Total number of protein in "GO:0070269" GO term: 32
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AIM2-202 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0070269 | Not Cancer Driver | No | 54 | 0.1574344023323615 | 79 | 17 | 0.0495626822157434 | 0 |
| APIP-201 | APIP | Q96GX9 | Methylthioribulose-1-phosphate dehydratase | chr11 | GO:0070269 | Not Cancer Driver | No | 19 | 0.0785123966942148 | 26 | 1 | 0.0041322314049586 | 0 |
| CASP1-212 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0070269 | Not Cancer Driver | No | 54 | 0.1336633663366336 | 88 | 12 | 0.0297029702970297 | 0 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0070269 | Census | Yes | 19 | 0.0685920577617328 | 64 | 1 | 0.003610108303249 | 0 |
| CASP4-203 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0070269 | Not Cancer Driver | No | 41 | 0.1087533156498673 | 103 | 11 | 0.0291777188328912 | 0 |
| CASP6-201 | CASP6 | P55212 | Caspase-6 | chr4 | GO:0070269 | Not Cancer Driver | No | 19 | 0.0648464163822525 | 24 | 4 | 0.0136518771331058 | 0 |
| CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0070269 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
| DHX9-201 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | GO:0070269 | Compendium | Yes | 125 | 0.0984251968503937 | 332 | 30 | 0.0236220472440944 | 0 |
| DPP9-214 | DPP9 | Q86TI2 | Dipeptidyl peptidase 9 | chr19 | GO:0070269 | Not Cancer Driver | No | 65 | 0.0753186558516801 | 83 | 3 | 0.0034762456546929 | 0 |
| ELANE-201 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0070269 | Not Cancer Driver | No | 31 | 0.1161048689138576 | 18 | 1 | 0.0037453183520599 | 65 |
| GSDMA-201 | GSDMA | Q96QA5 | Gasdermin-A | chr17 | GO:0070269 | Not Cancer Driver | No | 55 | 0.1235955056179775 | 88 | 14 | 0.0314606741573033 | 0 |
| GSDMB-205 | GSDMB | Q8TAX9 | Gasdermin-B | chr17 | GO:0070269 | Not Cancer Driver | No | 32 | 0.0769230769230769 | 84 | 8 | 0.0192307692307692 | 0 |
| GSDMC-201 | GSDMC | Q9BYG8 | Gasdermin-C | chr8 | GO:0070269 | Not Cancer Driver | No | 93 | 0.1830708661417323 | 0 | 0 | 0.0 | 0 |
| GSDMD-201 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:0070269 | Not Cancer Driver | No | 38 | 0.0785123966942148 | 156 | 14 | 0.0289256198347107 | 0 |
| GSDME-214 | GSDME | O60443 | Gasdermin-E | chr7 | GO:0070269 | Not Cancer Driver | No | 64 | 0.1290322580645161 | 14 | 2 | 0.0040322580645161 | 0 |
| GZMA-201 | GZMA | P12544 | Granzyme A | chr5 | GO:0070269 | Not Cancer Driver | No | 55 | 0.2099236641221374 | 5 | 1 | 0.0038167938931297 | 0 |
| GZMB-201 | GZMB | P10144 | Granzyme B | chr14 | GO:0070269 | Not Cancer Driver | No | 31 | 0.1255060728744939 | 103 | 13 | 0.0526315789473684 | 0 |
| IFI27-205 | IFI27 | P40305 | Interferon alpha-inducible protein 27, mitochondrial | chr14 | GO:0070269 | Not Cancer Driver | No | 7 | 0.0573770491803278 | 0 | 0 | 0.0 | 0 |
| MAP3K20-202 | MAP3K20 | Q9NYL2 | Mitogen-activated protein kinase kinase kinase 20 | chr2 | GO:0070269 | Not Cancer Driver | No | 71 | 0.08875 | 296 | 35 | 0.04375 | 2 |
| MEFV-201 | MEFV | O15553 | Pyrin | chr16 | GO:0070269 | Not Cancer Driver | No | 152 | 0.1946222791293214 | 402 | 91 | 0.11651728553137 | 43 |
| NAIP-208 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0070269 | Not Cancer Driver | No | 29 | 0.0206699928724162 | 67 | 4 | 0.0028510334996436 | 0 |
| NINJ1-201 | NINJ1 | Q92982 | Ninjurin-1 | chr9 | GO:0070269 | Not Cancer Driver | No | 14 | 0.0921052631578947 | 29 | 0 | 0.0 | 0 |
| NLRC4-203 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0070269 | Not Cancer Driver | No | 135 | 0.1318359375 | 15 | 1 | 0.0009765625 | 3 |
| NLRP1-208 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0070269 | Not Cancer Driver | No | 169 | 0.1147318397827562 | 341 | 45 | 0.0305498981670061 | 6 |
| NLRP3-201 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0070269 | Not Cancer Driver | No | 287 | 0.2775628626692456 | 65 | 30 | 0.0290135396518375 | 34 |
| NLRP6-201 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0070269 | Not Cancer Driver | No | 68 | 0.0762331838565022 | 205 | 11 | 0.0123318385650224 | 0 |
| NLRP9-201 | NLRP9 | Q7RTR0 | NACHT, LRR and PYD domains-containing protein 9 | chr19 | GO:0070269 | Not Cancer Driver | No | 193 | 0.1947527749747729 | 0 | 0 | 0.0 | 0 |
| PYCARD-201 | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0070269 | Not Cancer Driver | No | 12 | 0.0615384615384615 | 39 | 4 | 0.0205128205128205 | 0 |
| TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0070269 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
| TRIM21-201 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0070269 | Not Cancer Driver | No | 63 | 0.1326315789473684 | 49 | 8 | 0.0168421052631578 | 0 |
| ZBP1-201 | ZBP1 | Q9H171 | Z-DNA-binding protein 1 | chr20 | GO:0070269 | Not Cancer Driver | No | 70 | 0.1631701631701631 | 388 | 60 | 0.1398601398601398 | 0 |
| ZEB2-226 | ZEB2 | O60315 | Zinc finger E-box-binding homeobox 2 | chr2 | GO:0070269 | Not Cancer Driver | No | 229 | 0.1886326194398682 | 859 | 166 | 0.1367380560131795 | 2 |