Total number of protein in "GO:0045597" GO term: 60
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTB-217 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:0045597 | Not Cancer Driver | No | 96 | 0.256 | 43 | 5 | 0.0133333333333333 | 4 |
| ACTL6A-202 | ACTL6A | O96019 | Actin-like protein 6A | chr3 | GO:0045597 | Not Cancer Driver | No | 39 | 0.0909090909090909 | 74 | 8 | 0.0186480186480186 | 1 |
| ACTL6B-201 | ACTL6B | O94805 | Actin-like protein 6B | chr7 | GO:0045597 | Not Cancer Driver | No | 64 | 0.1502347417840375 | 108 | 13 | 0.0305164319248826 | 3 |
| AR-201 | AR | P10275 | Androgen receptor | chrX | GO:0045597 | Census, Compendium | Yes | 116 | 0.1260869565217391 | 443 | 38 | 0.0413043478260869 | 144 |
| ARID1A-201 | ARID1A | O14497 | AT-rich interactive domain-containing protein 1A | chr1 | GO:0045597 | Census, Compendium | Yes | 204 | 0.0892778993435448 | 1857 | 142 | 0.062144420131291 | 0 |
| ARID1B-203 | ARID1B | Q8NFD5 | AT-rich interactive domain-containing protein 1B | chr6 | GO:0045597 | Census, Compendium | Yes | 202 | 0.0871065114273393 | 1891 | 150 | 0.0646830530401035 | 2 |
| ARID2-201 | ARID2 | Q68CP9 | AT-rich interactive domain-containing protein 2 | chr12 | GO:0045597 | Census, Compendium | Yes | 205 | 0.1117166212534059 | 1144 | 111 | 0.0604904632152588 | 0 |
| BRD7-201 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | GO:0045597 | Compendium | Yes | 58 | 0.0890937019969278 | 485 | 33 | 0.0506912442396313 | 0 |
| BTC-201 | BTC | P35070 | Probetacellulin | chr4 | GO:0045597 | Not Cancer Driver | No | 23 | 0.1292134831460674 | 12 | 5 | 0.0280898876404494 | 0 |
| CCN1-201 | CCN1 | O00622 | CCN family member 1 | chr1 | GO:0045597 | Not Cancer Driver | No | 29 | 0.0761154855643044 | 12 | 0 | 0.0 | 0 |
| CCN2-201 | CCN2 | P29279 | CCN family member 2 | chr6 | GO:0045597 | Not Cancer Driver | No | 37 | 0.1060171919770773 | 0 | 0 | 0.0 | 0 |
| CCN3-201 | CCN3 | P48745 | CCN family member 3 | chr8 | GO:0045597 | Not Cancer Driver | No | 49 | 0.1372549019607843 | 20 | 2 | 0.0056022408963585 | 0 |
| CCN4-202 | CCN4 | O95388 | CCN family member 4 | chr8 | GO:0045597 | Not Cancer Driver | No | 84 | 0.2288828337874659 | 20 | 7 | 0.0190735694822888 | 0 |
| CCN5-201 | CCN5 | O76076 | CCN family member 5 | chr20 | GO:0045597 | Not Cancer Driver | No | 37 | 0.148 | 22 | 3 | 0.012 | 0 |
| CCN6-203 | CCN6 | O95389 | Cellular communication network factor 6 | chr6 | GO:0045597 | Not Cancer Driver | No | 26 | 0.0734463276836158 | 11 | 0 | 0.0 | 6 |
| CDX2-201 | CDX2 | Q99626 | Homeobox protein CDX-2 | chr13 | GO:0045597 | Census, Compendium | Yes | 15 | 0.047923322683706 | 272 | 13 | 0.0415335463258785 | 0 |
| CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0045597 | Census, Compendium | Yes | 363 | 0.4647887323943662 | 288 | 291 | 0.3725992317541613 | 11 |
| DLX1-203 | DLX1 | P56177 | Homeobox protein DLX-1 | chr2 | GO:0045597 | Not Cancer Driver | No | 21 | 0.0823529411764705 | 183 | 17 | 0.0666666666666666 | 0 |
| DLX2-201 | DLX2 | Q07687 | Homeobox protein DLX-2 | chr2 | GO:0045597 | Not Cancer Driver | No | 33 | 0.1006097560975609 | 264 | 24 | 0.073170731707317 | 0 |
| DPF1-201 | DPF1 | Q92782 | Zinc finger protein neuro-d4 | chr19 | GO:0045597 | Not Cancer Driver | No | 27 | 0.0697674418604651 | 85 | 7 | 0.0180878552971576 | 0 |
| DPF3-209 | DPF3 | Q92784 | Zinc finger protein DPF3 | chr14 | GO:0045597 | Not Cancer Driver | No | 51 | 0.1349206349206349 | 172 | 29 | 0.0767195767195767 | 0 |
| EDN3-202 | EDN3 | P14138 | Endothelin-3 | chr20 | GO:0045597 | Not Cancer Driver | No | 51 | 0.2142857142857142 | 140 | 36 | 0.1512605042016806 | 3 |
| FGF8-202 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | GO:0045597 | Not Cancer Driver | No | 27 | 0.1158798283261802 | 79 | 8 | 0.0343347639484978 | 6 |
| FGFR1-214 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0045597 | Census, Compendium | Yes | 92 | 0.1119221411192214 | 231 | 26 | 0.0316301703163017 | 69 |
| GDNF-201 | GDNF | P39905 | Glial cell line-derived neurotrophic factor | chr5 | GO:0045597 | Not Cancer Driver | No | 43 | 0.2037914691943128 | 83 | 16 | 0.0758293838862559 | 2 |
| GHR-201 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0045597 | Not Cancer Driver | No | 139 | 0.2178683385579937 | 229 | 59 | 0.0924764890282131 | 19 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0045597 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HSP90AB1-203 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | GO:0045597 | Census, Compendium | Yes | 70 | 0.0966850828729281 | 255 | 29 | 0.0400552486187845 | 0 |
| INS-202 | INS | P01308 | Insulin | chr11 | GO:0045597 | Not Cancer Driver | No | 7 | 0.0636363636363636 | 5 | 1 | 0.009090909090909 | 19 |
| INSM1-201 | INSM1 | Q01101 | Insulinoma-associated protein 1 | chr20 | GO:0045597 | Not Cancer Driver | No | 23 | 0.0450980392156862 | 360 | 11 | 0.0215686274509803 | 0 |
| ISL1-201 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0045597 | Not Cancer Driver | No | 73 | 0.2091690544412607 | 181 | 41 | 0.1174785100286533 | 0 |
| JAK2-201 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0045597 | Census, Compendium | Yes | 81 | 0.0715547703180212 | 59 | 4 | 0.0035335689045936 | 4 |
| JUNB-201 | JUNB | P17275 | Transcription factor JunB | chr19 | GO:0045597 | Not Cancer Driver | No | 20 | 0.0576368876080691 | 305 | 18 | 0.0518731988472622 | 0 |
| LEF1-201 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0045597 | Census | Yes | 51 | 0.1278195488721804 | 372 | 47 | 0.1177944862155388 | 0 |
| NEUROD1-201 | NEUROD1 | Q13562 | Neurogenic differentiation factor 1 | chr2 | GO:0045597 | Not Cancer Driver | No | 68 | 0.1910112359550561 | 203 | 42 | 0.1179775280898876 | 2 |
| NEUROD4-201 | NEUROD4 | Q9HD90 | Neurogenic differentiation factor 4 | chr12 | GO:0045597 | Not Cancer Driver | No | 89 | 0.2688821752265861 | 237 | 62 | 0.1873111782477341 | 0 |
| NF2-202 | NF2 | P35240 | Merlin | chr22 | GO:0045597 | Census, Compendium | Yes | 49 | 0.0823529411764705 | 252 | 18 | 0.0302521008403361 | 16 |
| PA2G4-201 | PA2G4 | Q9UQ80 | Proliferation-associated protein 2G4 | chr12 | GO:0045597 | Not Cancer Driver | No | 36 | 0.0913705583756345 | 128 | 12 | 0.0304568527918781 | 0 |
| PBRM1-201 | PBRM1 | Q86U86 | Protein polybromo-1 | chr3 | GO:0045597 | Census, Compendium | Yes | 162 | 0.0959147424511545 | 704 | 61 | 0.0361160449970396 | 0 |
| PHF10-201 | PHF10 | Q8WUB8 | PHD finger protein 10 | chr6 | GO:0045597 | Not Cancer Driver | No | 27 | 0.0542168674698795 | 298 | 21 | 0.0421686746987951 | 0 |
| POU4F2-201 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0045597 | Not Cancer Driver | No | 96 | 0.2347188264058679 | 311 | 64 | 0.1564792176039119 | 0 |
| PPP1R13L-201 | PPP1R13L | Q8WUF5 | RelA-associated inhibitor | chr19 | GO:0045597 | Not Cancer Driver | No | 93 | 0.1123188405797101 | 659 | 75 | 0.0905797101449275 | 0 |
| RPS6KA1-204 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | GO:0045597 | Not Cancer Driver | No | 71 | 0.0965986394557823 | 178 | 22 | 0.0299319727891156 | 0 |
| RPS6KA3-201 | RPS6KA3 | P51812 | Ribosomal protein S6 kinase alpha-3 | chrX | GO:0045597 | Compendium | Yes | 72 | 0.0972972972972973 | 146 | 10 | 0.0135135135135135 | 13 |
| SERPINF2-204 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0045597 | Not Cancer Driver | No | 46 | 0.0936863543788187 | 113 | 14 | 0.0285132382892057 | 1 |
| SLC6A6-210 | SLC6A6 | P31641 | Sodium- and chloride-dependent taurine transporter | chr3 | GO:0045597 | Not Cancer Driver | No | 61 | 0.0983870967741935 | 22 | 1 | 0.0016129032258064 | 2 |
| SMARCA2-203 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | GO:0045597 | Not Cancer Driver | No | 178 | 0.1119496855345912 | 1015 | 100 | 0.0628930817610062 | 36 |
| SMARCA4-201 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | GO:0045597 | Census, Compendium | Yes | 300 | 0.1821493624772313 | 1078 | 163 | 0.0989678202792957 | 5 |
| SMARCB1-213 | SMARCB1 | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | chr22 | GO:0045597 | Census, Compendium | Yes | 55 | 0.1428571428571428 | 141 | 26 | 0.0675324675324675 | 3 |
| SMARCC1-201 | SMARCC1 | Q92922 | SWI/SNF complex subunit SMARCC1 | chr3 | GO:0045597 | Not Cancer Driver | No | 80 | 0.0723981900452488 | 721 | 50 | 0.0452488687782805 | 2 |
| SMARCC2-201 | SMARCC2 | Q8TAQ2 | SWI/SNF complex subunit SMARCC2 | chr12 | GO:0045597 | Not Cancer Driver | No | 99 | 0.0815485996705107 | 875 | 71 | 0.058484349258649 | 4 |
| SMARCD1-202 | SMARCD1 | Q96GM5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 | chr12 | GO:0045597 | Census, Compendium | Yes | 37 | 0.0718446601941747 | 216 | 14 | 0.0271844660194174 | 2 |
| SMARCD2-203 | SMARCD2 | Q92925 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 | chr17 | GO:0045597 | Not Cancer Driver | No | 42 | 0.0790960451977401 | 251 | 15 | 0.0282485875706214 | 0 |
| SMARCD3-201 | SMARCD3 | Q6STE5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 | chr7 | GO:0045597 | Not Cancer Driver | No | 41 | 0.0848861283643892 | 213 | 10 | 0.020703933747412 | 0 |
| SMARCE1-202 | SMARCE1 | Q969G3 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | chr17 | GO:0045597 | Census | Yes | 36 | 0.0875912408759124 | 332 | 28 | 0.0681265206812652 | 1 |
| SOCS3-201 | SOCS3 | O14543 | Suppressor of cytokine signaling 3 | chr17 | GO:0045597 | Not Cancer Driver | No | 24 | 0.1066666666666666 | 111 | 11 | 0.0488888888888888 | 0 |
| SOX2-201 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | GO:0045597 | Census | Yes | 32 | 0.1009463722397476 | 312 | 32 | 0.1009463722397476 | 0 |
| SRF-201 | SRF | P11831 | Serum response factor | chr6 | GO:0045597 | Not Cancer Driver | No | 30 | 0.0590551181102362 | 443 | 29 | 0.0570866141732283 | 0 |
| VHL-201 | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | GO:0045597 | Census, Compendium | Yes | 85 | 0.3990610328638497 | 117 | 15 | 0.0704225352112676 | 84 |
| ZNF268-205 | ZNF268 | Q14587 | Zinc finger protein 268 | chr12 | GO:0045597 | Not Cancer Driver | No | 55 | 0.058078141499472 | 63 | 5 | 0.0052798310454065 | 0 |