Total number of protein in "GO:0046330" GO term: 96
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGER-206 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0046330 | Not Cancer Driver | No | 17 | 0.042079207920792 | 297 | 12 | 0.0297029702970297 | 0 |
| ANKRD6-201 | ANKRD6 | Q9Y2G4 | Ankyrin repeat domain-containing protein 6 | chr6 | GO:0046330 | Not Cancer Driver | No | 69 | 0.0949105914718019 | 504 | 46 | 0.0632737276478679 | 0 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0046330 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
| AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0046330 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
| BIRC7-201 | BIRC7 | Q96CA5 | Baculoviral IAP repeat-containing protein 7 | chr20 | GO:0046330 | Not Cancer Driver | No | 45 | 0.1510067114093959 | 138 | 18 | 0.0604026845637583 | 0 |
| CARD9-201 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | GO:0046330 | Not Cancer Driver | No | 54 | 0.1007462686567164 | 225 | 26 | 0.0485074626865671 | 10 |
| CCL19-201 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0046330 | Not Cancer Driver | No | 5 | 0.0510204081632653 | 7 | 0 | 0.0 | 0 |
| CCL21-201 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0046330 | Not Cancer Driver | No | 12 | 0.0895522388059701 | 59 | 5 | 0.0373134328358208 | 0 |
| CCN2-201 | CCN2 | P29279 | CCN family member 2 | chr6 | GO:0046330 | Not Cancer Driver | No | 37 | 0.1060171919770773 | 0 | 0 | 0.0 | 0 |
| CCR7-201 | CCR7 | P32248 | C-C chemokine receptor type 7 | chr17 | GO:0046330 | Census, Compendium | Yes | 42 | 0.1111111111111111 | 0 | 0 | 0.0 | 0 |
| CD27-201 | CD27 | P26842 | CD27 antigen | chr12 | GO:0046330 | Not Cancer Driver | No | 24 | 0.0923076923076923 | 92 | 10 | 0.0384615384615384 | 1 |
| CDC42-208 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0046330 | Not Cancer Driver | No | 21 | 0.1099476439790576 | 23 | 1 | 0.0052356020942408 | 1 |
| CRK-201 | CRK | P46108 | Adapter molecule crk | chr17 | GO:0046330 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 197 | 19 | 0.0625 | 0 |
| DAB2IP-203 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0046330 | Not Cancer Driver | No | 95 | 0.0798990748528175 | 682 | 49 | 0.04121110176619 | 0 |
| DKK1-201 | DKK1 | O94907 | Dickkopf-related protein 1 | chr10 | GO:0046330 | Not Cancer Driver | No | 48 | 0.1804511278195488 | 48 | 8 | 0.0300751879699248 | 0 |
| DUSP19-202 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0046330 | Not Cancer Driver | No | 18 | 0.0829493087557603 | 15 | 2 | 0.0092165898617511 | 0 |
| DUSP22-201 | DUSP22 | Q9NRW4 | Dual specificity protein phosphatase 22 | chr6 | GO:0046330 | Not Cancer Driver | No | 76 | 0.4130434782608695 | 0 | 0 | 0.0 | 0 |
| DVL2-201 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0046330 | Not Cancer Driver | No | 72 | 0.0978260869565217 | 515 | 52 | 0.0706521739130434 | 0 |
| DVL3-201 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0046330 | Not Cancer Driver | No | 58 | 0.0810055865921787 | 437 | 31 | 0.0432960893854748 | 0 |
| EDA2R-202 | EDA2R | Q9HAV5 | Tumor necrosis factor receptor superfamily member 27 | chrX | GO:0046330 | Not Cancer Driver | No | 41 | 0.138047138047138 | 72 | 7 | 0.0235690235690235 | 0 |
| EDAR-201 | EDAR | Q9UNE0 | Tumor necrosis factor receptor superfamily member EDAR | chr2 | GO:0046330 | Not Cancer Driver | No | 65 | 0.1450892857142857 | 117 | 16 | 0.0357142857142857 | 17 |
| ENST00000695856 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0046330 | Not Cancer Driver | No | 21 | 0.1099476439790576 | 23 | 1 | 0.0052356020942408 | 1 |
| F2RL1-201 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0046330 | Not Cancer Driver | No | 33 | 0.0831234256926952 | 7 | 0 | 0.0 | 0 |
| FCGR2B-202 | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0046330 | Census | Yes | 38 | 0.1225806451612903 | 100 | 23 | 0.0741935483870967 | 0 |
| FGF19-201 | FGF19 | O95750 | Fibroblast growth factor 19 | chr11 | GO:0046330 | Not Cancer Driver | No | 18 | 0.0833333333333333 | 36 | 5 | 0.0231481481481481 | 0 |
| FLT4-201 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0046330 | Census, Compendium | Yes | 203 | 0.1489361702127659 | 259 | 33 | 0.0242112986060161 | 14 |
| FZD10-201 | FZD10 | Q9ULW2 | Frizzled-10 | chr12 | GO:0046330 | Not Cancer Driver | No | 111 | 0.1910499139414802 | 65 | 13 | 0.0223752151462994 | 0 |
| FZD7-201 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0046330 | Not Cancer Driver | No | 72 | 0.1254355400696864 | 22 | 1 | 0.0017421602787456 | 0 |
| GADD45A-202 | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0046330 | Not Cancer Driver | No | 8 | 0.0484848484848484 | 40 | 4 | 0.0242424242424242 | 0 |
| GADD45B-201 | GADD45B | O75293 | Growth arrest and DNA damage-inducible protein GADD45 beta | chr19 | GO:0046330 | Not Cancer Driver | No | 8 | 0.05 | 14 | 0 | 0.0 | 0 |
| GADD45G-201 | GADD45G | O95257 | Growth arrest and DNA damage-inducible protein GADD45 gamma | chr9 | GO:0046330 | Not Cancer Driver | No | 10 | 0.0628930817610062 | 21 | 3 | 0.0188679245283018 | 0 |
| HIPK2-202 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0046330 | Not Cancer Driver | No | 124 | 0.1035058430717863 | 686 | 76 | 0.0634390651085141 | 0 |
| HMGB1-203 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0046330 | Not Cancer Driver | No | 10 | 0.0465116279069767 | 202 | 7 | 0.0325581395348837 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | GO:0046330 | Census, Compendium | Yes | 129 | 0.6825396825396826 | 16 | 2 | 0.0105820105820105 | 10 |
| IL1A-201 | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0046330 | Not Cancer Driver | No | 23 | 0.084870848708487 | 35 | 6 | 0.022140221402214 | 0 |
| IL1B-201 | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0046330 | Not Cancer Driver | No | 32 | 0.1189591078066914 | 16 | 2 | 0.0074349442379182 | 0 |
| LTBR-201 | LTBR | P36941 | Tumor necrosis factor receptor superfamily member 3 | chr12 | GO:0046330 | Not Cancer Driver | No | 31 | 0.0712643678160919 | 202 | 16 | 0.0367816091954023 | 0 |
| MAP2K4-201 | MAP2K4 | P45985 | Dual specificity mitogen-activated protein kinase kinase 4 | chr17 | GO:0046330 | Census, Compendium | Yes | 72 | 0.1804511278195488 | 137 | 23 | 0.0576441102756892 | 0 |
| MAP2K7-201 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0046330 | Compendium | Yes | 78 | 0.1861575178997613 | 145 | 17 | 0.0405727923627685 | 0 |
| MAP3K10-201 | MAP3K10 | Q02779 | Mitogen-activated protein kinase kinase kinase 10 | chr19 | GO:0046330 | Not Cancer Driver | No | 84 | 0.0880503144654088 | 591 | 45 | 0.0471698113207547 | 0 |
| MAP3K11-201 | MAP3K11 | Q16584 | Mitogen-activated protein kinase kinase kinase 11 | chr11 | GO:0046330 | Not Cancer Driver | No | 84 | 0.0991735537190082 | 466 | 50 | 0.0590318772136954 | 0 |
| MAP3K5-201 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0046330 | Not Cancer Driver | No | 146 | 0.106259097525473 | 244 | 23 | 0.0167394468704512 | 0 |
| MAP4K2-201 | MAP4K2 | Q12851 | Mitogen-activated protein kinase kinase kinase kinase 2 | chr11 | GO:0046330 | Not Cancer Driver | No | 59 | 0.0719512195121951 | 243 | 16 | 0.0195121951219512 | 0 |
| MAPK8IP1-201 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0046330 | Not Cancer Driver | No | 68 | 0.0956399437412095 | 444 | 39 | 0.0548523206751054 | 1 |
| MAPK8IP3-201 | MAPK8IP3 | Q9UPT6 | C-Jun-amino-terminal kinase-interacting protein 3 | chr16 | GO:0046330 | Not Cancer Driver | No | 142 | 0.1062874251497006 | 746 | 87 | 0.0651197604790419 | 3 |
| MAPKBP1-201 | MAPKBP1 | O60336 | Mitogen-activated protein kinase-binding protein 1 | chr15 | GO:0046330 | Not Cancer Driver | No | 128 | 0.0845442536327609 | 786 | 58 | 0.0383091149273447 | 0 |
| MBIP-203 | MBIP | Q9NS73 | MAP3K12-binding inhibitory protein 1 | chr14 | GO:0046330 | Not Cancer Driver | No | 30 | 0.0872093023255814 | 192 | 13 | 0.0377906976744186 | 0 |
| MFHAS1-201 | MFHAS1 | Q9Y4C4 | Malignant fibrous histiocytoma-amplified sequence 1 | chr8 | GO:0046330 | Not Cancer Driver | No | 72 | 0.0684410646387832 | 98 | 8 | 0.0076045627376425 | 0 |
| MINK1-202 | MINK1 | Q8N4C8 | Misshapen-like kinase 1 | chr17 | GO:0046330 | Not Cancer Driver | No | 86 | 0.0645645645645645 | 742 | 42 | 0.0315315315315315 | 0 |
| MTURN-201 | MTURN | Q8N3F0 | Maturin | chr7 | GO:0046330 | Not Cancer Driver | No | 9 | 0.0687022900763358 | 27 | 3 | 0.0229007633587786 | 0 |
| MYD88-209 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0046330 | Census, Compendium | Yes | 29 | 0.0979729729729729 | 47 | 2 | 0.0067567567567567 | 2 |
| MYOC-201 | MYOC | Q99972 | Myocilin | chr1 | GO:0046330 | Not Cancer Driver | No | 76 | 0.1507936507936507 | 197 | 36 | 0.0714285714285714 | 49 |
| NAIP-208 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0046330 | Not Cancer Driver | No | 29 | 0.0206699928724162 | 67 | 4 | 0.0028510334996436 | 0 |
| NCF1-201 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0046330 | Not Cancer Driver | No | 31 | 0.0794871794871794 | 181 | 11 | 0.0282051282051282 | 1 |
| NOD1-201 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0046330 | Not Cancer Driver | No | 98 | 0.1028331584470094 | 39 | 4 | 0.0041972717733473 | 0 |
| NOD2-201 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0046330 | Not Cancer Driver | No | 130 | 0.125 | 41 | 3 | 0.0028846153846153 | 15 |
| NOX1-204 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:0046330 | Not Cancer Driver | No | 76 | 0.1347517730496454 | 18 | 5 | 0.0088652482269503 | 0 |
| NRK-201 | NRK | Q7Z2Y5 | Nik-related protein kinase | chrX | GO:0046330 | Compendium | Yes | 253 | 0.1599241466498103 | 814 | 125 | 0.0790139064475347 | 0 |
| PJA2-201 | PJA2 | O43164 | E3 ubiquitin-protein ligase Praja-2 | chr5 | GO:0046330 | Not Cancer Driver | No | 60 | 0.0847457627118644 | 601 | 50 | 0.0706214689265536 | 0 |
| PLCB1-201 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0046330 | Not Cancer Driver | No | 264 | 0.2171052631578947 | 484 | 85 | 0.0699013157894736 | 0 |
| PTK2B-201 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0046330 | Not Cancer Driver | No | 117 | 0.1159563924677899 | 263 | 23 | 0.0227948463825569 | 0 |
| PYCARD-201 | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0046330 | Not Cancer Driver | No | 12 | 0.0615384615384615 | 39 | 4 | 0.0205128205128205 | 0 |
| RASGRP1-201 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0046330 | Not Cancer Driver | No | 70 | 0.0878293601003764 | 192 | 11 | 0.013801756587202 | 1 |
| RASSF2-202 | RASSF2 | P50749 | Ras association domain-containing protein 2 | chr20 | GO:0046330 | Not Cancer Driver | No | 70 | 0.2147239263803681 | 127 | 38 | 0.1165644171779141 | 0 |
| RB1CC1-201 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:0046330 | Not Cancer Driver | No | 150 | 0.0941028858218318 | 579 | 56 | 0.0351317440401505 | 0 |
| RIPK1-201 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0046330 | Compendium | Yes | 59 | 0.0879284649776453 | 277 | 28 | 0.0417287630402384 | 1 |
| RIPK2-201 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0046330 | Not Cancer Driver | No | 43 | 0.0796296296296296 | 143 | 14 | 0.0259259259259259 | 0 |
| SDCBP-201 | SDCBP | O00560 | Syntenin-1 | chr8 | GO:0046330 | Not Cancer Driver | No | 23 | 0.0771812080536912 | 17 | 1 | 0.0033557046979865 | 0 |
| SEMA3A-201 | SEMA3A | Q14563 | Semaphorin-3A | chr7 | GO:0046330 | Not Cancer Driver | No | 155 | 0.2010376134889753 | 165 | 38 | 0.0492866407263294 | 10 |
| SERPINF2-204 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0046330 | Not Cancer Driver | No | 46 | 0.0936863543788187 | 113 | 14 | 0.0285132382892057 | 1 |
| SH3RF1-201 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0046330 | Not Cancer Driver | No | 83 | 0.0934684684684684 | 588 | 55 | 0.0619369369369369 | 0 |
| SH3RF2-201 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0046330 | Not Cancer Driver | No | 125 | 0.1714677640603566 | 460 | 80 | 0.1097393689986282 | 0 |
| SH3RF3-201 | SH3RF3 | Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 | chr2 | GO:0046330 | Not Cancer Driver | No | 78 | 0.0884353741496598 | 566 | 45 | 0.0510204081632653 | 0 |
| SLAMF1-201 | SLAMF1 | Q13291 | Signaling lymphocytic activation molecule | chr1 | GO:0046330 | Not Cancer Driver | No | 54 | 0.1611940298507462 | 64 | 8 | 0.0238805970149253 | 0 |
| STK3-201 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:0046330 | Not Cancer Driver | No | 48 | 0.0977596741344195 | 241 | 22 | 0.0448065173116089 | 0 |
| TAOK1-201 | TAOK1 | Q7L7X3 | Serine/threonine-protein kinase TAO1 | chr17 | GO:0046330 | Not Cancer Driver | No | 94 | 0.0939060939060939 | 602 | 48 | 0.0479520479520479 | 7 |
| TAOK2-202 | TAOK2 | Q9UL54 | Serine/threonine-protein kinase TAO2 | chr16 | GO:0046330 | Not Cancer Driver | No | 129 | 0.1044534412955465 | 668 | 68 | 0.0550607287449392 | 0 |
| TAOK3-201 | TAOK3 | Q9H2K8 | Serine/threonine-protein kinase TAO3 | chr12 | GO:0046330 | Not Cancer Driver | No | 95 | 0.1057906458797327 | 494 | 51 | 0.0567928730512249 | 0 |
| TIRAP-202 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0046330 | Not Cancer Driver | No | 14 | 0.0633484162895927 | 80 | 5 | 0.0226244343891402 | 0 |
| TLR3-201 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0046330 | Not Cancer Driver | No | 89 | 0.0984513274336283 | 0 | 0 | 0.0 | 1 |
| TLR4-201 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0046330 | Not Cancer Driver | No | 253 | 0.301549463647199 | 0 | 0 | 0.0 | 0 |
| TLR9-201 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0046330 | Not Cancer Driver | No | 107 | 0.1036821705426356 | 35 | 3 | 0.002906976744186 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0046330 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFRSF19-202 | TNFRSF19 | Q9NS68 | Tumor necrosis factor receptor superfamily member 19 | chr13 | GO:0046330 | Not Cancer Driver | No | 52 | 0.1229314420803782 | 103 | 12 | 0.0283687943262411 | 0 |
| TNFSF11-202 | TNFSF11 | O14788 | Tumor necrosis factor ligand superfamily member 11 | chr13 | GO:0046330 | Not Cancer Driver | No | 32 | 0.1009463722397476 | 57 | 0 | 0.0 | 1 |
| TNIK-204 | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | GO:0046330 | Not Cancer Driver | No | 126 | 0.0926470588235294 | 782 | 86 | 0.063235294117647 | 0 |
| TPD52L1-213 | TPD52L1 | Q16890 | Tumor protein D53 | chr6 | GO:0046330 | Not Cancer Driver | No | 33 | 0.1617647058823529 | 170 | 26 | 0.1274509803921568 | 0 |
| TRAF4-201 | TRAF4 | Q9BUZ4 | TNF receptor-associated factor 4 | chr17 | GO:0046330 | Not Cancer Driver | No | 33 | 0.0702127659574468 | 27 | 1 | 0.002127659574468 | 0 |
| TRPV4-201 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0046330 | Not Cancer Driver | No | 109 | 0.1251435132032147 | 232 | 30 | 0.0344431687715269 | 38 |
| UNC5CL-201 | UNC5CL | Q8IV45 | UNC5C-like protein | chr6 | GO:0046330 | Not Cancer Driver | No | 54 | 0.1042471042471042 | 70 | 10 | 0.0193050193050193 | 0 |
| WNT16-201 | WNT16 | Q9UBV4 | Protein Wnt-16 | chr7 | GO:0046330 | Not Cancer Driver | No | 37 | 0.1013698630136986 | 29 | 5 | 0.0136986301369863 | 0 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0046330 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |
| WNT7A-201 | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0046330 | Not Cancer Driver | No | 68 | 0.1948424068767908 | 18 | 6 | 0.0171919770773638 | 4 |
| WNT7B-201 | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0046330 | Not Cancer Driver | No | 41 | 0.1174785100286533 | 11 | 1 | 0.0028653295128939 | 0 |
| XIAP-202 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0046330 | Not Cancer Driver | No | 61 | 0.1227364185110664 | 55 | 2 | 0.0040241448692152 | 0 |
| ZNF622-201 | ZNF622 | Q969S3 | Cytoplasmic 60S subunit biogenesis factor ZNF622 | chr5 | GO:0046330 | Not Cancer Driver | No | 52 | 0.1090146750524109 | 220 | 25 | 0.0524109014675052 | 0 |