Total number of protein in "GO:0045599" GO term: 48
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADIPOQ-201 | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0045599 | Not Cancer Driver | No | 32 | 0.1311475409836065 | 92 | 16 | 0.0655737704918032 | 1 |
ANKRD26-201 | ANKRD26 | Q9UPS8 | Ankyrin repeat domain-containing protein 26 | chr10 | GO:0045599 | Not Cancer Driver | No | 156 | 0.0912280701754386 | 1279 | 115 | 0.067251461988304 | 0 |
ASXL1-202 | ASXL1 | Q8IXJ9 | Polycomb group protein ASXL1 | chr20 | GO:0045599 | Census, Compendium | Yes | 145 | 0.0940947436729396 | 1307 | 125 | 0.081116158338741 | 0 |
AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0045599 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
BBS12-201 | BBS12 | Q6ZW61 | Bardet-Biedl syndrome 12 protein | chr4 | GO:0045599 | Not Cancer Driver | No | 60 | 0.0845070422535211 | 34 | 2 | 0.0028169014084507 | 10 |
BMAL1-203 | BMAL1 | O00327 | Basic helix-loop-helix ARNT-like protein 1 | chr11 | GO:0045599 | Not Cancer Driver | No | 54 | 0.0862619808306709 | 332 | 31 | 0.0495207667731629 | 0 |
BMP2-201 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0045599 | Not Cancer Driver | No | 54 | 0.1363636363636363 | 140 | 22 | 0.0555555555555555 | 0 |
C1QL4-201 | C1QL4 | Q86Z23 | Complement C1q-like protein 4 | chr12 | GO:0045599 | Not Cancer Driver | No | 17 | 0.0714285714285714 | 101 | 3 | 0.0126050420168067 | 0 |
CCDC85B-201 | CCDC85B | Q15834 | Coiled-coil domain-containing protein 85B | chr11 | GO:0045599 | Not Cancer Driver | No | 3 | 0.0148514851485148 | 81 | 2 | 0.0099009900990099 | 0 |
CCN4-202 | CCN4 | O95388 | CCN family member 4 | chr8 | GO:0045599 | Not Cancer Driver | No | 84 | 0.2288828337874659 | 20 | 7 | 0.0190735694822888 | 0 |
DDIT3-201 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0045599 | Census | Yes | 19 | 0.1124260355029585 | 161 | 17 | 0.1005917159763313 | 0 |
E2F1-201 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:0045599 | Not Cancer Driver | No | 39 | 0.0892448512585812 | 273 | 17 | 0.0389016018306636 | 0 |
ENPP1-204 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0045599 | Not Cancer Driver | No | 114 | 0.1232432432432432 | 101 | 3 | 0.0032432432432432 | 32 |
FERMT2-201 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0045599 | Not Cancer Driver | No | 44 | 0.0647058823529411 | 102 | 8 | 0.0117647058823529 | 0 |
FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0045599 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
GPER1-202 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0045599 | Not Cancer Driver | No | 47 | 0.1253333333333333 | 13 | 4 | 0.0106666666666666 | 0 |
GPS2-201 | GPS2 | Q13227 | G protein pathway suppressor 2 | chr17 | GO:0045599 | Not Cancer Driver | No | 20 | 0.0611620795107033 | 320 | 18 | 0.055045871559633 | 0 |
ID4-201 | ID4 | P47928 | DNA-binding protein inhibitor ID-4 | chr6 | GO:0045599 | Not Cancer Driver | No | 5 | 0.031055900621118 | 72 | 1 | 0.0062111801242236 | 0 |
IL6-201 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0045599 | Not Cancer Driver | No | 32 | 0.1509433962264151 | 58 | 6 | 0.0283018867924528 | 0 |
INSIG1-201 | INSIG1 | O15503 | Insulin-induced gene 1 protein | chr7 | GO:0045599 | Not Cancer Driver | No | 25 | 0.0902527075812274 | 43 | 1 | 0.003610108303249 | 0 |
JAG1-201 | JAG1 | P78504 | Protein jagged-1 | chr20 | GO:0045599 | Not Cancer Driver | No | 133 | 0.1091954022988505 | 172 | 14 | 0.0114942528735632 | 45 |
JDP2-208 | JDP2 | Q8WYK2 | Jun dimerization protein 2 | chr14 | GO:0045599 | Not Cancer Driver | No | 16 | 0.0981595092024539 | 142 | 13 | 0.0797546012269938 | 0 |
LRP3-201 | LRP3 | O75074 | Low-density lipoprotein receptor-related protein 3 | chr19 | GO:0045599 | Not Cancer Driver | No | 57 | 0.074025974025974 | 214 | 12 | 0.0155844155844155 | 0 |
MMP11-201 | MMP11 | P24347 | Stromelysin-3 | chr22 | GO:0045599 | Not Cancer Driver | No | 47 | 0.096311475409836 | 122 | 13 | 0.026639344262295 | 0 |
MSX2-201 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0045599 | Not Cancer Driver | No | 21 | 0.0786516853932584 | 170 | 10 | 0.0374531835205992 | 3 |
PTGR3-201 | PTGR3 | Q8N4Q0 | Prostaglandin reductase 3 | chr18 | GO:0045599 | Not Cancer Driver | No | 26 | 0.0689655172413793 | 0 | 0 | 0.0 | 0 |
RORA-203 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0045599 | Not Cancer Driver | No | 43 | 0.0822179732313575 | 181 | 11 | 0.0210325047801147 | 4 |
RUNX1T1-245 | RUNX1T1 | Q06455 | Protein CBFA2T1 | chr8 | GO:0045599 | Census, Compendium | Yes | 216 | 0.3576158940397351 | 469 | 171 | 0.2831125827814569 | 0 |
SIRT1-201 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0045599 | Not Cancer Driver | No | 43 | 0.0575635876840696 | 435 | 19 | 0.0254350736278447 | 0 |
SIRT2-201 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0045599 | Not Cancer Driver | No | 40 | 0.1028277634961439 | 85 | 13 | 0.0334190231362467 | 0 |
SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0045599 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
SOD2-210 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0045599 | Not Cancer Driver | No | 21 | 0.0945945945945946 | 25 | 3 | 0.0135135135135135 | 0 |
SORT1-201 | SORT1 | Q99523 | Sortilin | chr1 | GO:0045599 | Not Cancer Driver | No | 54 | 0.0649819494584837 | 110 | 0 | 0.0 | 0 |
TGFB1-201 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0045599 | Not Cancer Driver | No | 30 | 0.0769230769230769 | 44 | 3 | 0.0076923076923076 | 8 |
TGFB1I1-203 | TGFB1I1 | O43294 | Transforming growth factor beta-1-induced transcript 1 protein | chr16 | GO:0045599 | Not Cancer Driver | No | 49 | 0.106290672451193 | 219 | 27 | 0.0585683297180043 | 0 |
TLCD3B-202 | TLCD3B | Q71RH2 | Ceramide synthase | chr16 | GO:0045599 | Not Cancer Driver | No | 33 | 0.1204379562043795 | 6 | 2 | 0.0072992700729927 | 0 |
TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0045599 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
TRIB2-201 | TRIB2 | Q92519 | Tribbles homolog 2 | chr2 | GO:0045599 | Not Cancer Driver | No | 41 | 0.119533527696793 | 43 | 4 | 0.0116618075801749 | 0 |
TRIB3-201 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0045599 | Not Cancer Driver | No | 45 | 0.1256983240223463 | 113 | 17 | 0.047486033519553 | 0 |
TRIO-202 | TRIO | O75962 | Triple functional domain protein | chr5 | GO:0045599 | Not Cancer Driver | No | 303 | 0.0978366160800774 | 1054 | 88 | 0.0284145947691314 | 8 |
WNT1-201 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0045599 | Not Cancer Driver | No | 20 | 0.054054054054054 | 25 | 0 | 0.0 | 8 |
WNT10B-201 | WNT10B | O00744 | Protein Wnt-10b | chr12 | GO:0045599 | Not Cancer Driver | No | 45 | 0.1156812339331619 | 84 | 14 | 0.0359897172236503 | 2 |
WNT3A-201 | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0045599 | Not Cancer Driver | No | 60 | 0.1704545454545454 | 37 | 2 | 0.0056818181818181 | 0 |
WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0045599 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |
WWTR1-201 | WWTR1 | Q9GZV5 | WW domain-containing transcription regulator protein 1 | chr3 | GO:0045599 | Census | Yes | 29 | 0.0725 | 389 | 29 | 0.0725 | 0 |
YAP1-201 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0045599 | Not Cancer Driver | No | 41 | 0.0813492063492063 | 491 | 41 | 0.0813492063492063 | 0 |
ZFP36L2-201 | ZFP36L2 | P47974 | mRNA decay activator protein ZFP36L2 | chr2 | GO:0045599 | Not Cancer Driver | No | 61 | 0.1234817813765182 | 325 | 42 | 0.0850202429149797 | 0 |
ZFPM2-201 | ZFPM2 | Q8WW38 | Zinc finger protein ZFPM2 | chr8 | GO:0045599 | Not Cancer Driver | No | 310 | 0.2693310165073849 | 660 | 195 | 0.1694178974804517 | 8 |