Total number of protein in "GO:0045668" GO term: 49
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AREG-201 | AREG | P15514 | Amphiregulin | chr4 | GO:0045668 | Not Cancer Driver | No | 33 | 0.1309523809523809 | 152 | 26 | 0.1031746031746031 | 0 |
| AXIN2-201 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | GO:0045668 | Census, Compendium | Yes | 82 | 0.0972716488730723 | 551 | 51 | 0.0604982206405693 | 0 |
| BAMBI-201 | BAMBI | Q13145 | BMP and activin membrane-bound inhibitor homolog | chr10 | GO:0045668 | Not Cancer Driver | No | 24 | 0.0923076923076923 | 31 | 5 | 0.0192307692307692 | 0 |
| CDK6-202 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:0045668 | Census | Yes | 25 | 0.0766871165644171 | 24 | 3 | 0.00920245398773 | 1 |
| CHRD-201 | CHRD | Q9H2X0 | Chordin | chr3 | GO:0045668 | Not Cancer Driver | No | 119 | 0.1246073298429319 | 309 | 42 | 0.043979057591623 | 0 |
| CITED1-211 | CITED1 | Q99966 | Cbp/p300-interacting transactivator 1 | chrX | GO:0045668 | Not Cancer Driver | No | 16 | 0.082901554404145 | 167 | 15 | 0.077720207253886 | 0 |
| CRIM1-201 | CRIM1 | Q9NZV1 | Cysteine-rich motor neuron 1 protein | chr2 | GO:0045668 | Not Cancer Driver | No | 106 | 0.1023166023166023 | 35 | 4 | 0.0038610038610038 | 0 |
| ERFE-207 | ERFE | Q4G0M1 | Erythroferrone | chr2 | GO:0045668 | Not Cancer Driver | No | 3 | 0.0084745762711864 | 180 | 0 | 0.0 | 0 |
| FGF23-201 | FGF23 | Q9GZV9 | Fibroblast growth factor 23 | chr12 | GO:0045668 | Not Cancer Driver | No | 83 | 0.3306772908366533 | 97 | 53 | 0.2111553784860557 | 6 |
| GREM1-203 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:0045668 | Not Cancer Driver | No | 21 | 0.1141304347826086 | 77 | 9 | 0.0489130434782608 | 0 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0045668 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HAND2-201 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | GO:0045668 | Not Cancer Driver | No | 39 | 0.1797235023041474 | 124 | 24 | 0.1105990783410138 | 0 |
| HDAC7-209 | HDAC7 | Q8WUI4 | Histone deacetylase 7 | chr12 | GO:0045668 | Not Cancer Driver | No | 70 | 0.0735294117647058 | 571 | 43 | 0.0451680672268907 | 0 |
| HOXA2-201 | HOXA2 | O43364 | Homeobox protein Hox-A2 | chr7 | GO:0045668 | Not Cancer Driver | No | 49 | 0.1303191489361702 | 281 | 39 | 0.1037234042553191 | 1 |
| ID3-201 | ID3 | Q02535 | DNA-binding protein inhibitor ID-3 | chr1 | GO:0045668 | Census, Compendium | Yes | 10 | 0.0840336134453781 | 34 | 3 | 0.0252100840336134 | 0 |
| IGFBP5-201 | IGFBP5 | P24593 | Insulin-like growth factor-binding protein 5 | chr2 | GO:0045668 | Not Cancer Driver | No | 23 | 0.0845588235294117 | 112 | 18 | 0.0661764705882353 | 0 |
| IPO7-201 | IPO7 | O95373 | Importin-7 | chr11 | GO:0045668 | Not Cancer Driver | No | 108 | 0.1040462427745664 | 202 | 25 | 0.0240847784200385 | 0 |
| LIMD1-201 | LIMD1 | Q9UGP4 | LIM domain-containing protein 1 | chr3 | GO:0045668 | Not Cancer Driver | No | 47 | 0.0695266272189349 | 430 | 29 | 0.0428994082840236 | 0 |
| LRP5-201 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0045668 | Not Cancer Driver | No | 196 | 0.1213622291021671 | 189 | 24 | 0.014860681114551 | 54 |
| MEN1-203 | MEN1 | O00255 | Menin | chr11 | GO:0045668 | Census, Compendium | Yes | 50 | 0.08130081300813 | 230 | 9 | 0.0146341463414634 | 80 |
| NBR1-206 | NBR1 | Q14596 | Next to BRCA1 gene 1 protein | chr17 | GO:0045668 | Not Cancer Driver | No | 88 | 0.0910973084886128 | 562 | 41 | 0.0424430641821946 | 0 |
| NOCT-201 | NOCT | Q9UK39 | Nocturnin | chr4 | GO:0045668 | Not Cancer Driver | No | 22 | 0.0510440835266821 | 90 | 2 | 0.0046403712296983 | 0 |
| NOG-201 | NOG | Q13253 | Noggin | chr17 | GO:0045668 | Not Cancer Driver | No | 15 | 0.0646551724137931 | 87 | 5 | 0.021551724137931 | 17 |
| NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0045668 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
| OSTN-202 | OSTN | P61366 | Osteocrin | chr3 | GO:0045668 | Not Cancer Driver | No | 26 | 0.1954887218045112 | 54 | 12 | 0.0902255639097744 | 0 |
| PPARG-201 | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0045668 | Census | Yes | 60 | 0.1188118811881188 | 44 | 3 | 0.0059405940594059 | 3 |
| PTCH1-201 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0045668 | Census, Compendium | Yes | 156 | 0.1078092605390463 | 383 | 39 | 0.0269523151347615 | 17 |
| RANBP3L-201 | RANBP3L | Q86VV4 | Ran-binding protein 3-like | chr5 | GO:0045668 | Not Cancer Driver | No | 47 | 0.1010752688172043 | 187 | 24 | 0.0516129032258064 | 0 |
| RIOX1-201 | RIOX1 | Q9H6W3 | Ribosomal oxygenase 1 | chr14 | GO:0045668 | Not Cancer Driver | No | 0 | 0.0 | 217 | 0 | 0.0 | 0 |
| RORB-202 | RORB | Q92753 | Nuclear receptor ROR-beta | chr9 | GO:0045668 | Not Cancer Driver | No | 75 | 0.1595744680851064 | 87 | 15 | 0.0319148936170212 | 1 |
| SEMA4D-208 | SEMA4D | Q92854 | Semaphorin-4D | chr9 | GO:0045668 | Not Cancer Driver | No | 93 | 0.1078886310904872 | 132 | 14 | 0.0162412993039443 | 0 |
| SFRP1-201 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0045668 | Not Cancer Driver | No | 31 | 0.0987261146496815 | 39 | 4 | 0.0127388535031847 | 0 |
| SKI-201 | SKI | P12755 | Ski oncogene | chr1 | GO:0045668 | Census | Yes | 41 | 0.0563186813186813 | 434 | 27 | 0.037087912087912 | 8 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0045668 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| SMAD6-201 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0045668 | Not Cancer Driver | No | 29 | 0.0584677419354838 | 249 | 4 | 0.0080645161290322 | 7 |
| SOX9-201 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0045668 | Compendium | Yes | 69 | 0.1355599214145383 | 497 | 66 | 0.1296660117878192 | 13 |
| SUFU-202 | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | GO:0045668 | Census | Yes | 48 | 0.0991735537190082 | 200 | 15 | 0.03099173553719 | 2 |
| TMEM53-202 | TMEM53 | Q6P2H8 | Transmembrane protein 53 | chr1 | GO:0045668 | Not Cancer Driver | No | 27 | 0.0974729241877256 | 14 | 0 | 0.0 | 0 |
| TMEM64-203 | TMEM64 | Q6YI46 | Transmembrane protein 64 | chr8 | GO:0045668 | Not Cancer Driver | No | 19 | 0.05 | 33 | 0 | 0.0 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0045668 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFAIP6-201 | TNFAIP6 | P98066 | Tumor necrosis factor-inducible gene 6 protein | chr2 | GO:0045668 | Not Cancer Driver | No | 48 | 0.1732851985559566 | 13 | 5 | 0.0180505415162454 | 0 |
| TNN-201 | TNN | Q9UQP3 | Tenascin-N | chr1 | GO:0045668 | Not Cancer Driver | No | 357 | 0.2748267898383372 | 642 | 199 | 0.153194765204003 | 0 |
| TOB1-202 | TOB1 | P50616 | Protein Tob1 | chr17 | GO:0045668 | Not Cancer Driver | No | 27 | 0.0782608695652174 | 214 | 15 | 0.0434782608695652 | 0 |
| TRPM4-201 | TRPM4 | Q8TD43 | Transient receptor potential cation channel subfamily M member 4 | chr19 | GO:0045668 | Not Cancer Driver | No | 124 | 0.1021416803953871 | 149 | 17 | 0.0140032948929159 | 12 |
| TWIST1-201 | TWIST1 | Q15672 | Twist-related protein 1 | chr7 | GO:0045668 | Not Cancer Driver | No | 21 | 0.1039603960396039 | 132 | 9 | 0.0445544554455445 | 6 |
| TWIST2-202 | TWIST2 | Q8WVJ9 | Twist-related protein 2 | chr2 | GO:0045668 | Not Cancer Driver | No | 9 | 0.05625 | 90 | 2 | 0.0125 | 3 |
| TWSG1-201 | TWSG1 | Q9GZX9 | Twisted gastrulation protein homolog 1 | chr18 | GO:0045668 | Not Cancer Driver | No | 20 | 0.0896860986547085 | 19 | 2 | 0.0089686098654708 | 0 |
| UCMA-201 | UCMA | Q8WVF2 | Unique cartilage matrix-associated protein | chr10 | GO:0045668 | Not Cancer Driver | No | 22 | 0.1594202898550724 | 96 | 14 | 0.1014492753623188 | 0 |
| VEGFC-202 | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0045668 | Not Cancer Driver | No | 104 | 0.2482100238663484 | 37 | 8 | 0.0190930787589498 | 0 |