Total number of protein in "GO:0045665" GO term: 60
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0045665 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
| ASCL1-201 | ASCL1 | P50553 | Achaete-scute homolog 1 | chr12 | GO:0045665 | Not Cancer Driver | No | 26 | 0.1101694915254237 | 183 | 18 | 0.0762711864406779 | 0 |
| ASPM-203 | ASPM | Q8IZT6 | Abnormal spindle-like microcephaly-associated protein | chr1 | GO:0045665 | Not Cancer Driver | No | 380 | 0.1092896174863388 | 427 | 47 | 0.0135174000575208 | 0 |
| BMP7-201 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0045665 | Not Cancer Driver | No | 68 | 0.1577726218097447 | 69 | 13 | 0.0301624129930394 | 0 |
| CALR-201 | CALR | P27797 | Calreticulin | chr19 | GO:0045665 | Census | Yes | 28 | 0.0671462829736211 | 245 | 16 | 0.0383693045563549 | 0 |
| CDK5RAP2-201 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | GO:0045665 | Not Cancer Driver | No | 150 | 0.0792393026941362 | 1142 | 92 | 0.0486001056524035 | 0 |
| CNTN4-203 | CNTN4 | Q8IWV2 | Contactin-4 | chr3 | GO:0045665 | Not Cancer Driver | No | 247 | 0.2407407407407407 | 303 | 72 | 0.0701754385964912 | 0 |
| CTDSP1-201 | CTDSP1 | Q9GZU7 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | chr2 | GO:0045665 | Not Cancer Driver | No | 30 | 0.1149425287356321 | 46 | 1 | 0.003831417624521 | 0 |
| DDX6-206 | DDX6 | P26196 | Probable ATP-dependent RNA helicase DDX6 | chr11 | GO:0045665 | Census, Compendium | Yes | 29 | 0.0600414078674948 | 129 | 6 | 0.0124223602484472 | 4 |
| DISP3-201 | DISP3 | Q9P2K9 | Protein dispatched homolog 3 | chr1 | GO:0045665 | Not Cancer Driver | No | 268 | 0.1925287356321839 | 174 | 34 | 0.0244252873563218 | 0 |
| DIXDC1-201 | DIXDC1 | Q155Q3 | Dixin | chr11 | GO:0045665 | Not Cancer Driver | No | 55 | 0.0805270863836017 | 498 | 44 | 0.0644216691068814 | 0 |
| DLL1-201 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0045665 | Not Cancer Driver | No | 81 | 0.1120331950207468 | 145 | 15 | 0.0207468879668049 | 1 |
| DTX1-204 | DTX1 | Q86Y01 | E3 ubiquitin-protein ligase DTX1 | chr12 | GO:0045665 | Compendium | Yes | 78 | 0.1258064516129032 | 304 | 34 | 0.0548387096774193 | 0 |
| EIF2AK4-201 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0045665 | Not Cancer Driver | No | 113 | 0.0685263796240145 | 496 | 34 | 0.0206185567010309 | 2 |
| EIF4E-203 | EIF4E | P06730 | Eukaryotic translation initiation factor 4E | chr4 | GO:0045665 | Not Cancer Driver | No | 18 | 0.0829493087557603 | 54 | 4 | 0.0184331797235023 | 0 |
| EIF4ENIF1-201 | EIF4ENIF1 | Q9NRA8 | Eukaryotic translation initiation factor 4E transporter | chr22 | GO:0045665 | Not Cancer Driver | No | 86 | 0.0873096446700507 | 902 | 75 | 0.0761421319796954 | 0 |
| FEZF2-201 | FEZF2 | Q8TBJ5 | Fez family zinc finger protein 2 | chr3 | GO:0045665 | Not Cancer Driver | No | 49 | 0.1067538126361655 | 144 | 13 | 0.0283224400871459 | 0 |
| FOXG1-201 | FOXG1 | P55316 | Forkhead box protein G1 | chr14 | GO:0045665 | Not Cancer Driver | No | 99 | 0.2024539877300613 | 322 | 53 | 0.1083844580777096 | 3 |
| FOXO3-202 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0045665 | Census, Compendium | Yes | 54 | 0.0802377414561664 | 597 | 50 | 0.0742942050520059 | 0 |
| GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0045665 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
| GPR37L1-201 | GPR37L1 | O60883 | G-protein coupled receptor 37-like 1 | chr1 | GO:0045665 | Not Cancer Driver | No | 43 | 0.0893970893970894 | 82 | 7 | 0.0145530145530145 | 0 |
| HES1-201 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0045665 | Not Cancer Driver | No | 35 | 0.125 | 227 | 30 | 0.1071428571428571 | 0 |
| HES5-201 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0045665 | Not Cancer Driver | No | 1 | 0.0060240963855421 | 73 | 0 | 0.0 | 0 |
| HEY1-202 | HEY1 | Q9Y5J3 | Hairy/enhancer-of-split related with YRPW motif protein 1 | chr8 | GO:0045665 | Census | Yes | 26 | 0.0855263157894736 | 172 | 12 | 0.0394736842105263 | 0 |
| HMG20A-201 | HMG20A | Q9NP66 | High mobility group protein 20A | chr15 | GO:0045665 | Not Cancer Driver | No | 40 | 0.1152737752161383 | 308 | 34 | 0.0979827089337175 | 0 |
| HOXA2-201 | HOXA2 | O43364 | Homeobox protein Hox-A2 | chr7 | GO:0045665 | Not Cancer Driver | No | 49 | 0.1303191489361702 | 281 | 39 | 0.1037234042553191 | 1 |
| ID4-201 | ID4 | P47928 | DNA-binding protein inhibitor ID-4 | chr6 | GO:0045665 | Not Cancer Driver | No | 5 | 0.031055900621118 | 72 | 1 | 0.0062111801242236 | 0 |
| IRX3-201 | IRX3 | P78415 | Iroquois-class homeodomain protein IRX-3 | chr16 | GO:0045665 | Not Cancer Driver | No | 23 | 0.0459081836327345 | 410 | 21 | 0.0419161676646706 | 0 |
| ISL1-201 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0045665 | Not Cancer Driver | No | 73 | 0.2091690544412607 | 181 | 41 | 0.1174785100286533 | 0 |
| ISL2-201 | ISL2 | Q96A47 | Insulin gene enhancer protein ISL-2 | chr15 | GO:0045665 | Not Cancer Driver | No | 20 | 0.0557103064066852 | 168 | 10 | 0.0278551532033426 | 0 |
| ITGB1-201 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0045665 | Not Cancer Driver | No | 73 | 0.0914786967418546 | 84 | 8 | 0.0100250626566416 | 0 |
| JAG1-201 | JAG1 | P78504 | Protein jagged-1 | chr20 | GO:0045665 | Not Cancer Driver | No | 133 | 0.1091954022988505 | 172 | 14 | 0.0114942528735632 | 45 |
| LMX1A-202 | LMX1A | Q8TE12 | LIM homeobox transcription factor 1-alpha | chr1 | GO:0045665 | Not Cancer Driver | No | 95 | 0.2486910994764398 | 187 | 55 | 0.143979057591623 | 1 |
| LSM1-201 | LSM1 | O15116 | U6 snRNA-associated Sm-like protein LSm1 | chr8 | GO:0045665 | Not Cancer Driver | No | 15 | 0.112781954887218 | 6 | 1 | 0.0075187969924812 | 0 |
| MAG-202 | MAG | P20916 | Myelin-associated glycoprotein | chr19 | GO:0045665 | Not Cancer Driver | No | 101 | 0.1613418530351437 | 65 | 9 | 0.0143769968051118 | 1 |
| MED1-201 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0045665 | Not Cancer Driver | No | 81 | 0.0512333965844402 | 1104 | 50 | 0.0316255534471853 | 0 |
| MEIS1-201 | MEIS1 | O00470 | Homeobox protein Meis1 | chr2 | GO:0045665 | Not Cancer Driver | No | 67 | 0.1717948717948718 | 268 | 51 | 0.1307692307692307 | 0 |
| MIB1-201 | MIB1 | Q86YT6 | E3 ubiquitin-protein ligase MIB1 | chr18 | GO:0045665 | Not Cancer Driver | No | 96 | 0.0954274353876739 | 284 | 26 | 0.025844930417495 | 1 |
| NEPRO-201 | NEPRO | Q6NW34 | Nucleolus and neural progenitor protein | chr3 | GO:0045665 | Not Cancer Driver | No | 44 | 0.0776014109347442 | 148 | 21 | 0.037037037037037 | 0 |
| NKX2-2-201 | NKX2-2 | O95096 | Homeobox protein Nkx-2.2 | chr20 | GO:0045665 | Not Cancer Driver | No | 71 | 0.2600732600732601 | 206 | 55 | 0.2014652014652014 | 0 |
| NOTCH3-201 | NOTCH3 | Q9UM47 | Neurogenic locus notch homolog protein 3 | chr19 | GO:0045665 | Not Cancer Driver | No | 241 | 0.1038345540715209 | 560 | 61 | 0.0262817750969409 | 89 |
| NR2E1-202 | NR2E1 | Q9Y466 | Nuclear receptor subfamily 2 group E member 1 | chr6 | GO:0045665 | Not Cancer Driver | No | 45 | 0.1168831168831168 | 57 | 3 | 0.0077922077922077 | 0 |
| OLIG2-202 | OLIG2 | Q13516 | Oligodendrocyte transcription factor 2 | chr21 | GO:0045665 | Census | Yes | 20 | 0.0619195046439628 | 256 | 20 | 0.0619195046439628 | 0 |
| PAX6-203 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0045665 | Not Cancer Driver | No | 51 | 0.1208530805687203 | 338 | 37 | 0.0876777251184834 | 35 |
| PBX1-203 | PBX1 | P40424 | Pre-B-cell leukemia transcription factor 1 | chr1 | GO:0045665 | Census | Yes | 64 | 0.1488372093023255 | 291 | 44 | 0.1023255813953488 | 0 |
| PHOX2B-201 | PHOX2B | Q99453 | Paired mesoderm homeobox protein 2B | chr4 | GO:0045665 | Census | Yes | 23 | 0.0732484076433121 | 219 | 12 | 0.0382165605095541 | 2 |
| PTBP1-203 | PTBP1 | P26599 | Polypyrimidine tract-binding protein 1 | chr19 | GO:0045665 | Not Cancer Driver | No | 65 | 0.1166965888689407 | 162 | 14 | 0.0251346499102333 | 0 |
| RAP1GAP-205 | RAP1GAP | P47736 | Rap1 GTPase-activating protein 1 | chr1 | GO:0045665 | Not Cancer Driver | No | 64 | 0.0965309200603318 | 313 | 30 | 0.0452488687782805 | 0 |
| REST-201 | REST | Q13127 | RE1-silencing transcription factor | chr4 | GO:0045665 | Not Cancer Driver | No | 86 | 0.0783956244302643 | 872 | 68 | 0.0619872379216043 | 4 |
| SHOC2-202 | SHOC2 | Q9UQ13 | Leucine-rich repeat protein SHOC-2 | chr10 | GO:0045665 | Not Cancer Driver | No | 38 | 0.0652920962199312 | 110 | 9 | 0.0154639175257731 | 2 |
| SIX3-201 | SIX3 | O95343 | Homeobox protein SIX3 | chr2 | GO:0045665 | Not Cancer Driver | No | 36 | 0.108433734939759 | 198 | 16 | 0.0481927710843373 | 29 |
| SLC6A4-206 | SLC6A4 | P31645 | Sodium-dependent serotonin transporter | chr17 | GO:0045665 | Not Cancer Driver | No | 77 | 0.1222222222222222 | 76 | 7 | 0.0111111111111111 | 0 |
| SOX2-201 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | GO:0045665 | Census | Yes | 32 | 0.1009463722397476 | 312 | 32 | 0.1009463722397476 | 0 |
| SOX3-201 | SOX3 | P41225 | Transcription factor SOX-3 | chrX | GO:0045665 | Not Cancer Driver | No | 52 | 0.116591928251121 | 344 | 51 | 0.1143497757847533 | 0 |
| SPAG9-201 | SPAG9 | O60271 | C-Jun-amino-terminal kinase-interacting protein 4 | chr17 | GO:0045665 | Not Cancer Driver | No | 95 | 0.0719152157456472 | 844 | 62 | 0.0469341408024224 | 0 |
| TLX3-201 | TLX3 | O43711 | T-cell leukemia homeobox protein 3 | chr5 | GO:0045665 | Census | Yes | 33 | 0.1134020618556701 | 180 | 21 | 0.0721649484536082 | 0 |
| TP73-208 | TP73 | O15350 | Tumor protein p73 | chr1 | GO:0045665 | Not Cancer Driver | No | 67 | 0.1053459119496855 | 446 | 45 | 0.070754716981132 | 0 |
| TUNAR-202 | TUNAR | A0A1B0GTB2 | Protein TUNAR | chr14 | GO:0045665 | Not Cancer Driver | No | 0 | 0.0 | 18 | 0 | 0.0 | 0 |
| ZHX2-201 | ZHX2 | Q9Y6X8 | Zinc fingers and homeoboxes protein 2 | chr8 | GO:0045665 | Not Cancer Driver | No | 121 | 0.1445639187574671 | 600 | 83 | 0.0991636798088411 | 0 |
| ZNF536-201 | ZNF536 | O15090 | Zinc finger protein 536 | chr19 | GO:0045665 | Not Cancer Driver | No | 518 | 0.3984615384615385 | 993 | 386 | 0.2969230769230769 | 0 |