Total number of protein in "GO:0045931" GO term: 32
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0045931 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0045931 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
ASNS-202 | ASNS | P08243 | Asparagine synthetase [glutamine-hydrolyzing] | chr7 | GO:0045931 | Not Cancer Driver | No | 58 | 0.1033868092691622 | 11 | 0 | 0.0 | 3 |
AURKA-208 | AURKA | O14965 | Aurora kinase A | chr20 | GO:0045931 | Not Cancer Driver | No | 25 | 0.0620347394540942 | 180 | 17 | 0.0421836228287841 | 0 |
BRCA2-201 | BRCA2 | P51587 | Breast cancer type 2 susceptibility protein | chr13 | GO:0045931 | Census, Compendium | Yes | 310 | 0.0906963136337039 | 1545 | 152 | 0.0444704505558806 | 46 |
CCDC57-202 | CCDC57 | Q2TAC2 | Coiled-coil domain-containing protein 57 | chr17 | GO:0045931 | Not Cancer Driver | No | 79 | 0.0863387978142076 | 604 | 44 | 0.048087431693989 | 0 |
CCNB1-201 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | GO:0045931 | Not Cancer Driver | No | 30 | 0.069284064665127 | 146 | 10 | 0.023094688221709 | 0 |
CDC25B-201 | CDC25B | P30305 | M-phase inducer phosphatase 2 | chr20 | GO:0045931 | Not Cancer Driver | No | 61 | 0.1051724137931034 | 329 | 33 | 0.0568965517241379 | 0 |
DUSP3-201 | DUSP3 | P51452 | Dual specificity protein phosphatase 3 | chr17 | GO:0045931 | Not Cancer Driver | No | 14 | 0.0756756756756756 | 4 | 0 | 0.0 | 0 |
DYNLT3-201 | DYNLT3 | P51808 | Dynein light chain Tctex-type 3 | chrX | GO:0045931 | Not Cancer Driver | No | 8 | 0.0689655172413793 | 0 | 0 | 0.0 | 0 |
EIF4E-203 | EIF4E | P06730 | Eukaryotic translation initiation factor 4E | chr4 | GO:0045931 | Not Cancer Driver | No | 18 | 0.0829493087557603 | 54 | 4 | 0.0184331797235023 | 0 |
EIF4EBP1-201 | EIF4EBP1 | Q13541 | Eukaryotic translation initiation factor 4E-binding protein 1 | chr8 | GO:0045931 | Not Cancer Driver | No | 8 | 0.0677966101694915 | 118 | 8 | 0.0677966101694915 | 0 |
FOXA1-201 | FOXA1 | P55317 | Hepatocyte nuclear factor 3-alpha | chr14 | GO:0045931 | Census, Compendium | Yes | 85 | 0.1800847457627118 | 295 | 44 | 0.0932203389830508 | 0 |
HSF1-204 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0045931 | Not Cancer Driver | No | 49 | 0.0926275992438563 | 336 | 30 | 0.0567107750472589 | 0 |
LGMN-201 | LGMN | Q99538 | Legumain | chr14 | GO:0045931 | Not Cancer Driver | No | 40 | 0.092378752886836 | 112 | 11 | 0.0254041570438799 | 0 |
MDM2-224 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0045931 | Census, Compendium | Yes | 39 | 0.0794297352342158 | 298 | 24 | 0.0488798370672097 | 0 |
MEIS2-221 | MEIS2 | O14770 | Homeobox protein Meis2 | chr15 | GO:0045931 | Not Cancer Driver | No | 78 | 0.1635220125786163 | 358 | 66 | 0.1383647798742138 | 0 |
NKX3-1-201 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0045931 | Not Cancer Driver | No | 26 | 0.1111111111111111 | 175 | 12 | 0.0512820512820512 | 0 |
PAFAH1B1-202 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0045931 | Not Cancer Driver | No | 37 | 0.0902439024390243 | 83 | 11 | 0.0268292682926829 | 7 |
PKN2-203 | PKN2 | Q16513 | Serine/threonine-protein kinase N2 | chr1 | GO:0045931 | Not Cancer Driver | No | 76 | 0.0772357723577235 | 415 | 29 | 0.0294715447154471 | 0 |
POLDIP2-201 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | GO:0045931 | Not Cancer Driver | No | 27 | 0.0733695652173913 | 95 | 8 | 0.0217391304347826 | 0 |
PRKCA-202 | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0045931 | Not Cancer Driver | No | 70 | 0.1041666666666666 | 155 | 17 | 0.025297619047619 | 0 |
PTPN11-201 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0045931 | Census, Compendium | Yes | 92 | 0.1551433389544688 | 260 | 27 | 0.0455311973018549 | 44 |
RPS6KB1-201 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0045931 | Not Cancer Driver | No | 36 | 0.0685714285714285 | 226 | 22 | 0.0419047619047619 | 0 |
SHB-201 | SHB | Q15464 | SH2 domain-containing adapter protein B | chr9 | GO:0045931 | Not Cancer Driver | No | 42 | 0.0825147347740668 | 338 | 29 | 0.0569744597249508 | 0 |
SMOC2-202 | SMOC2 | Q9H3U7 | SPARC-related modular calcium-binding protein 2 | chr6 | GO:0045931 | Not Cancer Driver | No | 64 | 0.1434977578475336 | 217 | 39 | 0.0874439461883408 | 0 |
SPHK1-210 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0045931 | Not Cancer Driver | No | 29 | 0.0755208333333333 | 25 | 0 | 0.0 | 0 |
STAT5B-201 | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0045931 | Census, Compendium | Yes | 73 | 0.0927573062261753 | 145 | 17 | 0.0216010165184243 | 5 |
TAL1-206 | TAL1 | P17542 | T-cell acute lymphocytic leukemia protein 1 | chr1 | GO:0045931 | Census | Yes | 48 | 0.1450151057401812 | 305 | 47 | 0.1419939577039275 | 0 |
TTL-201 | TTL | Q8NG68 | Tubulin--tyrosine ligase | chr2 | GO:0045931 | Not Cancer Driver | No | 29 | 0.0769230769230769 | 24 | 1 | 0.0026525198938992 | 0 |
USP2-201 | USP2 | O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | chr11 | GO:0045931 | Not Cancer Driver | No | 65 | 0.1074380165289256 | 214 | 28 | 0.0462809917355371 | 0 |
USP22-201 | USP22 | Q9UPT9 | Ubiquitin carboxyl-terminal hydrolase 22 | chr17 | GO:0045931 | Not Cancer Driver | No | 42 | 0.08 | 50 | 1 | 0.0019047619047619 | 0 |