Filter in search result
Please select a valid state.

Total number of protein in "GO:0050728" GO term:  112

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACOD1-201 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0050728 Not Cancer Driver No 0 0.0 36 0 0.0 0
ACP5-211 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0050728 Not Cancer Driver No 39 0.12 31 4 0.0123076923076923 8
ADA-201 ADA P00813 Adenosine deaminase chr20 GO:0050728 Not Cancer Driver No 43 0.1184573002754821 45 9 0.024793388429752 22
ADIPOQ-201 ADIPOQ Q15848 Adiponectin chr3 GO:0050728 Not Cancer Driver No 32 0.1311475409836065 92 16 0.0655737704918032 1
ADORA2A-201 ADORA2A P29274 Adenosine receptor A2a chr22 GO:0050728 Not Cancer Driver No 42 0.1019417475728155 93 8 0.0194174757281553 0
AHR-201 AHR P35869 Aryl hydrocarbon receptor chr7 GO:0050728 Not Cancer Driver No 95 0.1120283018867924 353 55 0.0648584905660377 0
ALOX5-201 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0050728 Not Cancer Driver No 100 0.1483679525222551 16 1 0.0014836795252225 0
AOAH-211 AOAH P28039 Acyloxyacyl hydrolase chr7 GO:0050728 Not Cancer Driver No 92 0.16 67 8 0.0139130434782608 0
APOA1-201 APOA1 P02647 Apolipoprotein A-I chr11 GO:0050728 Not Cancer Driver No 25 0.0936329588014981 131 9 0.0337078651685393 3
APOE-201 APOE P02649 Apolipoprotein E chr19 GO:0050728 Not Cancer Driver No 20 0.0630914826498422 124 5 0.0157728706624605 10
ARNT-202 ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0050728 Census Yes 61 0.0773130544993662 511 47 0.0595690747782002 0
BCR-201 BCR P11274 Breakpoint cluster region protein chr22 GO:0050728 Census, Compendium Yes 112 0.088119590873328 607 57 0.044846577498033 0
C1QTNF12-201 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0050728 Not Cancer Driver No 11 0.0364238410596026 105 4 0.0132450331125827 0
C1QTNF3-201 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0050728 Not Cancer Driver No 33 0.1341463414634146 73 12 0.048780487804878 0
CCN3-201 CCN3 P48745 CCN family member 3 chr8 GO:0050728 Not Cancer Driver No 49 0.1372549019607843 20 2 0.0056022408963585 0
CDH5-201 CDH5 P33151 Cadherin-5 chr16 GO:0050728 Not Cancer Driver No 121 0.1543367346938775 305 44 0.0561224489795918 0
CXCL17-202 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0050728 Not Cancer Driver No 6 0.0504201680672268 44 4 0.0336134453781512 0
CYLD-203 CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0050728 Census, Compendium Yes 76 0.0794979079497908 213 21 0.0219665271966527 3
ELANE-201 ELANE P08246 Neutrophil elastase chr19 GO:0050728 Not Cancer Driver No 31 0.1161048689138576 18 1 0.0037453183520599 65
ELF4-201 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX GO:0050728 Census, Compendium Yes 63 0.0950226244343891 487 46 0.0693815987933635 2
ENPP3-201 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0050728 Not Cancer Driver No 106 0.1211428571428571 57 12 0.0137142857142857 0
ENST00000637807 AHR P35869 Aryl hydrocarbon receptor chr7 GO:0050728 Not Cancer Driver No 90 0.1129234629861982 304 51 0.0639899623588456 0
EXTL3-201 EXTL3 O43909 Exostosin-like 3 chr8 GO:0050728 Not Cancer Driver No 101 0.1099020674646354 111 17 0.0184983677910772 5
FEM1A-201 FEM1A Q9BSK4 Protein fem-1 homolog A chr19 GO:0050728 Not Cancer Driver No 42 0.0627802690582959 162 13 0.0194319880418535 0
FFAR4-201 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0050728 Not Cancer Driver No 36 0.0997229916897507 0 0 0.0 0
FNDC4-201 FNDC4 Q9H6D8 Fibronectin type III domain-containing protein 4 chr2 GO:0050728 Not Cancer Driver No 17 0.0726495726495726 141 11 0.047008547008547 0
FOXF1-201 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0050728 Not Cancer Driver No 43 0.1134564643799472 196 16 0.0422163588390501 16
FPR2-201 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0050728 Not Cancer Driver No 92 0.2621082621082621 26 7 0.0199430199430199 0
FXR1-202 FXR1 P51114 RNA-binding protein FXR1 chr3 GO:0050728 Not Cancer Driver No 63 0.1014492753623188 312 40 0.0644122383252818 0
GATA3-201 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0050728 Census, Compendium Yes 99 0.2234762979683973 368 79 0.1783295711060948 2
GBA1-202 GBA1 P04062 Lysosomal acid glucosylceramidase chr1 GO:0050728 Not Cancer Driver No 60 0.1119402985074626 38 6 0.0111940298507462 157
GHRL-202 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0050728 Not Cancer Driver No 13 0.1111111111111111 52 8 0.0683760683760683 0
GHSR-201 GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0050728 Not Cancer Driver No 60 0.1639344262295081 4 0 0.0 2
GPER1-202 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0050728 Not Cancer Driver No 47 0.1253333333333333 13 4 0.0106666666666666 0
GPR31-201 GPR31 O00270 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor chr6 GO:0050728 Not Cancer Driver No 45 0.1410658307210031 14 4 0.012539184952978 0
GPS2-201 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0050728 Not Cancer Driver No 20 0.0611620795107033 320 18 0.055045871559633 0
HAMP-201 HAMP P81172 Hepcidin chr19 GO:0050728 Not Cancer Driver No 7 0.0833333333333333 4 0 0.0 4
HGF-201 HGF P14210 Hepatocyte growth factor chr7 GO:0050728 Compendium Yes 196 0.2692307692307692 43 16 0.0219780219780219 0
IER3-201 IER3 P46695 Radiation-inducible immediate-early gene IEX-1 chr6 GO:0050728 Not Cancer Driver No 4 0.0256410256410256 106 3 0.0192307692307692 0
IL10-202 IL10 P22301 Interleukin-10 chr1 GO:0050728 Not Cancer Driver No 17 0.095505617977528 23 1 0.0056179775280898 0
IL10RA-201 IL10RA Q13651 Interleukin-10 receptor subunit alpha chr11 GO:0050728 Not Cancer Driver No 64 0.1107266435986159 223 26 0.0449826989619377 7
IL13-201 IL13 P35225 Interleukin-13 chr5 GO:0050728 Not Cancer Driver No 12 0.0821917808219178 0 0 0.0 0
IL2-201 IL2 P60568 Interleukin-2 chr4 GO:0050728 Census Yes 16 0.1045751633986928 6 0 0.0 0
IL22-202 IL22 Q9GZX6 Interleukin-22 chr12 GO:0050728 Not Cancer Driver No 24 0.1340782122905028 0 0 0.0 0
IL22RA1-201 IL22RA1 Q8N6P7 Interleukin-22 receptor subunit alpha-1 chr1 GO:0050728 Not Cancer Driver No 53 0.0923344947735191 300 31 0.0540069686411149 0
IL22RA2-201 IL22RA2 Q969J5 Interleukin-22 receptor subunit alpha-2 chr6 GO:0050728 Not Cancer Driver No 21 0.0798479087452471 14 2 0.0076045627376425 0
IL2RA-203 IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0050728 Not Cancer Driver No 37 0.1360294117647058 132 19 0.0698529411764705 2
IL4-201 IL4 P05112 Interleukin-4 chr5 GO:0050728 Not Cancer Driver No 6 0.0392156862745098 0 0 0.0 0
IRGM-202 IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0050728 Not Cancer Driver No 7 0.0386740331491712 51 0 0.0 0
ISL1-201 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0050728 Not Cancer Driver No 73 0.2091690544412607 181 41 0.1174785100286533 0
KLF4-201 KLF4 O43474 Krueppel-like factor 4 chr9 GO:0050728 Census, Compendium Yes 41 0.0855949895615866 417 25 0.0521920668058455 0
KRT1-201 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0050728 Not Cancer Driver No 68 0.1055900621118012 429 40 0.062111801242236 15
LPCAT3-201 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0050728 Not Cancer Driver No 40 0.082135523613963 1 0 0.0 0
LRFN5-201 LRFN5 Q96NI6 Leucine-rich repeat and fibronectin type-III domain-containing protein 5 chr14 GO:0050728 Not Cancer Driver No 267 0.3713490959666203 194 59 0.082058414464534 0
MACIR-201 MACIR Q96GV9 Macrophage immunometabolism regulator chr5 GO:0050728 Not Cancer Driver No 23 0.1116504854368932 133 18 0.087378640776699 0
MAPK7-204 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0050728 Not Cancer Driver No 56 0.0686274509803921 490 31 0.0379901960784313 0
MEFV-201 MEFV O15553 Pyrin chr16 GO:0050728 Not Cancer Driver No 152 0.1946222791293214 402 91 0.11651728553137 43
METRNL-201 METRNL Q641Q3 Meteorin-like protein chr17 GO:0050728 Not Cancer Driver No 22 0.0707395498392283 88 5 0.0160771704180064 0
MFHAS1-201 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0050728 Not Cancer Driver No 72 0.0684410646387832 98 8 0.0076045627376425 0
MMP26-202 MMP26 Q9NRE1 Matrix metalloproteinase-26 chr11 GO:0050728 Not Cancer Driver No 58 0.2222222222222222 19 8 0.0306513409961685 0
MVK-201 MVK Q03426 Mevalonate kinase chr12 GO:0050728 Not Cancer Driver No 38 0.0959595959595959 25 0 0.0 40
NDFIP1-201 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0050728 Not Cancer Driver No 17 0.0769230769230769 45 3 0.0135746606334841 0
NFKB1-205 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0050728 Not Cancer Driver No 62 0.0640495867768595 345 30 0.03099173553719 0
NLRC3-202 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0050728 Not Cancer Driver No 136 0.1276995305164319 150 29 0.0272300469483568 0
NLRP12-201 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0050728 Not Cancer Driver No 258 0.2431668237511781 115 37 0.0348727615457115 0
NLRP3-201 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0050728 Not Cancer Driver No 287 0.2775628626692456 65 30 0.0290135396518375 34
NLRX1-202 NLRX1 Q86UT6 NLR family member X1 chr11 GO:0050728 Not Cancer Driver No 105 0.1076923076923077 95 11 0.0112820512820512 0
NR1D1-201 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0050728 Not Cancer Driver No 56 0.0912052117263843 348 39 0.0635179153094462 0
NR1D2-201 NR1D2 Q14995 Nuclear receptor subfamily 1 group D member 2 chr3 GO:0050728 Not Cancer Driver No 52 0.0898100172711571 227 16 0.0276338514680483 0
NR1H3-211 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0050728 Not Cancer Driver No 44 0.0984340044742729 147 13 0.029082774049217 0
NR1H4-209 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0050728 Not Cancer Driver No 82 0.1687242798353909 78 13 0.0267489711934156 0
NT5E-201 NT5E P21589 5'-nucleotidase chr6 GO:0050728 Not Cancer Driver No 48 0.0836236933797909 26 2 0.0034843205574912 1
OTULIN-201 OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 GO:0050728 Not Cancer Driver No 32 0.0909090909090909 97 3 0.0085227272727272 8
PBK-201 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0050728 Not Cancer Driver No 16 0.0496894409937888 92 6 0.0186335403726708 0
PGLYRP1-201 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0050728 Not Cancer Driver No 27 0.1377551020408163 4 0 0.0 0
PLA2G10-201 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0050728 Not Cancer Driver No 3 0.0181818181818181 0 0 0.0 0
PPARA-202 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0050728 Not Cancer Driver No 49 0.1047008547008547 68 9 0.0192307692307692 0
PPARD-203 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0050728 Not Cancer Driver No 51 0.1156462585034013 70 5 0.0113378684807256 0
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0050728 Census Yes 60 0.1188118811881188 44 3 0.0059405940594059 3
PRKCD-201 PRKCD Q05655 Protein kinase C delta type chr3 GO:0050728 Compendium Yes 52 0.0769230769230769 43 7 0.0103550295857988 0
PROC-201 PROC P04070 Vitamin K-dependent protein C chr2 GO:0050728 Not Cancer Driver No 44 0.0954446854663774 41 9 0.0195227765726681 35
PTGER4-201 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0050728 Not Cancer Driver No 54 0.110655737704918 118 11 0.0225409836065573 0
PTGIS-201 PTGIS Q16647 Prostacyclin synthase chr20 GO:0050728 Not Cancer Driver No 81 0.162 18 2 0.004 0
PTPN2-201 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0050728 Not Cancer Driver No 39 0.0939759036144578 120 10 0.0240963855421686 0
PYDC2-201 PYDC2 Q56P42 Pyrin domain-containing protein 2 chr3 GO:0050728 Not Cancer Driver No 19 0.1958762886597938 26 7 0.0721649484536082 0
RABGEF1-201 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0050728 Not Cancer Driver No 59 0.120162932790224 175 27 0.054989816700611 0
RB1-201 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0050728 Census, Compendium Yes 89 0.0959051724137931 282 26 0.0280172413793103 21
REG3A-201 REG3A Q06141 Regenerating islet-derived protein 3-alpha chr2 GO:0050728 Not Cancer Driver No 84 0.48 19 7 0.04 0
RORA-203 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0050728 Not Cancer Driver No 43 0.0822179732313575 181 11 0.0210325047801147 4
SAA1-201 SAA1 P0DJI8 Serum amyloid A-1 protein chr11 GO:0050728 Not Cancer Driver No 16 0.1311475409836065 25 3 0.0245901639344262 0
SELENOS-203 SELENOS Q9BQE4 Selenoprotein S chr15 GO:0050728 Not Cancer Driver No 4 0.0211640211640211 123 3 0.0158730158730158 0
SHARPIN-202 SHARPIN Q9H0F6 Sharpin chr8 GO:0050728 Not Cancer Driver No 29 0.0749354005167958 237 13 0.0335917312661498 0
SIRPA-202 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0050728 Census, Compendium Yes 60 0.119047619047619 282 41 0.0813492063492063 0
SLC39A8-201 SLC39A8 Q9C0K1 Metal cation symporter ZIP8 chr4 GO:0050728 Not Cancer Driver No 30 0.0652173913043478 22 2 0.0043478260869565 6
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0050728 Census, Compendium Yes 80 0.188235294117647 113 15 0.0352941176470588 5
SMPDL3B-202 SMPDL3B Q92485 Acid sphingomyelinase-like phosphodiesterase 3b chr1 GO:0050728 Not Cancer Driver No 43 0.0945054945054945 22 6 0.0131868131868131 0
SOCS3-201 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0050728 Not Cancer Driver No 24 0.1066666666666666 111 11 0.0488888888888888 0
SOCS5-202 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0050728 Not Cancer Driver No 63 0.1175373134328358 298 30 0.0559701492537313 0
SOD1-201 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0050728 Not Cancer Driver No 14 0.0909090909090909 94 9 0.0584415584415584 57
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0050728 Census, Compendium Yes 93 0.1207792207792207 152 16 0.0207792207792207 15
TEK-201 TEK Q02763 Angiopoietin-1 receptor chr9 GO:0050728 Not Cancer Driver No 145 0.1290035587188612 126 13 0.0115658362989323 9
TMSB4X-204 TMSB4X P62328 Thymosin beta-4 chrX GO:0050728 Census Yes 7 0.1590909090909091 45 7 0.1590909090909091 0
TNFAIP3-206 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0050728 Census, Compendium Yes 69 0.0873417721518987 231 21 0.0265822784810126 1
TNFAIP6-201 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:0050728 Not Cancer Driver No 48 0.1732851985559566 13 5 0.0180505415162454 0
TNFAIP8L2-201 TNFAIP8L2 Q6P589 Tumor necrosis factor alpha-induced protein 8-like protein 2 chr1 GO:0050728 Not Cancer Driver No 27 0.1467391304347826 0 0 0.0 0
TNFRSF1A-201 TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0050728 Not Cancer Driver No 38 0.0835164835164835 111 14 0.0307692307692307 9
TRIM45-201 TRIM45 Q9H8W5 E3 ubiquitin-protein ligase TRIM45 chr1 GO:0050728 Not Cancer Driver No 51 0.0879310344827586 59 7 0.0120689655172413 0
TRIM65-201 TRIM65 Q6PJ69 E3 ubiquitin-protein ligase TRIM65 chr17 GO:0050728 Not Cancer Driver No 40 0.0773694390715667 128 11 0.0212765957446808 0
TYRO3-201 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0050728 Not Cancer Driver No 86 0.096629213483146 197 18 0.0202247191011235 0
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0050728 Not Cancer Driver No 55 0.0690954773869346 99 7 0.0087939698492462 1
WFDC1-201 WFDC1 Q9HC57 WAP four-disulfide core domain protein 1 chr16 GO:0050728 Not Cancer Driver No 13 0.059090909090909 93 2 0.009090909090909 0
ZFP36-203 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0050728 Not Cancer Driver No 30 0.0920245398773006 263 24 0.0736196319018405 0