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Total number of protein in "GO:0045599" GO term:  48

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADIPOQ-201 ADIPOQ Q15848 Adiponectin chr3 GO:0045599 Not Cancer Driver No 32 0.1311475409836065 92 16 0.0655737704918032 1
ANKRD26-201 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 GO:0045599 Not Cancer Driver No 156 0.0912280701754386 1279 115 0.067251461988304 0
ASXL1-202 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0045599 Census, Compendium Yes 145 0.0940947436729396 1307 125 0.081116158338741 0
AXIN1-201 AXIN1 O15169 Axin-1 chr16 GO:0045599 Census, Compendium Yes 91 0.105568445475638 623 69 0.0800464037122969 4
BBS12-201 BBS12 Q6ZW61 Bardet-Biedl syndrome 12 protein chr4 GO:0045599 Not Cancer Driver No 60 0.0845070422535211 34 2 0.0028169014084507 10
BMAL1-203 BMAL1 O00327 Basic helix-loop-helix ARNT-like protein 1 chr11 GO:0045599 Not Cancer Driver No 54 0.0862619808306709 332 31 0.0495207667731629 0
BMP2-201 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0045599 Not Cancer Driver No 54 0.1363636363636363 140 22 0.0555555555555555 0
C1QL4-201 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 GO:0045599 Not Cancer Driver No 17 0.0714285714285714 101 3 0.0126050420168067 0
CCDC85B-201 CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 GO:0045599 Not Cancer Driver No 3 0.0148514851485148 81 2 0.0099009900990099 0
CCN4-202 CCN4 O95388 CCN family member 4 chr8 GO:0045599 Not Cancer Driver No 84 0.2288828337874659 20 7 0.0190735694822888 0
DDIT3-201 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0045599 Census Yes 19 0.1124260355029585 161 17 0.1005917159763313 0
E2F1-201 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0045599 Not Cancer Driver No 39 0.0892448512585812 273 17 0.0389016018306636 0
ENPP1-204 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0045599 Not Cancer Driver No 114 0.1232432432432432 101 3 0.0032432432432432 32
FERMT2-201 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0045599 Not Cancer Driver No 44 0.0647058823529411 102 8 0.0117647058823529 0
FOXO1-201 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0045599 Census, Compendium Yes 52 0.0793893129770992 586 51 0.0778625954198473 0
GPER1-202 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0045599 Not Cancer Driver No 47 0.1253333333333333 13 4 0.0106666666666666 0
GPS2-201 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0045599 Not Cancer Driver No 20 0.0611620795107033 320 18 0.055045871559633 0
ID4-201 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0045599 Not Cancer Driver No 5 0.031055900621118 72 1 0.0062111801242236 0
IL6-201 IL6 P05231 Interleukin-6 chr7 GO:0045599 Not Cancer Driver No 32 0.1509433962264151 58 6 0.0283018867924528 0
INSIG1-201 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0045599 Not Cancer Driver No 25 0.0902527075812274 43 1 0.003610108303249 0
JAG1-201 JAG1 P78504 Protein jagged-1 chr20 GO:0045599 Not Cancer Driver No 133 0.1091954022988505 172 14 0.0114942528735632 45
JDP2-208 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0045599 Not Cancer Driver No 16 0.0981595092024539 142 13 0.0797546012269938 0
LRP3-201 LRP3 O75074 Low-density lipoprotein receptor-related protein 3 chr19 GO:0045599 Not Cancer Driver No 57 0.074025974025974 214 12 0.0155844155844155 0
MMP11-201 MMP11 P24347 Stromelysin-3 chr22 GO:0045599 Not Cancer Driver No 47 0.096311475409836 122 13 0.026639344262295 0
MSX2-201 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0045599 Not Cancer Driver No 21 0.0786516853932584 170 10 0.0374531835205992 3
PTGR3-201 PTGR3 Q8N4Q0 Prostaglandin reductase 3 chr18 GO:0045599 Not Cancer Driver No 26 0.0689655172413793 0 0 0.0 0
RORA-203 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0045599 Not Cancer Driver No 43 0.0822179732313575 181 11 0.0210325047801147 4
RUNX1T1-245 RUNX1T1 Q06455 Protein CBFA2T1 chr8 GO:0045599 Census, Compendium Yes 216 0.3576158940397351 469 171 0.2831125827814569 0
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0045599 Not Cancer Driver No 43 0.0575635876840696 435 19 0.0254350736278447 0
SIRT2-201 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0045599 Not Cancer Driver No 40 0.1028277634961439 85 13 0.0334190231362467 0
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0045599 Census, Compendium Yes 80 0.188235294117647 113 15 0.0352941176470588 5
SOD2-210 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0045599 Not Cancer Driver No 21 0.0945945945945946 25 3 0.0135135135135135 0
SORT1-201 SORT1 Q99523 Sortilin chr1 GO:0045599 Not Cancer Driver No 54 0.0649819494584837 110 0 0.0 0
TGFB1-201 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0045599 Not Cancer Driver No 30 0.0769230769230769 44 3 0.0076923076923076 8
TGFB1I1-203 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0045599 Not Cancer Driver No 49 0.106290672451193 219 27 0.0585683297180043 0
TLCD3B-202 TLCD3B Q71RH2 Ceramide synthase chr16 GO:0045599 Not Cancer Driver No 33 0.1204379562043795 6 2 0.0072992700729927 0
TNF-208 TNF P01375 Tumor necrosis factor chr6 GO:0045599 Not Cancer Driver No 22 0.0944206008583691 45 2 0.0085836909871244 0
TRIB2-201 TRIB2 Q92519 Tribbles homolog 2 chr2 GO:0045599 Not Cancer Driver No 41 0.119533527696793 43 4 0.0116618075801749 0
TRIB3-201 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0045599 Not Cancer Driver No 45 0.1256983240223463 113 17 0.047486033519553 0
TRIO-202 TRIO O75962 Triple functional domain protein chr5 GO:0045599 Not Cancer Driver No 303 0.0978366160800774 1054 88 0.0284145947691314 8
WNT1-201 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0045599 Not Cancer Driver No 20 0.054054054054054 25 0 0.0 8
WNT10B-201 WNT10B O00744 Protein Wnt-10b chr12 GO:0045599 Not Cancer Driver No 45 0.1156812339331619 84 14 0.0359897172236503 2
WNT3A-201 WNT3A P56704 Protein Wnt-3a chr1 GO:0045599 Not Cancer Driver No 60 0.1704545454545454 37 2 0.0056818181818181 0
WNT5A-201 WNT5A P41221 Protein Wnt-5a chr3 GO:0045599 Not Cancer Driver No 42 0.1105263157894736 0 0 0.0 2
WWTR1-201 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0045599 Census Yes 29 0.0725 389 29 0.0725 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0045599 Not Cancer Driver No 41 0.0813492063492063 491 41 0.0813492063492063 0
ZFP36L2-201 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0045599 Not Cancer Driver No 61 0.1234817813765182 325 42 0.0850202429149797 0
ZFPM2-201 ZFPM2 Q8WW38 Zinc finger protein ZFPM2 chr8 GO:0045599 Not Cancer Driver No 310 0.2693310165073849 660 195 0.1694178974804517 8