Total number of protein in "GO:0050727" GO term: 91
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABHD12-201 | ABHD12 | Q8N2K0 | Lysophosphatidylserine lipase ABHD12 | chr20 | GO:0050727 | Not Cancer Driver | No | 24 | 0.0603015075376884 | 8 | 0 | 0.0 | 1 |
| ACE2-201 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | GO:0050727 | Not Cancer Driver | No | 67 | 0.0832298136645962 | 68 | 4 | 0.0049689440993788 | 0 |
| ADAMTS12-203 | ADAMTS12 | P58397 | A disintegrin and metalloproteinase with thrombospondin motifs 12 | chr5 | GO:0050727 | Not Cancer Driver | No | 433 | 0.2716436637390213 | 375 | 112 | 0.0702634880803011 | 0 |
| AGER-206 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0050727 | Not Cancer Driver | No | 17 | 0.042079207920792 | 297 | 12 | 0.0297029702970297 | 0 |
| AGTR1-201 | AGTR1 | P30556 | Type-1 angiotensin II receptor | chr3 | GO:0050727 | Not Cancer Driver | No | 70 | 0.1949860724233983 | 0 | 0 | 0.0 | 1 |
| AHSG-202 | AHSG | P02765 | Alpha-2-HS-glycoprotein | chr3 | GO:0050727 | Not Cancer Driver | No | 61 | 0.1662125340599455 | 132 | 33 | 0.0899182561307901 | 0 |
| AKNA-206 | AKNA | Q7Z591 | Microtubule organization protein AKNA | chr9 | GO:0050727 | Not Cancer Driver | No | 149 | 0.103544127866574 | 1418 | 152 | 0.1056289089645587 | 0 |
| ALOX15-201 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0050727 | Not Cancer Driver | No | 64 | 0.0966767371601208 | 46 | 4 | 0.0060422960725075 | 0 |
| ALOX5-201 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0050727 | Not Cancer Driver | No | 100 | 0.1483679525222551 | 16 | 1 | 0.0014836795252225 | 0 |
| ANXA1-201 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0050727 | Not Cancer Driver | No | 36 | 0.1040462427745664 | 61 | 7 | 0.0202312138728323 | 0 |
| AREL1-201 | AREL1 | O15033 | Apoptosis-resistant E3 ubiquitin protein ligase 1 | chr14 | GO:0050727 | Not Cancer Driver | No | 70 | 0.0850546780072904 | 92 | 8 | 0.0097205346294046 | 0 |
| ARMH4-201 | ARMH4 | Q86TY3 | Armadillo-like helical domain-containing protein 4 | chr14 | GO:0050727 | Not Cancer Driver | No | 86 | 0.1111111111111111 | 679 | 78 | 0.1007751937984496 | 0 |
| BAP1-202 | BAP1 | Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | chr3 | GO:0050727 | Census, Compendium | Yes | 116 | 0.1591220850480109 | 419 | 42 | 0.0576131687242798 | 4 |
| BCL6-202 | BCL6 | P41182 | B-cell lymphoma 6 protein | chr3 | GO:0050727 | Census, Compendium | Yes | 91 | 0.1288951841359773 | 328 | 45 | 0.0637393767705382 | 0 |
| BIRC2-201 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0050727 | Not Cancer Driver | No | 49 | 0.0792880258899676 | 85 | 7 | 0.0113268608414239 | 0 |
| BIRC3-201 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | GO:0050727 | Census, Compendium | Yes | 53 | 0.0877483443708609 | 98 | 10 | 0.0165562913907284 | 0 |
| BRD4-213 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | GO:0050727 | Census, Compendium | Yes | 143 | 0.1049926578560939 | 1184 | 132 | 0.0969162995594713 | 0 |
| BST1-201 | BST1 | Q10588 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | chr4 | GO:0050727 | Not Cancer Driver | No | 29 | 0.0911949685534591 | 11 | 0 | 0.0 | 0 |
| CARD16-204 | CARD16 | Q5EG05 | Caspase recruitment domain-containing protein 16 | chr11 | GO:0050727 | Not Cancer Driver | No | 26 | 0.1319796954314721 | 23 | 5 | 0.0253807106598984 | 0 |
| CASP1-212 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0050727 | Not Cancer Driver | No | 54 | 0.1336633663366336 | 88 | 12 | 0.0297029702970297 | 0 |
| CASP4-203 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0050727 | Not Cancer Driver | No | 41 | 0.1087533156498673 | 103 | 11 | 0.0291777188328912 | 0 |
| CCR2-201 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0050727 | Not Cancer Driver | No | 56 | 0.1497326203208556 | 23 | 2 | 0.0053475935828877 | 0 |
| CELF1-202 | CELF1 | Q92879 | CUGBP Elav-like family member 1 | chr11 | GO:0050727 | Not Cancer Driver | No | 50 | 0.102880658436214 | 166 | 14 | 0.0288065843621399 | 0 |
| CMA1-202 | CMA1 | P23946 | Chymase | chr14 | GO:0050727 | Not Cancer Driver | No | 39 | 0.1578947368421052 | 9 | 1 | 0.0040485829959514 | 0 |
| CYLD-203 | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0050727 | Census, Compendium | Yes | 76 | 0.0794979079497908 | 213 | 21 | 0.0219665271966527 | 3 |
| DAGLB-201 | DAGLB | Q8NCG7 | Diacylglycerol lipase-beta | chr7 | GO:0050727 | Not Cancer Driver | No | 51 | 0.0758928571428571 | 37 | 3 | 0.0044642857142857 | 0 |
| DROSHA-201 | DROSHA | Q9NRR4 | Ribonuclease 3 | chr5 | GO:0050727 | Census, Compendium | Yes | 139 | 0.1011644832605531 | 688 | 76 | 0.0553129548762736 | 0 |
| DUOXA1-215 | DUOXA1 | Q1HG43 | Dual oxidase maturation factor 1 | chr15 | GO:0050727 | Not Cancer Driver | No | 29 | 0.0845481049562682 | 38 | 4 | 0.0116618075801749 | 0 |
| DUOXA2-201 | DUOXA2 | Q1HG44 | Dual oxidase maturation factor 2 | chr15 | GO:0050727 | Not Cancer Driver | No | 22 | 0.06875 | 0 | 0 | 0.0 | 0 |
| ENST00000572919 | SHPK | Q9UHJ6 | Sedoheptulokinase | chr17 | GO:0050727 | Not Cancer Driver | No | 27 | 0.0564853556485355 | 31 | 1 | 0.002092050209205 | 0 |
| ENST00000647725 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | GO:0050727 | Census, Compendium | Yes | 83 | 0.1225997045790251 | 449 | 54 | 0.0797636632200886 | 3 |
| ESR1-201 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0050727 | Census, Compendium | Yes | 92 | 0.1546218487394958 | 198 | 19 | 0.0319327731092436 | 2 |
| FANCA-202 | FANCA | O15360 | Fanconi anemia group A protein | chr16 | GO:0050727 | Census, Compendium | Yes | 121 | 0.0831615120274914 | 157 | 13 | 0.00893470790378 | 26 |
| FANCD2-212 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | GO:0050727 | Census, Compendium | Yes | 116 | 0.0799448656099241 | 182 | 9 | 0.0062026188835286 | 3 |
| FBXL2-216 | FBXL2 | Q9UKC9 | F-box/LRR-repeat protein 2 | chr3 | GO:0050727 | Not Cancer Driver | No | 31 | 0.0732860520094562 | 0 | 0 | 0.0 | 0 |
| FOXP1-254 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | GO:0050727 | Census, Compendium | Yes | 83 | 0.1225997045790251 | 449 | 54 | 0.0797636632200886 | 3 |
| GGT1-202 | GGT1 | P19440 | Glutathione hydrolase 1 proenzyme | chr22 | GO:0050727 | Not Cancer Driver | No | 47 | 0.0826010544815465 | 89 | 5 | 0.0087873462214411 | 0 |
| GRN-201 | GRN | P28799 | Progranulin | chr17 | GO:0050727 | Not Cancer Driver | No | 64 | 0.1079258010118043 | 29 | 4 | 0.0067453625632377 | 1 |
| HCK-202 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0050727 | Not Cancer Driver | No | 89 | 0.1692015209125475 | 124 | 22 | 0.0418250950570342 | 0 |
| IL1R1-205 | IL1R1 | P14778 | Interleukin-1 receptor type 1 | chr2 | GO:0050727 | Not Cancer Driver | No | 61 | 0.1072056239015817 | 60 | 6 | 0.0105448154657293 | 0 |
| IL1RL2-201 | IL1RL2 | Q9HB29 | Interleukin-1 receptor-like 2 | chr2 | GO:0050727 | Not Cancer Driver | No | 82 | 0.1426086956521739 | 11 | 1 | 0.0017391304347826 | 0 |
| IL20-202 | IL20 | Q9NYY1 | Interleukin-20 | chr1 | GO:0050727 | Not Cancer Driver | No | 20 | 0.1136363636363636 | 0 | 0 | 0.0 | 0 |
| IL37-201 | IL37 | Q9NZH6 | Interleukin-37 | chr2 | GO:0050727 | Not Cancer Driver | No | 45 | 0.2064220183486238 | 72 | 12 | 0.055045871559633 | 1 |
| IRF3-203 | IRF3 | Q14653 | Interferon regulatory factor 3 | chr19 | GO:0050727 | Not Cancer Driver | No | 23 | 0.0538641686182669 | 205 | 17 | 0.0398126463700234 | 1 |
| JAK2-201 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0050727 | Census, Compendium | Yes | 81 | 0.0715547703180212 | 59 | 4 | 0.0035335689045936 | 4 |
| LACC1-201 | LACC1 | Q8IV20 | Purine nucleoside phosphorylase LACC1 | chr13 | GO:0050727 | Not Cancer Driver | No | 40 | 0.0930232558139534 | 4 | 0 | 0.0 | 1 |
| LETMD1-201 | LETMD1 | Q6P1Q0 | LETM1 domain-containing protein 1 | chr12 | GO:0050727 | Not Cancer Driver | No | 36 | 0.1 | 0 | 0 | 0.0 | 0 |
| LRRC19-201 | LRRC19 | Q9H756 | Leucine-rich repeat-containing protein 19 | chr9 | GO:0050727 | Not Cancer Driver | No | 24 | 0.0648648648648648 | 31 | 3 | 0.0081081081081081 | 0 |
| MAS1-202 | MAS1 | P04201 | Proto-oncogene Mas | chr6 | GO:0050727 | Not Cancer Driver | No | 36 | 0.1107692307692307 | 5 | 2 | 0.0061538461538461 | 0 |
| MCPH1-201 | MCPH1 | Q8NEM0 | Microcephalin | chr8 | GO:0050727 | Not Cancer Driver | No | 84 | 0.1005988023952095 | 454 | 46 | 0.0550898203592814 | 1 |
| MGLL-203 | MGLL | Q99685 | Monoglyceride lipase | chr3 | GO:0050727 | Not Cancer Driver | No | 44 | 0.1452145214521452 | 30 | 7 | 0.0231023102310231 | 0 |
| MYD88-209 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0050727 | Census, Compendium | Yes | 29 | 0.0979729729729729 | 47 | 2 | 0.0067567567567567 | 2 |
| NLRP1-208 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0050727 | Not Cancer Driver | No | 169 | 0.1147318397827562 | 341 | 45 | 0.0305498981670061 | 6 |
| NLRP11-201 | NLRP11 | P59045 | NACHT, LRR and PYD domains-containing protein 11 | chr19 | GO:0050727 | Not Cancer Driver | No | 178 | 0.1723136495643756 | 25 | 1 | 0.0009680542110358 | 0 |
| NLRP13-201 | NLRP13 | Q86W25 | NACHT, LRR and PYD domains-containing protein 13 | chr19 | GO:0050727 | Not Cancer Driver | No | 237 | 0.2272291466922339 | 121 | 38 | 0.0364333652924257 | 0 |
| NLRP14-201 | NLRP14 | Q86W24 | NACHT, LRR and PYD domains-containing protein 14 | chr11 | GO:0050727 | Not Cancer Driver | No | 201 | 0.1838975297346752 | 47 | 8 | 0.0073193046660567 | 0 |
| NLRP2-208 | NLRP2 | Q9NX02 | NACHT, LRR and PYD domains-containing protein 2 | chr19 | GO:0050727 | Not Cancer Driver | No | 207 | 0.1949152542372881 | 60 | 12 | 0.0112994350282485 | 0 |
| NLRP4-201 | NLRP4 | Q96MN2 | NACHT, LRR and PYD domains-containing protein 4 | chr19 | GO:0050727 | Not Cancer Driver | No | 264 | 0.2655935613682093 | 26 | 11 | 0.011066398390342 | 0 |
| NLRP5-201 | NLRP5 | P59047 | NACHT, LRR and PYD domains-containing protein 5 | chr19 | GO:0050727 | Not Cancer Driver | No | 300 | 0.25 | 144 | 23 | 0.0191666666666666 | 0 |
| NLRP6-201 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0050727 | Not Cancer Driver | No | 68 | 0.0762331838565022 | 205 | 11 | 0.0123318385650224 | 0 |
| NLRP7-207 | NLRP7 | Q8WX94 | NACHT, LRR and PYD domains-containing protein 7 | chr19 | GO:0050727 | Not Cancer Driver | No | 203 | 0.2071428571428571 | 71 | 11 | 0.0112244897959183 | 7 |
| NLRP8-201 | NLRP8 | Q86W28 | NACHT, LRR and PYD domains-containing protein 8 | chr19 | GO:0050727 | Not Cancer Driver | No | 272 | 0.2595419847328244 | 51 | 14 | 0.0133587786259541 | 0 |
| NLRP9-201 | NLRP9 | Q7RTR0 | NACHT, LRR and PYD domains-containing protein 9 | chr19 | GO:0050727 | Not Cancer Driver | No | 193 | 0.1947527749747729 | 0 | 0 | 0.0 | 0 |
| NOD2-201 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0050727 | Not Cancer Driver | No | 130 | 0.125 | 41 | 3 | 0.0028846153846153 | 15 |
| NR1D2-201 | NR1D2 | Q14995 | Nuclear receptor subfamily 1 group D member 2 | chr3 | GO:0050727 | Not Cancer Driver | No | 52 | 0.0898100172711571 | 227 | 16 | 0.0276338514680483 | 0 |
| PARK7-201 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0050727 | Not Cancer Driver | No | 8 | 0.0423280423280423 | 30 | 0 | 0.0 | 6 |
| PGLYRP2-202 | PGLYRP2 | Q96PD5 | N-acetylmuramoyl-L-alanine amidase | chr19 | GO:0050727 | Not Cancer Driver | No | 82 | 0.1423611111111111 | 163 | 22 | 0.0381944444444444 | 0 |
| PIK3AP1-201 | PIK3AP1 | Q6ZUJ8 | Phosphoinositide 3-kinase adapter protein 1 | chr10 | GO:0050727 | Not Cancer Driver | No | 101 | 0.1254658385093167 | 407 | 55 | 0.0683229813664596 | 0 |
| PSMA6-201 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | GO:0050727 | Not Cancer Driver | No | 33 | 0.1341463414634146 | 3 | 0 | 0.0 | 0 |
| PTGES-201 | PTGES | O14684 | Prostaglandin E synthase | chr9 | GO:0050727 | Not Cancer Driver | No | 6 | 0.0394736842105263 | 0 | 0 | 0.0 | 0 |
| PTGS2-201 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0050727 | Not Cancer Driver | No | 68 | 0.1125827814569536 | 31 | 4 | 0.0066225165562913 | 0 |
| RELA-202 | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0050727 | Compendium | Yes | 53 | 0.0961887477313974 | 401 | 32 | 0.058076225045372 | 0 |
| RICTOR-202 | RICTOR | Q6R327 | Rapamycin-insensitive companion of mTOR | chr5 | GO:0050727 | Not Cancer Driver | No | 144 | 0.0843091334894613 | 365 | 34 | 0.0199063231850117 | 0 |
| SBNO2-201 | SBNO2 | Q9Y2G9 | Protein strawberry notch homolog 2 | chr19 | GO:0050727 | Not Cancer Driver | No | 81 | 0.0592972181551976 | 458 | 24 | 0.0175695461200585 | 0 |
| SCGB1A1-201 | SCGB1A1 | P11684 | Uteroglobin | chr11 | GO:0050727 | Not Cancer Driver | No | 7 | 0.0769230769230769 | 14 | 1 | 0.0109890109890109 | 0 |
| SELE-201 | SELE | P16581 | E-selectin | chr1 | GO:0050727 | Not Cancer Driver | No | 110 | 0.180327868852459 | 12 | 0 | 0.0 | 0 |
| SEMA7A-201 | SEMA7A | O75326 | Semaphorin-7A | chr15 | GO:0050727 | Not Cancer Driver | No | 64 | 0.0960960960960961 | 150 | 19 | 0.0285285285285285 | 1 |
| SETD6-201 | SETD6 | Q8TBK2 | N-lysine methyltransferase SETD6 | chr16 | GO:0050727 | Not Cancer Driver | No | 33 | 0.0697674418604651 | 105 | 9 | 0.0190274841437632 | 0 |
| SHPK-201 | SHPK | Q9UHJ6 | Sedoheptulokinase | chr17 | GO:0050727 | Not Cancer Driver | No | 27 | 0.0564853556485355 | 31 | 1 | 0.002092050209205 | 0 |
| SPATA2-201 | SPATA2 | Q9UM82 | Spermatogenesis-associated protein 2 | chr20 | GO:0050727 | Not Cancer Driver | No | 56 | 0.1076923076923077 | 235 | 34 | 0.0653846153846153 | 0 |
| STING1-201 | STING1 | Q86WV6 | Stimulator of interferon genes protein | chr5 | GO:0050727 | Not Cancer Driver | No | 39 | 0.1029023746701846 | 66 | 12 | 0.0316622691292876 | 4 |
| STK39-201 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0050727 | Not Cancer Driver | No | 42 | 0.0770642201834862 | 183 | 13 | 0.0238532110091743 | 0 |
| TNC-202 | TNC | P24821 | Tenascin | chr9 | GO:0050727 | Census, Compendium | Yes | 241 | 0.1094956837800999 | 575 | 78 | 0.0354384370740572 | 2 |
| TNFSF4-201 | TNFSF4 | P23510 | Tumor necrosis factor ligand superfamily member 4 | chr1 | GO:0050727 | Not Cancer Driver | No | 17 | 0.0928961748633879 | 1 | 0 | 0.0 | 0 |
| TREX1-205 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0050727 | Not Cancer Driver | No | 24 | 0.0764331210191082 | 98 | 7 | 0.0222929936305732 | 17 |
| UFL1-201 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0050727 | Not Cancer Driver | No | 77 | 0.096977329974811 | 141 | 19 | 0.0239294710327455 | 0 |
| USP18-201 | USP18 | Q9UMW8 | Ubl carboxyl-terminal hydrolase 18 | chr22 | GO:0050727 | Not Cancer Driver | No | 24 | 0.064516129032258 | 29 | 3 | 0.0080645161290322 | 0 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0050727 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |
| XCL1-201 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0050727 | Not Cancer Driver | No | 25 | 0.219298245614035 | 35 | 10 | 0.087719298245614 | 0 |
| XIAP-202 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0050727 | Not Cancer Driver | No | 61 | 0.1227364185110664 | 55 | 2 | 0.0040241448692152 | 0 |
| ZBP1-201 | ZBP1 | Q9H171 | Z-DNA-binding protein 1 | chr20 | GO:0050727 | Not Cancer Driver | No | 70 | 0.1631701631701631 | 388 | 60 | 0.1398601398601398 | 0 |