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Total number of protein in "GO:0050852" GO term:  111

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0050852 Census, Compendium Yes 106 0.0938053097345132 609 53 0.0469026548672566 2
ADA-201 ADA P00813 Adenosine deaminase chr20 GO:0050852 Not Cancer Driver No 43 0.1184573002754821 45 9 0.024793388429752 22
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0050852 Not Cancer Driver No 88 0.1011494252873563 681 64 0.0735632183908046 0
BCL10-202 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0050852 Census, Compendium Yes 20 0.0858369098712446 153 14 0.0600858369098712 0
BRAF-220 BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0050852 Census, Compendium Yes 755 0.9856396866840732 311 30 0.0391644908616188 35
BTK-201 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0050852 Census, Compendium Yes 109 0.165402124430956 114 21 0.0318664643399089 83
BTN1A1-202 BTN1A1 Q13410 Butyrophilin subfamily 1 member A1 chr6 GO:0050852 Not Cancer Driver No 84 0.1596958174904943 90 11 0.0209125475285171 0
BTN2A1-201 BTN2A1 Q7KYR7 Butyrophilin subfamily 2 member A1 chr6 GO:0050852 Not Cancer Driver No 57 0.1081593927893738 38 5 0.0094876660341555 0
BTN2A2-202 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0050852 Not Cancer Driver No 58 0.1108986615678776 24 2 0.0038240917782026 0
BTN3A1-202 BTN3A1 O00481 Butyrophilin subfamily 3 member A1 chr6 GO:0050852 Not Cancer Driver No 59 0.1150097465886939 72 13 0.0253411306042884 0
BTN3A2-202 BTN3A2 P78410 Butyrophilin subfamily 3 member A2 chr6 GO:0050852 Not Cancer Driver No 42 0.1257485029940119 47 3 0.0089820359281437 0
BTN3A3-201 BTN3A3 O00478 Butyrophilin subfamily 3 member A3 chr6 GO:0050852 Not Cancer Driver No 67 0.1147260273972602 143 21 0.035958904109589 0
BTNL2-203 BTNL2 Q9UIR0 Butyrophilin-like protein 2 chr6 GO:0050852 Not Cancer Driver No 52 0.1078838174273859 75 9 0.0186721991701244 0
BTNL3-201 BTNL3 Q6UXE8 Butyrophilin-like protein 3 chr5 GO:0050852 Not Cancer Driver No 71 0.1523605150214592 50 10 0.0214592274678111 0
BTNL8-202 BTNL8 Q6UX41 Butyrophilin-like protein 8 chr5 GO:0050852 Not Cancer Driver No 99 0.198 86 17 0.034 0
BTNL9-201 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 GO:0050852 Not Cancer Driver No 53 0.0990654205607476 87 3 0.005607476635514 0
CACNB3-201 CACNB3 P54284 Voltage-dependent L-type calcium channel subunit beta-3 chr12 GO:0050852 Not Cancer Driver No 38 0.0785123966942148 258 20 0.0413223140495867 0
CACNB4-210 CACNB4 O00305 Voltage-dependent L-type calcium channel subunit beta-4 chr2 GO:0050852 Not Cancer Driver No 59 0.1134615384615384 295 38 0.073076923076923 1
CBLB-201 CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0050852 Census Yes 126 0.1283095723014256 565 77 0.0784114052953156 0
CD247-201 CD247 P20963 T-cell surface glycoprotein CD3 zeta chain chr1 GO:0050852 Not Cancer Driver No 20 0.1219512195121951 92 14 0.0853658536585365 0
CD276-202 CD276 Q5ZPR3 CD276 antigen chr15 GO:0050852 Not Cancer Driver No 47 0.0880149812734082 140 8 0.0149812734082397 0
CD28-201 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0050852 Census Yes 26 0.1181818181818181 18 6 0.0272727272727272 0
CD2AP-201 CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0050852 Not Cancer Driver No 51 0.0798122065727699 458 38 0.0594679186228482 0
CD3D-201 CD3D P04234 T-cell surface glycoprotein CD3 delta chain chr11 GO:0050852 Not Cancer Driver No 19 0.1111111111111111 2 1 0.0058479532163742 0
CD3E-201 CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0050852 Not Cancer Driver No 16 0.0772946859903381 72 6 0.0289855072463768 0
CD3G-206 CD3G P09693 T-cell surface glycoprotein CD3 gamma chain chr11 GO:0050852 Not Cancer Driver No 15 0.0824175824175824 49 5 0.0274725274725274 0
CD8A-201 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 GO:0050852 Not Cancer Driver No 27 0.1148936170212766 28 2 0.0085106382978723 1
CD8B-203 CD8B P10966 T-cell surface glycoprotein CD8 beta chain chr2 GO:0050852 Not Cancer Driver No 33 0.1571428571428571 10 0 0.0 0
CRKL-201 CRKL P46109 Crk-like protein chr22 GO:0050852 Not Cancer Driver No 24 0.0792079207920792 160 17 0.0561056105610561 0
CSK-201 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0050852 Not Cancer Driver No 37 0.0822222222222222 18 1 0.0022222222222222 0
CTLA4-204 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0050852 Not Cancer Driver No 28 0.1255605381165919 3 0 0.0 1
DENND1B-211 DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0050852 Not Cancer Driver No 29 0.0374193548387096 301 0 0.0 0
EIF2B1-201 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 GO:0050852 Not Cancer Driver No 32 0.1049180327868852 0 0 0.0 2
EIF2B2-201 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0050852 Not Cancer Driver No 34 0.0968660968660968 83 9 0.0256410256410256 9
EIF2B3-201 EIF2B3 Q9NR50 Translation initiation factor eIF-2B subunit gamma chr1 GO:0050852 Not Cancer Driver No 38 0.084070796460177 28 7 0.0154867256637168 5
EIF2B4-201 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 GO:0050852 Not Cancer Driver No 49 0.0936902485659655 212 26 0.0497131931166348 7
EIF2B5-226 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 GO:0050852 Not Cancer Driver No 49 0.0679611650485436 179 9 0.0124826629680998 21
ENST00000558468 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0050852 Not Cancer Driver No 116 0.1082089552238805 320 38 0.0354477611940298 0
ERMAP-203 ERMAP Q96PL5 Erythroid membrane-associated protein chr1 GO:0050852 Not Cancer Driver No 40 0.0842105263157894 48 3 0.0063157894736842 0
FCHO1-215 FCHO1 O14526 F-BAR domain only protein 1 chr19 GO:0050852 Not Cancer Driver No 99 0.1113610798650168 536 58 0.0652418447694038 2
FOSL2-201 FOSL2 P15408 Fos-related antigen 2 chr2 GO:0050852 Not Cancer Driver No 39 0.1196319018404908 323 39 0.1196319018404908 0
FOXP3-203 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0050852 Not Cancer Driver No 29 0.0672853828306264 186 13 0.0301624129930394 10
FYB1-209 FYB1 O15117 FYN-binding protein 1 chr5 GO:0050852 Not Cancer Driver No 118 0.1507024265644955 689 107 0.1366538952745849 0
FYB2-201 FYB2 Q5VWT5 FYN-binding protein 2 chr1 GO:0050852 Not Cancer Driver No 120 0.1648351648351648 550 100 0.1373626373626373 0
FYN-202 FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0050852 Not Cancer Driver No 64 0.1191806331471136 71 11 0.0204841713221601 0
GATA3-201 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0050852 Census, Compendium Yes 99 0.2234762979683973 368 79 0.1783295711060948 2
HHLA2-206 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0050852 Not Cancer Driver No 65 0.1570048309178744 58 9 0.0217391304347826 0
HLA-A-203 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0050852 Census, Compendium Yes 38 0.1041095890410958 125 16 0.0438356164383561 0
HLA-DPB1-211 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 GO:0050852 Not Cancer Driver No 14 0.0542635658914728 39 4 0.0155038759689922 0
HLA-DQB1-205 HLA-DQB1 P01920 HLA class II histocompatibility antigen, DQ beta 1 chain chr6 GO:0050852 Not Cancer Driver No 17 0.0651340996168582 25 1 0.003831417624521 0
HLA-DRB1-201 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0050852 Not Cancer Driver No 11 0.0413533834586466 12 0 0.0 0
HRAS-201 HRAS P01112 GTPase HRas chr11 GO:0050852 Census, Compendium Yes 129 0.6825396825396826 16 2 0.0105820105820105 10
ICOSLG-204 ICOSLG O75144 ICOS ligand chr21 GO:0050852 Not Cancer Driver No 20 0.0662251655629139 29 2 0.0066225165562913 0
IKBKB-216 IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0050852 Census, Compendium Yes 83 0.1097883597883597 211 22 0.0291005291005291 1
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0050852 Not Cancer Driver No 5 0.0119331742243436 301 4 0.0095465393794749 21
INPP5D-204 INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0050852 Not Cancer Driver No 140 0.1177460050462573 579 75 0.0630782169890664 0
ITK-201 ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0050852 Census Yes 106 0.1709677419354838 43 9 0.014516129032258 1
KHDRBS1-202 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 GO:0050852 Not Cancer Driver No 42 0.0948081264108352 362 37 0.0835214446952596 0
LAT-201 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0050852 Not Cancer Driver No 20 0.0763358778625954 213 19 0.0725190839694656 0
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0050852 Census Yes 76 0.1493123772102161 95 12 0.0235756385068762 1
LCP2-201 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 GO:0050852 Not Cancer Driver No 75 0.1407129455909943 393 57 0.1069418386491557 0
LIME1-201 LIME1 Q9H400 Lck-interacting transmembrane adapter 1 chr20 GO:0050852 Not Cancer Driver No 20 0.0677966101694915 193 14 0.047457627118644 0
MALT1-208 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0050852 Census, Compendium Yes 55 0.0667475728155339 139 9 0.0109223300970873 1
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0050852 Not Cancer Driver No 74 0.1221122112211221 333 42 0.0693069306930693 6
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0050852 Census, Compendium Yes 52 0.1444444444444444 2 0 0.0 6
MOG-221 MOG Q16653 Myelin-oligodendrocyte glycoprotein chr6 GO:0050852 Not Cancer Driver No 38 0.1538461538461538 13 2 0.0080971659919028 1
NFKBID-201 NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0050852 Not Cancer Driver No 41 0.1309904153354632 125 16 0.0511182108626198 0
NFKBIZ-202 NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0050852 Not Cancer Driver No 73 0.1016713091922005 445 42 0.0584958217270195 0
PDE4B-202 PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0050852 Not Cancer Driver No 91 0.123641304347826 365 32 0.0434782608695652 0
PDE4D-203 PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0050852 Not Cancer Driver No 65 0.0803461063040791 464 38 0.0469715698393077 12
PIK3CA-201 PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0050852 Census, Compendium Yes 1425 1.3342696629213484 38 9 0.0084269662921348 44
PIK3CD-202 PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0050852 Not Cancer Driver No 116 0.1111111111111111 61 8 0.0076628352490421 1
PLCG1-202 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0050852 Census, Compendium Yes 129 0.1 187 15 0.0116279069767441 0
PLCG2-206 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0050852 Not Cancer Driver No 183 0.1446640316205533 144 18 0.0142292490118577 1
PRAM1-201 PRAM1 Q96QH2 PML-RARA-regulated adapter molecule 1 chr19 GO:0050852 Not Cancer Driver No 82 0.1223880597014925 637 82 0.1223880597014925 0
PRKD2-201 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0050852 Compendium Yes 89 0.1013667425968109 247 26 0.0296127562642369 0
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 GO:0050852 Not Cancer Driver No 43 0.0920770877944325 134 18 0.038543897216274 69
PTPN22-201 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0050852 Not Cancer Driver No 107 0.1325898389095415 344 44 0.0545229244114002 4
PTPN6-201 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0050852 Census, Compendium Yes 52 0.0873949579831932 194 20 0.0336134453781512 0
PTPRC-209 PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0050852 Census, Compendium Yes 257 0.1967840735068912 462 91 0.0696784073506891 0
PTPRJ-201 PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0050852 Not Cancer Driver No 130 0.0972326103216155 403 39 0.0291697830964846 0
RBCK1-202 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 GO:0050852 Not Cancer Driver No 42 0.0823529411764705 141 14 0.0274509803921568 2
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 GO:0050852 Not Cancer Driver No 114 0.1006178287731685 798 81 0.0714916151809355 0
RC3H2-202 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0050852 Not Cancer Driver No 99 0.0831234256926952 704 62 0.0520570948782535 0
RFTN1-201 RFTN1 Q14699 Raftlin chr3 GO:0050852 Not Cancer Driver No 64 0.1107266435986159 321 32 0.0553633217993079 0
RIPK2-201 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0050852 Not Cancer Driver No 43 0.0796296296296296 143 14 0.0259259259259259 0
RNF31-201 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0050852 Not Cancer Driver No 116 0.1082089552238805 319 38 0.0354477611940298 0
SHB-201 SHB Q15464 SH2 domain-containing adapter protein B chr9 GO:0050852 Not Cancer Driver No 42 0.0825147347740668 338 29 0.0569744597249508 0
SKAP1-201 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0050852 Not Cancer Driver No 58 0.1615598885793872 132 24 0.0668523676880222 0
SLC39A6-201 SLC39A6 Q13433 Zinc transporter ZIP6 chr18 GO:0050852 Not Cancer Driver No 63 0.0834437086092715 362 28 0.0370860927152317 0
SPPL3-201 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:0050852 Not Cancer Driver No 39 0.1015625 23 0 0.0 0
STK11-201 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0050852 Census, Compendium Yes 63 0.1454965357967667 135 12 0.0277136258660508 9
STOML2-201 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0050852 Not Cancer Driver No 27 0.0758426966292134 117 6 0.0168539325842696 0
TEC-201 TEC P42680 Tyrosine-protein kinase Tec chr4 GO:0050852 Census, Compendium Yes 66 0.1045958795562599 57 11 0.0174326465927099 0
THEMIS-201 THEMIS Q8N1K5 Protein THEMIS chr6 GO:0050852 Not Cancer Driver No 169 0.2636505460218408 111 33 0.0514820592823713 0
THEMIS2-202 THEMIS2 Q5TEJ8 Protein THEMIS2 chr1 GO:0050852 Not Cancer Driver No 42 0.0653188180404354 212 17 0.0264385692068429 0
THY1-201 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0050852 Not Cancer Driver No 23 0.1428571428571428 5 0 0.0 0
TNFRSF21-201 TNFRSF21 O75509 Tumor necrosis factor receptor superfamily member 21 chr6 GO:0050852 Not Cancer Driver No 72 0.1099236641221374 280 38 0.0580152671755725 0
TRAC-201 TRAC P01848 T cell receptor alpha chain constant chr14 GO:0050852 Not Cancer Driver No 0 0.0 0 0 0.0 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0050852 Not Cancer Driver No 51 0.0977011494252873 62 5 0.0095785440613026 0
TRBC1-201 TRBC1 P01850 T cell receptor beta constant 1 chr7 GO:0050852 Not Cancer Driver No 0 0.0 0 0 0.0 0
TRBC2-201 TRBC2 A0A5B9 T cell receptor beta constant 2 chr7 GO:0050852 Not Cancer Driver No 0 0.0 0 0 0.0 0
TRDC-201 TRDC B7Z8K6 T cell receptor delta constant chr14 GO:0050852 Not Cancer Driver No 0 0.0 0 0 0.0 0
TRGC1-201 TRGC1 P0CF51 T cell receptor gamma constant 1 chr7 GO:0050852 Not Cancer Driver No 0 0.0 0 0 0.0 0
TRGC2-201 TRGC2 P03986 T cell receptor gamma constant 2 chr7 GO:0050852 Not Cancer Driver No 0 0.0 0 0 0.0 0
TXK-201 TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0050852 Not Cancer Driver No 60 0.1138519924098671 61 4 0.0075901328273244 0
UBE2N-201 UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0050852 Not Cancer Driver No 19 0.125 24 1 0.006578947368421 0
VTCN1-203 VTCN1 Q7Z7D3 V-set domain-containing T-cell activation inhibitor 1 chr1 GO:0050852 Not Cancer Driver No 32 0.1134751773049645 3 2 0.0070921985815602 0
WNK1-201 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0050852 Not Cancer Driver No 129 0.0541561712846347 1948 115 0.0482787573467674 0
ZAP70-201 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0050852 Not Cancer Driver No 90 0.1453957996768982 119 13 0.0210016155088853 7
ZC3H12A-201 ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0050852 Not Cancer Driver No 77 0.1285475792988314 397 38 0.0634390651085141 0