO:0045444 | Not Cancer Driver | No | 22 | 0.0707395498392283 | 88 | 5 | 0.0160771704180064 | 0 |
| MKKS-201 | MKKS | Q9NPJ1 | Molecular chaperone MKKS | chr20 | GO:0045444 | Not Cancer Driver | No | 35 | 0.0614035087719298 | 7 | 0 | 0.0 | 22 |
| NIPBL-201 | NIPBL | Q6KC79 | Nipped-B-like protein | chr5 | GO:0045444 | Compendium | Yes | 262 | 0.0934379457917261 | 1530 | 138 | 0.0492154065620542 | 35 |
| NOC3L-201 | NOC3L | Q8WTT2 | Nucleolar complex protein 3 homolog | chr10 | GO:0045444 | Not Cancer Driver | No | 49 | 0.06125 | 284 | 21 | 0.02625 | 0 |
| NR4A1-204 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | GO:0045444 | Not Cancer Driver | No | 52 | 0.0869565217391304 | 252 | 24 | 0.040133779264214 | 0 |
| NR4A2-201 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0045444 | Not Cancer Driver | No | 84 | 0.1404682274247491 | 262 | 32 | 0.0535117056856187 | 3 |
| NR4A3-203 | NR4A3 | Q92570 | Nuclear receptor subfamily 4 group A member 3 | chr9 | GO:0045444 | Census | Yes | 52 | 0.0830670926517571 | 298 | 29 | 0.0463258785942492 | 0 |
| OSBPL11-201 | OSBPL11 | Q9BXB4 | Oxysterol-binding protein-related protein 11 | chr3 | GO:0045444 | Not Cancer Driver | No | 45 | 0.0602409638554216 | 336 | 22 | 0.0294511378848728 | 0 |
| OSBPL8-201 | OSBPL8 | Q9BZF1 | Oxysterol-binding protein-related protein 8 | chr12 | GO:0045444 | Not Cancer Driver | No | 79 | 0.0888638920134983 | 402 | 31 | 0.0348706411698537 | 0 |
| PIAS1-201 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | GO:0045444 | Not Cancer Driver | No | 48 | 0.0737327188940092 | 241 | 25 | 0.0384024577572964 | 0 |
| PID1-201 | PID1 | Q7Z2X4 | PTB-containing, cubilin and LRP1-interacting protein | chr2 | GO:0045444 | Not Cancer Driver | No | 61 | 0.244 | 24 | 9 | 0.036 | 0 |
| PLCB1-201 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0045444 | Not Cancer Driver | No | 264 | 0.2171052631578947 | 484 | 85 | 0.0699013157894736 | 0 |
| PRLH-201 | PRLH | P81277 | Prolactin-releasing peptide | chr2 | GO:0045444 | Not Cancer Driver | No | 7 | 0.0804597701149425 | 28 | 3 | 0.0344827586206896 | 0 |
| PSMB8-202 | PSMB8 | P28062 | Proteasome subunit beta type-8 | chr6 | GO:0045444 | Not Cancer Driver | No | 34 | 0.1231884057971014 | 62 | 6 | 0.0217391304347826 | 3 |
| RETN-201 | RETN | Q9HD89 | Resistin | chr19 | GO:0045444 | Not Cancer Driver | No | 9 | 0.0833333333333333 | 0 | 0 | 0.0 | 0 |
| RNASEL-201 | RNASEL | Q05823 | 2-5A-dependent ribonuclease | chr1 | GO:0045444 | Not Cancer Driver | No | 66 | 0.0890688259109311 | 149 | 14 | 0.0188933873144399 | 0 |
| SDF4-202 | SDF4 | Q9BRK5 | 45 kDa calcium-binding protein | chr1 | GO:0045444 | Not Cancer Driver | No | 38 | 0.1070422535211267 | 195 | 27 | 0.076056338028169 | 0 |
| SENP2-201 | SENP2 | Q9HC62 | Sentrin-specific protease 2 | chr3 | GO:0045444 | Not Cancer Driver | No | 41 | 0.0696095076400679 | 285 | 22 | 0.0373514431239388 | 0 |
| SMAD6-201 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0045444 | Not Cancer Driver | No | 29 | 0.0584677419354838 | 249 | 4 | 0.0080645161290322 | 7 |
| SOCS1-201 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | GO:0045444 | Census, Compendium | Yes | 20 | 0.0947867298578199 | 66 | 3 | 0.0142180094786729 | 2 |
| SOX8-201 | SOX8 | P57073 | Transcription factor SOX-8 | chr16 | GO:0045444 | Not Cancer Driver | No | 38 | 0.085201793721973 | 403 | 35 | 0.0784753363228699 | 0 |
| SREBF1-201 | SREBF1 | P36956 | Sterol regulatory element-binding protein 1 | chr17 | GO:0045444 | Not Cancer Driver | No | 87 | 0.075850043591979 | 530 | 42 | 0.036617262423714 | 3 |
| STEAP4-202 | STEAP4 | Q687X5 | Metalloreductase STEAP4 | chr7 | GO:0045444 | Not Cancer Driver | No | 72 | 0.1568627450980392 | 0 | 0 | 0.0 | 0 |
| TCF7L2-206 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0045444 | Census, Compendium | Yes | 76 | 0.122778675282714 | 517 | 62 | 0.1001615508885298 | 0 |
| TFAP2B-202 | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0045444 | Not Cancer Driver | No | 77 | 0.1673913043478261 | 306 | 55 | 0.1195652173913043 | 5 |
| TGFB1I1-203 | TGFB1I1 | O43294 | Transforming growth factor beta-1-induced transcript 1 protein | chr16 | GO:0045444 | Not Cancer Driver | No | 49 | 0.106290672451193 | 219 | 27 | 0.0585683297180043 | 0 |
| TMEM120A-214 | TMEM120A | Q9BXJ8 | Ion channel TACAN | chr7 | GO:0045444 | Not Cancer Driver | No | 0 | 0.0 | 27 | 0 | 0.0 | 0 |
| TMEM120B-204 | TMEM120B | A0PK00 | Transmembrane protein 120B | chr12 | GO:0045444 | Not Cancer Driver | No | 24 | 0.0707964601769911 | 6 | 1 | 0.0029498525073746 | 0 |
| TRIM32-203 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0045444 | Not Cancer Driver | No | 62 | 0.0949464012251148 | 87 | 9 | 0.0137825421133231 | 3 |
| TTC8-201 | TTC8 | Q8TAM2 | Tetratricopeptide repeat protein 8 | chr14 | GO:0045444 | Not Cancer Driver | No | 54 | 0.1016949152542373 | 78 | 11 | 0.0207156308851224 | 0 |
| WNT1-201 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0045444 | Not Cancer Driver | No | 20 | 0.054054054054054 | 25 | 0 | 0.0 | 8 |
| WNT10B-201 | WNT10B | O00744 | Protein Wnt-10b | chr12 | GO:0045444 | Not Cancer Driver | No | 45 | 0.1156812339331619 | 84 | 14 | 0.0359897172236503 | 2 |
| WNT3A-201 | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0045444 | Not Cancer Driver | No | 60 | 0.1704545454545454 | 37 | 2 | 0.0056818181818181 | 0 |
| WNT5B-202 | WNT5B | Q9H1J7 | Protein Wnt-5b | chr12 | GO:0045444 | Not Cancer Driver | No | 55 | 0.1532033426183844 | 23 | 4 | 0.011142061281337 | 0 |
| ZBTB7A-201 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | GO:0045444 | Not Cancer Driver | No | 50 | 0.0856164383561643 | 286 | 26 | 0.0445205479452054 | 2 |
| ZFPM2-201 | ZFPM2 | Q8WW38 | Zinc finger protein ZFPM2 | chr8 | GO:0045444 | Not Cancer Driver | No | 310 | 0.2693310165073849 | 660 | 195 | 0.1694178974804517 | 8 |