Total number of protein in "GO:0045454" GO term: 41
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0045454 | Not Cancer Driver | No | 23 | 0.0723270440251572 | 104 | 9 | 0.0283018867924528 | 0 |
| BOLA1-202 | BOLA1 | Q9Y3E2 | BolA-like protein 1 | chr1 | GO:0045454 | Not Cancer Driver | No | 24 | 0.1751824817518248 | 71 | 10 | 0.072992700729927 | 0 |
| BOLA2-201 | BOLA2B | Q9H3K6 | BolA-like protein 2 | chr16 | GO:0045454 | Not Cancer Driver | No | 0 | 0.0 | 16 | 0 | 0.0 | 0 |
| BOLA2B-205 | BOLA2B | Q9H3K6 | BolA-like protein 2 | chr16 | GO:0045454 | Not Cancer Driver | No | 0 | 0.0 | 16 | 0 | 0.0 | 0 |
| BOLA3-202 | BOLA3 | Q53S33 | BolA-like protein 3 | chr2 | GO:0045454 | Not Cancer Driver | No | 7 | 0.0654205607476635 | 27 | 0 | 0.0 | 2 |
| CHD6-202 | CHD6 | Q8TD26 | Chromodomain-helicase-DNA-binding protein 6 | chr20 | GO:0045454 | Not Cancer Driver | No | 294 | 0.1082872928176795 | 1474 | 164 | 0.0604051565377532 | 0 |
| DDIT3-201 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0045454 | Census | Yes | 19 | 0.1124260355029585 | 161 | 17 | 0.1005917159763313 | 0 |
| EGLN2-201 | EGLN2 | Q96KS0 | Prolyl hydroxylase EGLN2 | chr19 | GO:0045454 | Not Cancer Driver | No | 36 | 0.0884520884520884 | 204 | 9 | 0.0221130221130221 | 0 |
| ERO1A-201 | ERO1A | Q96HE7 | ERO1-like protein alpha | chr14 | GO:0045454 | Not Cancer Driver | No | 34 | 0.0726495726495726 | 33 | 4 | 0.0085470085470085 | 0 |
| ERP44-201 | ERP44 | Q9BS26 | Endoplasmic reticulum resident protein 44 | chr9 | GO:0045454 | Not Cancer Driver | No | 33 | 0.0812807881773399 | 43 | 3 | 0.0073891625615763 | 0 |
| GCLC-214 | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0045454 | Not Cancer Driver | No | 55 | 0.086342229199372 | 167 | 15 | 0.0235478806907378 | 3 |
| GIT1-201 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | GO:0045454 | Not Cancer Driver | No | 48 | 0.0630749014454664 | 434 | 26 | 0.0341655716162943 | 0 |
| GLRX2-201 | GLRX2 | Q9NS18 | Glutaredoxin-2, mitochondrial | chr1 | GO:0045454 | Not Cancer Driver | No | 9 | 0.0548780487804878 | 10 | 2 | 0.0121951219512195 | 0 |
| GLRX3-201 | GLRX3 | O76003 | Glutaredoxin-3 | chr10 | GO:0045454 | Not Cancer Driver | No | 32 | 0.0955223880597015 | 24 | 1 | 0.0029850746268656 | 0 |
| GLRX5-201 | GLRX5 | Q86SX6 | Glutaredoxin-related protein 5, mitochondrial | chr14 | GO:0045454 | Not Cancer Driver | No | 5 | 0.0318471337579617 | 23 | 0 | 0.0 | 2 |
| GPX1-202 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0045454 | Not Cancer Driver | No | 22 | 0.1083743842364532 | 12 | 3 | 0.0147783251231527 | 0 |
| GSR-201 | GSR | P00390 | Glutathione reductase, mitochondrial | chr8 | GO:0045454 | Not Cancer Driver | No | 37 | 0.0708812260536398 | 55 | 4 | 0.0076628352490421 | 1 |
| HVCN1-201 | HVCN1 | Q96D96 | Voltage-gated hydrogen channel 1 | chr12 | GO:0045454 | Not Cancer Driver | No | 46 | 0.1684981684981685 | 52 | 14 | 0.0512820512820512 | 0 |
| KRIT1-203 | KRIT1 | O00522 | Krev interaction trapped protein 1 | chr7 | GO:0045454 | Not Cancer Driver | No | 65 | 0.0883152173913043 | 113 | 16 | 0.0217391304347826 | 2 |
| NFE2L2-201 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0045454 | Census, Compendium | Yes | 235 | 0.3884297520661157 | 402 | 59 | 0.0975206611570247 | 4 |
| NNT-202 | NNT | Q13423 | NAD(P) transhydrogenase, mitochondrial | chr5 | GO:0045454 | Not Cancer Driver | No | 96 | 0.0883977900552486 | 47 | 5 | 0.0046040515653775 | 11 |
| NOS1-201 | NOS1 | P29475 | Nitric oxide synthase 1 | chr12 | GO:0045454 | Not Cancer Driver | No | 329 | 0.2294281729428172 | 342 | 84 | 0.0585774058577405 | 0 |
| NOS2-201 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0045454 | Not Cancer Driver | No | 147 | 0.1274934952298352 | 201 | 26 | 0.0225498699045967 | 0 |
| NOS3-201 | NOS3 | P29474 | Nitric oxide synthase 3 | chr7 | GO:0045454 | Not Cancer Driver | No | 143 | 0.1188694929343308 | 349 | 30 | 0.0249376558603491 | 0 |
| NQO1-201 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | GO:0045454 | Not Cancer Driver | No | 11 | 0.0401459854014598 | 10 | 0 | 0.0 | 0 |
| PRDX1-202 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | GO:0045454 | Not Cancer Driver | No | 23 | 0.1155778894472361 | 40 | 7 | 0.0351758793969849 | 0 |
| PRDX2-201 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | GO:0045454 | Not Cancer Driver | No | 22 | 0.1111111111111111 | 30 | 3 | 0.0151515151515151 | 0 |
| PRDX3-201 | PRDX3 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | chr10 | GO:0045454 | Not Cancer Driver | No | 17 | 0.06640625 | 23 | 2 | 0.0078125 | 2 |
| PRDX4-202 | PRDX4 | Q13162 | Peroxiredoxin-4 | chrX | GO:0045454 | Not Cancer Driver | No | 31 | 0.1143911439114391 | 29 | 2 | 0.007380073800738 | 0 |
| PRDX5-201 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | GO:0045454 | Not Cancer Driver | No | 13 | 0.0607476635514018 | 0 | 0 | 0.0 | 0 |
| PRDX6-201 | PRDX6 | P30041 | Peroxiredoxin-6 | chr1 | GO:0045454 | Not Cancer Driver | No | 32 | 0.1428571428571428 | 13 | 3 | 0.0133928571428571 | 0 |
| SELENOS-203 | SELENOS | Q9BQE4 | Selenoprotein S | chr15 | GO:0045454 | Not Cancer Driver | No | 4 | 0.0211640211640211 | 123 | 3 | 0.0158730158730158 | 0 |
| SELENOT-202 | SELENOT | P62341 | Thioredoxin reductase-like selenoprotein T | chr3 | GO:0045454 | Not Cancer Driver | No | 15 | 0.0769230769230769 | 0 | 0 | 0.0 | 0 |
| SLC11A1-201 | SLC11A1 | P49279 | Natural resistance-associated macrophage protein 1 | chr2 | GO:0045454 | Not Cancer Driver | No | 62 | 0.1127272727272727 | 47 | 5 | 0.009090909090909 | 0 |
| SLC2A10-201 | SLC2A10 | O95528 | Solute carrier family 2, facilitated glucose transporter member 10 | chr20 | GO:0045454 | Not Cancer Driver | No | 79 | 0.1460258780036968 | 72 | 10 | 0.0184842883548983 | 8 |
| TXN-202 | TXN | P10599 | Thioredoxin | chr9 | GO:0045454 | Not Cancer Driver | No | 5 | 0.0476190476190476 | 0 | 0 | 0.0 | 0 |
| TXN2-201 | TXN2 | Q99757 | Thioredoxin, mitochondrial | chr22 | GO:0045454 | Not Cancer Driver | No | 15 | 0.0903614457831325 | 34 | 4 | 0.0240963855421686 | 0 |
| TXNDC2-201 | TXNDC2 | Q86VQ3 | Thioredoxin domain-containing protein 2 | chr18 | GO:0045454 | Not Cancer Driver | No | 76 | 0.1374321880650994 | 453 | 60 | 0.1084990958408679 | 0 |
| TXNRD1-204 | TXNRD1 | Q16881 | Thioredoxin reductase 1, cytoplasmic | chr12 | GO:0045454 | Not Cancer Driver | No | 59 | 0.0909090909090909 | 67 | 8 | 0.012326656394453 | 0 |
| TXNRD2-204 | TXNRD2 | Q9NNW7 | Thioredoxin reductase 2, mitochondrial | chr22 | GO:0045454 | Not Cancer Driver | No | 51 | 0.0973282442748091 | 47 | 4 | 0.0076335877862595 | 0 |
| TXNRD3-204 | TXNRD3 | Q86VQ6 | Thioredoxin reductase 3 | chr3 | GO:0045454 | Not Cancer Driver | No | 1 | 0.0015552099533437 | 66 | 0 | 0.0 | 0 |