Total number of protein in "GO:0051402" GO term: 80
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AARS1-201 | AARS1 | P49588 | Alanine--tRNA ligase, cytoplasmic | chr16 | GO:0051402 | Not Cancer Driver | No | 69 | 0.0712809917355371 | 141 | 11 | 0.0113636363636363 | 5 |
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0051402 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| ADNP-205 | ADNP | Q9H2P0 | Activity-dependent neuroprotector homeobox protein | chr20 | GO:0051402 | Not Cancer Driver | No | 96 | 0.087114337568058 | 615 | 52 | 0.0471869328493647 | 0 |
| AGTR2-201 | AGTR2 | P50052 | Type-2 angiotensin II receptor | chrX | GO:0051402 | Not Cancer Driver | No | 67 | 0.1845730027548209 | 0 | 0 | 0.0 | 0 |
| AIFM1-201 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0051402 | Not Cancer Driver | No | 61 | 0.099510603588907 | 166 | 20 | 0.032626427406199 | 10 |
| ANGPT1-202 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0051402 | Not Cancer Driver | No | 100 | 0.2008032128514056 | 131 | 10 | 0.0200803212851405 | 1 |
| APAF1-210 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0051402 | Not Cancer Driver | No | 91 | 0.0729166666666666 | 17 | 1 | 0.000801282051282 | 0 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0051402 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0051402 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| ATN1-202 | ATN1 | P54259 | Atrophin-1 | chr12 | GO:0051402 | Not Cancer Driver | No | 111 | 0.0932773109243697 | 1176 | 109 | 0.0915966386554621 | 5 |
| AXL-201 | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0051402 | Not Cancer Driver | No | 131 | 0.1465324384787472 | 342 | 51 | 0.0570469798657718 | 0 |
| BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0051402 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
| BCL2L1-201 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0051402 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 55 | 2 | 0.0085836909871244 | 0 |
| BID-211 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0051402 | Not Cancer Driver | No | 17 | 0.0871794871794871 | 75 | 5 | 0.0256410256410256 | 0 |
| BNIP3-201 | BNIP3 | Q12983 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | chr10 | GO:0051402 | Not Cancer Driver | No | 16 | 0.0824742268041237 | 131 | 11 | 0.056701030927835 | 0 |
| BOK-201 | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0051402 | Not Cancer Driver | No | 5 | 0.0235849056603773 | 0 | 0 | 0.0 | 0 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0051402 | Census | Yes | 19 | 0.0685920577617328 | 64 | 1 | 0.003610108303249 | 0 |
| CASP7-203 | CASP7 | P55210 | Caspase-7 | chr10 | GO:0051402 | Not Cancer Driver | No | 28 | 0.0924092409240924 | 75 | 7 | 0.0231023102310231 | 0 |
| CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0051402 | Census | Yes | 26 | 0.0625 | 71 | 7 | 0.016826923076923 | 0 |
| CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0051402 | Not Cancer Driver | No | 38 | 0.1301369863013698 | 5 | 0 | 0.0 | 0 |
| CIT-201 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | GO:0051402 | Not Cancer Driver | No | 196 | 0.0966946225949679 | 1020 | 116 | 0.0572274296990626 | 3 |
| COL6A1-201 | COL6A1 | P12109 | Collagen alpha-1(VI) chain | chr21 | GO:0051402 | Not Cancer Driver | No | 68 | 0.0661478599221789 | 436 | 23 | 0.0223735408560311 | 12 |
| COL6A2-201 | COL6A2 | P12110 | Collagen alpha-2(VI) chain | chr21 | GO:0051402 | Not Cancer Driver | No | 176 | 0.1727183513248282 | 465 | 77 | 0.0755642787046123 | 10 |
| COL6A3-201 | COL6A3 | P12111 | Collagen alpha-3(VI) chain | chr2 | GO:0051402 | Not Cancer Driver | No | 379 | 0.1192949323260938 | 697 | 48 | 0.0151085930122757 | 14 |
| CORO1A-201 | CORO1A | P31146 | Coronin-1A | chr16 | GO:0051402 | Not Cancer Driver | No | 39 | 0.0845986984815618 | 126 | 11 | 0.0238611713665943 | 1 |
| CRH-201 | CRH | P06850 | Corticoliberin | chr8 | GO:0051402 | Not Cancer Driver | No | 9 | 0.0459183673469387 | 131 | 9 | 0.0459183673469387 | 0 |
| DIABLO-207 | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0051402 | Not Cancer Driver | No | 20 | 0.0836820083682008 | 54 | 2 | 0.00836820083682 | 1 |
| DLX1-203 | DLX1 | P56177 | Homeobox protein DLX-1 | chr2 | GO:0051402 | Not Cancer Driver | No | 21 | 0.0823529411764705 | 183 | 17 | 0.0666666666666666 | 0 |
| DNAJC5-201 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | GO:0051402 | Not Cancer Driver | No | 19 | 0.0959595959595959 | 46 | 5 | 0.0252525252525252 | 1 |
| EPHA7-202 | EPHA7 | Q15375 | Ephrin type-A receptor 7 | chr6 | GO:0051402 | Census, Compendium | Yes | 226 | 0.2264529058116232 | 71 | 10 | 0.0100200400801603 | 0 |
| ERBB3-201 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0051402 | Census, Compendium | Yes | 265 | 0.1974664679582712 | 398 | 59 | 0.0439642324888226 | 3 |
| FAIM2-201 | FAIM2 | Q9BWQ8 | Protein lifeguard 2 | chr12 | GO:0051402 | Not Cancer Driver | No | 29 | 0.0917721518987341 | 55 | 8 | 0.0253164556962025 | 0 |
| FAM162A-203 | FAM162A | Q96A26 | Protein FAM162A | chr3 | GO:0051402 | Not Cancer Driver | No | 10 | 0.0649350649350649 | 53 | 4 | 0.0259740259740259 | 0 |
| FGF8-202 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | GO:0051402 | Not Cancer Driver | No | 27 | 0.1158798283261802 | 79 | 8 | 0.0343347639484978 | 6 |
| GAPDH-201 | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | GO:0051402 | Not Cancer Driver | No | 36 | 0.1074626865671641 | 24 | 3 | 0.008955223880597 | 0 |
| GBA1-202 | GBA1 | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0051402 | Not Cancer Driver | No | 60 | 0.1119402985074626 | 38 | 6 | 0.0111940298507462 | 157 |
| GPX1-202 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0051402 | Not Cancer Driver | No | 22 | 0.1083743842364532 | 12 | 3 | 0.0147783251231527 | 0 |
| GRIK2-202 | GRIK2 | Q13002 | Glutamate receptor ionotropic, kainate 2 | chr6 | GO:0051402 | Not Cancer Driver | No | 226 | 0.2488986784140969 | 57 | 15 | 0.0165198237885462 | 3 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0051402 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HIPK2-202 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0051402 | Not Cancer Driver | No | 124 | 0.1035058430717863 | 686 | 76 | 0.0634390651085141 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | GO:0051402 | Census, Compendium | Yes | 129 | 0.6825396825396826 | 16 | 2 | 0.0105820105820105 | 10 |
| HTRA2-201 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0051402 | Compendium | Yes | 33 | 0.0720524017467248 | 127 | 7 | 0.0152838427947598 | 2 |
| KCNQ3-201 | KCNQ3 | O43525 | Potassium voltage-gated channel subfamily KQT member 3 | chr8 | GO:0051402 | Not Cancer Driver | No | 209 | 0.2396788990825688 | 414 | 97 | 0.1112385321100917 | 3 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | GO:0051402 | Census, Compendium | Yes | 771 | 4.079365079365079 | 7 | 2 | 0.0105820105820105 | 22 |
| LIG4-202 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0051402 | Not Cancer Driver | No | 103 | 0.1130625686059275 | 63 | 10 | 0.0109769484083424 | 2 |
| MAP3K5-201 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0051402 | Not Cancer Driver | No | 146 | 0.106259097525473 | 244 | 23 | 0.0167394468704512 | 0 |
| NAE1-201 | NAE1 | Q13564 | NEDD8-activating enzyme E1 regulatory subunit | chr16 | GO:0051402 | Not Cancer Driver | No | 27 | 0.0505617977528089 | 69 | 2 | 0.0037453183520599 | 0 |
| NCSTN-201 | NCSTN | Q92542 | Nicastrin | chr1 | GO:0051402 | Not Cancer Driver | No | 69 | 0.0973201692524682 | 72 | 10 | 0.0141043723554301 | 1 |
| NDP-202 | NDP | Q00604 | Norrin | chrX | GO:0051402 | Not Cancer Driver | No | 11 | 0.0827067669172932 | 0 | 0 | 0.0 | 45 |
| NES-201 | NES | P48681 | Nestin | chr1 | GO:0051402 | Not Cancer Driver | No | 203 | 0.1252313386798272 | 1485 | 189 | 0.1165946946329426 | 0 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0051402 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NFATC4-201 | NFATC4 | Q14934 | Nuclear factor of activated T-cells, cytoplasmic 4 | chr14 | GO:0051402 | Not Cancer Driver | No | 122 | 0.1352549889135255 | 685 | 92 | 0.1019955654101995 | 0 |
| NGFR-201 | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | GO:0051402 | Not Cancer Driver | No | 46 | 0.1077283372365339 | 174 | 23 | 0.0538641686182669 | 0 |
| NLRP1-208 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0051402 | Not Cancer Driver | No | 169 | 0.1147318397827562 | 341 | 45 | 0.0305498981670061 | 6 |
| NPR2-201 | NPR2 | P20594 | Atrial natriuretic peptide receptor 2 | chr9 | GO:0051402 | Not Cancer Driver | No | 106 | 0.1012416427889207 | 91 | 9 | 0.0085959885386819 | 20 |
| NR4A2-201 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0051402 | Not Cancer Driver | No | 84 | 0.1404682274247491 | 262 | 32 | 0.0535117056856187 | 3 |
| NTRK1-206 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0051402 | Census, Compendium | Yes | 133 | 0.1670854271356784 | 57 | 8 | 0.0100502512562814 | 23 |
| OXR1-205 | OXR1 | Q8N573 | Oxidation resistance protein 1 | chr8 | GO:0051402 | Not Cancer Driver | No | 87 | 0.0995423340961098 | 545 | 56 | 0.0640732265446224 | 0 |
| PIGT-202 | PIGT | Q969N2 | GPI transamidase component PIG-T | chr20 | GO:0051402 | Not Cancer Driver | No | 42 | 0.0726643598615917 | 36 | 6 | 0.0103806228373702 | 1 |
| POLB-201 | POLB | P06746 | DNA polymerase beta | chr8 | GO:0051402 | Not Cancer Driver | No | 32 | 0.0955223880597015 | 87 | 8 | 0.0238805970149253 | 0 |
| POU4F1-201 | POU4F1 | Q01851 | POU domain, class 4, transcription factor 1 | chr13 | GO:0051402 | Not Cancer Driver | No | 33 | 0.0787589498806682 | 274 | 20 | 0.0477326968973747 | 1 |
| POU4F3-201 | POU4F3 | Q15319 | POU domain, class 4, transcription factor 3 | chr5 | GO:0051402 | Not Cancer Driver | No | 49 | 0.1449704142011834 | 199 | 32 | 0.0946745562130177 | 10 |
| PPARGC1A-201 | PPARGC1A | Q9UBK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | chr4 | GO:0051402 | Not Cancer Driver | No | 91 | 0.1140350877192982 | 613 | 85 | 0.106516290726817 | 0 |
| PSEN1-201 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0051402 | Not Cancer Driver | No | 43 | 0.0920770877944325 | 134 | 18 | 0.038543897216274 | 69 |
| RB1-201 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0051402 | Census, Compendium | Yes | 89 | 0.0959051724137931 | 282 | 26 | 0.0280172413793103 | 21 |
| SCN2A-202 | SCN2A | Q99250 | Sodium channel protein type 2 subunit alpha | chr2 | GO:0051402 | Not Cancer Driver | No | 363 | 0.1810473815461346 | 436 | 92 | 0.0458852867830423 | 73 |
| SIAH1-203 | SIAH1 | Q8IUQ4 | E3 ubiquitin-protein ligase SIAH1 | chr16 | GO:0051402 | Not Cancer Driver | No | 22 | 0.0780141843971631 | 28 | 2 | 0.0070921985815602 | 5 |
| SNCA-205 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0051402 | Not Cancer Driver | No | 15 | 0.1071428571428571 | 107 | 10 | 0.0714285714285714 | 5 |
| SNCB-202 | SNCB | Q16143 | Beta-synuclein | chr5 | GO:0051402 | Not Cancer Driver | No | 18 | 0.1343283582089552 | 113 | 16 | 0.1194029850746268 | 0 |
| STXBP1-201 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | GO:0051402 | Not Cancer Driver | No | 61 | 0.1026936026936027 | 112 | 13 | 0.0218855218855218 | 19 |
| SYNGAP1-229 | SYNGAP1 | Q96PV0 | Ras/Rap GTPase-activating protein SynGAP | chr6 | GO:0051402 | Not Cancer Driver | No | 113 | 0.0841399851079672 | 833 | 66 | 0.0491437081161578 | 4 |
| TFAP2B-202 | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0051402 | Not Cancer Driver | No | 77 | 0.1673913043478261 | 306 | 55 | 0.1195652173913043 | 5 |
| TNFRSF21-201 | TNFRSF21 | O75509 | Tumor necrosis factor receptor superfamily member 21 | chr6 | GO:0051402 | Not Cancer Driver | No | 72 | 0.1099236641221374 | 280 | 38 | 0.0580152671755725 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0051402 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0051402 | Census, Compendium | Yes | 198 | 0.2911764705882353 | 398 | 120 | 0.1764705882352941 | 21 |
| TRPC5-201 | TRPC5 | Q9UL62 | Short transient receptor potential channel 5 | chrX | GO:0051402 | Not Cancer Driver | No | 195 | 0.2004110996916752 | 148 | 23 | 0.0236382322713257 | 0 |
| TUBA1A-202 | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | GO:0051402 | Not Cancer Driver | No | 45 | 0.0997782705099778 | 52 | 6 | 0.0133037694013303 | 6 |
| TYRO3-201 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0051402 | Not Cancer Driver | No | 86 | 0.096629213483146 | 197 | 18 | 0.0202247191011235 | 0 |
| XIAP-202 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0051402 | Not Cancer Driver | No | 61 | 0.1227364185110664 | 55 | 2 | 0.0040241448692152 | 0 |
| ZNF212-201 | ZNF212 | Q9UDV6 | Zinc finger protein 212 | chr7 | GO:0051402 | Not Cancer Driver | No | 45 | 0.0909090909090909 | 289 | 19 | 0.0383838383838383 | 0 |