Total number of protein in "GO:0048511" GO term: 65
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATG7-226 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | GO:0048511 | Compendium | Yes | 60 | 0.0853485064011379 | 54 | 6 | 0.0085348506401137 | 6 |
| BTRC-202 | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | GO:0048511 | Not Cancer Driver | No | 57 | 0.0942148760330578 | 45 | 3 | 0.0049586776859504 | 0 |
| CBX3-202 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | GO:0048511 | Not Cancer Driver | No | 18 | 0.0983606557377049 | 119 | 13 | 0.0710382513661202 | 0 |
| CCAR2-201 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | GO:0048511 | Not Cancer Driver | No | 83 | 0.0899241603466955 | 531 | 51 | 0.0552546045503792 | 0 |
| CDK1-203 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0048511 | Not Cancer Driver | No | 26 | 0.0875420875420875 | 1 | 0 | 0.0 | 0 |
| CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0048511 | Not Cancer Driver | No | 38 | 0.1301369863013698 | 5 | 0 | 0.0 | 0 |
| CDK5R1-201 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0048511 | Not Cancer Driver | No | 29 | 0.0944625407166123 | 103 | 10 | 0.0325732899022801 | 0 |
| CIPC-201 | CIPC | Q9C0C6 | CLOCK-interacting pacemaker | chr14 | GO:0048511 | Not Cancer Driver | No | 28 | 0.0701754385964912 | 355 | 27 | 0.0676691729323308 | 0 |
| CREBBP-201 | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0048511 | Census, Compendium | Yes | 217 | 0.0888615888615888 | 1801 | 91 | 0.0372645372645372 | 30 |
| CREM-215 | CREM | Q03060 | cAMP-responsive element modulator | chr10 | GO:0048511 | Not Cancer Driver | No | 20 | 0.0579710144927536 | 290 | 16 | 0.0463768115942029 | 0 |
| CRTC1-201 | CRTC1 | Q6UUV9 | CREB-regulated transcription coactivator 1 | chr19 | GO:0048511 | Census, Compendium | Yes | 46 | 0.0725552050473186 | 607 | 45 | 0.0709779179810725 | 0 |
| CSNK2A1-201 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0048511 | Not Cancer Driver | No | 47 | 0.1202046035805626 | 75 | 6 | 0.0153452685421994 | 4 |
| CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0048511 | Not Cancer Driver | No | 54 | 0.0711462450592885 | 102 | 2 | 0.0026350461133069 | 0 |
| DBP-201 | DBP | Q10586 | D site-binding protein | chr19 | GO:0048511 | Not Cancer Driver | No | 20 | 0.0615384615384615 | 280 | 16 | 0.0492307692307692 | 0 |
| DDB1-201 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0048511 | Not Cancer Driver | No | 98 | 0.0859649122807017 | 50 | 8 | 0.0070175438596491 | 3 |
| DDX5-201 | DDX5 | P17844 | Probable ATP-dependent RNA helicase DDX5 | chr17 | GO:0048511 | Census | Yes | 61 | 0.0993485342019544 | 225 | 18 | 0.0293159609120521 | 0 |
| DHX9-201 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | GO:0048511 | Compendium | Yes | 125 | 0.0984251968503937 | 332 | 30 | 0.0236220472440944 | 0 |
| DNM1L-219 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | GO:0048511 | Not Cancer Driver | No | 44 | 0.0597826086956521 | 211 | 15 | 0.0203804347826086 | 7 |
| DRD4-201 | DRD4 | P21917 | D(4) dopamine receptor | chr11 | GO:0048511 | Not Cancer Driver | No | 15 | 0.035799522673031 | 109 | 0 | 0.0 | 0 |
| DTL-201 | DTL | Q9NZJ0 | Denticleless protein homolog | chr1 | GO:0048511 | Not Cancer Driver | No | 53 | 0.0726027397260273 | 333 | 38 | 0.0520547945205479 | 0 |
| EZH2-203 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0048511 | Census, Compendium | Yes | 74 | 0.099195710455764 | 284 | 32 | 0.0428954423592493 | 11 |
| FBXL3-201 | FBXL3 | Q9UKT7 | F-box/LRR-repeat protein 3 | chr13 | GO:0048511 | Not Cancer Driver | No | 24 | 0.0560747663551401 | 30 | 5 | 0.0116822429906542 | 1 |
| FBXW11-201 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | GO:0048511 | Not Cancer Driver | No | 41 | 0.0756457564575645 | 20 | 2 | 0.003690036900369 | 6 |
| FBXW7-201 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0048511 | Census, Compendium | Yes | 289 | 0.4087694483734088 | 232 | 15 | 0.0212164073550212 | 17 |
| GRIN3A-201 | GRIN3A | Q8TCU5 | Glutamate receptor ionotropic, NMDA 3A | chr9 | GO:0048511 | Not Cancer Driver | No | 252 | 0.2260089686098654 | 183 | 19 | 0.0170403587443946 | 0 |
| HES7-201 | HES7 | Q9BYE0 | Transcription factor HES-7 | chr17 | GO:0048511 | Not Cancer Driver | No | 4 | 0.0177777777777777 | 167 | 4 | 0.0177777777777777 | 3 |
| HLF-201 | HLF | Q16534 | Hepatic leukemia factor | chr17 | GO:0048511 | Census | Yes | 46 | 0.1559322033898305 | 264 | 42 | 0.1423728813559322 | 0 |
| HNF4A-201 | HNF4A | P41235 | Hepatocyte nuclear factor 4-alpha | chr20 | GO:0048511 | Not Cancer Driver | No | 113 | 0.2383966244725738 | 127 | 44 | 0.0928270042194092 | 5 |
| KAT2B-201 | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0048511 | Not Cancer Driver | No | 78 | 0.09375 | 268 | 20 | 0.0240384615384615 | 0 |
| KDM5B-203 | KDM5B | Q9UGL1 | Lysine-specific demethylase 5B | chr1 | GO:0048511 | Not Cancer Driver | No | 152 | 0.0984455958549222 | 386 | 41 | 0.0265544041450777 | 0 |
| KDM5C-204 | KDM5C | P41229 | Lysine-specific demethylase 5C | chrX | GO:0048511 | Census, Compendium | Yes | 129 | 0.0826923076923076 | 499 | 38 | 0.0243589743589743 | 10 |
| MAGEL2-201 | MAGEL2 | Q9UJ55 | MAGE-like protein 2 | chr15 | GO:0048511 | Not Cancer Driver | No | 157 | 0.1257005604483587 | 1010 | 104 | 0.0832666132906325 | 0 |
| MAPK10-319 | MAPK10 | P53779 | Mitogen-activated protein kinase 10 | chr4 | GO:0048511 | Not Cancer Driver | No | 72 | 0.1551724137931034 | 107 | 15 | 0.0323275862068965 | 0 |
| MAPK8-206 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0048511 | Not Cancer Driver | No | 52 | 0.1217798594847775 | 94 | 9 | 0.0210772833723653 | 0 |
| MAPK9-207 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0048511 | Not Cancer Driver | No | 37 | 0.0872641509433962 | 90 | 3 | 0.0070754716981132 | 0 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0048511 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
| NFKB2-211 | NFKB2 | Q00653 | Nuclear factor NF-kappa-B p100 subunit | chr10 | GO:0048511 | Census, Compendium | Yes | 61 | 0.0677777777777777 | 513 | 34 | 0.0377777777777777 | 0 |
| NFYA-201 | NFYA | P23511 | Nuclear transcription factor Y subunit alpha | chr6 | GO:0048511 | Not Cancer Driver | No | 16 | 0.0461095100864553 | 187 | 15 | 0.0432276657060518 | 0 |
| NKX2-1-203 | NKX2-1 | P43699 | Homeobox protein Nkx-2.1 | chr14 | GO:0048511 | Census, Compendium | Yes | 34 | 0.091644204851752 | 336 | 32 | 0.0862533692722372 | 6 |
| NLGN1-203 | NLGN1 | Q8N2Q7 | Neuroligin-1 | chr3 | GO:0048511 | Not Cancer Driver | No | 174 | 0.20162224797219 | 250 | 52 | 0.0602549246813441 | 4 |
| OPN4-201 | OPN4 | Q9UHM6 | Melanopsin | chr10 | GO:0048511 | Not Cancer Driver | No | 64 | 0.1338912133891213 | 89 | 8 | 0.0167364016736401 | 0 |
| PIWIL2-201 | PIWIL2 | Q8TC59 | Piwi-like protein 2 | chr8 | GO:0048511 | Not Cancer Driver | No | 104 | 0.1068859198355601 | 232 | 32 | 0.0328879753340185 | 0 |
| PPARG-201 | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0048511 | Census | Yes | 60 | 0.1188118811881188 | 44 | 3 | 0.0059405940594059 | 3 |
| PRKAA1-204 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0048511 | Not Cancer Driver | No | 54 | 0.0966010733452593 | 124 | 13 | 0.0232558139534883 | 0 |
| PRKAA2-201 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0048511 | Not Cancer Driver | No | 90 | 0.1630434782608695 | 98 | 18 | 0.0326086956521739 | 0 |
| PRKCG-201 | PRKCG | P05129 | Protein kinase C gamma type | chr19 | GO:0048511 | Not Cancer Driver | No | 141 | 0.2022955523672883 | 152 | 36 | 0.0516499282639885 | 4 |
| PRKDC-201 | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0048511 | Not Cancer Driver | No | 385 | 0.0932655038759689 | 421 | 43 | 0.0104166666666666 | 2 |
| PSPC1-201 | PSPC1 | Q8WXF1 | Paraspeckle component 1 | chr13 | GO:0048511 | Not Cancer Driver | No | 73 | 0.1395793499043977 | 368 | 61 | 0.1166347992351816 | 0 |
| RACK1-227 | RACK1 | P63244 | Small ribosomal subunit protein RACK1 | chr5 | GO:0048511 | Not Cancer Driver | No | 27 | 0.085173501577287 | 13 | 0 | 0.0 | 0 |
| ROCK2-202 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | GO:0048511 | Not Cancer Driver | No | 110 | 0.0792507204610951 | 734 | 61 | 0.0439481268011527 | 0 |
| RORB-202 | RORB | Q92753 | Nuclear receptor ROR-beta | chr9 | GO:0048511 | Not Cancer Driver | No | 75 | 0.1595744680851064 | 87 | 15 | 0.0319148936170212 | 1 |
| SFPQ-201 | SFPQ | P23246 | Splicing factor, proline- and glutamine-rich | chr1 | GO:0048511 | Census | Yes | 37 | 0.0523338048090523 | 596 | 27 | 0.0381895332390381 | 0 |
| SIAH2-201 | SIAH2 | O43255 | E3 ubiquitin-protein ligase SIAH2 | chr3 | GO:0048511 | Not Cancer Driver | No | 34 | 0.1049382716049382 | 68 | 2 | 0.0061728395061728 | 0 |
| SIK1-201 | SIK1 | P57059 | Serine/threonine-protein kinase SIK1 | chr21 | GO:0048511 | Not Cancer Driver | No | 65 | 0.0830140485312899 | 334 | 25 | 0.0319284802043422 | 3 |
| SIN3A-202 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | GO:0048511 | Compendium | Yes | 137 | 0.1076197957580518 | 617 | 60 | 0.0471327572663 | 0 |
| SP1-201 | SP1 | P08047 | Transcription factor Sp1 | chr12 | GO:0048511 | Not Cancer Driver | No | 67 | 0.0853503184713375 | 601 | 53 | 0.0675159235668789 | 0 |
| SPSB4-201 | SPSB4 | Q96A44 | SPRY domain-containing SOCS box protein 4 | chr3 | GO:0048511 | Not Cancer Driver | No | 35 | 0.1282051282051282 | 75 | 1 | 0.0036630036630036 | 0 |
| SRRD-201 | SRRD | Q9UH36 | SRR1-like protein | chr22 | GO:0048511 | Not Cancer Driver | No | 19 | 0.0560471976401179 | 64 | 3 | 0.0088495575221238 | 0 |
| TARDBP-201 | TARDBP | Q13148 | TAR DNA-binding protein 43 | chr1 | GO:0048511 | Not Cancer Driver | No | 36 | 0.0869565217391304 | 202 | 12 | 0.0289855072463768 | 21 |
| TEF-201 | TEF | Q10587 | Thyrotroph embryonic factor | chr22 | GO:0048511 | Not Cancer Driver | No | 21 | 0.0693069306930693 | 266 | 19 | 0.0627062706270627 | 0 |
| TOP2A-201 | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:0048511 | Compendium | Yes | 115 | 0.0751143043762246 | 509 | 46 | 0.0300457217504898 | 0 |
| TWIST1-201 | TWIST1 | Q15672 | Twist-related protein 1 | chr7 | GO:0048511 | Not Cancer Driver | No | 21 | 0.1039603960396039 | 132 | 9 | 0.0445544554455445 | 6 |
| UBE3A-228 | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | GO:0048511 | Not Cancer Driver | No | 90 | 0.1028571428571428 | 136 | 16 | 0.0182857142857142 | 0 |
| USP7-201 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | GO:0048511 | Not Cancer Driver | No | 135 | 0.1225045372050816 | 215 | 34 | 0.0308529945553539 | 7 |
| USP9X-202 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0048511 | Census, Compendium | Yes | 243 | 0.0951448707909162 | 405 | 33 | 0.0129209083790133 | 1 |