Total number of protein in "GO:0051865" GO term: 69
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMFR-201 | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | GO:0051865 | Not Cancer Driver | No | 49 | 0.0762052877138413 | 229 | 22 | 0.0342146189735614 | 0 |
ASB4-202 | ASB4 | Q9Y574 | Ankyrin repeat and SOCS box protein 4 | chr7 | GO:0051865 | Not Cancer Driver | No | 60 | 0.1408450704225352 | 19 | 1 | 0.0023474178403755 | 0 |
BFAR-201 | BFAR | Q9NZS9 | Bifunctional apoptosis regulator | chr16 | GO:0051865 | Not Cancer Driver | No | 50 | 0.1111111111111111 | 30 | 1 | 0.0022222222222222 | 0 |
BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0051865 | Census, Compendium | Yes | 167 | 0.0896403650026838 | 1466 | 127 | 0.0681696188942565 | 34 |
CBL-201 | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0051865 | Census, Compendium | Yes | 84 | 0.0927152317880794 | 513 | 44 | 0.0485651214128035 | 4 |
CNOT4-214 | CNOT4 | O95628 | CCR4-NOT transcription complex subunit 4 | chr7 | GO:0051865 | Not Cancer Driver | No | 46 | 0.08 | 360 | 24 | 0.0417391304347826 | 0 |
CUL3-201 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0051865 | Census, Compendium | Yes | 98 | 0.1276041666666666 | 168 | 18 | 0.0234375 | 3 |
DDB2-201 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | GO:0051865 | Census, Compendium | Yes | 35 | 0.081967213114754 | 71 | 5 | 0.0117096018735363 | 2 |
DTX3L-201 | DTX3L | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | chr3 | GO:0051865 | Not Cancer Driver | No | 60 | 0.081081081081081 | 260 | 19 | 0.0256756756756756 | 0 |
ENST00000645271 | LOC122513141 | A0A2R8Y4M4 | RING-type domain-containing protein | chr9 | GO:0051865 | Not Cancer Driver | No | 0 | 0.0 | 47 | 0 | 0.0 | 0 |
ERCC8-218 | ERCC8 | Q13216 | DNA excision repair protein ERCC-8 | chr5 | GO:0051865 | Not Cancer Driver | No | 17 | 0.0429292929292929 | 55 | 7 | 0.0176767676767676 | 6 |
ITCH-201 | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0051865 | Not Cancer Driver | No | 75 | 0.0830564784053156 | 335 | 33 | 0.0365448504983388 | 0 |
KLHL24-201 | KLHL24 | Q6TFL4 | Kelch-like protein 24 | chr3 | GO:0051865 | Not Cancer Driver | No | 77 | 0.1283333333333333 | 17 | 4 | 0.0066666666666666 | 1 |
LRSAM1-201 | LRSAM1 | Q6UWE0 | E3 ubiquitin-protein ligase LRSAM1 | chr9 | GO:0051865 | Not Cancer Driver | No | 71 | 0.0982019363762102 | 240 | 24 | 0.0331950207468879 | 1 |
LTN1-201 | LTN1 | O94822 | E3 ubiquitin-protein ligase listerin | chr21 | GO:0051865 | Not Cancer Driver | No | 139 | 0.0787089467723669 | 125 | 15 | 0.008493771234428 | 0 |
MARCHF5-201 | MARCHF5 | Q9NX47 | E3 ubiquitin-protein ligase MARCHF5 | chr10 | GO:0051865 | Not Cancer Driver | No | 20 | 0.0719424460431654 | 0 | 0 | 0.0 | 0 |
MARCHF7-202 | MARCHF7 | Q9H992 | E3 ubiquitin-protein ligase MARCHF7 | chr2 | GO:0051865 | Not Cancer Driver | No | 59 | 0.0838068181818181 | 557 | 46 | 0.065340909090909 | 0 |
MDM2-224 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0051865 | Census, Compendium | Yes | 39 | 0.0794297352342158 | 298 | 24 | 0.0488798370672097 | 0 |
NFX1-203 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | GO:0051865 | Not Cancer Driver | No | 89 | 0.0794642857142857 | 492 | 28 | 0.025 | 0 |
OBI1-201 | OBI1 | Q5W0B1 | ORC ubiquitin ligase 1 | chr13 | GO:0051865 | Not Cancer Driver | No | 64 | 0.0881542699724518 | 486 | 43 | 0.059228650137741 | 0 |
PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0051865 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
RAD18-201 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | GO:0051865 | Not Cancer Driver | No | 42 | 0.0848484848484848 | 330 | 31 | 0.0626262626262626 | 0 |
RAG1-201 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0051865 | Not Cancer Driver | No | 161 | 0.1543624161073825 | 209 | 34 | 0.0325982742090124 | 35 |
RNF10-201 | RNF10 | Q8N5U6 | E3 ubiquitin-protein ligase RNF10 | chr12 | GO:0051865 | Not Cancer Driver | No | 85 | 0.1048088779284833 | 456 | 52 | 0.064118372379778 | 0 |
RNF11-201 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | GO:0051865 | Not Cancer Driver | No | 11 | 0.0714285714285714 | 78 | 6 | 0.0389610389610389 | 0 |
RNF112-201 | RNF112 | Q9ULX5 | RING finger protein 112 | chr17 | GO:0051865 | Not Cancer Driver | No | 71 | 0.1125198098256735 | 169 | 22 | 0.0348652931854199 | 0 |
RNF115-202 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 | chr1 | GO:0051865 | Not Cancer Driver | No | 23 | 0.0756578947368421 | 136 | 11 | 0.0361842105263157 | 0 |
RNF122-201 | RNF122 | Q9H9V4 | RING finger protein 122 | chr8 | GO:0051865 | Not Cancer Driver | No | 16 | 0.1032258064516129 | 0 | 0 | 0.0 | 0 |
RNF13-203 | RNF13 | O43567 | E3 ubiquitin-protein ligase RNF13 | chr3 | GO:0051865 | Not Cancer Driver | No | 27 | 0.0708661417322834 | 108 | 13 | 0.0341207349081364 | 2 |
RNF133-201 | RNF133 | Q8WVZ7 | E3 ubiquitin-protein ligase RNF133 | chr7 | GO:0051865 | Not Cancer Driver | No | 60 | 0.1595744680851064 | 60 | 3 | 0.0079787234042553 | 0 |
RNF141-201 | RNF141 | Q8WVD5 | RING finger protein 141 | chr11 | GO:0051865 | Not Cancer Driver | No | 21 | 0.0913043478260869 | 48 | 3 | 0.0130434782608695 | 0 |
RNF146-202 | RNF146 | Q9NTX7 | E3 ubiquitin-protein ligase RNF146 | chr6 | GO:0051865 | Not Cancer Driver | No | 23 | 0.064066852367688 | 206 | 15 | 0.0417827298050139 | 0 |
RNF181-201 | RNF181 | Q9P0P0 | E3 ubiquitin-protein ligase RNF181 | chr2 | GO:0051865 | Not Cancer Driver | No | 13 | 0.0849673202614379 | 64 | 6 | 0.0392156862745098 | 0 |
RNF183-207 | RNF183 | Q96D59 | E3 ubiquitin-protein ligase RNF183 | chr9 | GO:0051865 | Not Cancer Driver | No | 19 | 0.0989583333333333 | 29 | 1 | 0.0052083333333333 | 0 |
RNF185-202 | RNF185 | Q96GF1 | E3 ubiquitin-protein ligase RNF185 | chr22 | GO:0051865 | Not Cancer Driver | No | 18 | 0.09375 | 82 | 10 | 0.0520833333333333 | 0 |
RNF186-201 | RNF186 | Q9NXI6 | E3 ubiquitin-protein ligase RNF186 | chr1 | GO:0051865 | Not Cancer Driver | No | 19 | 0.0837004405286343 | 11 | 0 | 0.0 | 0 |
RNF187-201 | RNF187 | Q5TA31 | E3 ubiquitin-protein ligase RNF187 | chr1 | GO:0051865 | Not Cancer Driver | No | 0 | 0.0 | 104 | 0 | 0.0 | 0 |
RNF19B-203 | RNF19B | Q6ZMZ0 | E3 ubiquitin-protein ligase RNF19B | chr1 | GO:0051865 | Not Cancer Driver | No | 45 | 0.0614754098360655 | 344 | 20 | 0.0273224043715847 | 0 |
RNF208-201 | RNF208 | Q9H0X6 | RING finger protein 208 | chr9 | GO:0051865 | Not Cancer Driver | No | 16 | 0.0613026819923371 | 114 | 6 | 0.0229885057471264 | 0 |
RNF213-220 | RNF213 | Q63HN8 | E3 ubiquitin-protein ligase RNF213 | chr17 | GO:0051865 | Census, Compendium | Yes | 408 | 0.0783560591511426 | 628 | 60 | 0.011522949875168 | 3 |
RNF220-203 | RNF220 | Q5VTB9 | E3 ubiquitin-protein ligase RNF220 | chr1 | GO:0051865 | Not Cancer Driver | No | 72 | 0.127208480565371 | 402 | 48 | 0.0848056537102473 | 2 |
RNF4-201 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | GO:0051865 | Not Cancer Driver | No | 9 | 0.0473684210526315 | 120 | 5 | 0.0263157894736842 | 0 |
RNF41-201 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0051865 | Not Cancer Driver | No | 36 | 0.113564668769716 | 33 | 2 | 0.0063091482649842 | 0 |
RNF8-202 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0051865 | Not Cancer Driver | No | 31 | 0.0639175257731958 | 226 | 14 | 0.0288659793814433 | 0 |
RNFT1-201 | RNFT1 | Q5M7Z0 | E3 ubiquitin-protein ligase RNFT1 | chr17 | GO:0051865 | Not Cancer Driver | No | 22 | 0.0505747126436781 | 117 | 13 | 0.0298850574712643 | 0 |
SH3RF1-201 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0051865 | Not Cancer Driver | No | 83 | 0.0934684684684684 | 588 | 55 | 0.0619369369369369 | 0 |
SH3RF2-201 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0051865 | Not Cancer Driver | No | 125 | 0.1714677640603566 | 460 | 80 | 0.1097393689986282 | 0 |
SH3RF3-201 | SH3RF3 | Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 | chr2 | GO:0051865 | Not Cancer Driver | No | 78 | 0.0884353741496598 | 566 | 45 | 0.0510204081632653 | 0 |
STUB1-201 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0051865 | Not Cancer Driver | No | 29 | 0.0957095709570957 | 113 | 11 | 0.0363036303630363 | 11 |
TRAF2-201 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0051865 | Not Cancer Driver | No | 51 | 0.1017964071856287 | 4 | 1 | 0.0019960079840319 | 0 |
TRAF6-202 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0051865 | Not Cancer Driver | No | 51 | 0.0977011494252873 | 62 | 5 | 0.0095785440613026 | 0 |
TRIM11-201 | TRIM11 | Q96F44 | E3 ubiquitin-protein ligase TRIM11 | chr1 | GO:0051865 | Not Cancer Driver | No | 46 | 0.0982905982905982 | 132 | 16 | 0.0341880341880341 | 0 |
TRIM13-202 | TRIM13 | O60858 | E3 ubiquitin-protein ligase TRIM13 | chr13 | GO:0051865 | Not Cancer Driver | No | 41 | 0.1007371007371007 | 1 | 0 | 0.0 | 0 |
TRIM17-204 | TRIM17 | Q9Y577 | E3 ubiquitin-protein ligase TRIM17 | chr1 | GO:0051865 | Not Cancer Driver | No | 53 | 0.1111111111111111 | 129 | 16 | 0.0335429769392033 | 0 |
TRIM21-201 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0051865 | Not Cancer Driver | No | 63 | 0.1326315789473684 | 49 | 8 | 0.0168421052631578 | 0 |
TRIM37-201 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | GO:0051865 | Not Cancer Driver | No | 89 | 0.0923236514522821 | 493 | 42 | 0.0435684647302904 | 3 |
TRIM52-205 | TRIM52 | Q96A61 | E3 ubiquitin-protein ligase TRIM52 | chr5 | GO:0051865 | Not Cancer Driver | No | 11 | 0.037037037037037 | 147 | 5 | 0.0168350168350168 | 0 |
TRIM58-201 | TRIM58 | Q8NG06 | E3 ubiquitin-protein ligase TRIM58 | chr1 | GO:0051865 | Not Cancer Driver | No | 163 | 0.3353909465020576 | 84 | 32 | 0.0658436213991769 | 0 |
TRIM68-201 | TRIM68 | Q6AZZ1 | E3 ubiquitin-protein ligase TRIM68 | chr11 | GO:0051865 | Not Cancer Driver | No | 56 | 0.1154639175257732 | 37 | 7 | 0.0144329896907216 | 0 |
TRIM71-201 | TRIM71 | Q2Q1W2 | E3 ubiquitin-protein ligase TRIM71 | chr3 | GO:0051865 | Not Cancer Driver | No | 86 | 0.0990783410138248 | 163 | 13 | 0.0149769585253456 | 2 |
UBE2B-201 | UBE2B | P63146 | Ubiquitin-conjugating enzyme E2 B | chr5 | GO:0051865 | Not Cancer Driver | No | 9 | 0.0592105263157894 | 68 | 4 | 0.0263157894736842 | 0 |
UBE2D2-201 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | GO:0051865 | Compendium | Yes | 14 | 0.0952380952380952 | 13 | 1 | 0.0068027210884353 | 0 |
UBE2D3-210 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | GO:0051865 | Not Cancer Driver | No | 15 | 0.1020408163265306 | 13 | 3 | 0.0204081632653061 | 0 |
UBE2T-205 | UBE2T | Q9NPD8 | Ubiquitin-conjugating enzyme E2 T | chr1 | GO:0051865 | Not Cancer Driver | No | 11 | 0.0558375634517766 | 97 | 8 | 0.0406091370558375 | 1 |
UBE3A-228 | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | GO:0051865 | Not Cancer Driver | No | 90 | 0.1028571428571428 | 136 | 16 | 0.0182857142857142 | 0 |
UBE3D-203 | UBE3D | Q7Z6J8 | E3 ubiquitin-protein ligase E3D | chr6 | GO:0051865 | Not Cancer Driver | No | 38 | 0.0976863753213367 | 9 | 3 | 0.0077120822622107 | 0 |
UHRF1-208 | UHRF1 | Q96T88 | E3 ubiquitin-protein ligase UHRF1 | chr19 | GO:0051865 | Not Cancer Driver | No | 0 | 0.0 | 353 | 0 | 0.0 | 0 |
UHRF2-201 | UHRF2 | Q96PU4 | E3 ubiquitin-protein ligase UHRF2 | chr9 | GO:0051865 | Not Cancer Driver | No | 67 | 0.0835411471321695 | 254 | 16 | 0.0199501246882793 | 0 |
WWP2-202 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | GO:0051865 | Not Cancer Driver | No | 87 | 0.1 | 423 | 46 | 0.0528735632183908 | 0 |