Total number of protein in "GO:0045669" GO term: 68
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1-207 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0045669 | Census, Compendium | Yes | 71 | 0.1394891944990176 | 21 | 8 | 0.0157170923379174 | 6 |
| ACVR2A-201 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:0045669 | Census, Compendium | Yes | 64 | 0.124756335282651 | 56 | 4 | 0.0077972709551656 | 0 |
| ACVR2B-201 | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0045669 | Not Cancer Driver | No | 55 | 0.107421875 | 70 | 11 | 0.021484375 | 2 |
| ATRAID-201 | ATRAID | Q6UW56 | All-trans retinoic acid-induced differentiation factor | chr2 | GO:0045669 | Not Cancer Driver | No | 10 | 0.0436681222707423 | 9 | 2 | 0.0087336244541484 | 0 |
| BMP2-201 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0045669 | Not Cancer Driver | No | 54 | 0.1363636363636363 | 140 | 22 | 0.0555555555555555 | 0 |
| BMP4-201 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0045669 | Not Cancer Driver | No | 69 | 0.1691176470588235 | 142 | 20 | 0.0490196078431372 | 5 |
| BMP6-201 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0045669 | Not Cancer Driver | No | 79 | 0.1539961013645224 | 228 | 41 | 0.0799220272904483 | 6 |
| BMP7-201 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0045669 | Not Cancer Driver | No | 68 | 0.1577726218097447 | 69 | 13 | 0.0301624129930394 | 0 |
| BMPR1A-201 | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0045669 | Census, Compendium | Yes | 37 | 0.0695488721804511 | 21 | 0 | 0.0 | 8 |
| BMPR1B-208 | BMPR1B | O00238 | Bone morphogenetic protein receptor type-1B | chr4 | GO:0045669 | Not Cancer Driver | No | 55 | 0.1095617529880478 | 64 | 4 | 0.0079681274900398 | 4 |
| BMPR2-202 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0045669 | Compendium | Yes | 100 | 0.0963391136801541 | 601 | 49 | 0.0472061657032755 | 17 |
| CCN1-201 | CCN1 | O00622 | CCN family member 1 | chr1 | GO:0045669 | Not Cancer Driver | No | 29 | 0.0761154855643044 | 12 | 0 | 0.0 | 0 |
| CCN4-202 | CCN4 | O95388 | CCN family member 4 | chr8 | GO:0045669 | Not Cancer Driver | No | 84 | 0.2288828337874659 | 20 | 7 | 0.0190735694822888 | 0 |
| CEBPA-201 | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0045669 | Census, Compendium | Yes | 10 | 0.0279329608938547 | 343 | 10 | 0.0279329608938547 | 1 |
| CEBPB-201 | CEBPB | P17676 | CCAAT/enhancer-binding protein beta | chr20 | GO:0045669 | Not Cancer Driver | No | 2 | 0.0057971014492753 | 276 | 0 | 0.0 | 0 |
| CEBPD-201 | CEBPD | P49716 | CCAAT/enhancer-binding protein delta | chr8 | GO:0045669 | Not Cancer Driver | No | 5 | 0.0185873605947955 | 234 | 4 | 0.0148698884758364 | 0 |
| CLIC1-208 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | GO:0045669 | Not Cancer Driver | No | 28 | 0.1161825726141078 | 27 | 4 | 0.0165975103734439 | 0 |
| CTHRC1-201 | CTHRC1 | Q96CG8 | Collagen triple helix repeat-containing protein 1 | chr8 | GO:0045669 | Not Cancer Driver | No | 19 | 0.0781893004115226 | 62 | 6 | 0.0246913580246913 | 0 |
| CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0045669 | Census, Compendium | Yes | 363 | 0.4647887323943662 | 288 | 291 | 0.3725992317541613 | 11 |
| CTNNBIP1-203 | CTNNBIP1 | Q9NSA3 | Beta-catenin-interacting protein 1 | chr1 | GO:0045669 | Not Cancer Driver | No | 8 | 0.0987654320987654 | 64 | 7 | 0.0864197530864197 | 0 |
| DDR2-201 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | GO:0045669 | Census | Yes | 129 | 0.1508771929824561 | 120 | 25 | 0.0292397660818713 | 7 |
| DNAI3-201 | DNAI3 | Q8IWG1 | Dynein axonemal intermediate chain 3 | chr1 | GO:0045669 | Not Cancer Driver | No | 87 | 0.0976430976430976 | 212 | 20 | 0.0224466891133557 | 0 |
| FAM20C-201 | FAM20C | Q8IXL6 | Extracellular serine/threonine protein kinase FAM20C | chr7 | GO:0045669 | Not Cancer Driver | No | 21 | 0.035958904109589 | 188 | 1 | 0.0017123287671232 | 8 |
| FBN2-201 | FBN2 | P35556 | Fibrillin-2 | chr5 | GO:0045669 | Compendium | Yes | 476 | 0.1634615384615384 | 137 | 21 | 0.0072115384615384 | 27 |
| FBXO5-201 | FBXO5 | Q9UKT4 | F-box only protein 5 | chr6 | GO:0045669 | Not Cancer Driver | No | 29 | 0.0648769574944071 | 114 | 10 | 0.0223713646532438 | 0 |
| FERMT2-201 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0045669 | Not Cancer Driver | No | 44 | 0.0647058823529411 | 102 | 8 | 0.0117647058823529 | 0 |
| FFAR4-201 | FFAR4 | Q5NUL3 | Free fatty acid receptor 4 | chr10 | GO:0045669 | Not Cancer Driver | No | 36 | 0.0997229916897507 | 0 | 0 | 0.0 | 0 |
| FGF2-201 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0045669 | Not Cancer Driver | No | 17 | 0.0590277777777777 | 183 | 5 | 0.0173611111111111 | 0 |
| FZD1-201 | FZD1 | Q9UP38 | Frizzled-1 | chr7 | GO:0045669 | Not Cancer Driver | No | 65 | 0.1004636785162287 | 133 | 2 | 0.0030911901081916 | 0 |
| GDF10-201 | GDF10 | P55107 | Growth/differentiation factor 10 | chr10 | GO:0045669 | Not Cancer Driver | No | 81 | 0.1694560669456067 | 254 | 54 | 0.1129707112970711 | 0 |
| GDPD2-201 | GDPD2 | Q9HCC8 | Glycerophosphoinositol inositolphosphodiesterase GDPD2 | chrX | GO:0045669 | Not Cancer Driver | No | 67 | 0.12430426716141 | 43 | 11 | 0.0204081632653061 | 0 |
| GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0045669 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
| HGF-201 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0045669 | Compendium | Yes | 196 | 0.2692307692307692 | 43 | 16 | 0.0219780219780219 | 0 |
| IFITM1-202 | IFITM1 | P13164 | Interferon-induced transmembrane protein 1 | chr11 | GO:0045669 | Not Cancer Driver | No | 11 | 0.088 | 0 | 0 | 0.0 | 0 |
| IGF1-201 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0045669 | Not Cancer Driver | No | 30 | 0.1538461538461538 | 87 | 18 | 0.0923076923076923 | 0 |
| IL6-201 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0045669 | Not Cancer Driver | No | 32 | 0.1509433962264151 | 58 | 6 | 0.0283018867924528 | 0 |
| IL6R-202 | IL6R | P08887 | Interleukin-6 receptor subunit alpha | chr1 | GO:0045669 | Not Cancer Driver | No | 43 | 0.0918803418803418 | 166 | 19 | 0.0405982905982906 | 1 |
| IL6ST-204 | IL6ST | P40189 | Interleukin-6 receptor subunit beta | chr5 | GO:0045669 | Census, Compendium | Yes | 76 | 0.0827886710239651 | 315 | 26 | 0.0283224400871459 | 3 |
| ILK-201 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0045669 | Not Cancer Driver | No | 30 | 0.0663716814159292 | 72 | 7 | 0.0154867256637168 | 0 |
| JAG1-201 | JAG1 | P78504 | Protein jagged-1 | chr20 | GO:0045669 | Not Cancer Driver | No | 133 | 0.1091954022988505 | 172 | 14 | 0.0114942528735632 | 45 |
| JUND-201 | JUND | P17535 | Transcription factor JunD | chr19 | GO:0045669 | Not Cancer Driver | No | 18 | 0.0518731988472622 | 313 | 17 | 0.0489913544668587 | 0 |
| LRP3-201 | LRP3 | O75074 | Low-density lipoprotein receptor-related protein 3 | chr19 | GO:0045669 | Not Cancer Driver | No | 57 | 0.074025974025974 | 214 | 12 | 0.0155844155844155 | 0 |
| LRP5-201 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0045669 | Not Cancer Driver | No | 196 | 0.1213622291021671 | 189 | 24 | 0.014860681114551 | 54 |
| LTF-201 | LTF | P02788 | Lactotransferrin | chr3 | GO:0045669 | Not Cancer Driver | No | 90 | 0.1267605633802817 | 21 | 3 | 0.004225352112676 | 0 |
| MEF2C-209 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0045669 | Not Cancer Driver | No | 54 | 0.1141649048625792 | 408 | 51 | 0.1078224101479915 | 2 |
| MSX2-201 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0045669 | Not Cancer Driver | No | 21 | 0.0786516853932584 | 170 | 10 | 0.0374531835205992 | 3 |
| NELL1-203 | NELL1 | Q92832 | Protein kinase C-binding protein NELL1 | chr11 | GO:0045669 | Not Cancer Driver | No | 198 | 0.2444444444444444 | 7 | 1 | 0.0012345679012345 | 0 |
| NPNT-202 | NPNT | Q6UXI9 | Nephronectin | chr4 | GO:0045669 | Not Cancer Driver | No | 71 | 0.1256637168141593 | 218 | 26 | 0.0460176991150442 | 0 |
| NPPC-202 | NPPC | P23582 | C-type natriuretic peptide | chr2 | GO:0045669 | Not Cancer Driver | No | 8 | 0.0634920634920634 | 82 | 5 | 0.0396825396825396 | 0 |
| PPP3CA-203 | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0045669 | Compendium | Yes | 63 | 0.1209213051823416 | 140 | 24 | 0.0460652591170825 | 7 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0045669 | Census | Yes | 164 | 0.1798245614035087 | 190 | 31 | 0.0339912280701754 | 2 |
| RUNX2-212 | RUNX2 | Q13950 | Runt-related transcription factor 2 | chr6 | GO:0045669 | Not Cancer Driver | No | 50 | 0.0959692898272552 | 447 | 44 | 0.0844529750479846 | 30 |
| SCUBE3-201 | SCUBE3 | Q8IX30 | Signal peptide, CUB and EGF-like domain-containing protein 3 | chr6 | GO:0045669 | Not Cancer Driver | No | 89 | 0.0896273917421953 | 110 | 10 | 0.0100704934541792 | 2 |
| SFRP2-201 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0045669 | Not Cancer Driver | No | 37 | 0.1254237288135593 | 1 | 0 | 0.0 | 0 |
| SMAD1-201 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0045669 | Not Cancer Driver | No | 39 | 0.0838709677419354 | 162 | 19 | 0.0408602150537634 | 0 |
| SMAD5-211 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0045669 | Not Cancer Driver | No | 25 | 0.053763440860215 | 172 | 6 | 0.0129032258064516 | 0 |
| SOX11-201 | SOX11 | P35716 | Transcription factor SOX-11 | chr2 | GO:0045669 | Not Cancer Driver | No | 54 | 0.1224489795918367 | 370 | 47 | 0.1065759637188208 | 23 |
| SUCO-201 | SUCO | Q9UBS9 | SUN domain-containing ossification factor | chr1 | GO:0045669 | Not Cancer Driver | No | 114 | 0.0909090909090909 | 786 | 71 | 0.0566188197767145 | 0 |
| TENT5A-201 | TENT5A | Q96IP4 | Terminal nucleotidyltransferase 5A | chr6 | GO:0045669 | Not Cancer Driver | No | 33 | 0.0746606334841629 | 0 | 0 | 0.0 | 0 |
| TMEM119-201 | TMEM119 | Q4V9L6 | Transmembrane protein 119 | chr12 | GO:0045669 | Not Cancer Driver | No | 44 | 0.1554770318021201 | 195 | 35 | 0.1236749116607773 | 0 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0045669 | Census, Compendium | Yes | 198 | 0.2911764705882353 | 398 | 120 | 0.1764705882352941 | 21 |
| WNT10B-201 | WNT10B | O00744 | Protein Wnt-10b | chr12 | GO:0045669 | Not Cancer Driver | No | 45 | 0.1156812339331619 | 84 | 14 | 0.0359897172236503 | 2 |
| WNT3-201 | WNT3 | P56703 | Proto-oncogene Wnt-3 | chr17 | GO:0045669 | Not Cancer Driver | No | 44 | 0.1239436619718309 | 34 | 9 | 0.0253521126760563 | 0 |
| WNT4-201 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0045669 | Not Cancer Driver | No | 25 | 0.0712250712250712 | 39 | 2 | 0.0056980056980056 | 5 |
| WNT7B-201 | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0045669 | Not Cancer Driver | No | 41 | 0.1174785100286533 | 11 | 1 | 0.0028653295128939 | 0 |
| WWTR1-201 | WWTR1 | Q9GZV5 | WW domain-containing transcription regulator protein 1 | chr3 | GO:0045669 | Census | Yes | 29 | 0.0725 | 389 | 29 | 0.0725 | 0 |
| YAP1-201 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0045669 | Not Cancer Driver | No | 41 | 0.0813492063492063 | 491 | 41 | 0.0813492063492063 | 0 |
| ZHX3-221 | ZHX3 | Q9H4I2 | Zinc fingers and homeoboxes protein 3 | chr20 | GO:0045669 | Not Cancer Driver | No | 89 | 0.0930962343096234 | 617 | 61 | 0.0638075313807531 | 0 |