Total number of protein in "GO:0045732" GO term: 79
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMER1-201 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0045732 | Census, Compendium | Yes | 196 | 0.1726872246696035 | 1041 | 185 | 0.1629955947136563 | 0 |
| APC-201 | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0045732 | Census, Compendium | Yes | 295 | 0.1037636299683433 | 2412 | 248 | 0.0872317973971157 | 22 |
| APC2-206 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | GO:0045732 | Not Cancer Driver | No | 86 | 0.0373425966131133 | 1739 | 61 | 0.0264871906209292 | 0 |
| ASB11-203 | ASB11 | Q8WXH4 | Ankyrin repeat and SOCS box protein 11 | chrX | GO:0045732 | Not Cancer Driver | No | 32 | 0.0990712074303405 | 7 | 1 | 0.0030959752321981 | 0 |
| ASB5-201 | ASB5 | Q8WWX0 | Ankyrin repeat and SOCS box protein 5 | chr4 | GO:0045732 | Not Cancer Driver | No | 77 | 0.2340425531914893 | 7 | 4 | 0.0121580547112462 | 0 |
| ASB9-203 | ASB9 | Q96DX5 | Ankyrin repeat and SOCS box protein 9 | chrX | GO:0045732 | Not Cancer Driver | No | 47 | 0.1598639455782313 | 71 | 17 | 0.0578231292517006 | 0 |
| ATG7-226 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | GO:0045732 | Compendium | Yes | 60 | 0.0853485064011379 | 54 | 6 | 0.0085348506401137 | 6 |
| AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0045732 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
| BARD1-201 | BARD1 | Q99728 | BRCA1-associated RING domain protein 1 | chr2 | GO:0045732 | Census | Yes | 71 | 0.0913770913770913 | 390 | 39 | 0.0501930501930501 | 0 |
| C4BPA-201 | C4BPA | P04003 | C4b-binding protein alpha chain | chr1 | GO:0045732 | Not Cancer Driver | No | 90 | 0.1507537688442211 | 41 | 9 | 0.0150753768844221 | 0 |
| C4BPB-203 | C4BPB | P20851 | C4b-binding protein beta chain | chr1 | GO:0045732 | Not Cancer Driver | No | 26 | 0.1031746031746031 | 0 | 0 | 0.0 | 0 |
| CBLB-201 | CBLB | Q13191 | E3 ubiquitin-protein ligase CBL-B | chr3 | GO:0045732 | Census | Yes | 126 | 0.1283095723014256 | 565 | 77 | 0.0784114052953156 | 0 |
| CDKN1B-201 | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0045732 | Census, Compendium | Yes | 14 | 0.0707070707070707 | 199 | 14 | 0.0707070707070707 | 0 |
| CSNK2A1-201 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0045732 | Not Cancer Driver | No | 47 | 0.1202046035805626 | 75 | 6 | 0.0153452685421994 | 4 |
| CSNK2A3-201 | CSNK2A3 | Q8NEV1 | Casein kinase II subunit alpha 3 | chr11 | GO:0045732 | Not Cancer Driver | No | 47 | 0.1202046035805626 | 76 | 9 | 0.0230179028132992 | 0 |
| CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0045732 | Not Cancer Driver | No | 54 | 0.0711462450592885 | 102 | 2 | 0.0026350461133069 | 0 |
| CUL4B-231 | CUL4B | Q13620 | Cullin-4B | chrX | GO:0045732 | Not Cancer Driver | No | 83 | 0.0909090909090909 | 207 | 23 | 0.0251916757940854 | 2 |
| DAB2IP-203 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0045732 | Not Cancer Driver | No | 95 | 0.0798990748528175 | 682 | 49 | 0.04121110176619 | 0 |
| DACT1-201 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | GO:0045732 | Not Cancer Driver | No | 131 | 0.1566985645933014 | 604 | 104 | 0.124401913875598 | 1 |
| DAOA-202 | DAOA | P59103 | D-amino acid oxidase activator | chr13 | GO:0045732 | Not Cancer Driver | No | 32 | 0.2091503267973856 | 54 | 12 | 0.0784313725490196 | 0 |
| DCAF1-203 | DCAF1 | Q9Y4B6 | DDB1- and CUL4-associated factor 1 | chr3 | GO:0045732 | Not Cancer Driver | No | 66 | 0.0437956204379562 | 495 | 21 | 0.0139349701393497 | 0 |
| DDB1-201 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0045732 | Not Cancer Driver | No | 98 | 0.0859649122807017 | 50 | 8 | 0.0070175438596491 | 3 |
| DTL-201 | DTL | Q9NZJ0 | Denticleless protein homolog | chr1 | GO:0045732 | Not Cancer Driver | No | 53 | 0.0726027397260273 | 333 | 38 | 0.0520547945205479 | 0 |
| EGLN2-201 | EGLN2 | Q96KS0 | Prolyl hydroxylase EGLN2 | chr19 | GO:0045732 | Not Cancer Driver | No | 36 | 0.0884520884520884 | 204 | 9 | 0.0221130221130221 | 0 |
| EZR-202 | EZR | P15311 | Ezrin | chr6 | GO:0045732 | Census | Yes | 51 | 0.0870307167235494 | 296 | 26 | 0.0443686006825938 | 0 |
| FAF1-201 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:0045732 | Not Cancer Driver | No | 54 | 0.083076923076923 | 241 | 23 | 0.0353846153846153 | 0 |
| FBXL5-201 | FBXL5 | Q9UKA1 | F-box/LRR-repeat protein 5 | chr4 | GO:0045732 | Not Cancer Driver | No | 50 | 0.0723589001447178 | 71 | 4 | 0.0057887120115774 | 0 |
| FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0045732 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
| GGA1-203 | GGA1 | Q9UJY5 | ADP-ribosylation factor-binding protein GGA1 | chr22 | GO:0045732 | Not Cancer Driver | No | 57 | 0.0892018779342723 | 385 | 23 | 0.0359937402190923 | 0 |
| GGA3-201 | GGA3 | Q9NZ52 | ADP-ribosylation factor-binding protein GGA3 | chr17 | GO:0045732 | Not Cancer Driver | No | 51 | 0.0705394190871369 | 421 | 29 | 0.0401106500691562 | 0 |
| GPC3-201 | GPC3 | P51654 | Glypican-3 | chrX | GO:0045732 | Census | Yes | 55 | 0.0948275862068965 | 87 | 7 | 0.0120689655172413 | 1 |
| GSK3A-201 | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0045732 | Not Cancer Driver | No | 33 | 0.0683229813664596 | 180 | 5 | 0.010351966873706 | 0 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0045732 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HAMP-201 | HAMP | P81172 | Hepcidin | chr19 | GO:0045732 | Not Cancer Driver | No | 7 | 0.0833333333333333 | 4 | 0 | 0.0 | 4 |
| HSP90AA1-201 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0045732 | Census, Compendium | Yes | 44 | 0.0601092896174863 | 258 | 15 | 0.0204918032786885 | 0 |
| IDE-201 | IDE | P14735 | Insulin-degrading enzyme | chr10 | GO:0045732 | Not Cancer Driver | No | 65 | 0.0637880274779195 | 96 | 6 | 0.0058881256133464 | 0 |
| IER3-201 | IER3 | P46695 | Radiation-inducible immediate-early gene IEX-1 | chr6 | GO:0045732 | Not Cancer Driver | No | 4 | 0.0256410256410256 | 106 | 3 | 0.0192307692307692 | 0 |
| ITCH-201 | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0045732 | Not Cancer Driver | No | 75 | 0.0830564784053156 | 335 | 33 | 0.0365448504983388 | 0 |
| LPCAT1-201 | LPCAT1 | Q8NF37 | Lysophosphatidylcholine acyltransferase 1 | chr5 | GO:0045732 | Not Cancer Driver | No | 67 | 0.1254681647940075 | 66 | 7 | 0.0131086142322097 | 0 |
| MSN-201 | MSN | P26038 | Moesin | chrX | GO:0045732 | Census, Compendium | Yes | 78 | 0.1351819757365684 | 286 | 39 | 0.0675909878682842 | 1 |
| MYLIP-202 | MYLIP | Q8WY64 | E3 ubiquitin-protein ligase MYLIP | chr6 | GO:0045732 | Not Cancer Driver | No | 41 | 0.0921348314606741 | 11 | 2 | 0.0044943820224719 | 0 |
| NDFIP1-201 | NDFIP1 | Q9BT67 | NEDD4 family-interacting protein 1 | chr5 | GO:0045732 | Not Cancer Driver | No | 17 | 0.0769230769230769 | 45 | 3 | 0.0135746606334841 | 0 |
| NDUFA13-204 | NDUFA13 | Q9P0J0 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | chr19 | GO:0045732 | Not Cancer Driver | No | 27 | 0.1875 | 24 | 6 | 0.0416666666666666 | 1 |
| NEDD4-208 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0045732 | Not Cancer Driver | No | 99 | 0.0750568612585291 | 717 | 55 | 0.0416982562547384 | 0 |
| NEDD4L-205 | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | GO:0045732 | Not Cancer Driver | No | 99 | 0.1015384615384615 | 463 | 44 | 0.0451282051282051 | 4 |
| NKD1-201 | NKD1 | Q969G9 | Protein naked cuticle homolog 1 | chr16 | GO:0045732 | Not Cancer Driver | No | 61 | 0.1297872340425531 | 438 | 58 | 0.1234042553191489 | 0 |
| NSF-201 | NSF | P46459 | Vesicle-fusing ATPase | chr17 | GO:0045732 | Not Cancer Driver | No | 32 | 0.043010752688172 | 84 | 2 | 0.0026881720430107 | 2 |
| OAZ1-211 | OAZ1 | P54368 | Ornithine decarboxylase antizyme 1 | chr19 | GO:0045732 | Not Cancer Driver | No | 21 | 0.0921052631578947 | 111 | 11 | 0.0482456140350877 | 0 |
| OAZ2-201 | OAZ2 | O95190 | Ornithine decarboxylase antizyme 2 | chr15 | GO:0045732 | Not Cancer Driver | No | 8 | 0.0423280423280423 | 11 | 0 | 0.0 | 0 |
| OAZ3-202 | OAZ3 | Q9UMX2 | Ornithine decarboxylase antizyme 3 | chr1 | GO:0045732 | Not Cancer Driver | No | 22 | 0.0936170212765957 | 33 | 1 | 0.0042553191489361 | 0 |
| PLK2-201 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0045732 | Not Cancer Driver | No | 55 | 0.0802919708029197 | 180 | 18 | 0.0262773722627737 | 0 |
| PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0045732 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
| RAB7A-201 | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | GO:0045732 | Not Cancer Driver | No | 19 | 0.0917874396135265 | 11 | 0 | 0.0 | 4 |
| RBX1-201 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0045732 | Not Cancer Driver | No | 9 | 0.0833333333333333 | 18 | 1 | 0.0092592592592592 | 0 |
| RDX-219 | RDX | P35241 | Radixin | chr11 | GO:0045732 | Not Cancer Driver | No | 44 | 0.0754716981132075 | 298 | 23 | 0.039451114922813 | 1 |
| RHBDD3-201 | RHBDD3 | Q9Y3P4 | Rhomboid domain-containing protein 3 | chr22 | GO:0045732 | Not Cancer Driver | No | 19 | 0.0492227979274611 | 147 | 12 | 0.0310880829015544 | 0 |
| RILP-201 | RILP | Q96NA2 | Rab-interacting lysosomal protein | chr17 | GO:0045732 | Not Cancer Driver | No | 24 | 0.0598503740648379 | 333 | 16 | 0.0399002493765586 | 0 |
| RNF41-201 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0045732 | Not Cancer Driver | No | 36 | 0.113564668769716 | 33 | 2 | 0.0063091482649842 | 0 |
| SEC22B-201 | SEC22B | O75396 | Vesicle-trafficking protein SEC22b | chr1 | GO:0045732 | Not Cancer Driver | No | 0 | 0.0 | 21 | 0 | 0.0 | 0 |
| SGSM3-201 | SGSM3 | Q96HU1 | Small G protein signaling modulator 3 | chr22 | GO:0045732 | Not Cancer Driver | No | 59 | 0.0787716955941255 | 77 | 7 | 0.0093457943925233 | 0 |
| SNF8-202 | SNF8 | Q96H20 | Vacuolar-sorting protein SNF8 | chr17 | GO:0045732 | Not Cancer Driver | No | 20 | 0.0775193798449612 | 10 | 1 | 0.003875968992248 | 0 |
| SORL1-201 | SORL1 | Q92673 | Sortilin-related receptor | chr11 | GO:0045732 | Not Cancer Driver | No | 298 | 0.1345980126467931 | 87 | 8 | 0.003613369467028 | 0 |
| SOX17-201 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | GO:0045732 | Compendium | Yes | 64 | 0.1545893719806763 | 379 | 45 | 0.108695652173913 | 2 |
| SOX9-201 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0045732 | Compendium | Yes | 69 | 0.1355599214145383 | 497 | 66 | 0.1296660117878192 | 13 |
| STX5-201 | STX5 | Q13190 | Syntaxin-5 | chr11 | GO:0045732 | Not Cancer Driver | No | 25 | 0.0704225352112676 | 148 | 7 | 0.0197183098591549 | 0 |
| TIPARP-201 | TIPARP | Q7Z3E1 | Protein mono-ADP-ribosyltransferase TIPARP | chr3 | GO:0045732 | Not Cancer Driver | No | 44 | 0.0669710806697108 | 202 | 16 | 0.0243531202435312 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0045732 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFAIP3-206 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0045732 | Census, Compendium | Yes | 69 | 0.0873417721518987 | 231 | 21 | 0.0265822784810126 | 1 |
| TNFSF12-201 | TNFSF12 | O43508 | Tumor necrosis factor ligand superfamily member 12 | chr17 | GO:0045732 | Not Cancer Driver | No | 6 | 0.0240963855421686 | 109 | 3 | 0.0120481927710843 | 0 |
| TRIM32-203 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0045732 | Not Cancer Driver | No | 62 | 0.0949464012251148 | 87 | 9 | 0.0137825421133231 | 3 |
| UBR3-201 | UBR3 | Q6ZT12 | E3 ubiquitin-protein ligase UBR3 | chr2 | GO:0045732 | Not Cancer Driver | No | 110 | 0.0582627118644067 | 339 | 23 | 0.0121822033898305 | 0 |
| UBXN2A-201 | UBXN2A | P68543 | UBX domain-containing protein 2A | chr2 | GO:0045732 | Not Cancer Driver | No | 25 | 0.0965250965250965 | 58 | 7 | 0.027027027027027 | 0 |
| VCP-201 | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0045732 | Not Cancer Driver | No | 74 | 0.0918114143920595 | 186 | 14 | 0.0173697270471464 | 12 |
| VGLL4-211 | VGLL4 | Q14135 | Transcription cofactor vestigial-like protein 4 | chr3 | GO:0045732 | Not Cancer Driver | No | 26 | 0.0878378378378378 | 250 | 22 | 0.0743243243243243 | 0 |
| VIP-202 | VIP | P01282 | VIP peptides | chr6 | GO:0045732 | Not Cancer Driver | No | 52 | 0.3058823529411765 | 78 | 22 | 0.1294117647058823 | 0 |
| VPS11-207 | VPS11 | Q9H270 | Vacuolar protein sorting-associated protein 11 homolog | chr11 | GO:0045732 | Not Cancer Driver | No | 76 | 0.0807651434643995 | 118 | 4 | 0.004250797024442 | 1 |
| VPS28-201 | VPS28 | Q9UK41 | Vacuolar protein sorting-associated protein 28 homolog | chr8 | GO:0045732 | Not Cancer Driver | No | 17 | 0.0769230769230769 | 31 | 5 | 0.0226244343891402 | 0 |
| VPS35-201 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | GO:0045732 | Not Cancer Driver | No | 55 | 0.0690954773869346 | 99 | 7 | 0.0087939698492462 | 1 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0045732 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |