Total number of protein in "GO:0048661" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AIF1-203 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:0048661 | Not Cancer Driver | No | 12 | 0.0816326530612244 | 61 | 5 | 0.0340136054421768 | 0 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0048661 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| BMP4-201 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0048661 | Not Cancer Driver | No | 69 | 0.1691176470588235 | 142 | 20 | 0.0490196078431372 | 5 |
| CCL5-201 | CCL5 | P13501 | C-C motif chemokine 5 | chr17 | GO:0048661 | Not Cancer Driver | No | 7 | 0.0769230769230769 | 0 | 0 | 0.0 | 0 |
| CCN4-202 | CCN4 | O95388 | CCN family member 4 | chr8 | GO:0048661 | Not Cancer Driver | No | 84 | 0.2288828337874659 | 20 | 7 | 0.0190735694822888 | 0 |
| CDH13-209 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0048661 | Not Cancer Driver | No | 128 | 0.1795231416549789 | 236 | 47 | 0.0659186535764375 | 0 |
| CX3CL1-201 | CX3CL1 | P78423 | Fractalkine | chr16 | GO:0048661 | Not Cancer Driver | No | 53 | 0.1335012594458438 | 259 | 36 | 0.0906801007556675 | 0 |
| EDN1-201 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0048661 | Not Cancer Driver | No | 27 | 0.1273584905660377 | 98 | 16 | 0.0754716981132075 | 3 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0048661 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
| ELANE-201 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0048661 | Not Cancer Driver | No | 31 | 0.1161048689138576 | 18 | 1 | 0.0037453183520599 | 65 |
| ENST00000560629 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0048661 | Not Cancer Driver | No | 92 | 0.1168996188055908 | 68 | 6 | 0.0076238881829733 | 27 |
| ENST00000647725 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | GO:0048661 | Census, Compendium | Yes | 83 | 0.1225997045790251 | 449 | 54 | 0.0797636632200886 | 3 |
| EREG-201 | EREG | O14944 | Proepiregulin | chr4 | GO:0048661 | Not Cancer Driver | No | 19 | 0.1124260355029585 | 10 | 2 | 0.0118343195266272 | 0 |
| FOXP1-254 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | GO:0048661 | Census, Compendium | Yes | 83 | 0.1225997045790251 | 449 | 54 | 0.0797636632200886 | 3 |
| HBEGF-201 | HBEGF | Q99075 | Proheparin-binding EGF-like growth factor | chr5 | GO:0048661 | Not Cancer Driver | No | 11 | 0.0528846153846153 | 63 | 2 | 0.0096153846153846 | 0 |
| HDAC1-201 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:0048661 | Not Cancer Driver | No | 30 | 0.0622406639004149 | 135 | 5 | 0.0103734439834024 | 0 |
| HES5-201 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0048661 | Not Cancer Driver | No | 1 | 0.0060240963855421 | 73 | 0 | 0.0 | 0 |
| HMOX1-201 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0048661 | Not Cancer Driver | No | 33 | 0.1145833333333333 | 82 | 11 | 0.0381944444444444 | 0 |
| ID2-203 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | GO:0048661 | Not Cancer Driver | No | 13 | 0.0970149253731343 | 52 | 6 | 0.044776119402985 | 0 |
| IGF1-201 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0048661 | Not Cancer Driver | No | 30 | 0.1538461538461538 | 87 | 18 | 0.0923076923076923 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0048661 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| IL13-201 | IL13 | P35225 | Interleukin-13 | chr5 | GO:0048661 | Not Cancer Driver | No | 12 | 0.0821917808219178 | 0 | 0 | 0.0 | 0 |
| IL18-201 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0048661 | Not Cancer Driver | No | 11 | 0.0569948186528497 | 16 | 2 | 0.0103626943005181 | 0 |
| IL6-201 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0048661 | Not Cancer Driver | No | 32 | 0.1509433962264151 | 58 | 6 | 0.0283018867924528 | 0 |
| IL6R-202 | IL6R | P08887 | Interleukin-6 receptor subunit alpha | chr1 | GO:0048661 | Not Cancer Driver | No | 43 | 0.0918803418803418 | 166 | 19 | 0.0405982905982906 | 1 |
| IRAK1-203 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | GO:0048661 | Compendium | Yes | 60 | 0.0842696629213483 | 338 | 35 | 0.0491573033707865 | 0 |
| IRAK4-212 | IRAK4 | Q9NWZ3 | Interleukin-1 receptor-associated kinase 4 | chr12 | GO:0048661 | Not Cancer Driver | No | 50 | 0.108695652173913 | 116 | 17 | 0.0369565217391304 | 2 |
| ITGA2-201 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0048661 | Not Cancer Driver | No | 116 | 0.0982218458933107 | 26 | 0 | 0.0 | 0 |
| ITGB3-201 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0048661 | Not Cancer Driver | No | 92 | 0.116751269035533 | 68 | 5 | 0.0063451776649746 | 28 |
| MNAT1-201 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:0048661 | Not Cancer Driver | No | 20 | 0.0647249190938511 | 64 | 2 | 0.0064724919093851 | 0 |
| MYB-205 | MYB | P10242 | Transcriptional activator Myb | chr6 | GO:0048661 | Census | Yes | 69 | 0.1078125 | 528 | 57 | 0.0890625 | 0 |
| MYD88-209 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0048661 | Census, Compendium | Yes | 29 | 0.0979729729729729 | 47 | 2 | 0.0067567567567567 | 2 |
| NOTCH3-201 | NOTCH3 | Q9UM47 | Neurogenic locus notch homolog protein 3 | chr19 | GO:0048661 | Not Cancer Driver | No | 241 | 0.1038345540715209 | 560 | 61 | 0.0262817750969409 | 89 |
| NOX1-204 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:0048661 | Not Cancer Driver | No | 76 | 0.1347517730496454 | 18 | 5 | 0.0088652482269503 | 0 |
| NPY5R-201 | NPY5R | Q15761 | Neuropeptide Y receptor type 5 | chr4 | GO:0048661 | Not Cancer Driver | No | 112 | 0.251685393258427 | 44 | 11 | 0.0247191011235955 | 0 |
| NR4A3-203 | NR4A3 | Q92570 | Nuclear receptor subfamily 4 group A member 3 | chr9 | GO:0048661 | Census | Yes | 52 | 0.0830670926517571 | 298 | 29 | 0.0463258785942492 | 0 |
| PDGFB-201 | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0048661 | Census | Yes | 30 | 0.1244813278008298 | 99 | 16 | 0.0663900414937759 | 2 |
| PDGFD-202 | PDGFD | Q9GZP0 | Platelet-derived growth factor D | chr11 | GO:0048661 | Not Cancer Driver | No | 72 | 0.1945945945945946 | 38 | 14 | 0.0378378378378378 | 0 |
| PDGFRB-201 | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0048661 | Census, Compendium | Yes | 134 | 0.1211573236889692 | 233 | 40 | 0.0361663652802893 | 7 |
| PHB1-201 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0048661 | Not Cancer Driver | No | 21 | 0.0772058823529411 | 4 | 1 | 0.0036764705882352 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0048661 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0048661 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PTAFR-202 | PTAFR | P25105 | Platelet-activating factor receptor | chr1 | GO:0048661 | Not Cancer Driver | No | 32 | 0.0935672514619883 | 0 | 0 | 0.0 | 0 |
| PTGS2-201 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0048661 | Not Cancer Driver | No | 68 | 0.1125827814569536 | 31 | 4 | 0.0066225165562913 | 0 |
| RBPMS2-201 | RBPMS2 | Q6ZRY4 | RNA-binding protein with multiple splicing 2 | chr15 | GO:0048661 | Not Cancer Driver | No | 12 | 0.0574162679425837 | 55 | 1 | 0.0047846889952153 | 0 |
| RPS6KB1-201 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0048661 | Not Cancer Driver | No | 36 | 0.0685714285714285 | 226 | 22 | 0.0419047619047619 | 0 |
| S1PR1-201 | S1PR1 | P21453 | Sphingosine 1-phosphate receptor 1 | chr1 | GO:0048661 | Not Cancer Driver | No | 69 | 0.1806282722513089 | 29 | 5 | 0.013089005235602 | 0 |
| SERPINF2-204 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0048661 | Not Cancer Driver | No | 46 | 0.0936863543788187 | 113 | 14 | 0.0285132382892057 | 1 |
| SMPD3-201 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0048661 | Not Cancer Driver | No | 73 | 0.1114503816793893 | 224 | 26 | 0.0396946564885496 | 0 |
| STAT1-201 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0048661 | Not Cancer Driver | No | 100 | 0.1333333333333333 | 144 | 16 | 0.0213333333333333 | 23 |
| TGFB1-201 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0048661 | Not Cancer Driver | No | 30 | 0.0769230769230769 | 44 | 3 | 0.0076923076923076 | 8 |
| THBS1-201 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0048661 | Not Cancer Driver | No | 153 | 0.1307692307692307 | 321 | 50 | 0.0427350427350427 | 0 |
| TLR4-201 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0048661 | Not Cancer Driver | No | 253 | 0.301549463647199 | 0 | 0 | 0.0 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0048661 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| ZNF143-203 | ZNF143 | P52747 | Zinc finger protein 143 | chr11 | GO:0048661 | Not Cancer Driver | No | 55 | 0.0862068965517241 | 425 | 40 | 0.0626959247648902 | 0 |