Total number of protein in "GO:0048009" GO term: 32
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0048009 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AR-201 | AR | P10275 | Androgen receptor | chrX | GO:0048009 | Census, Compendium | Yes | 116 | 0.1260869565217391 | 443 | 38 | 0.0413043478260869 | 144 |
| COL6A1-201 | COL6A1 | P12109 | Collagen alpha-1(VI) chain | chr21 | GO:0048009 | Not Cancer Driver | No | 68 | 0.0661478599221789 | 436 | 23 | 0.0223735408560311 | 12 |
| CRIM1-201 | CRIM1 | Q9NZV1 | Cysteine-rich motor neuron 1 protein | chr2 | GO:0048009 | Not Cancer Driver | No | 106 | 0.1023166023166023 | 35 | 4 | 0.0038610038610038 | 0 |
| EIF2AK3-201 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0048009 | Not Cancer Driver | No | 102 | 0.0913978494623656 | 411 | 37 | 0.0331541218637992 | 1 |
| ERCC1-202 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0048009 | Not Cancer Driver | No | 36 | 0.1212121212121212 | 107 | 14 | 0.0471380471380471 | 1 |
| ERCC2-204 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0048009 | Census, Compendium | Yes | 103 | 0.1355263157894737 | 5 | 0 | 0.0 | 30 |
| GHR-201 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0048009 | Not Cancer Driver | No | 139 | 0.2178683385579937 | 229 | 59 | 0.0924764890282131 | 19 |
| GHSR-201 | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0048009 | Not Cancer Driver | No | 60 | 0.1639344262295081 | 4 | 0 | 0.0 | 2 |
| GIGYF1-207 | GIGYF1 | O75420 | GRB10-interacting GYF protein 1 | chr7 | GO:0048009 | Not Cancer Driver | No | 111 | 0.1072463768115942 | 860 | 94 | 0.0908212560386473 | 0 |
| GIGYF2-201 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:0048009 | Not Cancer Driver | No | 73 | 0.0561970746728252 | 1098 | 62 | 0.0477290223248652 | 6 |
| GRB10-205 | GRB10 | Q13322 | Growth factor receptor-bound protein 10 | chr7 | GO:0048009 | Not Cancer Driver | No | 67 | 0.1127946127946128 | 222 | 30 | 0.0505050505050505 | 0 |
| GRB2-202 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0048009 | Not Cancer Driver | No | 21 | 0.0967741935483871 | 10 | 0 | 0.0 | 0 |
| IGF1-201 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0048009 | Not Cancer Driver | No | 30 | 0.1538461538461538 | 87 | 18 | 0.0923076923076923 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0048009 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| IGF2-205 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0048009 | Not Cancer Driver | No | 32 | 0.1777777777777777 | 44 | 10 | 0.0555555555555555 | 0 |
| IGF2R-201 | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | GO:0048009 | Not Cancer Driver | No | 233 | 0.0935367322360497 | 257 | 13 | 0.0052187876354877 | 0 |
| IGFBP5-201 | IGFBP5 | P24593 | Insulin-like growth factor-binding protein 5 | chr2 | GO:0048009 | Not Cancer Driver | No | 23 | 0.0845588235294117 | 112 | 18 | 0.0661764705882353 | 0 |
| IRS1-201 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0048009 | Not Cancer Driver | No | 118 | 0.0950080515297906 | 1075 | 104 | 0.0837359098228663 | 2 |
| MAP2K1-201 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | GO:0048009 | Census, Compendium | Yes | 83 | 0.2111959287531806 | 96 | 22 | 0.0559796437659033 | 5 |
| MAP2K2-201 | MAP2K2 | P36507 | Dual specificity mitogen-activated protein kinase kinase 2 | chr19 | GO:0048009 | Census | Yes | 45 | 0.1125 | 107 | 13 | 0.0325 | 3 |
| MAP2K5-201 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | GO:0048009 | Not Cancer Driver | No | 26 | 0.0580357142857142 | 85 | 6 | 0.0133928571428571 | 0 |
| MAPK1-201 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:0048009 | Census, Compendium | Yes | 52 | 0.1444444444444444 | 2 | 0 | 0.0 | 6 |
| MAPK3-201 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0048009 | Not Cancer Driver | No | 32 | 0.0844327176781002 | 49 | 3 | 0.0079155672823219 | 0 |
| PDPK1-202 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0048009 | Not Cancer Driver | No | 23 | 0.0413669064748201 | 121 | 9 | 0.0161870503597122 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0048009 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0048009 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PLCB1-201 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0048009 | Not Cancer Driver | No | 264 | 0.2171052631578947 | 484 | 85 | 0.0699013157894736 | 0 |
| RAF1-201 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | GO:0048009 | Census, Compendium | Yes | 64 | 0.0987654320987654 | 169 | 30 | 0.0462962962962962 | 18 |
| SHC1-202 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0048009 | Not Cancer Driver | No | 58 | 0.0994854202401372 | 400 | 41 | 0.0703259005145797 | 0 |
| SOS1-202 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0048009 | Compendium | Yes | 155 | 0.1162790697674418 | 459 | 47 | 0.0352588147036759 | 32 |
| TSC2-201 | TSC2 | P49815 | Tuberin | chr16 | GO:0048009 | Census, Compendium | Yes | 156 | 0.0863309352517985 | 568 | 40 | 0.0221361372440509 | 49 |