Total number of protein in "GO:0045471" GO term: 100
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABAT-201 | ABAT | P80404 | 4-aminobutyrate aminotransferase, mitochondrial | chr16 | GO:0045471 | Not Cancer Driver | No | 69 | 0.138 | 28 | 6 | 0.012 | 1 |
| ABCB11-206 | ABCB11 | O95342 | Bile salt export pump | chr2 | GO:0045471 | Not Cancer Driver | No | 167 | 0.1264193792581378 | 125 | 20 | 0.0151400454201362 | 21 |
| ADCYAP1R1-201 | ADCYAP1R1 | P41586 | Pituitary adenylate cyclase-activating polypeptide type I receptor | chr7 | GO:0045471 | Not Cancer Driver | No | 108 | 0.2307692307692307 | 0 | 0 | 0.0 | 0 |
| ADH6-201 | ADH6 | P28332 | Alcohol dehydrogenase 6 | chr4 | GO:0045471 | Not Cancer Driver | No | 46 | 0.125 | 0 | 0 | 0.0 | 0 |
| ADH7-201 | ADH7 | P40394 | All-trans-retinol dehydrogenase [NAD(+)] ADH7 | chr4 | GO:0045471 | Not Cancer Driver | No | 59 | 0.1528497409326424 | 15 | 1 | 0.0025906735751295 | 0 |
| ADIPOQ-201 | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0045471 | Not Cancer Driver | No | 32 | 0.1311475409836065 | 92 | 16 | 0.0655737704918032 | 1 |
| ALAD-201 | ALAD | P13716 | Delta-aminolevulinic acid dehydratase | chr9 | GO:0045471 | Not Cancer Driver | No | 35 | 0.106060606060606 | 13 | 2 | 0.006060606060606 | 5 |
| ATP5F1A-202 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | GO:0045471 | Not Cancer Driver | No | 48 | 0.0867992766726944 | 23 | 3 | 0.0054249547920434 | 2 |
| AVP-201 | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0045471 | Not Cancer Driver | No | 11 | 0.0670731707317073 | 26 | 1 | 0.0060975609756097 | 26 |
| BAK1-201 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0045471 | Not Cancer Driver | No | 25 | 0.1184834123222748 | 58 | 5 | 0.0236966824644549 | 0 |
| BGLAP-201 | BGLAP | P02818 | Osteocalcin | chr1 | GO:0045471 | Not Cancer Driver | No | 6 | 0.06 | 21 | 0 | 0.0 | 0 |
| BIRC2-201 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0045471 | Not Cancer Driver | No | 49 | 0.0792880258899676 | 85 | 7 | 0.0113268608414239 | 0 |
| CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0045471 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
| CAT-201 | CAT | P04040 | Catalase | chr11 | GO:0045471 | Not Cancer Driver | No | 56 | 0.1062618595825427 | 178 | 11 | 0.0208728652751423 | 0 |
| CBL-201 | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0045471 | Census, Compendium | Yes | 84 | 0.0927152317880794 | 513 | 44 | 0.0485651214128035 | 4 |
| CD14-201 | CD14 | P08571 | Monocyte differentiation antigen CD14 | chr5 | GO:0045471 | Not Cancer Driver | No | 34 | 0.0906666666666666 | 60 | 5 | 0.0133333333333333 | 0 |
| CD27-201 | CD27 | P26842 | CD27 antigen | chr12 | GO:0045471 | Not Cancer Driver | No | 24 | 0.0923076923076923 | 92 | 10 | 0.0384615384615384 | 1 |
| CDK1-203 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0045471 | Not Cancer Driver | No | 26 | 0.0875420875420875 | 1 | 0 | 0.0 | 0 |
| CDO1-201 | CDO1 | Q16878 | Cysteine dioxygenase type 1 | chr5 | GO:0045471 | Not Cancer Driver | No | 24 | 0.12 | 43 | 1 | 0.005 | 0 |
| CHRNB2-201 | CHRNB2 | P17787 | Neuronal acetylcholine receptor subunit beta-2 | chr1 | GO:0045471 | Not Cancer Driver | No | 72 | 0.1434262948207171 | 23 | 1 | 0.0019920318725099 | 1 |
| CLDN1-201 | CLDN1 | O95832 | Claudin-1 | chr3 | GO:0045471 | Not Cancer Driver | No | 19 | 0.0900473933649289 | 16 | 0 | 0.0 | 0 |
| CLDN18-201 | CLDN18 | P56856 | Claudin-18 | chr3 | GO:0045471 | Not Cancer Driver | No | 28 | 0.10727969348659 | 21 | 2 | 0.0076628352490421 | 0 |
| CLDN3-201 | CLDN3 | O15551 | Claudin-3 | chr7 | GO:0045471 | Not Cancer Driver | No | 12 | 0.0545454545454545 | 0 | 0 | 0.0 | 0 |
| CLDN5-204 | CLDN5 | O00501 | Claudin-5 | chr22 | GO:0045471 | Not Cancer Driver | No | 17 | 0.0779816513761468 | 0 | 0 | 0.0 | 0 |
| CLDN7-201 | CLDN7 | O95471 | Claudin-7 | chr17 | GO:0045471 | Not Cancer Driver | No | 8 | 0.0379146919431279 | 2 | 0 | 0.0 | 0 |
| CNR1-203 | CNR1 | P21554 | Cannabinoid receptor 1 | chr6 | GO:0045471 | Not Cancer Driver | No | 102 | 0.2161016949152542 | 9 | 1 | 0.0021186440677966 | 0 |
| CPT1A-201 | CPT1A | P50416 | Carnitine O-palmitoyltransferase 1, liver isoform | chr11 | GO:0045471 | Not Cancer Driver | No | 115 | 0.148771021992238 | 65 | 10 | 0.0129366106080207 | 15 |
| CRH-201 | CRH | P06850 | Corticoliberin | chr8 | GO:0045471 | Not Cancer Driver | No | 9 | 0.0459183673469387 | 131 | 9 | 0.0459183673469387 | 0 |
| CSF3-201 | CSF3 | P09919 | Granulocyte colony-stimulating factor | chr17 | GO:0045471 | Not Cancer Driver | No | 16 | 0.0772946859903381 | 7 | 0 | 0.0 | 0 |
| CTSK-201 | CTSK | P43235 | Cathepsin K | chr1 | GO:0045471 | Not Cancer Driver | No | 32 | 0.0972644376899696 | 24 | 3 | 0.0091185410334346 | 6 |
| CYP7A1-201 | CYP7A1 | P22680 | Cytochrome P450 7A1 | chr8 | GO:0045471 | Not Cancer Driver | No | 71 | 0.1408730158730158 | 48 | 4 | 0.0079365079365079 | 0 |
| DMAP1-203 | DMAP1 | Q9NPF5 | DNA methyltransferase 1-associated protein 1 | chr1 | GO:0045471 | Not Cancer Driver | No | 42 | 0.0899357601713062 | 270 | 26 | 0.0556745182012847 | 0 |
| DRD3-202 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0045471 | Not Cancer Driver | No | 67 | 0.1675 | 45 | 15 | 0.0375 | 0 |
| EHMT2-203 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | GO:0045471 | Not Cancer Driver | No | 103 | 0.0851239669421487 | 585 | 49 | 0.040495867768595 | 0 |
| EIF4G1-202 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | GO:0045471 | Not Cancer Driver | No | 157 | 0.0981863664790494 | 1080 | 103 | 0.0644152595372107 | 2 |
| FECH-201 | FECH | P22830 | Ferrochelatase, mitochondrial | chr18 | GO:0045471 | Not Cancer Driver | No | 39 | 0.0921985815602836 | 57 | 5 | 0.0118203309692671 | 22 |
| FGFR2-206 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0045471 | Census, Compendium | Yes | 193 | 0.2350791717417783 | 229 | 34 | 0.0414129110840438 | 57 |
| FOS-201 | FOS | P01100 | Protein c-Fos | chr14 | GO:0045471 | Not Cancer Driver | No | 37 | 0.0973684210526315 | 247 | 28 | 0.0736842105263157 | 0 |
| FYN-202 | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0045471 | Not Cancer Driver | No | 64 | 0.1191806331471136 | 71 | 11 | 0.0204841713221601 | 0 |
| G6PD-202 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | GO:0045471 | Not Cancer Driver | No | 64 | 0.1242718446601941 | 28 | 3 | 0.0058252427184466 | 51 |
| GABBR1-204 | GABBR1 | Q9UBS5 | Gamma-aminobutyric acid type B receptor subunit 1 | chr6 | GO:0045471 | Not Cancer Driver | No | 117 | 0.1217481789802289 | 142 | 16 | 0.0166493236212278 | 0 |
| GNRH1-202 | GNRH1 | P01148 | Progonadoliberin-1 | chr8 | GO:0045471 | Not Cancer Driver | No | 16 | 0.1739130434782608 | 29 | 6 | 0.0652173913043478 | 0 |
| GOT2-201 | GOT2 | P00505 | Aspartate aminotransferase, mitochondrial | chr16 | GO:0045471 | Not Cancer Driver | No | 45 | 0.1046511627906976 | 25 | 3 | 0.0069767441860465 | 1 |
| GRIN1-208 | GRIN1 | Q05586 | Glutamate receptor ionotropic, NMDA 1 | chr9 | GO:0045471 | Not Cancer Driver | No | 71 | 0.0756929637526652 | 190 | 8 | 0.0085287846481876 | 12 |
| GRIN2A-201 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0045471 | Census, Compendium | Yes | 439 | 0.2998633879781421 | 507 | 172 | 0.1174863387978142 | 32 |
| GRIN2B-201 | GRIN2B | Q13224 | Glutamate receptor ionotropic, NMDA 2B | chr12 | GO:0045471 | Not Cancer Driver | No | 331 | 0.2230458221024258 | 428 | 116 | 0.0781671159029649 | 12 |
| GRIN3A-201 | GRIN3A | Q8TCU5 | Glutamate receptor ionotropic, NMDA 3A | chr9 | GO:0045471 | Not Cancer Driver | No | 252 | 0.2260089686098654 | 183 | 19 | 0.0170403587443946 | 0 |
| HMGCS2-201 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0045471 | Not Cancer Driver | No | 65 | 0.1279527559055118 | 29 | 2 | 0.0039370078740157 | 19 |
| HPGD-202 | HPGD | P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | chr4 | GO:0045471 | Not Cancer Driver | No | 19 | 0.0714285714285714 | 4 | 1 | 0.0037593984962406 | 2 |
| HTR1B-201 | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | GO:0045471 | Not Cancer Driver | No | 72 | 0.1846153846153846 | 33 | 13 | 0.0333333333333333 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0045471 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| IL13-201 | IL13 | P35225 | Interleukin-13 | chr5 | GO:0045471 | Not Cancer Driver | No | 12 | 0.0821917808219178 | 0 | 0 | 0.0 | 0 |
| IL2-201 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0045471 | Census | Yes | 16 | 0.1045751633986928 | 6 | 0 | 0.0 | 0 |
| KCNC2-208 | KCNC2 | Q96PR1 | Potassium voltage-gated channel subfamily C member 2 | chr12 | GO:0045471 | Not Cancer Driver | No | 131 | 0.2053291536050156 | 255 | 49 | 0.0768025078369906 | 8 |
| LEP-201 | LEP | P41159 | Leptin | chr7 | GO:0045471 | Not Cancer Driver | No | 20 | 0.1197604790419161 | 0 | 0 | 0.0 | 2 |
| MAOB-201 | MAOB | P27338 | Amine oxidase [flavin-containing] B | chrX | GO:0045471 | Not Cancer Driver | No | 65 | 0.125 | 44 | 6 | 0.0115384615384615 | 0 |
| MSTN-201 | MSTN | O14793 | Growth/differentiation factor 8 | chr2 | GO:0045471 | Not Cancer Driver | No | 54 | 0.144 | 65 | 11 | 0.0293333333333333 | 0 |
| MT-CYB-201 | MT-CYB | P00156 | Cytochrome b | chrM | GO:0045471 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
| MT-ND4-201 | MT-ND4 | P03905 | NADH-ubiquinone oxidoreductase chain 4 | chrM | GO:0045471 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 3 |
| MYD88-209 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0045471 | Census, Compendium | Yes | 29 | 0.0979729729729729 | 47 | 2 | 0.0067567567567567 | 2 |
| NPPC-202 | NPPC | P23582 | C-type natriuretic peptide | chr2 | GO:0045471 | Not Cancer Driver | No | 8 | 0.0634920634920634 | 82 | 5 | 0.0396825396825396 | 0 |
| NQO1-201 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | GO:0045471 | Not Cancer Driver | No | 11 | 0.0401459854014598 | 10 | 0 | 0.0 | 0 |
| NR0B2-201 | NR0B2 | Q15466 | Nuclear receptor subfamily 0 group B member 2 | chr1 | GO:0045471 | Not Cancer Driver | No | 30 | 0.1167315175097276 | 10 | 2 | 0.0077821011673151 | 0 |
| OGG1-205 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0045471 | Not Cancer Driver | No | 26 | 0.0753623188405797 | 72 | 4 | 0.0115942028985507 | 0 |
| OPRK1-201 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0045471 | Not Cancer Driver | No | 97 | 0.2552631578947368 | 18 | 5 | 0.0131578947368421 | 0 |
| PAX6-203 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0045471 | Not Cancer Driver | No | 51 | 0.1208530805687203 | 338 | 37 | 0.0876777251184834 | 35 |
| PENK-202 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0045471 | Not Cancer Driver | No | 92 | 0.3445692883895131 | 143 | 55 | 0.2059925093632958 | 0 |
| POLB-201 | POLB | P06746 | DNA polymerase beta | chr8 | GO:0045471 | Not Cancer Driver | No | 32 | 0.0955223880597015 | 87 | 8 | 0.0238805970149253 | 0 |
| PPARA-202 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | GO:0045471 | Not Cancer Driver | No | 49 | 0.1047008547008547 | 68 | 9 | 0.0192307692307692 | 0 |
| PRKCB-201 | PRKCB | P05771 | Protein kinase C beta type | chr16 | GO:0045471 | Census, Compendium | Yes | 153 | 0.2280178837555886 | 148 | 26 | 0.0387481371087928 | 0 |
| PSMD14-201 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | GO:0045471 | Not Cancer Driver | No | 14 | 0.0451612903225806 | 68 | 3 | 0.0096774193548387 | 0 |
| PTH-201 | PTH | P01270 | Parathyroid hormone | chr11 | GO:0045471 | Not Cancer Driver | No | 17 | 0.1478260869565217 | 61 | 10 | 0.0869565217391304 | 2 |
| PTK2B-201 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0045471 | Not Cancer Driver | No | 117 | 0.1159563924677899 | 263 | 23 | 0.0227948463825569 | 0 |
| RARA-201 | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0045471 | Census, Compendium | Yes | 60 | 0.1298701298701298 | 167 | 14 | 0.0303030303030303 | 0 |
| RGS19-202 | RGS19 | P49795 | Regulator of G-protein signaling 19 | chr20 | GO:0045471 | Not Cancer Driver | No | 19 | 0.0875576036866359 | 71 | 6 | 0.0276497695852534 | 0 |
| RGS2-201 | RGS2 | P41220 | Regulator of G-protein signaling 2 | chr1 | GO:0045471 | Not Cancer Driver | No | 18 | 0.0853080568720379 | 50 | 2 | 0.0094786729857819 | 0 |
| RGS4-203 | RGS4 | P49798 | Regulator of G-protein signaling 4 | chr1 | GO:0045471 | Not Cancer Driver | No | 46 | 0.224390243902439 | 5 | 3 | 0.0146341463414634 | 0 |
| RGS7-205 | RGS7 | P49802 | Regulator of G-protein signaling 7 | chr1 | GO:0045471 | Census, Compendium | Yes | 169 | 0.3414141414141414 | 150 | 43 | 0.0868686868686868 | 0 |
| RPL15-201 | RPL15 | P61313 | Large ribosomal subunit protein eL15 | chr3 | GO:0045471 | Not Cancer Driver | No | 13 | 0.0637254901960784 | 84 | 7 | 0.034313725490196 | 0 |
| RPS6KB1-201 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0045471 | Not Cancer Driver | No | 36 | 0.0685714285714285 | 226 | 22 | 0.0419047619047619 | 0 |
| S100A8-202 | S100A8 | P05109 | Protein S100-A8 | chr1 | GO:0045471 | Not Cancer Driver | No | 17 | 0.1827956989247312 | 8 | 4 | 0.043010752688172 | 0 |
| SDF4-202 | SDF4 | Q9BRK5 | 45 kDa calcium-binding protein | chr1 | GO:0045471 | Not Cancer Driver | No | 38 | 0.1070422535211267 | 195 | 27 | 0.076056338028169 | 0 |
| SETD7-201 | SETD7 | Q8WTS6 | Histone-lysine N-methyltransferase SETD7 | chr4 | GO:0045471 | Not Cancer Driver | No | 26 | 0.0710382513661202 | 106 | 5 | 0.0136612021857923 | 0 |
| SLC10A1-201 | SLC10A1 | Q14973 | Hepatic sodium/bile acid cotransporter | chr14 | GO:0045471 | Not Cancer Driver | No | 32 | 0.0916905444126074 | 0 | 0 | 0.0 | 5 |
| SLC2A4-201 | SLC2A4 | P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | chr17 | GO:0045471 | Not Cancer Driver | No | 47 | 0.0923379174852652 | 44 | 6 | 0.0117878192534381 | 1 |
| SLC6A3-201 | SLC6A3 | Q01959 | Sodium-dependent dopamine transporter | chr5 | GO:0045471 | Not Cancer Driver | No | 131 | 0.2112903225806451 | 31 | 5 | 0.0080645161290322 | 2 |
| SOD1-201 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | GO:0045471 | Not Cancer Driver | No | 14 | 0.0909090909090909 | 94 | 9 | 0.0584415584415584 | 57 |
| SPINK1-201 | SPINK1 | P00995 | Serine protease inhibitor Kazal-type 1 | chr5 | GO:0045471 | Not Cancer Driver | No | 10 | 0.1265822784810126 | 0 | 0 | 0.0 | 3 |
| SREBF1-201 | SREBF1 | P36956 | Sterol regulatory element-binding protein 1 | chr17 | GO:0045471 | Not Cancer Driver | No | 87 | 0.075850043591979 | 530 | 42 | 0.036617262423714 | 3 |
| ST6GAL1-201 | ST6GAL1 | P15907 | Beta-galactoside alpha-2,6-sialyltransferase 1 | chr3 | GO:0045471 | Not Cancer Driver | No | 39 | 0.0960591133004926 | 34 | 6 | 0.0147783251231527 | 0 |
| TACR1-201 | TACR1 | P25103 | Substance-P receptor | chr2 | GO:0045471 | Not Cancer Driver | No | 55 | 0.1351351351351351 | 28 | 2 | 0.0049140049140049 | 0 |
| TBXA2R-201 | TBXA2R | P21731 | Thromboxane A2 receptor | chr19 | GO:0045471 | Not Cancer Driver | No | 42 | 0.1224489795918367 | 17 | 3 | 0.0087463556851311 | 1 |
| TBXAS1-207 | TBXAS1 | P24557 | Thromboxane-A synthase | chr7 | GO:0045471 | Not Cancer Driver | No | 92 | 0.1726078799249531 | 45 | 5 | 0.0093808630393996 | 4 |
| TH-206 | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0045471 | Not Cancer Driver | No | 48 | 0.0909090909090909 | 151 | 17 | 0.0321969696969696 | 38 |
| TNC-202 | TNC | P24821 | Tenascin | chr9 | GO:0045471 | Census, Compendium | Yes | 241 | 0.1094956837800999 | 575 | 78 | 0.0354384370740572 | 2 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0045471 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFRSF11A-202 | TNFRSF11A | Q9Y6Q6 | Tumor necrosis factor receptor superfamily member 11A | chr18 | GO:0045471 | Not Cancer Driver | No | 61 | 0.099025974025974 | 286 | 33 | 0.0535714285714285 | 5 |
| TUFM-201 | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | GO:0045471 | Not Cancer Driver | No | 36 | 0.0791208791208791 | 51 | 4 | 0.0087912087912087 | 1 |
| TYMS-203 | TYMS | P04818 | Thymidylate synthase | chr18 | GO:0045471 | Not Cancer Driver | No | 18 | 0.0575079872204472 | 41 | 0 | 0.0 | 0 |
| VCAM1-201 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | GO:0045471 | Not Cancer Driver | No | 152 | 0.2056833558863328 | 110 | 21 | 0.0284167794316644 | 0 |