Total number of protein in "GO:0050729" GO term: 97
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC1-202 | ABCC1 | P33527 | Multidrug resistance-associated protein 1 | chr16 | GO:0050729 | Not Cancer Driver | No | 157 | 0.1025473546701502 | 123 | 18 | 0.0117570215545395 | 1 |
| AGT-201 | AGT | P01019 | Angiotensinogen | chr1 | GO:0050729 | Not Cancer Driver | No | 61 | 0.1281512605042016 | 33 | 3 | 0.0063025210084033 | 1 |
| AGTR1-201 | AGTR1 | P30556 | Type-1 angiotensin II receptor | chr3 | GO:0050729 | Not Cancer Driver | No | 70 | 0.1949860724233983 | 0 | 0 | 0.0 | 1 |
| AIM2-202 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0050729 | Not Cancer Driver | No | 54 | 0.1574344023323615 | 79 | 17 | 0.0495626822157434 | 0 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0050729 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
| CAMK2N1-201 | CAMK2N1 | Q7Z7J9 | Calcium/calmodulin-dependent protein kinase II inhibitor 1 | chr1 | GO:0050729 | Not Cancer Driver | No | 8 | 0.1025641025641025 | 72 | 7 | 0.0897435897435897 | 0 |
| CASP1-212 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0050729 | Not Cancer Driver | No | 54 | 0.1336633663366336 | 88 | 12 | 0.0297029702970297 | 0 |
| CASP4-203 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0050729 | Not Cancer Driver | No | 41 | 0.1087533156498673 | 103 | 11 | 0.0291777188328912 | 0 |
| CASP5-201 | CASP5 | P51878 | Caspase-5 | chr11 | GO:0050729 | Not Cancer Driver | No | 76 | 0.1751152073732718 | 61 | 13 | 0.0299539170506912 | 0 |
| CCL1-201 | CCL1 | P22362 | C-C motif chemokine 1 | chr17 | GO:0050729 | Not Cancer Driver | No | 21 | 0.21875 | 0 | 0 | 0.0 | 0 |
| CCL24-201 | CCL24 | O00175 | C-C motif chemokine 24 | chr7 | GO:0050729 | Not Cancer Driver | No | 18 | 0.1512605042016806 | 23 | 3 | 0.0252100840336134 | 0 |
| CCL3-204 | CCL3 | P10147 | C-C motif chemokine 3 | chr17 | GO:0050729 | Not Cancer Driver | No | 13 | 0.1413043478260869 | 0 | 0 | 0.0 | 0 |
| CCN4-202 | CCN4 | O95388 | CCN family member 4 | chr8 | GO:0050729 | Not Cancer Driver | No | 84 | 0.2288828337874659 | 20 | 7 | 0.0190735694822888 | 0 |
| CCR2-201 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0050729 | Not Cancer Driver | No | 56 | 0.1497326203208556 | 23 | 2 | 0.0053475935828877 | 0 |
| CD47-202 | CD47 | Q08722 | Leukocyte surface antigen CD47 | chr3 | GO:0050729 | Not Cancer Driver | No | 23 | 0.0712074303405572 | 0 | 0 | 0.0 | 0 |
| CEBPA-201 | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0050729 | Census, Compendium | Yes | 10 | 0.0279329608938547 | 343 | 10 | 0.0279329608938547 | 1 |
| CEBPB-201 | CEBPB | P17676 | CCAAT/enhancer-binding protein beta | chr20 | GO:0050729 | Not Cancer Driver | No | 2 | 0.0057971014492753 | 276 | 0 | 0.0 | 0 |
| CLOCK-211 | CLOCK | O15516 | Circadian locomoter output cycles protein kaput | chr4 | GO:0050729 | Not Cancer Driver | No | 56 | 0.0661938534278959 | 459 | 25 | 0.0295508274231678 | 0 |
| CX3CL1-201 | CX3CL1 | P78423 | Fractalkine | chr16 | GO:0050729 | Not Cancer Driver | No | 53 | 0.1335012594458438 | 259 | 36 | 0.0906801007556675 | 0 |
| DDT-202 | DDT | P30046 | D-dopachrome decarboxylase | chr22 | GO:0050729 | Not Cancer Driver | No | 2 | 0.0169491525423728 | 0 | 0 | 0.0 | 0 |
| DEFB114-201 | DEFB114 | Q30KQ6 | Beta-defensin 114 | chr6 | GO:0050729 | Not Cancer Driver | No | 23 | 0.3333333333333333 | 0 | 0 | 0.0 | 0 |
| DHX9-201 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | GO:0050729 | Compendium | Yes | 125 | 0.0984251968503937 | 332 | 30 | 0.0236220472440944 | 0 |
| ETS1-201 | ETS1 | P14921 | Protein C-ets-1 | chr11 | GO:0050729 | Not Cancer Driver | No | 47 | 0.1065759637188208 | 78 | 6 | 0.0136054421768707 | 0 |
| FABP4-201 | FABP4 | P15090 | Fatty acid-binding protein, adipocyte | chr8 | GO:0050729 | Not Cancer Driver | No | 11 | 0.0833333333333333 | 4 | 0 | 0.0 | 0 |
| FEM1A-201 | FEM1A | Q9BSK4 | Protein fem-1 homolog A | chr19 | GO:0050729 | Not Cancer Driver | No | 42 | 0.0627802690582959 | 162 | 13 | 0.0194319880418535 | 0 |
| GPR4-201 | GPR4 | P46093 | G-protein coupled receptor 4 | chr19 | GO:0050729 | Not Cancer Driver | No | 45 | 0.1243093922651933 | 44 | 5 | 0.0138121546961325 | 0 |
| GPRC5B-201 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | GO:0050729 | Not Cancer Driver | No | 72 | 0.1786600496277915 | 76 | 19 | 0.0471464019851116 | 0 |
| GPSM3-206 | GPSM3 | Q9Y4H4 | G-protein-signaling modulator 3 | chr6 | GO:0050729 | Not Cancer Driver | No | 14 | 0.0875 | 160 | 14 | 0.0875 | 0 |
| GSDMD-201 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:0050729 | Not Cancer Driver | No | 38 | 0.0785123966942148 | 156 | 14 | 0.0289256198347107 | 0 |
| HYAL2-201 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0050729 | Not Cancer Driver | No | 46 | 0.0972515856236786 | 8 | 1 | 0.0021141649048625 | 0 |
| IFI35-203 | IFI35 | P80217 | Interferon-induced 35 kDa protein | chr17 | GO:0050729 | Not Cancer Driver | No | 24 | 0.0839160839160839 | 63 | 10 | 0.0349650349650349 | 0 |
| IFNG-201 | IFNG | P01579 | Interferon gamma | chr12 | GO:0050729 | Not Cancer Driver | No | 34 | 0.2048192771084337 | 23 | 3 | 0.0180722891566265 | 0 |
| IL12B-201 | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:0050729 | Not Cancer Driver | No | 37 | 0.1128048780487804 | 42 | 1 | 0.0030487804878048 | 0 |
| IL15-202 | IL15 | P40933 | Interleukin-15 | chr4 | GO:0050729 | Not Cancer Driver | No | 20 | 0.1234567901234567 | 6 | 1 | 0.0061728395061728 | 0 |
| IL16-214 | IL16 | Q14005 | Pro-interleukin-16 | chr15 | GO:0050729 | Not Cancer Driver | No | 144 | 0.1081081081081081 | 963 | 97 | 0.0728228228228228 | 0 |
| IL17RA-201 | IL17RA | Q96F46 | Interleukin-17 receptor A | chr22 | GO:0050729 | Not Cancer Driver | No | 70 | 0.0808314087759815 | 304 | 14 | 0.0161662817551963 | 0 |
| IL18-201 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0050729 | Not Cancer Driver | No | 11 | 0.0569948186528497 | 16 | 2 | 0.0103626943005181 | 0 |
| IL1B-201 | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0050729 | Not Cancer Driver | No | 32 | 0.1189591078066914 | 16 | 2 | 0.0074349442379182 | 0 |
| IL1RL1-201 | IL1RL1 | Q01638 | Interleukin-1 receptor-like 1 | chr2 | GO:0050729 | Not Cancer Driver | No | 101 | 0.1816546762589928 | 25 | 5 | 0.0089928057553956 | 0 |
| IL2-201 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0050729 | Census | Yes | 16 | 0.1045751633986928 | 6 | 0 | 0.0 | 0 |
| IL21-203 | IL21 | Q9HBE4 | Interleukin-21 | chr4 | GO:0050729 | Not Cancer Driver | No | 28 | 0.1728395061728395 | 71 | 13 | 0.0802469135802469 | 1 |
| IL23A-201 | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:0050729 | Not Cancer Driver | No | 7 | 0.037037037037037 | 42 | 2 | 0.0105820105820105 | 0 |
| IL33-206 | IL33 | O95760 | Interleukin-33 | chr9 | GO:0050729 | Not Cancer Driver | No | 31 | 0.1148148148148148 | 47 | 5 | 0.0185185185185185 | 0 |
| LDLR-208 | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0050729 | Not Cancer Driver | No | 94 | 0.1093023255813953 | 63 | 3 | 0.0034883720930232 | 87 |
| LGALS1-201 | LGALS1 | P09382 | Galectin-1 | chr22 | GO:0050729 | Not Cancer Driver | No | 15 | 0.1111111111111111 | 0 | 0 | 0.0 | 0 |
| LGALS2-201 | LGALS2 | P05162 | Galectin-2 | chr22 | GO:0050729 | Not Cancer Driver | No | 16 | 0.1212121212121212 | 36 | 3 | 0.0227272727272727 | 0 |
| LILRA5-201 | LILRA5 | A6NI73 | Leukocyte immunoglobulin-like receptor subfamily A member 5 | chr19 | GO:0050729 | Not Cancer Driver | No | 61 | 0.2040133779264214 | 98 | 16 | 0.0535117056856187 | 0 |
| LPL-207 | LPL | P06858 | Lipoprotein lipase | chr8 | GO:0050729 | Not Cancer Driver | No | 54 | 0.1136842105263157 | 23 | 1 | 0.0021052631578947 | 59 |
| MAPK13-201 | MAPK13 | O15264 | Mitogen-activated protein kinase 13 | chr6 | GO:0050729 | Not Cancer Driver | No | 34 | 0.0931506849315068 | 50 | 11 | 0.0301369863013698 | 0 |
| MDK-203 | MDK | P21741 | Midkine | chr11 | GO:0050729 | Not Cancer Driver | No | 13 | 0.0909090909090909 | 20 | 1 | 0.0069930069930069 | 0 |
| MEFV-201 | MEFV | O15553 | Pyrin | chr16 | GO:0050729 | Not Cancer Driver | No | 152 | 0.1946222791293214 | 402 | 91 | 0.11651728553137 | 43 |
| MGST2-201 | MGST2 | Q99735 | Microsomal glutathione S-transferase 2 | chr4 | GO:0050729 | Not Cancer Driver | No | 9 | 0.0612244897959183 | 0 | 0 | 0.0 | 0 |
| NAIP-208 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0050729 | Not Cancer Driver | No | 29 | 0.0206699928724162 | 67 | 4 | 0.0028510334996436 | 0 |
| NAPEPLD-209 | NAPEPLD | Q6IQ20 | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | chr7 | GO:0050729 | Not Cancer Driver | No | 37 | 0.094147582697201 | 78 | 3 | 0.0076335877862595 | 0 |
| NFKBIA-201 | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | GO:0050729 | Compendium | Yes | 34 | 0.1072555205047318 | 102 | 10 | 0.0315457413249211 | 1 |
| NFKBIZ-202 | NFKBIZ | Q9BYH8 | NF-kappa-B inhibitor zeta | chr3 | GO:0050729 | Not Cancer Driver | No | 73 | 0.1016713091922005 | 445 | 42 | 0.0584958217270195 | 0 |
| NINJ1-201 | NINJ1 | Q92982 | Ninjurin-1 | chr9 | GO:0050729 | Not Cancer Driver | No | 14 | 0.0921052631578947 | 29 | 0 | 0.0 | 0 |
| NKG7-201 | NKG7 | Q16617 | Protein NKG7 | chr19 | GO:0050729 | Not Cancer Driver | No | 26 | 0.1575757575757575 | 0 | 0 | 0.0 | 0 |
| NLRC4-203 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0050729 | Not Cancer Driver | No | 135 | 0.1318359375 | 15 | 1 | 0.0009765625 | 3 |
| NLRP1-208 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0050729 | Not Cancer Driver | No | 169 | 0.1147318397827562 | 341 | 45 | 0.0305498981670061 | 6 |
| NLRP10-202 | NLRP10 | Q86W26 | NACHT, LRR and PYD domains-containing protein 10 | chr11 | GO:0050729 | Not Cancer Driver | No | 156 | 0.2381679389312977 | 96 | 24 | 0.0366412213740458 | 0 |
| NLRP12-201 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:0050729 | Not Cancer Driver | No | 258 | 0.2431668237511781 | 115 | 37 | 0.0348727615457115 | 0 |
| NLRP3-201 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0050729 | Not Cancer Driver | No | 287 | 0.2775628626692456 | 65 | 30 | 0.0290135396518375 | 34 |
| NLRP6-201 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0050729 | Not Cancer Driver | No | 68 | 0.0762331838565022 | 205 | 11 | 0.0123318385650224 | 0 |
| NMI-201 | NMI | Q13287 | N-myc-interactor | chr2 | GO:0050729 | Not Cancer Driver | No | 22 | 0.0716612377850162 | 107 | 8 | 0.0260586319218241 | 0 |
| OSM-201 | OSM | P13725 | Oncostatin-M | chr22 | GO:0050729 | Not Cancer Driver | No | 36 | 0.1428571428571428 | 114 | 20 | 0.0793650793650793 | 0 |
| PDCD4-201 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0050729 | Not Cancer Driver | No | 49 | 0.1044776119402985 | 188 | 25 | 0.0533049040511727 | 0 |
| PDE2A-201 | PDE2A | O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | chr11 | GO:0050729 | Not Cancer Driver | No | 82 | 0.0871413390010627 | 99 | 5 | 0.0053134962805526 | 0 |
| PLA2G2A-204 | PLA2G2A | P14555 | Phospholipase A2, membrane associated | chr1 | GO:0050729 | Not Cancer Driver | No | 21 | 0.1458333333333333 | 0 | 0 | 0.0 | 0 |
| PLA2G7-201 | PLA2G7 | Q13093 | Platelet-activating factor acetylhydrolase | chr6 | GO:0050729 | Not Cancer Driver | No | 47 | 0.1065759637188208 | 27 | 3 | 0.0068027210884353 | 2 |
| PTGER4-201 | PTGER4 | P35408 | Prostaglandin E2 receptor EP4 subtype | chr5 | GO:0050729 | Not Cancer Driver | No | 54 | 0.110655737704918 | 118 | 11 | 0.0225409836065573 | 0 |
| PYCARD-201 | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0050729 | Not Cancer Driver | No | 12 | 0.0615384615384615 | 39 | 4 | 0.0205128205128205 | 0 |
| RIPK1-201 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0050729 | Compendium | Yes | 59 | 0.0879284649776453 | 277 | 28 | 0.0417287630402384 | 1 |
| S100A12-201 | S100A12 | P80511 | Protein S100-A12 | chr1 | GO:0050729 | Not Cancer Driver | No | 11 | 0.1195652173913043 | 1 | 0 | 0.0 | 0 |
| S100A8-202 | S100A8 | P05109 | Protein S100-A8 | chr1 | GO:0050729 | Not Cancer Driver | No | 17 | 0.1827956989247312 | 8 | 4 | 0.043010752688172 | 0 |
| S100A9-201 | S100A9 | P06702 | Protein S100-A9 | chr1 | GO:0050729 | Not Cancer Driver | No | 16 | 0.1403508771929824 | 76 | 8 | 0.0701754385964912 | 0 |
| SERPINE1-201 | SERPINE1 | P05121 | Plasminogen activator inhibitor 1 | chr7 | GO:0050729 | Not Cancer Driver | No | 61 | 0.1517412935323383 | 7 | 0 | 0.0 | 0 |
| SETD4-201 | SETD4 | Q9NVD3 | SET domain-containing protein 4 | chr21 | GO:0050729 | Not Cancer Driver | No | 39 | 0.0886363636363636 | 27 | 1 | 0.0022727272727272 | 0 |
| SNCA-205 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0050729 | Not Cancer Driver | No | 15 | 0.1071428571428571 | 107 | 10 | 0.0714285714285714 | 5 |
| STAT5B-201 | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0050729 | Census, Compendium | Yes | 73 | 0.0927573062261753 | 145 | 17 | 0.0216010165184243 | 5 |
| SUCNR1-201 | SUCNR1 | Q9BXA5 | Succinate receptor 1 | chr3 | GO:0050729 | Not Cancer Driver | No | 37 | 0.1107784431137724 | 0 | 0 | 0.0 | 0 |
| TGFB1-201 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0050729 | Not Cancer Driver | No | 30 | 0.0769230769230769 | 44 | 3 | 0.0076923076923076 | 8 |
| TLR2-203 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0050729 | Not Cancer Driver | No | 84 | 0.1071428571428571 | 0 | 0 | 0.0 | 0 |
| TLR3-201 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0050729 | Not Cancer Driver | No | 89 | 0.0984513274336283 | 0 | 0 | 0.0 | 1 |
| TLR4-201 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0050729 | Not Cancer Driver | No | 253 | 0.301549463647199 | 0 | 0 | 0.0 | 0 |
| TLR7-201 | TLR7 | Q9NYK1 | Toll-like receptor 7 | chrX | GO:0050729 | Not Cancer Driver | No | 129 | 0.1229742612011439 | 14 | 1 | 0.0009532888465204 | 4 |
| TLR9-201 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0050729 | Not Cancer Driver | No | 107 | 0.1036821705426356 | 35 | 3 | 0.002906976744186 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0050729 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFRSF1A-201 | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | GO:0050729 | Not Cancer Driver | No | 38 | 0.0835164835164835 | 111 | 14 | 0.0307692307692307 | 9 |
| TNFSF4-201 | TNFSF4 | P23510 | Tumor necrosis factor ligand superfamily member 4 | chr1 | GO:0050729 | Not Cancer Driver | No | 17 | 0.0928961748633879 | 1 | 0 | 0.0 | 0 |
| TNIP1-211 | TNIP1 | Q15025 | TNFAIP3-interacting protein 1 | chr5 | GO:0050729 | Not Cancer Driver | No | 62 | 0.0974842767295597 | 628 | 60 | 0.0943396226415094 | 0 |
| TRADD-201 | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:0050729 | Not Cancer Driver | No | 18 | 0.0576923076923076 | 74 | 4 | 0.0128205128205128 | 0 |
| TRPV4-201 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0050729 | Not Cancer Driver | No | 109 | 0.1251435132032147 | 232 | 30 | 0.0344431687715269 | 38 |
| TSLP-201 | TSLP | Q969D9 | Thymic stromal lymphopoietin | chr5 | GO:0050729 | Not Cancer Driver | No | 21 | 0.1320754716981132 | 16 | 1 | 0.0062893081761006 | 0 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0050729 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |
| ZBP1-201 | ZBP1 | Q9H171 | Z-DNA-binding protein 1 | chr20 | GO:0050729 | Not Cancer Driver | No | 70 | 0.1631701631701631 | 388 | 60 | 0.1398601398601398 | 0 |
| ZP3-202 | ZP3 | P21754 | Zona pellucida sperm-binding protein 3 | chr7 | GO:0050729 | Not Cancer Driver | No | 38 | 0.0896226415094339 | 56 | 6 | 0.0141509433962264 | 1 |