Filter in search result
Please select a valid state.

Total number of protein in "GO:0060070" GO term:  103

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADGRA2-202 ADGRA2 Q96PE1 Adhesion G protein-coupled receptor A2 chr8 GO:0060070 Not Cancer Driver No 112 0.0837070254110612 419 22 0.0164424514200298 0
AXIN1-201 AXIN1 O15169 Axin-1 chr16 GO:0060070 Census, Compendium Yes 91 0.105568445475638 623 69 0.0800464037122969 4
AXIN2-201 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0060070 Census, Compendium Yes 82 0.0972716488730723 551 51 0.0604982206405693 0
BCL9-201 BCL9 O00512 B-cell CLL/lymphoma 9 protein chr1 GO:0060070 Census, Compendium Yes 164 0.1150070126227209 1431 164 0.1150070126227209 0
BCL9L-205 BCL9L Q86UU0 B-cell CLL/lymphoma 9-like protein chr11 GO:0060070 Census, Compendium Yes 166 0.1107404936624416 1501 166 0.1107404936624416 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 GO:0060070 Not Cancer Driver No 23 0.1292134831460674 2 0 0.0 0
CBY1-201 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 GO:0060070 Not Cancer Driver No 9 0.0714285714285714 98 7 0.0555555555555555 0
COL6A1-201 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 GO:0060070 Not Cancer Driver No 68 0.0661478599221789 436 23 0.0223735408560311 12
CSNK1E-203 CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0060070 Not Cancer Driver No 44 0.1057692307692307 133 13 0.03125 0
CTDNEP1-210 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 GO:0060070 Not Cancer Driver No 12 0.0491803278688524 0 0 0.0 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 GO:0060070 Census, Compendium Yes 363 0.4647887323943662 288 291 0.3725992317541613 11
DACT3-202 DACT3 Q96B18 Dapper homolog 3 chr19 GO:0060070 Not Cancer Driver No 11 0.0174880763116057 550 7 0.0111287758346581 0
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0060070 Not Cancer Driver No 106 0.1241217798594847 520 65 0.0761124121779859 0
DIXDC1-201 DIXDC1 Q155Q3 Dixin chr11 GO:0060070 Not Cancer Driver No 55 0.0805270863836017 498 44 0.0644216691068814 0
DKK1-201 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0060070 Not Cancer Driver No 48 0.1804511278195488 48 8 0.0300751879699248 0
DKKL1-201 DKKL1 Q9UK85 Dickkopf-like protein 1 chr19 GO:0060070 Not Cancer Driver No 36 0.1487603305785124 138 24 0.0991735537190082 0
DVL1-201 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0060070 Not Cancer Driver No 42 0.0604316546762589 434 16 0.0230215827338129 0
DVL2-201 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0060070 Not Cancer Driver No 72 0.0978260869565217 515 52 0.0706521739130434 0
DVL3-201 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0060070 Not Cancer Driver No 58 0.0810055865921787 437 31 0.0432960893854748 0
EDA-203 EDA Q92838 Ectodysplasin-A chrX GO:0060070 Not Cancer Driver No 17 0.0434782608695652 243 1 0.0025575447570332 58
EDN1-201 EDN1 P05305 Endothelin-1 chr6 GO:0060070 Not Cancer Driver No 27 0.1273584905660377 98 16 0.0754716981132075 3
EDNRA-209 EDNRA P25101 Endothelin-1 receptor chr4 GO:0060070 Not Cancer Driver No 52 0.1217798594847775 21 5 0.0117096018735363 2
EDNRB-207 EDNRB P24530 Endothelin receptor type B chr13 GO:0060070 Not Cancer Driver No 94 0.2126696832579185 56 13 0.0294117647058823 9
EXT1-201 EXT1 Q16394 Exostosin-1 chr8 GO:0060070 Census Yes 75 0.1005361930294906 60 7 0.0093833780160857 8
FGF2-201 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0060070 Not Cancer Driver No 17 0.0590277777777777 183 5 0.0173611111111111 0
FGF9-201 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0060070 Not Cancer Driver No 33 0.1586538461538461 43 8 0.0384615384615384 1
FOXD1-202 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0060070 Not Cancer Driver No 7 0.0150537634408602 262 5 0.010752688172043 0
FOXO1-201 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0060070 Census, Compendium Yes 52 0.0793893129770992 586 51 0.0778625954198473 0
FOXO3-202 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0060070 Census, Compendium Yes 54 0.0802377414561664 597 50 0.0742942050520059 0
FRAT1-201 FRAT1 Q92837 Proto-oncogene FRAT1 chr10 GO:0060070 Not Cancer Driver No 6 0.021505376344086 266 6 0.021505376344086 0
FRZB-201 FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0060070 Not Cancer Driver No 45 0.1384615384615384 31 5 0.0153846153846153 1
FZD1-201 FZD1 Q9UP38 Frizzled-1 chr7 GO:0060070 Not Cancer Driver No 65 0.1004636785162287 133 2 0.0030911901081916 0
FZD10-201 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0060070 Not Cancer Driver No 111 0.1910499139414802 65 13 0.0223752151462994 0
FZD2-201 FZD2 Q14332 Frizzled-2 chr17 GO:0060070 Not Cancer Driver No 73 0.1292035398230088 47 6 0.0106194690265486 2
FZD3-201 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0060070 Not Cancer Driver No 44 0.066066066066066 140 10 0.015015015015015 0
FZD4-201 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0060070 Not Cancer Driver No 40 0.074487895716946 33 5 0.0093109869646182 17
FZD5-201 FZD5 Q13467 Frizzled-5 chr2 GO:0060070 Not Cancer Driver No 39 0.0666666666666666 58 3 0.0051282051282051 0
FZD6-201 FZD6 O60353 Frizzled-6 chr8 GO:0060070 Not Cancer Driver No 60 0.0849858356940509 173 14 0.0198300283286118 1
FZD7-201 FZD7 O75084 Frizzled-7 chr2 GO:0060070 Not Cancer Driver No 72 0.1254355400696864 22 1 0.0017421602787456 0
FZD8-201 FZD8 Q9H461 Frizzled-8 chr10 GO:0060070 Not Cancer Driver No 41 0.0590778097982708 146 0 0.0 0
FZD9-201 FZD9 O00144 Frizzled-9 chr7 GO:0060070 Not Cancer Driver No 48 0.0812182741116751 61 0 0.0 0
GPC3-201 GPC3 P51654 Glypican-3 chrX GO:0060070 Census Yes 55 0.0948275862068965 87 7 0.0120689655172413 1
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0060070 Not Cancer Driver No 34 0.0809523809523809 148 6 0.0142857142857142 0
HESX1-201 HESX1 Q9UBX0 Homeobox expressed in ES cells 1 chr3 GO:0060070 Not Cancer Driver No 24 0.1297297297297297 59 7 0.0378378378378378 6
ISL1-201 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0060070 Not Cancer Driver No 73 0.2091690544412607 181 41 0.1174785100286533 0
JUP-203 JUP P14923 Junction plakoglobin chr17 GO:0060070 Not Cancer Driver No 81 0.1087248322147651 242 24 0.0322147651006711 0
KLF4-201 KLF4 O43474 Krueppel-like factor 4 chr9 GO:0060070 Census, Compendium Yes 41 0.0855949895615866 417 25 0.0521920668058455 0
LATS2-201 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:0060070 Census, Compendium Yes 101 0.0928308823529411 690 57 0.0523897058823529 0
LEF1-201 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0060070 Census Yes 51 0.1278195488721804 372 47 0.1177944862155388 0
LRP5-201 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0060070 Not Cancer Driver No 196 0.1213622291021671 189 24 0.014860681114551 54
LRP6-201 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0060070 Not Cancer Driver No 148 0.0917544947303161 255 27 0.0167389956602603 5
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0060070 Not Cancer Driver No 402 0.1590819153146023 91 13 0.0051444400474871 20
NDP-202 NDP Q00604 Norrin chrX GO:0060070 Not Cancer Driver No 11 0.0827067669172932 0 0 0.0 45
NID1-201 NID1 P14543 Nidogen-1 chr1 GO:0060070 Not Cancer Driver No 195 0.1563753007217321 342 62 0.0497193263833199 0
NR4A2-201 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0060070 Not Cancer Driver No 84 0.1404682274247491 262 32 0.0535117056856187 3
PTEN-201 PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0060070 Census, Compendium Yes 425 1.054590570719603 76 5 0.0124069478908188 37
PYGO1-201 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 GO:0060070 Not Cancer Driver No 40 0.0954653937947494 364 36 0.0859188544152744 0
PYGO2-202 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 GO:0060070 Not Cancer Driver No 44 0.1083743842364532 341 39 0.0960591133004926 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 GO:0060070 Not Cancer Driver No 20 0.0930232558139534 67 9 0.041860465116279 0
RARG-203 RARG P13631 Retinoic acid receptor gamma chr12 GO:0060070 Not Cancer Driver No 69 0.1519823788546255 164 24 0.052863436123348 0
RECK-201 RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 GO:0060070 Not Cancer Driver No 81 0.0834191555097837 9 2 0.0020597322348094 0
RSPO2-201 RSPO2 Q6UXX9 R-spondin-2 chr8 GO:0060070 Census Yes 67 0.2757201646090535 41 5 0.0205761316872428 1
RSPO3-201 RSPO3 Q9BXY4 R-spondin-3 chr6 GO:0060070 Census Yes 26 0.0955882352941176 101 6 0.0220588235294117 0
RYK-208 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0060070 Not Cancer Driver No 38 0.0626029654036243 85 3 0.0049423393739703 0
SDC1-201 SDC1 P18827 Syndecan-1 chr2 GO:0060070 Not Cancer Driver No 24 0.0774193548387096 263 23 0.0741935483870967 0
SFRP1-201 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0060070 Not Cancer Driver No 31 0.0987261146496815 39 4 0.0127388535031847 0
SFRP2-201 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0060070 Not Cancer Driver No 37 0.1254237288135593 1 0 0.0 0
SFRP4-201 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0060070 Census Yes 59 0.1705202312138728 69 15 0.0433526011560693 0
SFRP5-201 SFRP5 Q5T4F7 Secreted frizzled-related protein 5 chr10 GO:0060070 Not Cancer Driver No 16 0.0504731861198738 7 2 0.0063091482649842 0
SHH-201 SHH Q15465 Sonic hedgehog protein chr7 GO:0060070 Not Cancer Driver No 36 0.0779220779220779 139 11 0.0238095238095238 69
SIAH1-203 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0060070 Not Cancer Driver No 22 0.0780141843971631 28 2 0.0070921985815602 5
SIAH2-201 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0060070 Not Cancer Driver No 34 0.1049382716049382 68 2 0.0061728395061728 0
SNAI1-201 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0060070 Not Cancer Driver No 41 0.1553030303030303 98 8 0.0303030303030303 0
SOST-201 SOST Q9BQB4 Sclerostin chr17 GO:0060070 Not Cancer Driver No 24 0.1126760563380281 90 10 0.0469483568075117 2
SOSTDC1-201 SOSTDC1 Q6X4U4 Sclerostin domain-containing protein 1 chr7 GO:0060070 Not Cancer Driver No 14 0.0679611650485436 72 1 0.0048543689320388 0
SOX9-201 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0060070 Compendium Yes 69 0.1355599214145383 497 66 0.1296660117878192 13
STK3-201 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0060070 Not Cancer Driver No 48 0.0977596741344195 241 22 0.0448065173116089 0
STK4-202 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0060070 Not Cancer Driver No 49 0.1006160164271047 233 20 0.0410677618069815 0
TCF7-201 TCF7 P36402 Transcription factor 7 chr5 GO:0060070 Not Cancer Driver No 26 0.0677083333333333 307 23 0.0598958333333333 0
TCF7L1-201 TCF7L1 Q9HCS4 Transcription factor 7-like 1 chr2 GO:0060070 Not Cancer Driver No 45 0.0765306122448979 552 43 0.0731292517006802 0
TCF7L2-206 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0060070 Census, Compendium Yes 76 0.122778675282714 517 62 0.1001615508885298 0
TPTEP2-CSNK1E-201 CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0060070 Not Cancer Driver No 44 0.1057692307692307 133 13 0.03125 0
VPS4B-201 VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:0060070 Not Cancer Driver No 33 0.0743243243243243 195 14 0.0315315315315315 0
WNT1-201 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0060070 Not Cancer Driver No 20 0.054054054054054 25 0 0.0 8
WNT10A-201 WNT10A Q9GZT5 Protein Wnt-10a chr2 GO:0060070 Not Cancer Driver No 30 0.0719424460431654 123 9 0.0215827338129496 10
WNT10B-201 WNT10B O00744 Protein Wnt-10b chr12 GO:0060070 Not Cancer Driver No 45 0.1156812339331619 84 14 0.0359897172236503 2
WNT11-201 WNT11 O96014 Protein Wnt-11 chr11 GO:0060070 Not Cancer Driver No 37 0.1045197740112994 59 3 0.0084745762711864 0
WNT16-201 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0060070 Not Cancer Driver No 37 0.1013698630136986 29 5 0.0136986301369863 0
WNT2-201 WNT2 P09544 Protein Wnt-2 chr7 GO:0060070 Not Cancer Driver No 53 0.1472222222222222 11 1 0.0027777777777777 0
WNT2B-202 WNT2B Q93097 Protein Wnt-2b chr1 GO:0060070 Not Cancer Driver No 49 0.1253196930946291 27 1 0.0025575447570332 0
WNT3-201 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0060070 Not Cancer Driver No 44 0.1239436619718309 34 9 0.0253521126760563 0
WNT3A-201 WNT3A P56704 Protein Wnt-3a chr1 GO:0060070 Not Cancer Driver No 60 0.1704545454545454 37 2 0.0056818181818181 0
WNT4-201 WNT4 P56705 Protein Wnt-4 chr1 GO:0060070 Not Cancer Driver No 25 0.0712250712250712 39 2 0.0056980056980056 5
WNT5A-201 WNT5A P41221 Protein Wnt-5a chr3 GO:0060070 Not Cancer Driver No 42 0.1105263157894736 0 0 0.0 2
WNT5B-202 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0060070 Not Cancer Driver No 55 0.1532033426183844 23 4 0.011142061281337 0
WNT6-201 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0060070 Not Cancer Driver No 26 0.0712328767123287 84 8 0.021917808219178 0
WNT7A-201 WNT7A O00755 Protein Wnt-7a chr3 GO:0060070 Not Cancer Driver No 68 0.1948424068767908 18 6 0.0171919770773638 4
WNT7B-201 WNT7B P56706 Protein Wnt-7b chr22 GO:0060070 Not Cancer Driver No 41 0.1174785100286533 11 1 0.0028653295128939 0
WNT8A-202 WNT8A Q9H1J5 Protein Wnt-8a chr5 GO:0060070 Not Cancer Driver No 36 0.1025641025641025 3 0 0.0 0
WNT8B-201 WNT8B Q93098 Protein Wnt-8b chr10 GO:0060070 Not Cancer Driver No 39 0.1111111111111111 27 4 0.0113960113960113 0
WNT9A-201 WNT9A O14904 Protein Wnt-9a chr1 GO:0060070 Not Cancer Driver No 58 0.1589041095890411 44 7 0.0191780821917808 0
WNT9B-201 WNT9B O14905 Protein Wnt-9b chr17 GO:0060070 Not Cancer Driver No 42 0.1176470588235294 11 6 0.0168067226890756 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0060070 Not Cancer Driver No 41 0.0813492063492063 491 41 0.0813492063492063 0